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Cloze passage 4
Cloze passage 4

... p) Changes that occur spontaneously to DNA are called q) A type of radiation from the sun r) Environmental factors that induce mutations are known as ……………….. s) A type of mutation where some of the DNA is lost from the chromosome t) 2 English scientists who discovered the structure for DNA u) A fem ...
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... The coding region is the genetic information in the DNA that tells the specific structure (primary amino acid sequence) of the protein to be made. The aquaporin protein has a specific structure due to the primary amino acid sequence and the specific structure of a protein gives each protein a specif ...
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< 1 ... 322 323 324 325 326 327 328 329 330 ... 342 >

Transcriptional regulation

In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is transcribed. This control allows the cell or organism to respond to a variety of intra- and extracellular signals and thus mount a response. Some examples of this include producing the mRNA that encode enzymes to adapt to a change in a food source, producing the gene products involved in cell cycle specific activities, and producing the gene products responsible for cellular differentiation in higher eukaryotes.The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working in concert to finely tune the amount of RNA being produced through a variety of mechanisms. Prokaryotic organisms and eukaryotic organisms have very different strategies of accomplishing control over transcription, but some important features remain conserved between the two. Most importantly is the idea of combinatorial control, which is that any given gene is likely controlled by a specific combination of factors to control transcription. In a hypothetical example, the factors A and B might regulate a distinct set of genes from the combination of factors A and C. This combinatorial nature extends to complexes of far more than two proteins, and allows a very small subset (less than 10%) of the genome to control the transcriptional program of the entire cell.
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