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Neurological characterization of mice deficient in GSK3α highlight
Neurological characterization of mice deficient in GSK3α highlight

... for normal Mendelian transmission. Continued breeding yielded offspring that consistently carried only the recombined GSK3α alleles without the Cre-recombinase, confirming that we had produced a mouse strain that lacked active GSK3α genes completely (Figure 1A). We hereby confirmed independently, th ...
Section Summary
Section Summary

... Physiological Regulatory Mechanisms: Drinking Two Types of Thirst • Our bodies lose water continuously, primarily through evaporation. • Each breath exposes the moist inner surfaces of the respiratory system to the air; thus, each breath causes the loss of a small amount of water. • In addition, ou ...
Spatial cognition, body representation and affective processes
Spatial cognition, body representation and affective processes

... constancy or postural control. In this review article we point out three emerging streams of research highlighting the importance of vestibular input: (1) Spatial Cognition: Modulation of vestibular signals can induce specific changes in spatial cognitive tasks like mental imagery and the processing ...
Test Bank 1
Test Bank 1

... Correct: The fact that there is a negative charge caused by unequal amounts of positive and negative ions is called a state of polarization. c. equilibrium d. depolarization Incorrect: Depolarization refers to a state where the electrical potential of a cell changes, either from a positive to a nega ...
Electroencephalography - Department of Computational and
Electroencephalography - Department of Computational and

... system[10] for most clinical and research applications (except when high-density arrays are used). This system ensures that the naming of electrodes is consistent across laboratories. In most clinical applications, 19 recording electrodes (plus ground and system reference) are used. A smaller number ...
Insula function in anorexia nervosa
Insula function in anorexia nervosa

... will give more insights in the neurocircuitry in which the insula plays a crucial role and can therefore be used to investigated neural disorders so ultimately better treatments can be developed. The insula was first described by J.C. Reil, a German anatomist, in 180910. The insula is also known as ...
B-Lymphocyte-Mediated Delayed Cognitive Impairment following
B-Lymphocyte-Mediated Delayed Cognitive Impairment following

... stroke are at increased risk of developing dementia, and approximately one-third will eventually suffer from vascular dementia (Barba et al., 2000; Leys et al., 2005; Béjot et al., 2011). In many of these patients, dementia might be caused by an associated comorbidity, but even after controlling fo ...
Serotonin synthesis, release and reuptake in terminals: a
Serotonin synthesis, release and reuptake in terminals: a

... Even this brief discussion shows why understanding the casual mechanisms in serotonergic signaling is a challenging problem. Not only does one have to understand mechanism and function on four different levels, genomic, biochemical, electrophysiological, and behavioral, but changes on each level aff ...
Increased Anxiety 3 Months after Brief Exposure to MDMA
Increased Anxiety 3 Months after Brief Exposure to MDMA

... subjected to some recent criticism (Kish, 2002). Nonetheless, there is growing clinical evidence that human MDMA users, particularly heavy users, are more prone to a variety of psychological problems, including anxiety, depression, and memory impairment (Morgan, 2000; Parrott, 2001; Schifano et al, ...
Reuss 9..48
Reuss 9..48

... it should be noted that a number of methodical parameters render it difficult to draw final conclusions on certain aspects of SCN morphology. For example, day-night differences in the expression of neuroactive substances may not or only inadequately be detected when respective changes were out of ph ...
Explaining The Efficiency Of Marte Meo From A Neurobiological
Explaining The Efficiency Of Marte Meo From A Neurobiological

... But how can the efficiency of Marte Meo be explained from a neurobiological perspective? (1) ...
Author`s personal copy - Laboratoire de Neurosciences Cognitives
Author`s personal copy - Laboratoire de Neurosciences Cognitives

... segment of the globus pallidus (GPi). The anatomo-physiological organization of the BG and their output suggested that interfering with such hyper-activity could restore motor function and improve parkinsonism. Several animal models in rodents and primates, as well as clinical studies and neurosurgi ...
Serotonin Modulates Developmental Microglia
Serotonin Modulates Developmental Microglia

... everywhere in the brain and at various ages (data not shown). For the quantitative analysis, we focused on dLGN in the thalamus, in which axons from RGCs form synaptic connections with relay neurons in order to establish the retinogeniculate pathway of the visual system. We selected this region of i ...
Chronic Use and Cognitive Functioning and Mental Health
Chronic Use and Cognitive Functioning and Mental Health

... Studies of attentional deficits among individuals who use cannabis chronically have also yielded mixed results. Specifically, an fMRI study that compared those who use cannabis chronically to controls during a visual-attention task showed no differences in task performance. However, individuals who ...
Effects of Fructose vs Glucose on Regional
Effects of Fructose vs Glucose on Regional

... associated with fructose- and glucosemediated changes in animal feeding behaviors translates to humans is not completely understood. New technologies are available to facilitate translation of animal to human studies. Functional magnetic resonance imaging (fMRI) provides a noninvasive way to assess ...
1 - TEST BANK 360
1 - TEST BANK 360

... Bloom’s Taxonomy: Knowledge Difficulty: Difficult APA Goal: Outcome 1.2 17. You cannot fire a gun softly, or flush a toilet halfway. Like an action potential, gun fire and a toilet’s flush follow the __________ law. a. on-or-off b. graded action c. all-or-none d. binary response Answer: c Page: 52 B ...
Preview Sample 3
Preview Sample 3

... Bloom’s Taxonomy: Knowledge Difficulty: Moderate APA Goal: Outcomes 4.4, 10.2 56. Which of the following statements best expresses the relationship between the central nervous system and the endocrine system? a. They operate entirely independently. b. The endocrine system is part of the central nerv ...
Anatomy of Neuropsychiatry : The New Anatomy of the
Anatomy of Neuropsychiatry : The New Anatomy of the

... not only from new methods of exploring the brain, including new neuroanatomical staining techniques and brain imaging methods in humans, but also from a need to unite our knowledge of brain function and structure with clinical observations. The task is to enable an integration of brain-behavior rela ...
Serotonin in the inferior colliculus fluctuates with behavioral state
Serotonin in the inferior colliculus fluctuates with behavioral state

... variability in 5-HT regulatory mechanisms means that in order to determine the conditions in which 5-HT has an elevated effect on auditory processing, extracellular 5-HT must be measured directly within the auditory system. Concentrations of extracellular 5-HT in the brain are not only region-specif ...
Effects of Brain Damage (cont`d.)
Effects of Brain Damage (cont`d.)

... (cont’d.) • For example, cold remedies exert most of their effects by blocking parasympathetic activity. • Because the flow of sinus fluids is a parasympathetic response, drugs that block the parasympathetic system inhibit sinus flow. • The side effects of cold remedies stem from anti-parasympatheti ...
A neurotoxic regimen of MDMA suppresses behavioral, thermal and
A neurotoxic regimen of MDMA suppresses behavioral, thermal and

... al. 1978a) supports the view that 5-HT, presumably released by these amphetamine analogs, mediates the induction of these behaviors. MDMA also produces a significant increase in body temperature that is thought to be mediated by the activation of 5-HT2 receptors (Nash et al. 1988; Schmidt et al. 199 ...
Effect of PACAP in Central and Peripheral Nerve Injuries
Effect of PACAP in Central and Peripheral Nerve Injuries

... animals are injured from 2 m with a 450 g weight and the skull fracture is prevented by cementing a small stainless-steel disc on the calvaria modeling impact acceleration head injury. Using this model, our light microscopic examination showed that the vehicle- and drug-treated animals subjected to ...
Analysis of Connectivity in the Cat Cerebral Cortex
Analysis of Connectivity in the Cat Cerebral Cortex

... scheme to evolve and improve as more information becomes available. Our cortical map was based principally on the parcellation presented by Cavada and Reinoso-Suarez (1985). It was supplemented by maps for the auditory system taken from Imig and Reale (1980) for areas 4, 5, and 6 from Avendano and R ...
DEPARTAMENT DE FARMACOLOGIA, DE TERAPÈUTICA I DE TOXICOLOGIA
DEPARTAMENT DE FARMACOLOGIA, DE TERAPÈUTICA I DE TOXICOLOGIA

... 6. CONCLUDING REMARKS .......................................................... 197 ...
NIH Public Access
NIH Public Access

... function. In principle, lesion studies could elucidate the causal contribution of vmPFC and amygdala to PTSD by determining if damage to these brain areas changes the likelihood of developing PTSD. However, in an illness such as PTSD that is not amenable to animal lesion studies, this requires the s ...
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Neuropsychology

Neuropsychology studies the structure and function of the brain as they relate to specific psychological processes and behaviors. It is an experimental field of psychology that aims to understand how behavior and cognition are influenced by brain functioning and is concerned with the diagnosis and treatment of behavioral and cognitive effects of neurological disorders. Whereas classical neurology focuses on the physiology of the nervous system and classical psychology is largely divorced from it, neuropsychology seeks to discover how the brain correlates with the mind. It thus shares concepts and concerns with neuropsychiatry and with behavioral neurology in general. The term neuropsychology has been applied to lesion studies in humans and animals. It has also been applied to efforts to record electrical activity from individual cells (or groups of cells) in higher primates (including some studies of human patients). It is scientific in its approach, making use of neuroscience, and shares an information processing view of the mind with cognitive psychology and cognitive science.In practice, neuropsychologists tend to work in research settings (universities, laboratories or research institutions), clinical settings (involved in assessing or treating patients with neuropsychological problems), forensic settings or industry (often as consultants where neuropsychological knowledge is applied to product design or in the management of pharmaceutical clinical-trials research for drugs that might have a potential impact on CNS functioning).
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