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Sten_Ilmjärv_Different Aspects of Gene Regulation
Sten_Ilmjärv_Different Aspects of Gene Regulation

... cells don’t have a nucleus, the mRNA can be translated at the same time as transcription. In eukaryotic cell this is impossible, since translation is outside of nucleus and the mRNA has to be ready for it to go to cytoplasm. The translation is said to be polyribosomal when there is more than one act ...
Transcription and Translation
Transcription and Translation

... 3.5.5 One Gene – One Polypeptide Theory One gene is transcribed and translated to produce one polypeptide. Some protein are composed of a number of polypeptides and in this theory each polypeptide has its own gene. ...
READ: Protein Synthesis File
READ: Protein Synthesis File

... helix. Regulatory proteins and small RNAs interact with non-coding sequences within the DNA to direct the conformational changes as well as the binding of helicases and transcription factors. Other non-coding DNA sequences called enhancers are not necessary for transcription, but their presence upst ...
Matching review Connect with lines
Matching review Connect with lines

... Animalia Fungi ...
pNZ:vig Vector information: IRES
pNZ:vig Vector information: IRES

... The foreign DNA inserts are introduced into lactococcal vector in this manner; eukaryotic promoter, followed by the VP2 gene (coding for VP2 protein from infectious bursal disease virus, the first gene to be transcribed by the promoter), IRES, gfp gene (gene encoding for green fluorescent protein, t ...
Translation - CS
Translation - CS

... are polypeptides of 70-3000 amino-acids ...
DNA Notes Day 2 PowerPoint
DNA Notes Day 2 PowerPoint

... Steps for Replication 1. DNA helicase unzips the DNA by breaking the hydrogen bonds holding the bases together 2. The two strands unwind creating a replication fork. 3. Each strand serves as a template so the correct pair can come in and bind to the strands 4. DNA polymerase joins the nucleotides ...
Negative regulation
Negative regulation

... •Not all expressed at any one time •May need very high levels e.g. translation elongation factors •May need very low levels e.g. some DNA repair enzymes •Expression needs to vary with time and cell type - otherwise every cell would be the same and there would be no organisms except microbes ...
III Transcriptional Regulation
III Transcriptional Regulation

... the mRNA and subsequent gene expression. Transcript instability permits a cell to adapt its pattern of gene expression continuously to changing physiological needs, and therefore providing a cell with flexibility in effecting rapid change. Very stable transcripts are optimal for achieving high expre ...
Eukaryotic Genomes - Building Directory
Eukaryotic Genomes - Building Directory

... All cells in an organism contain an identical genome (set of genes) However, the genes expressed in the cells of each type are unique Most of the DNA in eukaryotic genomes are noncoding – unsure of its purpose  25,000 genes in humans  Only about 1.5% codes for protein The expression of specific ge ...
Cell Parts: Protein Synthesis
Cell Parts: Protein Synthesis

... Catalyst: “Remembering 9/11” ...
Chapter 11 from book
Chapter 11 from book

... concentration becomes excessive ...
Terminator
Terminator

... Types of RNA • All three types of RNA are transcribed from DNA – Messenger RNA – carries the coded message from the DNA to the ribosome in the cytoplasm – Ribosomal RNA – reads the mRNA – Transfer RNA – transfers the correct amino acid to the ribosome ...
PROTEIN SYNTHESIS What is a gene?
PROTEIN SYNTHESIS What is a gene?

... Types of RNA • All three types of RNA are transcribed from DNA – Messenger RNA – carries the coded message from the DNA to the ribosome in the cytoplasm – Ribosomal RNA – reads the mRNA – Transfer RNA – transfers the correct amino acid to the ribosome ...
sg 10
sg 10

... 24. Distinguish between a point mutation and a frameshift mutation. Which would be more severe? ...
AP Biology
AP Biology

... 24. Distinguish between a point mutation and a frameshift mutation. Which would be more severe? ...
5.3 Presentation: Protein Synthesis
5.3 Presentation: Protein Synthesis

... amounts of proteins • The cell produces proteins that are structural (forms part of cell materials) or functional (enzymes and hormones). • All of an organisms cells have the same DNA, but the cells differ on the expression of the genes. • Each individual in a sexually reproducing population has sli ...
Gene Regulation Section 12–5
Gene Regulation Section 12–5

... The actions of DNA-binding proteins help to determine whether a gene is turned on ...
Lecture 7
Lecture 7

... • Purpose is to create new DNA strand, so that upon binary fission, each of the 2 cells receives a complete copy of DNA • Bidirectional- from distinct starting pointproceeds in both directions • Semi- conservative- each of the 2 DNA helix’s generated contains 1 new strand and 1 old strand ...
control of gene expression
control of gene expression

... eukaryotes • This is much more complicated due to the numbers and arrangement of genes within the genome • Several genes may be responsible for one characteristic, and while they may be clustered together, the mechanisms that control them may be located on different chromosomes ...
Molecular Biology Primer
Molecular Biology Primer

... same frequency P = (1/4)n, where n is the string’s length • Promoter sequences – Sequences recognized by RNA polymerases as being associated with a gene ...
overview rna, transcription, translation
overview rna, transcription, translation

... itself to leave the nucleus, enzymes cut out and remove the introns. The remaining exons are spliced back together again by a different enzyme. This modified m RNA is what comes to the ribosome to be translated into polypeptides. ...
没有幻灯片标题
没有幻灯片标题

... 20.3 Promoter elements are defined by mutations and footprinting 20.4 RNA polymerase I has a bipartite promoter 20.5 RNA polymerase III uses both downstream and upstream promoters 20.6 The startpoint for RNA polymerase II 20.7 TBP is a universal factor 20.8 TBP binds DNA in an unusual way 20.9 The b ...
Comparative Genomics
Comparative Genomics

... Promoters: a number of adjacent genes are transcribed simultaneously. These genes were shown to share a promoter, much like prokaryotes control gene expression. ...
Controllable genes
Controllable genes

... c. Physiologically, the CNS (central nervous system) is responsible for key steps in male courtship behavior.) (fruitless) The sex-specific fru mRNAs are synthesized in only a few neurons in the CNS (500/100,000). The proteins encoded by these mRNAs regulate transcription of a set of specific genes, ...
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Transcriptional regulation

In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is transcribed. This control allows the cell or organism to respond to a variety of intra- and extracellular signals and thus mount a response. Some examples of this include producing the mRNA that encode enzymes to adapt to a change in a food source, producing the gene products involved in cell cycle specific activities, and producing the gene products responsible for cellular differentiation in higher eukaryotes.The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working in concert to finely tune the amount of RNA being produced through a variety of mechanisms. Prokaryotic organisms and eukaryotic organisms have very different strategies of accomplishing control over transcription, but some important features remain conserved between the two. Most importantly is the idea of combinatorial control, which is that any given gene is likely controlled by a specific combination of factors to control transcription. In a hypothetical example, the factors A and B might regulate a distinct set of genes from the combination of factors A and C. This combinatorial nature extends to complexes of far more than two proteins, and allows a very small subset (less than 10%) of the genome to control the transcriptional program of the entire cell.
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