powerpoint slides for class 3
... incomplete and computational simulations are so time consuming that prediction of protein function based on only a single DNA sequence is at present impossible (at least for a protein of reasonable size). ...
... incomplete and computational simulations are so time consuming that prediction of protein function based on only a single DNA sequence is at present impossible (at least for a protein of reasonable size). ...
Chapter 3
... – Most proteins made of multiple domains that perform different parts of the protein’s function ...
... – Most proteins made of multiple domains that perform different parts of the protein’s function ...
Unit 1 Ch. 1, 17, 18. WHAT IS BIOLOGY?
... tRNA ANTICODONS (anticodons pair with codons) TRANSLATION (tRNA reads mRNA to make a protein) ...
... tRNA ANTICODONS (anticodons pair with codons) TRANSLATION (tRNA reads mRNA to make a protein) ...
The Nature of Genes The Nature of Genes
... • Introns are spliced out of pre-mRNAs to produce the mature mRNA that is translated. • Alternative splicing recognizes different splice sites in different tissue types. • The mature mRNAs in each tissue possess different exons, resulting in different polypeptide products from the same gene. ...
... • Introns are spliced out of pre-mRNAs to produce the mature mRNA that is translated. • Alternative splicing recognizes different splice sites in different tissue types. • The mature mRNAs in each tissue possess different exons, resulting in different polypeptide products from the same gene. ...
CENTRAL DOGMA AND GENE REGULATION
... Codon: the triplicate code found on mRNA that codes for each of the 20 amino acids, for start (methionine) and stop Genetic Code: the inventory of linkages between nucleotide triplets and the amino acids they code for: GENE REGULATION: Determines when a protein is expressed (produced) in a cell. Som ...
... Codon: the triplicate code found on mRNA that codes for each of the 20 amino acids, for start (methionine) and stop Genetic Code: the inventory of linkages between nucleotide triplets and the amino acids they code for: GENE REGULATION: Determines when a protein is expressed (produced) in a cell. Som ...
GENE to PROTEIN
... • First codon decipher was UUU • There are 64 codons • A codon codes for only 1 amino acid The genetic code must have evolved very early in the history of life because it is nearly universal among living organisms. ...
... • First codon decipher was UUU • There are 64 codons • A codon codes for only 1 amino acid The genetic code must have evolved very early in the history of life because it is nearly universal among living organisms. ...
GENE to PROTEIN
... • First codon decipher was UUU • There are 64 codons • A codon codes for only 1 amino acid The genetic code must have evolved very early in the history of life because it is nearly universal among living organisms. ...
... • First codon decipher was UUU • There are 64 codons • A codon codes for only 1 amino acid The genetic code must have evolved very early in the history of life because it is nearly universal among living organisms. ...
lecture notes endomembrane system 4
... 13. Because the oligosaccharide chains are added/modified on the luminal side of the ER and the GA, the distribution of carbohydrate on membrane proteins and lipids is asymmetric. That is within the cell the carbohydrates are on the lumen side, and those on the plasma membrane therefore have the car ...
... 13. Because the oligosaccharide chains are added/modified on the luminal side of the ER and the GA, the distribution of carbohydrate on membrane proteins and lipids is asymmetric. That is within the cell the carbohydrates are on the lumen side, and those on the plasma membrane therefore have the car ...
Organic Compounds
... • Water is the most abundant and important inorganic material, making up 60% - 80% of all cells and 2/3 of body weight ...
... • Water is the most abundant and important inorganic material, making up 60% - 80% of all cells and 2/3 of body weight ...
ppt
... 1. Antibody columns - for specific antigens 2. Cellulose columns - for cellulases 3. Starch columns - for amylases 4. DNA columns - for DNA binding proteins 5. Ligand columns - for specific receptors 6. Metal columns - for proteins that bind metal ions IMAC, or Immobilized Metal ion Affinity Chromat ...
... 1. Antibody columns - for specific antigens 2. Cellulose columns - for cellulases 3. Starch columns - for amylases 4. DNA columns - for DNA binding proteins 5. Ligand columns - for specific receptors 6. Metal columns - for proteins that bind metal ions IMAC, or Immobilized Metal ion Affinity Chromat ...
Ch. 17 - Ltcconline.net
... 6. enzymes are responsible for producing reactions in biochemical pathways. 7. If a person lacks a particular enzyme, they can’t complete the pathway 8. inheriting a defective gene causes lack of particular enzymes. 9. Beadle and Tatum -- 1 gene, 1 protein. Now its 1 gene, 1 polypeptide, but not alw ...
... 6. enzymes are responsible for producing reactions in biochemical pathways. 7. If a person lacks a particular enzyme, they can’t complete the pathway 8. inheriting a defective gene causes lack of particular enzymes. 9. Beadle and Tatum -- 1 gene, 1 protein. Now its 1 gene, 1 polypeptide, but not alw ...
The amino acids, peptide bonds, and the primary structure of proteins
... • Phosphorylation: addition of a phosphate group (PO43-) to a Ser or Tyr residue. • Glycosylation: addition of sugar groups to Asn (Nglycosylation) or Ser (O-glycosylation). • Alteration of chain termini – Removal of N-Met – Acetylation and amidation ...
... • Phosphorylation: addition of a phosphate group (PO43-) to a Ser or Tyr residue. • Glycosylation: addition of sugar groups to Asn (Nglycosylation) or Ser (O-glycosylation). • Alteration of chain termini – Removal of N-Met – Acetylation and amidation ...
Mahoney Abstract for Pathway to Independence Grant
... each vessel segment or local factors such as cell lineage or in nervation – act through specific promoter sequences to determine RGS5 protein expression level. The proposed experiments will identify and characterize the expression mechanism controlling RGS5 expression in arteries. Specifically, the ...
... each vessel segment or local factors such as cell lineage or in nervation – act through specific promoter sequences to determine RGS5 protein expression level. The proposed experiments will identify and characterize the expression mechanism controlling RGS5 expression in arteries. Specifically, the ...
Protein Structure-Function Relationships - IBIVU
... one domain to that of another. • This enhances the enzymatic activity: delivery of intermediate product not by a diffusion process but by active transport ...
... one domain to that of another. • This enhances the enzymatic activity: delivery of intermediate product not by a diffusion process but by active transport ...
Mentor: James A. MacKay Students: Amanda Williams, Holly Sofka
... Students: Amanda Williams, Holly Sofka Project Description: Ribonucleic acid (RNA) is believed to be an important molecule in the evolution of life and has functionally taken on many important biological roles. Given the many functions of RNA, molecular recognition of RNA represents an attractive go ...
... Students: Amanda Williams, Holly Sofka Project Description: Ribonucleic acid (RNA) is believed to be an important molecule in the evolution of life and has functionally taken on many important biological roles. Given the many functions of RNA, molecular recognition of RNA represents an attractive go ...
Chapt 2
... Gly, Pro? What are the levels of protein structure, what types of bonds are important in establishing each structure? What determines the final structure of a protein? When a protein has finished folding what types of amino acids tend to be on the outside? On the inside? Why? What are motifs, how ca ...
... Gly, Pro? What are the levels of protein structure, what types of bonds are important in establishing each structure? What determines the final structure of a protein? When a protein has finished folding what types of amino acids tend to be on the outside? On the inside? Why? What are motifs, how ca ...
Protein Chemistry
... Four levels of protein structure Primary structure: amino acid only. The actual amino acid sequence is specified by the DNA sequence. The primary structure is used to determine genetic relationships with other proteins - AKA homology. Amino acids that are not changed are considered invariant or con ...
... Four levels of protein structure Primary structure: amino acid only. The actual amino acid sequence is specified by the DNA sequence. The primary structure is used to determine genetic relationships with other proteins - AKA homology. Amino acids that are not changed are considered invariant or con ...
Design of Novel Organocatalytic Click Chemistry: Biological and Medicinal Application.
... The ability to visualize biomolecules within living specimen by engineered fluorescence tags has become a major tool in modern biotechnology and cell biology. Encoding fusion proteins with comparatively large fluorescent proteins (FPs) as originally developed by the Chalfie and Tsien groups is curre ...
... The ability to visualize biomolecules within living specimen by engineered fluorescence tags has become a major tool in modern biotechnology and cell biology. Encoding fusion proteins with comparatively large fluorescent proteins (FPs) as originally developed by the Chalfie and Tsien groups is curre ...
2.2 PPT_Proteins and Nucleic Acids
... Proteins look like a twisted up ball of yarn Each amino acid connect together with a peptide ...
... Proteins look like a twisted up ball of yarn Each amino acid connect together with a peptide ...
File - Mrs. LeCompte
... o Metabolism: ENZYMES speed up chemical reactions in cells o Structural support o Transport: carriers in cell membranes and large-scale, like hemoglobin o Defense: Antibodies o Regulation: Hormones and other intercellular messengers o Motion: Contractile proteins (muscles) and intracellular transpor ...
... o Metabolism: ENZYMES speed up chemical reactions in cells o Structural support o Transport: carriers in cell membranes and large-scale, like hemoglobin o Defense: Antibodies o Regulation: Hormones and other intercellular messengers o Motion: Contractile proteins (muscles) and intracellular transpor ...
SOMAscan™: A Quantitative Multiplex Proteomic
... Sample time-tospin ranges from .5 hours (beige) to 20 hours (blue) ...
... Sample time-tospin ranges from .5 hours (beige) to 20 hours (blue) ...
Lecture 12/13 - Intracellular Transport + Cytoskeleton
... 5.) What is myosin classified as? How does it perform its function? What reaction is involved? 6.) What are 3 different types of movement that can occur through actin-myosin interactions? 7.) What is the primary protein that forms intermediate filaments (that we discussed)? What are two functions of ...
... 5.) What is myosin classified as? How does it perform its function? What reaction is involved? 6.) What are 3 different types of movement that can occur through actin-myosin interactions? 7.) What is the primary protein that forms intermediate filaments (that we discussed)? What are two functions of ...
SR protein
SR proteins are a conserved family of proteins involved in RNA splicing. SR proteins are named because they contain a protein domain with long repeats of serine and arginine amino acid residues, whose standard abbreviations are ""S"" and ""R"" respectively. SR proteins are 50-300 amino acids in length and composed of two domains, the RNA recognition motif (RRM) region and the RS binding domain. SR proteins are more commonly found in the nucleus than the cytoplasm, but several SR proteins are known to shuttle between the nucleus and the cytoplasm.SR proteins were discovered in the 1990s in Drosophila and in amphibian oocytes, and later in humans. In general, metazoans appear to have SR proteins and unicellular organisms lack SR proteins.SR proteins are important in constitutive and alternative pre-mRNA splicing, mRNA export, genome stabilization, nonsense-mediated decay, and translation. SR proteins alternatively splice pre-mRNA by preferentially selecting different splice sites on the pre-mRNA strands to create multiple mRNA transcripts from one pre-mRNA transcript. Once splicing is complete the SR protein may or may not remain attached to help shuttle the mRNA strand out of the nucleus. As RNA Polymerase II is transcribing DNA into RNA, SR proteins attach to newly made pre-mRNA to prevent the pre-mRNA from binding to the coding DNA strand to increase genome stabilization. Topoisomerase I and SR proteins also interact to increase genome stabilization. SR proteins can control the concentrations of specific mRNA that is successfully translated into protein by selecting for nonsense-mediated decay codons during alternative splicing. SR proteins can alternatively splice NMD codons into its own mRNA transcript to auto-regulate the concentration of SR proteins. Through the mTOR pathway and interactions with polyribosomes, SR proteins can increase translation of mRNA.Ataxia telangiectasia, neurofibromatosis type 1, several cancers, HIV-1, and spinal muscular atrophy have all been linked to alternative splicing by SR proteins.