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mRNA
mRNA

... Codons: Triplets of Bases • The flow of information from gene to protein is based on a triplet code: a series of nonoverlapping, three-nucleotide words • These triplets are the smallest units of uniform length that can code for all the amino acids • Example: AGT at a particular position on a DNA st ...
Gene Section FOXA1 (forkhead box A1)  Atlas of Genetics and Cytogenetics
Gene Section FOXA1 (forkhead box A1) Atlas of Genetics and Cytogenetics

... domain in a winged helix-loop-helix configuration. Both N-terminus and C-terminus have transactivation domains. In silico analysis revealed 11 putative acetylation sites; acetylation sites in the DNA binding domain inhibit interaction with chromatin. The Nterminus has a putative caseine kinase 1 pho ...
Chapter 17 Protein Synthesis
Chapter 17 Protein Synthesis

... Termination of Transcription • The mechanisms of termination are different in bacteria and eukaryotes • In bacteria, the polymerase stops transcription at the end of the terminator and the mRNA can be translated without further modification • In eukaryotes, RNA polymerase II transcribes the polyade ...
Protein Synthesis II
Protein Synthesis II

... Crystal structures of the 70S ribosome with translation elongation factors EF-Tu and EF-G. During protein synthesis, EF-Tu (periwinkle blue) delivers an aminoacyl tRNA (green) to the ribosome for each amino acid indicated by the mRNA. EF-G helps move the mRNA and tRNAs through the ribosome. ...
Gene Section CREB3L2  (cAMP  responsive  element  binding
Gene Section CREB3L2 (cAMP responsive element binding

... CREM, ATF1, ATF6 and CREBL1. The leucine zipper motif of CREB3L2 is similar to that in CREB3L3 and CREB3L4 (pattern L-X6-C-X6-L-X6-L-X6-L-X6-L). It contains six repeats and consists of five leucines and one cysteine at the second heptad position (amino acid 328) of the leucine zipper. Downstream of ...
Regulation of Cell Cycle
Regulation of Cell Cycle

... The mutations probably lead to the aberrant kinase activity and defective transcriptional elongation and/or mRNA processing of certain genes Cdk12 proposed to be a novel tumor suppressor ...
The nucleotide sequence of a gene is colinear with the amino acid
The nucleotide sequence of a gene is colinear with the amino acid

... Bind to enhancer DNA in specific ways Interact with other proteins to activate and increase transcription as much as 100-fold above basal levels ...
6 Protein_Synthesis - bloodhounds Incorporated
6 Protein_Synthesis - bloodhounds Incorporated

... There is no DNA template for this tail? Poly A tails are found on most mRNA molecules but not all (ex. histones mRNA have no poly A tail). In general, a eukaryotic mRNA molecule is longer than the required transcript. The enzyme RNA endonuclease cleaves the molecule at the poly(A) addition site to g ...
Protein Synthesis
Protein Synthesis

... Many eukaryotic genes code for a set of closely related polypeptides in a process called alternative splicing. ...
Chapter 17 lecture notes
Chapter 17 lecture notes

... Many eukaryotic genes code for a set of closely related polypeptides in a process called alternative splicing. ...
Introduction - Cedar Crest College
Introduction - Cedar Crest College

... In prokaryotes, the promoter is a DNA recognition sequence about 40 bp from the 5 initiation point and a TATA box (area rich in AT base pairs) just upstream from the intersection point. ...
Document
Document

... being synthesized is bound by a cap-synthesizing complex associated with RNA polymerase. This enzymatic complex catalyzes the chemical reactions that are required for mRNA capping. ...
Gene7-16
Gene7-16

... Alu family is a set of dispersed, related sequences, each ~300 bp long, in the human genome. The individual members have Alu cleavage sites at each end (hence the name). Processed pseudogene is an inactive gene copy that lacks introns, contrasted with the interrupted structure of the active gene. Su ...
CHAPTER 10
CHAPTER 10

... 10.4 DNA replication depends on specific base pairing – DNA replication follows a semiconservative model – The two DNA strands separate – Each strand is used as a pattern to produce a complementary strand, using specific base pairing – Each new DNA helix has one old strand with one new strand – A b ...
Why genes are regulated?
Why genes are regulated?

... Gene activator: AR1 (activating region 1) region within the C-terminal domain, which interacts with the C-terminal domain of the RNAP alpha subunit (aCTD); AR2 (activating region 2) region within the N-terminal domain, which interacts with the N-terminal domain of RNAP alpha subunit (aNTD); AR3 (act ...
pdf
pdf

... ATPase and kinase activities; ...
RNA - Southgate Schools
RNA - Southgate Schools

... • RNA polymerase uses one strand of DNA as a template and nucleotides are assembled into a strand of RNA. ...
practice making a protein from dna
practice making a protein from dna

... Look up each 3 letter codon on the table of amino acids and write down the three letter abbreviation for each amino acid. Do this next to the word "Protein" (Amino acids can be written as words or abbreviations like this: Arginine or Arg or R) It should look like MET - ARG - ... - ... - GLN STOP (bu ...
4. Transcription in Detail
4. Transcription in Detail

... The correct amino acids must be _________________to the polypeptide-building site. _______________________delivers the amino acids It is a small single-stranded nucleic acid whose structure resembles a _____________ At one _____ of tRNA a sequence of three bases (the ______________) recognizes the c ...
Outlines_Ch14
Outlines_Ch14

... • The DNA-binding region of repressor at OR2 contacts RNA polymerase and stabilizes its binding to PRM. • This is the basis for the autogenous control of repressor ...
DNA to Protein - Seabreeze High School
DNA to Protein - Seabreeze High School

... Things to think About & Discuss 1. What if a mutation occurs in the DNA? Explain how could that affect the organism’s protein? 2. What if a mutation occurs in 3rd base of the codon? Will it always code for a different amino acid? Explain. ...
DNA
DNA

... • Define genetics, genome, chromosome, gene, genetic code, genotype, phenotype, and genomics. • Describe how DNA serves as genetic information. • Describe the process of DNA replication. • Describe protein synthesis, including transcription, RNA processing, and translation. • Describe the operon mod ...
Chapter 17. - Biology Junction
Chapter 17. - Biology Junction

... decoded into the sequence of amino acids ...
Lecture Notes with Key Figures PowerPoint - HMartin
Lecture Notes with Key Figures PowerPoint - HMartin

... • Transcription in Eukaryotes Differs from Prokaryotic Transcription in Several Ways • Occurs in nucleus and is not coupled to translation. • Requires chromatin remodeling. • In addition to promoters, enhancers also influence transcription regulation. • Eukaryotic mRNAs require processing to produce ...
Pa I I, hl.  L.   Blasticidin-S: on... Cycloheximide  has been used widely  as  ...
Pa I I, hl. L. Blasticidin-S: on... Cycloheximide has been used widely as ...

... in light microscopic studies. 4. Not only spindle fiben (which attach to chromatin regions), but also a tightly compressed longitudinal bundle of filaments (which stretcher the late telophase daughter nuclei ) is seen. This filament bundle may be similar to the “Zentralrtrong” described by Girbordt. ...
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RNA polymerase II holoenzyme

RNA polymerase II holoenzyme is a form of eukaryotic RNA polymerase II that is recruited to the promoters of protein-coding genes in living cells. It consists of RNA polymerase II, a subset of general transcription factors, and regulatory proteins known as SRB proteins.
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