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Chapter 12
Chapter 12

... Absence of the lac repressor is essential but not sufficient for effective transcription of the lac operon.  The activity of RNA polymerase also depends on the presence of another DNA-binding protein called catabolite activator protein or CAP. Like the lac repressor, CAP has two types of binding si ...
From Gene to Protein
From Gene to Protein

...  Uracil (U) replaces thymine (T) when pairing to adenine (A)  Attaches to promoter (start of gene) and stops at terminator (end of gene) ...
Introduction and Review
Introduction and Review

... Introns are removed, and the exons are spliced together, by ribonucleoprotein particles called spliceosomes. mRNA contains a “leader sequence” at its 5’ end, before the coding region. The coding region begins with a translational initiation codon (AUG). A methylated guanosine cap is added to the 5’ ...
RNA and Protein
RNA and Protein

... has thymine has a deoxyribose sugar ...
CH7 DNAtoProtein
CH7 DNAtoProtein

... expression in bacteria • Operon consists of three genes needed to degrade lactose • Repressor gene(codes for repressor protein) outside of operon coding region inhibits transcription unless something else bind to the repressor protein ...
Protein Synthesis
Protein Synthesis

Lecture8
Lecture8

document
document

... the production of proteins through RNA. • In the 1960’s, the code was deciphered and genes were thought of as this code. • But, there is more to genes than a code for proteins. Genes perform many functions, but must be controlled and regulated in order to do so. ...
Regulation of Gene Expression
Regulation of Gene Expression

... Alternative RNA splicing – where different mRNA molecules are produced from the same primary transcript, depending on which RNA segments are treated as exons and which as introns. Regulatory proteins specific to a cell type control intronexon choices by binding to regulatory sequences within the pri ...
Powerpoint - rlsmart.net
Powerpoint - rlsmart.net

... C. Allele-one specific form of a gene (all found at the same locus) -Example: Everyone has the gene for eye color. The possible alleles are blue, brown, green, etc. ...
Eukaryotic transcriptional control
Eukaryotic transcriptional control

... Heterodimeric transcription factors increase regulatory diversity and gene-control options (a) Many transcription factors (e.g. b-Zip and helix-loop-helix proteins) can form both homodimers or heterodimers with other members of the same class. (b) In the hypothetical example shown, transcription fa ...
pGLO™ Transformation
pGLO™ Transformation

... What is a plasmid? • A circular piece of autonomously replicating DNA • Originally evolved by bacteria • May express antibiotic resistance gene or be modified to express proteins of ...
Aim 24: How does DNA code for the production of proteins through
Aim 24: How does DNA code for the production of proteins through

... Date: Aim 24: How does DNA code for the production of proteins through the process of translation? Recall: Protein synthesis begins with the transcription of DNA to mRNA (The RNA that is synthesized from a DNA molecule). This process occurs in the nucleus, allowing the mRNA strand to leave the nucle ...
No Slide Title
No Slide Title

... nitric oxide synthase (iNOS, macNOS, Type II NOS) following exposure to certain cytokines, such as interferon- (IFN-). The IFN- receptor signals through the Janus kinase (JAK) family and signal transducers and activators of transcription (STAT) proteins. Receptor occupation and dimerization induc ...
DNA Technology
DNA Technology

... protein product • In eukaryotes, there is no universal regulatory mechanism that controls the expression of coding genes. (as apposed to prokaryotes) – Regulation is possible at any point in the pathway from gene to functional protein ...
foga i - is there such a thing as a gene? = formatting the
foga i - is there such a thing as a gene? = formatting the

... * Systemic (modular-interactive) nature of each protein molecule and DNA element * Weak interactions, specific binding & cooperativity essential aspects of molecular computations in cells * Layering of weak and “fuzzy” interactions provides overall precision to integrated cellular responses * Allost ...
Chapter 13- RNA and Protein Synthesis
Chapter 13- RNA and Protein Synthesis

... effect, or can negatively disrupt gene function ...
DNA and Gene Expression
DNA and Gene Expression

... • Long understood that eukaryote genes composed of short exons separated by long introns • Introns transcribed to RNA that is spliced out before proteins produced • Now know splicing for a gene-containing locus can be done in multiple ways – Individual exons left out of final product – Only portions ...
Chapter 13- RNA and Protein Synthesis
Chapter 13- RNA and Protein Synthesis

... effect, or can negatively disrupt gene function ...
HOW ARE PROTEINS MADE?
HOW ARE PROTEINS MADE?

Gene Technology - Byron Senior High School
Gene Technology - Byron Senior High School

... • We can pick out one small area of interest and amplify (make lots of copies of) that area to work with ...
Enzyme Induction
Enzyme Induction

... One classic model of the regulation of gene expression is the lac operon in bacteria. ...
Dairy Jepoardy 3
Dairy Jepoardy 3

... Term that describes a gene or DNA fragment known to be linked to a gene of interest. ...
Analysis of Microarray Data Using R
Analysis of Microarray Data Using R

... Su et al ( PNAS 2004) hybridized 150 samples from 61 tissues to Affymetrix U133A and custom arrays Variation in gene expression (as proportion of transcriptome) 95% show at least one 2-fold change among 61 tissues 37% show more than 2-fold differences between lowest 10% and highest 10% ...
Powerpoint Presentation: The Gene
Powerpoint Presentation: The Gene

... © 2010 Paul Billiet ODWS ...
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Silencer (genetics)

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