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Organic Chemistry, 11th Edition
Organic Chemistry, 11th Edition

... COVER IMAGE © Gerhard Schulz/Age Fotostock America, Inc.  ...
Silica supported zinc chloride catalyzed acetylation of amines
Silica supported zinc chloride catalyzed acetylation of amines

... revealed that the application of inorganic solids especially zeolites have recently received considerable attention due to their unique physical and chemical properties. H-FER20 has been reported for the acetylation of alcohols and phenols under solventfree conditions. However, some of these acetyla ...
Bimolecular reactions of the chromium
Bimolecular reactions of the chromium

... The study of the gas-phase reactions of bare transition-metal cations with organic substrates during the last few years has given a wealth.of information about organometallic chemistry.’ A typical gas-phase reaction of a transition-metal ion with a hydrocarbon is the oxidative insertion into C-H and ...
CYCLOALKANES, POLYMERS, ALCOHOLS AND ETHERS
CYCLOALKANES, POLYMERS, ALCOHOLS AND ETHERS

... The boiling point of ethyl alcohol is much higher than that of dimethyl ether, though both have same molecular mass. The reason for this is : a) Ether is insoluble in water b) Methyl group is present in ether c) Ethyl alcohol has hydrogen bonding d) The hydrogen of the O-H group is electronegative ...
Required Resources and Materials
Required Resources and Materials

...  As a group, they will build models of organic reactions and their products, by picking up package and following instructions and using included model  They will also write down the equation on a paper.  When time ends, the researchers will go to another reaction and learn what took place, while ...
45.1 Inter-conversions between the functional groups
45.1 Inter-conversions between the functional groups

... heating a mixture of ethanoic acid and ethanol in the presence of an acid catalyst. The process is known as esterification. ...
R - MSU Chemistry
R - MSU Chemistry

... stable   enolate   and   NaOMe   is   quite   strong   enough   to   convert   the   diketone   entirely   into   the   enolate.   The   problem   is   the   acylation   step.   With  a  sodium  enolate  and  a  reactive  acylating  agent ...
69. A general approach to the enantioselective -oxidation of aldehydes via synergistic catalysis
69. A general approach to the enantioselective -oxidation of aldehydes via synergistic catalysis

... (entries 4 and 8), while the incorporation of unsaturation in the form of olefins and aromatic rings is not detrimental to the process (entries 1–2, 5, 7, and 13–14). Notably, significant variation in steric environment on the aldehyde component is readily accommodated, with the more demanding frame ...
Lecture (8)
Lecture (8)

... 6-Chemical properties of alcohols: The chemical properties of an alcohol are determined by its functional group, the hydroxyl group reactions of an alcohol can involve the breaking of either of two bonds, C─OH bond, with removal of the (OH) group or the (O-H) bond with removal of (-H).Either kind of ...
proline catalyzed direct asymmetric aldol and mannich reactions
proline catalyzed direct asymmetric aldol and mannich reactions

... revealed no appreciably better catalysts. Direct proline catalysis was considered to be particularly favorable because, as the authors noted, the reactions have several advantages over normal enolate Copyright © 2005 by Mirth Hoyt ...
Cerium(IV) Ammonium Nitrate as a Catalyst in
Cerium(IV) Ammonium Nitrate as a Catalyst in

... (c) The third is Lewis acid catalysis. In this connection, it is interesting to note that CAN may be a useful alternative to the expensive, hygroscopic lanthanide triflates. It is also relevant to mention that, among lanthanides, Ce salts are the ones that have the lowest affinity for oxygen, making ...
Aldehydes and Ketones
Aldehydes and Ketones

... and Ketones • Treatment of an aldehyde or ketone with either an organolithium or Grignard reagent followed by water forms an alcohol with a new carbon–carbon bond. • This reaction is an addition because the elements of R’’ and H are added across the π bond. ...
Copper-Catalyzed Hydroalkylation of Terminal Alkynes
Copper-Catalyzed Hydroalkylation of Terminal Alkynes

... During the development of the hydroalkylation reaction we made several observations. The choice of catalyst is crucial for the success of the reaction. SIPr- and IPrCuOTf catalyze the desired reaction efficiently (Table 1, entries 1 and 2), while other NHC ligands that are similar to SIPr electronical ...
Organic Chemistry - Madison Public Schools
Organic Chemistry - Madison Public Schools

... • Carbon can also form ringed structures. • Five- and six-membered rings are most stable.  Can take on conformation in which angles are very close to tetrahedral angle.  Smaller rings are quite strained. ...
View/Open
View/Open

... © 2008 Thomson Learning, Inc. All Rights Reserved. Thomson Learning WebTutorTM is a trademark of Thomson Learning, Inc. Library of Congress Control Number: 2006938700 ...
Aldehydes and Ketones
Aldehydes and Ketones

... The carbonyl carbon of an aldehyde is more accessible to the nucleophile. Ketones have greater steric crowding in their transition states, so they have less stable transition states. ...
Aldehydes and Ketones
Aldehydes and Ketones

... The carbonyl carbon of an aldehyde is more accessible to the nucleophile. Ketones have greater steric crowding in their transition states, so they have less stable transition states. ...
Synthesis of Alcohols Using Grignard Reagents Grignard reagents
Synthesis of Alcohols Using Grignard Reagents Grignard reagents

... (CH3)2CHCCH CHCCH3 CH3 ...
Alcohols and Phenols
Alcohols and Phenols

... • Use “phene” (the French name for benzene) as the parent hydrocarbon name, not benzene • Name substituents on aromatic ring by their position from OH ...
DEVELOPMENT OF GREEN AND OF POLYMER
DEVELOPMENT OF GREEN AND OF POLYMER

... copper chromite being the most commonly used. Reactions can be carried out in the gas phase or in the liquid phase. Aliphatic alcohols with three to eight carbons are converted to aldehydes using copper chromite on Celite at 300-350 ºC. Quantitative yields can be obtained when reactions are carried ...
Bronsted acidic ionic liquid as an efficient and reusable catalyst for
Bronsted acidic ionic liquid as an efficient and reusable catalyst for

... Transesterification of b-ketoesters is one of the important reaction for the synthesis of esters and have variety of applications in pharmaceutical, agrochemical, chemical and polymer industries [1,2]. Transesterification is an equilibrium process and several methods have been reported for the transes ...
Alcohols and Phenols
Alcohols and Phenols

... • Use “phene” (the French name for benzene) as the parent hydrocarbon name, not benzene • Name substituents on aromatic ring by their position from OH ...
Aldehydes and Ketones
Aldehydes and Ketones

... NAMING ALDEHYDES • ALDEHYDES ARE NAMED BY REPLACING THE FINAL “E” OF THE NAME OF THE ALKANE WITH THE SAME NUMBER OF CARBONS TO “AL”. • BECAUSE IN ALDEHYDES THE CARBONYL GROUP IS ALWAYS ATTACHED TO THE FIRST CARBON, THERE IS NO NEED TO PLACE A 1 IN FRONT OF THE NAME. • IF THERE ARE SUBSTITUENTS PRES ...
Chapter 21 aldehydes and ketones
Chapter 21 aldehydes and ketones

... Apply all of the usual rules of nomenclature. With cyclic ketones, numbering always begins at the carbonyl carbon, but the “1” is usually omitted from the name. The ring is then numbered clockwise or counterclockwise to give the first substituent the lower number. ...
Chem 30CL-Lecture 12.. - UCLA Chemistry and Biochemistry
Chem 30CL-Lecture 12.. - UCLA Chemistry and Biochemistry

... -OH (pKa~16-18), -NHx (pKa~35), -SH (pKa~9-12), -COOH (pKa~3-5)  Some functional groups react with the reagent because they contain electrophilic atoms: -CHO, -COR, -CONR2, -COOR, -C≡N, -NO2, -SO2R, epoxides (ring opening)  If more than one of these groups is present, groups that are ...
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Elias James Corey



Elias James ""E.J."" Corey (born July 12, 1928) is an American organic chemist. In 1990, he won the Nobel Prize in Chemistry ""for his development of the theory and methodology of organic synthesis"", specifically retrosynthetic analysis. Regarded by many as one of the greatest living chemists, he has developed numerous synthetic reagents, methodologies and total syntheses and has advanced the science of organic synthesis considerably.
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