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CHAPTER 17 FROM GENE TO PROTEIN Learning Objectives The
CHAPTER 17 FROM GENE TO PROTEIN Learning Objectives The

... 8. Explain the significance of the “reading frame” during translation. 9. Explain the evolutionary significance of a nearly universal genetic code. The Synthesis and Processing of RNA 10. Explain how RNA polymerase recognizes where transcription should begin. Describe the role of the promoter, the t ...
DNA Packaging - kyoussef-mci
DNA Packaging - kyoussef-mci

...  control of transcription by regulatory proteins (operon)  most of DNA codes for protein or RNA  no introns, small amount of non-coding DNA  regulatory sequences: promoters, operators ...
Regulation of Gene Expression - mvhs
Regulation of Gene Expression - mvhs

... • Lactose will only be digested for energy when there isn’t much glucose around • When glucose levels are low, level of cAMP molecule builds up ...
Gene Expression
Gene Expression

... Genetic Code: After transcription the _______ material message is ready to be translated from the _________________ of RNA to the language of proteins. The instructions for building a protein are written as a series of _______ nucleotide sequences called __________. 2. Translation 2nd step: The prot ...
The Central Dogma of Genetics
The Central Dogma of Genetics

... instructions (coded in DNA) from the nucleus into the cytoplasm. mRNA molecules are often called transcripts. • Ribosomal RNA (rRNA) – a structural component of ribosomes (the complexes that are involved in assembling proteins based upon information in mRNA templates) • Transfer RNA (tRNA) – acts as ...
Gene Expression/Mutations
Gene Expression/Mutations

... allows processed mRNA to leave and go to cytoplasm to ribosome to make protein ...
6-Premedical-From-Gene-to
6-Premedical-From-Gene-to

... 61 of 64 triplets code for 20 amino acids. There is redundancy, and it is not random. Codons for the same amino acids differ in third base of triplet. ...
T T PowerPoint
T T PowerPoint

... • The phenotype is the organism’s specific traits (or what it looks like and how it functions), which arise from the actions of a wide variety of proteins. ...
Transcription and Translation
Transcription and Translation

... Remember: MR CATAP (mRNA, ribosome, codon, anticodon, tRNA, amino acid, polypeptide) • mRNA binds to a ribosome which initiates translation • The mRNA is read in codons (from start codon = AUG) • Anticodons on tRNA align opposite appropriate codons ...
Transcription Regulation
Transcription Regulation

... • Computational approaches were used to identify potential binding sites. • Only 2-35% of found binding sites exactly match consensus sequences. ...
Section 5-4
Section 5-4

... Section 5-4 Genes, DNA, and Proteins ...
Lecture 6, Exam III Worksheet Answers
Lecture 6, Exam III Worksheet Answers

... (CAP). CAP is only active whenever cAMP is bound to it. What do they bind to together? After cAMP binds to the CAP, they travel together to the promoter where they signal for the RNA polymerase to come in and start transcription. What response does this illicit? The start of transcription and the ma ...
Promoter Regions
Promoter Regions

... Consensus Sequence: Sigma factor binding regions in the promoter region. The term consensus sequence refers to the sequence not being the same for every promoter. The given consensus sequences are based on base pairs with the highest occurrence. In E. Coli, the consensus sequences are found at -10 a ...
lacI
lacI

... In bacterial RNA polymerse, the core enzyme consists of four subunits: two copies of alpha (α), a single copy of beta (β), and a single copy of ...
Slide 1
Slide 1

... ...
Chapter 19 - Control of Gene Expression
Chapter 19 - Control of Gene Expression

... mitosis. When viewed under a microscope, the many chromatids look like a giant chromosome. The large number of chromatids allows the cell to produce more mRNA and therefore more gene product (protein). Developmental stages in the larva are associated with the appearance of chromosomal puffs. These a ...
How do proteins recognize DNA
How do proteins recognize DNA

... 3)  Transfer RNAs (tRNA) are RNAs that become covalently linked to amino acids (activating the amino acids). tRNAs contain anti-codons that interact with condons on mRNAs. tRNAs transfer amino acids to a nascent polypeptide chain in the ribosome. The covalent linkage between a given amino acid and t ...
transcription and rna
transcription and rna

...  factor (fifth subunit) Holoenzyme binds to promoter Initiates transcription  factor releases from core enzyme during transcription Transcription in Eukaryotes Eukaryotic polymerases Three different RNA polymerases Ten or more subunits Regulatory elements Eukaryotic promoters bind transcription fa ...
Mock Exam 2BY330 Summer 2014 Assume that 4 molecules of
Mock Exam 2BY330 Summer 2014 Assume that 4 molecules of

... 9. Describe the “9 + 2 arrangement” of microtubules. In what two structures can this arrangement be found? ...
7.2.7 Describe the promoter as an example of non
7.2.7 Describe the promoter as an example of non

... • Only some DNA sequences code for synthesis of polypeptides (single-copy genes) • Non-coding regions (highly-repetitive sequences) have other functions:  tRNA production  rRNA production (ribosomal RNA)  Control gene expression Enhancers: regulatory sequences on DNA which increase the rate of tr ...
The Molecular Genetics of Gene Expression
The Molecular Genetics of Gene Expression

... Transcription Initiation • Promoter = nucleotide sequence 20-200 bp long—is the initial binding site of RNA polymerase and transcription initiation factors ...
here - VCU
here - VCU

... humans), a gene's exons are separated by long regions of DNA (called introns or sometimes "junk DNA") that have no apparent function. The DNA that makes up the human genome can be subdivided into information bytes called genes. Each gene encodes a unique protein that performs a specialized function ...
protein synthesis (simplified)
protein synthesis (simplified)

... It is the Sequence of bases that act like a code The sequence (order) of bases tells the cell what proteins to make. The sequence of bases dictates the sequence of amino acids, which determines the shape of a protein. ...
Transcriptional regulatory roles of G
Transcriptional regulatory roles of G

... G-quadruplexes (G4s) are four-stranded DNA secondary structures involved in a diverse range of biological processes. Although the anti-cancer potential of G4s in oncogene promoters has been extensively investigated, the functions of promoter G4s in non-cancer-related genes are not known. We have exp ...
Transcription
Transcription

... Introns typically begin with 5’-GU, and end with AG3’, but more than just these sequences is needed to specify a junction between exon and intron. The removal of the introns is called RNA splicing and it involves a complex called spliceosomes. A spliceosome consists of the preRNA and a group of prot ...
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Transcriptional regulation

In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is transcribed. This control allows the cell or organism to respond to a variety of intra- and extracellular signals and thus mount a response. Some examples of this include producing the mRNA that encode enzymes to adapt to a change in a food source, producing the gene products involved in cell cycle specific activities, and producing the gene products responsible for cellular differentiation in higher eukaryotes.The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working in concert to finely tune the amount of RNA being produced through a variety of mechanisms. Prokaryotic organisms and eukaryotic organisms have very different strategies of accomplishing control over transcription, but some important features remain conserved between the two. Most importantly is the idea of combinatorial control, which is that any given gene is likely controlled by a specific combination of factors to control transcription. In a hypothetical example, the factors A and B might regulate a distinct set of genes from the combination of factors A and C. This combinatorial nature extends to complexes of far more than two proteins, and allows a very small subset (less than 10%) of the genome to control the transcriptional program of the entire cell.
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