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Bio 402/502 Section II, Lecture 1
Bio 402/502 Section II, Lecture 1

... • Three RNA polymerases in eukaryotes: RNA Pol I: 5.8S, 18S, and 28S rRNA genes RNA Pol II: all protein-encoding genes, snoRNA genes, some snRNA genes RNA Pol III: tRNA genes, 5S rRNA genes, some snRNA and small RNA genes ...
Alesandra Espinoza - ERCC-6 Cockayne Syndrome CSB
Alesandra Espinoza - ERCC-6 Cockayne Syndrome CSB

... The following two are significant hits because they discover function and sequence similarity. The first one is significant because it brings up the TATA binding protein. This binding protein is a general transcription factor that binds specifically to a DNA sequence called the TATA box. TBP, along ...
DNA Structure, Replication, and Repair
DNA Structure, Replication, and Repair

... 2. RNA polymerase untwists DNA and joins RNA nucleotides (DNA rejoins as RNA strand peels away) 3. Prokaryotes – termination at a DNA certain DNA sequence Eukaryotes – RNA polymerase goes beyond termination sequence (AAUAAA – polyadenylation) ...
Section 12-3 RNA and Protein Synthesis
Section 12-3 RNA and Protein Synthesis

... c. It is the job of transfer RNA to bring the proper amino acid into the ribosome to be attached to the growing peptide chain. d. When the ribosome reaches a stop codon, it releases the newly formed polypeptide and the mRNA molecule. 18. What is an anticodon? ...
Transcription - OpenStax CNX
Transcription - OpenStax CNX

... template and liberate the newly made mRNA. Depending on the gene being transcribed, there are two kinds of termination signals, but both involve repeated nucleotide sequences in the DNA template that result in RNA polymerase stalling, leaving the DNA template, and freeing the mRNA transcript. On ter ...


... Ribosomal RNA gene transcripts are cleaved to yield rRNA molecules for ribosome assembly. The drug cordycepin blocks apperance of new mRNA in the cytoplasm, probably by blocking synthesis of poly-A terminal required for transport. Hemoglobin mRNA has a half-life of – 100 days; whereas, the average H ...
Name DNA, RNA and Protein Synthesis Test Review Study your
Name DNA, RNA and Protein Synthesis Test Review Study your

... G and C pair with each other. The RNA polymerase adds new nucleotides until it reaches the end of the gene where it stops. ...
Lecture 6, Exam III Worksheet Answers
Lecture 6, Exam III Worksheet Answers

... first one. 2. Missense mutation- usually causes only minimal damage. These usually change one amino acid into another amino acid; the new a.a. may have properties similar to the first or it may not affect the total protein structure. 3. Nonsense mutation- often lethal. This mutation changes a base p ...
I. Exam Section I Fundamental Cell Theory and Taxonomy (Chapter
I. Exam Section I Fundamental Cell Theory and Taxonomy (Chapter

... 2.Prevention of translation of damaged or unwanted RNA in the cytosol 3. Cell-Specific Regulation of Peptide and Protein Production a. Regulation of translation 1. 5’ and 3’ untranslated regions of mRNAs control their translation 2. Global regulation of translations by initiation factor phosphorylat ...
REPSA-Directed Identification of DNA
REPSA-Directed Identification of DNA

... Series of bases ≠ cellular function ...
Regulation of Gene Expression
Regulation of Gene Expression

... In the presence of lactose, lactose binds to the repressor causing it to change shape so DNA polymerase can easily bind to the promotor. ...
Gene Control of Cellular Activities
Gene Control of Cellular Activities

... ƒ Messenger RNA (mRNA) ƒ Carries DNA message from the DNA in the nucleus to the sites of protein synthesis in the cytoplasm ...
gene transcription and rna modification
gene transcription and rna modification

... transcription, as often as every 2 seconds in some bacteria. ...
Supporting Information S1: 1. Establishment of hSMP30 transcription
Supporting Information S1: 1. Establishment of hSMP30 transcription

... cooled to room temp and was reverse transcribed at 42ºC for 1hour using primer extension system (Promega, USA) according to manufacturer’s instruction. The same primer was used for the sequencing reactions of cloned SMP30 promoter containing exon 1. Sequencing reactions and primer extension product ...
The nucleus as an organized organelle
The nucleus as an organized organelle

... enhancers, and either increase (activation) or decrease (repression) the rate for assembly of a PIC (pre-initiation complex) on the promoter (TATA + initiator sequences) Enhancer ...
4.3 DNA Control Mechanisms
4.3 DNA Control Mechanisms

... DNA Control Mechanisms in all cells (Remember, these are ways to control Gene Expression.) A. Transposons “Jumping Genes” (These DNA segments act as “Blockers” to transcription.) 1. Barbara McClintock discovered this control mechanism in the1940’s. She worked with Maize. She won a Nobel Prize for th ...
Anaerobic Respiration - Deans Community High School
Anaerobic Respiration - Deans Community High School

... membrane and enters the ____________. Each triplet of bases on mRNA is called a __________. tRNA A second type of RNA is found in the cell’s cytoplasm. This is called ____________ _____ (______). Each molecule of tRNA has an exposed triplet of bases, known as an anticodon. This anticodon corresponds ...
Introduction and Review
Introduction and Review

... Nascent RNA strand synthesis (elongation) occurs only in the 5’  3’ direction, with new nucleotides added to the 3’ end of the nascent strand Transcription is catalyzed by DNA-directed RNA polymerases ...
Protein Synthesis
Protein Synthesis

... The Polypeptide chain is put together. Ribosome's moves along the chain and decodes the mRNA and attaches the amino acids together by peptide bonds. The tRNA will bring in the next amino acid, pair up with the codon on the mRNA and attach the next amino acid together ...
FAQ of Module 7
FAQ of Module 7

... (b) Shine-Dalgarno sequences: There is a specific sequence of bases on the mRNA, upstream of the start codon, that allows the ribosome to recognize and bind onto the start site to initiate the translation process. Such sequences are referred to as the Shine Dalgarno sequences. (c) Degeneracy of the ...
aa + aa + aa + aa aa – aa – aa – aa
aa + aa + aa + aa aa – aa – aa – aa

... Another ____________ molecule comes into place, bringing a second ____________________. ...
Lecture 7: Life`s Information Molecule II
Lecture 7: Life`s Information Molecule II

... • During transcription, one of the two DNA strands is copied into mRNA • During translation, the codons in the mRNA are read in the 5 to 3 direction • Each codon specifies the amino acid to be placed at the corresponding position along a polypeptide ...
Daily Trivia - James B. Conant High School
Daily Trivia - James B. Conant High School

... RNA is single stranded : DNA is double stranded RNA is made of the sugar Ribose – DNA is made of deoxyribose RNA has Uracil instead of Thymine – Both DNA and RNA have four nitrogen bases the difference is U vs T ...
Chapter 17: From Gene to Protein
Chapter 17: From Gene to Protein

... 13. Explain the significance of the reading frame during translation. 14. Explain the evolutionary significance of a nearly universal genetic code. The Synthesis and Processing of RNA 15. Explain how RNA polymerase recognizes where transcription should begin. Describe the promoter, the terminator, a ...
protein synthesis
protein synthesis

... mRNA READS: CAG UUC GUU CUA AUG Translation occurs ...
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RNA polymerase II holoenzyme

RNA polymerase II holoenzyme is a form of eukaryotic RNA polymerase II that is recruited to the promoters of protein-coding genes in living cells. It consists of RNA polymerase II, a subset of general transcription factors, and regulatory proteins known as SRB proteins.
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