Rxns of Alkynes
... 1. name like alkenes, but no cis/trans or E/Z 2. find longest chain containing funct. grp and # so funct grp # smallest 3. if 2 triple bonds, diyne a. if 3 trple bonds, triyne b. if 4, tetrayne, then pentayne, hexayne, heptayne, etc 4. with number (#) as prefix a. funct grp has priority with numberi ...
... 1. name like alkenes, but no cis/trans or E/Z 2. find longest chain containing funct. grp and # so funct grp # smallest 3. if 2 triple bonds, diyne a. if 3 trple bonds, triyne b. if 4, tetrayne, then pentayne, hexayne, heptayne, etc 4. with number (#) as prefix a. funct grp has priority with numberi ...
COUPLING REACTIONS IN ORGANIC SYNTHESIS
... The addition of dihydrogen to Vaska's complex and other transition metals is a reversible reaction. The hydrogen can be released again if the reaction moves to the left in a reductive elimination. That reversibility makes transition metal compounds useful for hydrogen storage. Hydrogen gas is volumi ...
... The addition of dihydrogen to Vaska's complex and other transition metals is a reversible reaction. The hydrogen can be released again if the reaction moves to the left in a reductive elimination. That reversibility makes transition metal compounds useful for hydrogen storage. Hydrogen gas is volumi ...
Synthesis, Crystal-Structure Determination and Magnetic Properties
... results in the bare metals or metal nitrides; CuNCN, for example, decays at 250 °C already. A synthesis following the CuNCN route, on the other hand, is impossible for CoNCN and NiNCN because precursors similar to Cu4(NCN)2NH3 containing a monovalent Co+ or Ni+ do not exist. In this contribution we ...
... results in the bare metals or metal nitrides; CuNCN, for example, decays at 250 °C already. A synthesis following the CuNCN route, on the other hand, is impossible for CoNCN and NiNCN because precursors similar to Cu4(NCN)2NH3 containing a monovalent Co+ or Ni+ do not exist. In this contribution we ...
Slides
... amines to form enamines l Cyclic amines are often used l The reaction is catalyzed by acid l Removal of water drives enamine formation to completion ...
... amines to form enamines l Cyclic amines are often used l The reaction is catalyzed by acid l Removal of water drives enamine formation to completion ...
The 9-Phenyl-9-fluorenyl Group for Nitrogen Protection in
... protect the α-center. For example in the case of esters, this could be further explained as follows: the most favorable conformation for deprotonation is one in which the α-hydrogen-carbon bond lies in a plane orthogonal to the plane of the carbonyl system, allowing for maximum orbital overlap as th ...
... protect the α-center. For example in the case of esters, this could be further explained as follows: the most favorable conformation for deprotonation is one in which the α-hydrogen-carbon bond lies in a plane orthogonal to the plane of the carbonyl system, allowing for maximum orbital overlap as th ...
Theoretical Competition - Austrian Chemistry Olympiad
... In order to gain information about the kinetics of this reaction, it is possible to titrate S2O32- with iodine solution from time to time. The following procedure is convenient. 2.00 mL of the thiosulphate solution, which is used in the experiment, need 12.2 mL of iodine solution with c = 5.00·10-3 ...
... In order to gain information about the kinetics of this reaction, it is possible to titrate S2O32- with iodine solution from time to time. The following procedure is convenient. 2.00 mL of the thiosulphate solution, which is used in the experiment, need 12.2 mL of iodine solution with c = 5.00·10-3 ...
Amide Uses
... indigo, hydrazine, and sodium cyanide. It is the reagent of choice for the drying of ammonia (liquid or gaseous) and is also widely used as a strong base in organic chemistry, often in liquid ammonia solution. One of the main advantages to the use of sodamide is that it is an excellent base and rare ...
... indigo, hydrazine, and sodium cyanide. It is the reagent of choice for the drying of ammonia (liquid or gaseous) and is also widely used as a strong base in organic chemistry, often in liquid ammonia solution. One of the main advantages to the use of sodamide is that it is an excellent base and rare ...
Chapter 9 Stoichiometry
... produced based on the limiting reactant. If everything in the reaction went according to plan, and all of the reactant(s) reacted, this is how much product should be made. This is NOT the same as the actual yield- amount that is produced based on an experiment Error occurs, so actual yield is ...
... produced based on the limiting reactant. If everything in the reaction went according to plan, and all of the reactant(s) reacted, this is how much product should be made. This is NOT the same as the actual yield- amount that is produced based on an experiment Error occurs, so actual yield is ...
Porous silicon-based nanostructured microparticles as degradable
... 1.98 (2H, q, CH2=CHCH2), 1.36-1.11 (14H, m, alkyl-H and 2H, broad s, NH2). 13C NMR (75 MHz, CDCl3): 139.2, 114.1, 42.3, 33.9, 33.8, 29.6, 29.5 (2 overlapping signals), 29.2, 29.0 and 26.9. ESI-MS: predicted C11H23N+ (MH+) m/z = 169.183. Found m/z = 169.190. ...
... 1.98 (2H, q, CH2=CHCH2), 1.36-1.11 (14H, m, alkyl-H and 2H, broad s, NH2). 13C NMR (75 MHz, CDCl3): 139.2, 114.1, 42.3, 33.9, 33.8, 29.6, 29.5 (2 overlapping signals), 29.2, 29.0 and 26.9. ESI-MS: predicted C11H23N+ (MH+) m/z = 169.183. Found m/z = 169.190. ...
Ahmed Fazary_Click Chemistry
... Click Chemistry is a general term that identifies a class of chemical transformations with a number of attaractive features including excellent functional-group tolerance, high yields and good selectivity under mild experimental conditions. As defined by K. B. Sharpless – “‘Click’ chemistry…a set of ...
... Click Chemistry is a general term that identifies a class of chemical transformations with a number of attaractive features including excellent functional-group tolerance, high yields and good selectivity under mild experimental conditions. As defined by K. B. Sharpless – “‘Click’ chemistry…a set of ...
2-3 Carbon Compounds: Organic Biomolecules
... What does “poly” mean? – many So What is a monomer? – One piece is a monomer…. like a lego block What is a polymer? – Add many of those pieces together and you get a polymer!…like a finished ...
... What does “poly” mean? – many So What is a monomer? – One piece is a monomer…. like a lego block What is a polymer? – Add many of those pieces together and you get a polymer!…like a finished ...
I (21 points) Complete the following reactions by providing starting
... A. (JOC 2008, ASAP, Hartung) The reagent 2-chloro-bis[menth-1-yloxycarbonyl]-1,3,2dioxaphospholane was shown to be useful in determining the enatiomeric purity of chiral alcohols via 31P NMR. The enatiomerically pure phosphorous reagent reacts with chiral alcohols to form diasteromers as shown below ...
... A. (JOC 2008, ASAP, Hartung) The reagent 2-chloro-bis[menth-1-yloxycarbonyl]-1,3,2dioxaphospholane was shown to be useful in determining the enatiomeric purity of chiral alcohols via 31P NMR. The enatiomerically pure phosphorous reagent reacts with chiral alcohols to form diasteromers as shown below ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
... 5. Explain the change in the geometry of excited state molecule in a photochemical process and the variation in its physical property. 6. What is Norrish type I and II cleavage reactions? Give suitable examples. 7. What are the important guidelines to be followed while choosing alternate synthetic r ...
... 5. Explain the change in the geometry of excited state molecule in a photochemical process and the variation in its physical property. 6. What is Norrish type I and II cleavage reactions? Give suitable examples. 7. What are the important guidelines to be followed while choosing alternate synthetic r ...
Name - Clark College
... Please work and place your answers in the spaces provided. Show your work for maximum credit! The last page may be torn off and used for scratch paper. Do not write on the IR/NMR sheet. Bring all material up when you are finished. 1. Provide the reagents for the following 2-step transformation. [6] ...
... Please work and place your answers in the spaces provided. Show your work for maximum credit! The last page may be torn off and used for scratch paper. Do not write on the IR/NMR sheet. Bring all material up when you are finished. 1. Provide the reagents for the following 2-step transformation. [6] ...
1072. A General Synthesis of Ethers.
... of the reaction mixtures was carried out with a,n Aerograph dual-column temperature-programming gas chromatograph, model A-350-B, from Wilkens Instrument & Research, Inc., Berkely, Calif. The columns (3 m.) were filled with Chromosorb W coated with 15% of Silicone oil 550 or Apiezon L. Analysis was ...
... of the reaction mixtures was carried out with a,n Aerograph dual-column temperature-programming gas chromatograph, model A-350-B, from Wilkens Instrument & Research, Inc., Berkely, Calif. The columns (3 m.) were filled with Chromosorb W coated with 15% of Silicone oil 550 or Apiezon L. Analysis was ...
Faculteit der Natuurwetenschappen, Wiskunde en Informatica
... to good diasteromeric ratios. However separation proved to be difficult. Five addition products (2a-2e) with a chiral acetal are synthesized via diastereoselective addition of Grignard reagents to β-aldehyde acetals. Different diastereomeric ratios are obtained; from 55:45 to 93:7. It should be note ...
... to good diasteromeric ratios. However separation proved to be difficult. Five addition products (2a-2e) with a chiral acetal are synthesized via diastereoselective addition of Grignard reagents to β-aldehyde acetals. Different diastereomeric ratios are obtained; from 55:45 to 93:7. It should be note ...
Please don`t do problem 31a, but please do problem 32c
... Also self aldol product of acetaldehyde and propionaldehyde ...
... Also self aldol product of acetaldehyde and propionaldehyde ...
Production of synthesis gas
... First , in the Air separation section the oxygen are produced with 99.5 vol% purity . Second , in the soot recovery and recycle section the Naphtha stripper recycle are produced which is fed to oxidizer reactor . Third, in the partial oxidation and heat recovery section the vacuum feedstock's is fe ...
... First , in the Air separation section the oxygen are produced with 99.5 vol% purity . Second , in the soot recovery and recycle section the Naphtha stripper recycle are produced which is fed to oxidizer reactor . Third, in the partial oxidation and heat recovery section the vacuum feedstock's is fe ...
Discodermolide
(+)-Discodermolide is a polyketide natural product found to stabilize microtubule. (+)-discodermolide was isolated by Gunasekera and his co-workers at the Harbor Branch Oceanographic Institute from the deep-sea sponge Discodermia dissoluta in 1990. (+)-Discodermolide was found to be a potent inhibitor of tumor cell growth in several MDR cancer cell lines. (+)-discodermolide also shows some unique characters, including a linear backbone structure, immunosuppressive properties both in vitro and in vivo, potent induction of an accelerated senescence phenotype, and synergistic antiproliferative activity in combination with paclitaxel. Discodermolide was recognized as one of the most potent natural promoters of tubulin assembly. A large number of efforts toward the total synthesis of (+)-discodermolide were directed by its interesting biological activities and extreme scarcity of natural sources (0.002% w/w from frozen marine sponge). The compound supply necessary for complete clinical trials cannot be met by harvesting, isolation, and purification. As of 2005, attempts at synthesis or semi-synthesis by fermentation have proven unsuccessful. As a result, all discodermolide used in preclinical studies and clinical trials has come from large-scale total synthesis.