• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
John F. MacDonald 2014 - Canadian Association for Neuroscience
John F. MacDonald 2014 - Canadian Association for Neuroscience

... were later found to be blocked by magnesium in a voltage-dependent manner, and required for long-term synaptic modifications thought to underlie some forms of learning. By virtue of their voltage-dependence, NMDA receptors act as molecular coincidence detectors, a characteristic ...
The Nervous System
The Nervous System

... neuron to neuron across gaps called synapses. A sending neuron synthesizes neurotransmitter molecules and bundles them into packages; when the neuron becomes electrically excited, it releases the neurotransmitter molecules into the synapse. Once in the synapse, each molecule may: Dock on a receptor ...
Chapter 10: Sensory Physiology
Chapter 10: Sensory Physiology

... Ascend to limbic system and hypothalamusEmotional Distress ...
here
here

...  transport - mostly into glia (amino acids) ...
powerpoint - Journal of Pharmacology and Experimental
powerpoint - Journal of Pharmacology and Experimental

... ...
Nerve impulses and Synapses Electro
Nerve impulses and Synapses Electro

... • In the brain, excitatory synapses outnumber inhibitory ones about 5 to 1. But: • Inhibitory synapses can create larger hyperpolarizing currents, and are often found on the soma, near the axon hillock, where they can be most effective. • Since one glutamatergic neuron in cortex delivers excitatory ...
9ReceptorTypes1
9ReceptorTypes1

... (depending on the ion channel). • Rapid desensitization (loss of activity) if continuously exposed to nt. • Limits postsynaptic responding when presynaptic neurons are highly active for a period of time. ...
6AOGPFTarget
6AOGPFTarget

... Xenopus laevis spinal neurons. These findings, together with the impaired target selection of cortical GABAergic interneurons lacking CB1Rs, identify endocannabinoids as axon guidance cues and demonstrate that endocannabinoid signaling regulates synaptogenesis and target selection in vivo. ...
Pharmacology II Tutoring: Drugs of abuse
Pharmacology II Tutoring: Drugs of abuse

... • B. Depersonalization ...
Acetate Acetylcholine (ACh)
Acetate Acetylcholine (ACh)

... ...
Psychopharmacology and Other Biologic Treatments
Psychopharmacology and Other Biologic Treatments

... • Widely distributed in the peripheral nervous system • Excitatory neurotransmitters play a major role in mood states. ...
The Journal of Neuroscience
The Journal of Neuroscience

... Correction: In the April 9, 2008 issue’s “This Week in the Journal” summary of the Development/Plasticity/Repair article by Coate et al., there was an error in the third sentence. The term “DP cells” should have been “EP cells.” Thus, the sentence should have read “This week, Coate et al. report tha ...
General Sensory Reception
General Sensory Reception

... sharp and well localized, transmitted by myelinated axons ...
This Week in The Journal - Journal of Neuroscience
This Week in The Journal - Journal of Neuroscience

... K. Grandy, Jiang-Fan Chen, Anne B. Young, and Michael A. Schwarzschild (see pages 10414 –10419) Antagonists for the metabotropic glutamate receptor mGlu5 and the adenosine receptor A2A have shown anti-parkinsonian effects in preclinical studies. These receptors also assemble in heteromeric complexes ...
Central Nervous System Control of Energy and Glucose
Central Nervous System Control of Energy and Glucose

... Jong-Woo Sohn, MD, PhD ...
23Neurotransmitter22012-09
23Neurotransmitter22012-09

... electrical impulses into the synaptic cleft from synaptic vesicles of presynaptic membrane . It then diffuses to the postsynaptic membrane, binds to and activates the receptors present leading to initiation of new electrical signals or inhibition of the post-synaptic neuron. ...
13th Lecture Updated
13th Lecture Updated

...  The final product formed by the sequential action of MAO and COMT is partly conjugated to sulfate or glucuronide derivatives, which are excreted in the urine, but most of it is converted to vanillylmandelic acid and excreted in the urine in this form  In the periphery, neither MAO nor COMT is pri ...
Lecture 8 Basics: Organelles Overview: Types of signaling Types of
Lecture 8 Basics: Organelles Overview: Types of signaling Types of

... Regulatory hormone binds to a g protein-coupled receptor Changes the shape of the receptor, alpha unit releases GDP and binds GTP ...
CNS Autonomic NS
CNS Autonomic NS

... Association areas = integration and direction of voluntary behaviors Fields = areas where sensory information comes in and is integrated into perception ...
ANPS 019 Beneyto-Santonja 11-07
ANPS 019 Beneyto-Santonja 11-07

...  Superficial cutaneous – highly sensitive fine touch and pressure for specific localization  Deep cutaneous – less sensitive crude touch and pressure for less specific localization  Barorecptors detect internal pressure (blood vessels, bladder, GI)  Proprioceptors/Joint receptors (monitor limb p ...
Function of Neurotransmitters
Function of Neurotransmitters

... ...
signal transduction the ligand-gated ion channels
signal transduction the ligand-gated ion channels

... • High concentrations in the spinal cord and brain stem • Inhibitory neurotransmitter • Chloride channel • Oligomeric transmembrane protein comprised of 5 subunits • Strychnine is a competitive glycine antagonist (powerful convulsant) • Strychnine-sensitive inhibitory glycine receptor ...
General Senses Complete
General Senses Complete

... Interoceptors (visceroceptors): respond to stimuli within the body Are found in the internal organs Include stretch receptors (found in the walls of hollow organs) Propriceptors: respond to internal stimuli but are restricted to skeletal muscles, tendons, joints, ligaments, and connective tissue cov ...
013368718X_CH31_483
013368718X_CH31_483

... Chapter 31 Vocabulary Review For Questions 1–10, match the term with its description. ...
Midterm 2 review - UCSD Cognitive Science
Midterm 2 review - UCSD Cognitive Science

... -Limbic System possess amygdala and hippocampus which are important for the association between rewarding emotions and stimuli that produced said award 3) Mesocoritcal VTA to Prefrontal Cortex -Working Memory and Planning NE Involved in attention, vigilance and stress responses Major Pathway, from ...
< 1 ... 198 199 200 201 202 203 204 205 >

Endocannabinoid system

The endocannabinoid system is a group of neuromodulatory lipids and their receptors in the brain that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis and, broadly speaking, includes: The endogenous arachidonate-based lipids, anandamide (N-arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG); these are known as ""endocannabinoids"" and are physiological ligands for the cannabinoid receptors. Endocannabinoids are all eicosanoids. The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide hydrolase or monoacylglycerol lipase. The cannabinoid receptors CB1 and CB2, two G protein-coupled receptors that are located in the central and peripheral nervous systems.The neurons, neural pathways, and other cells where these molecules, enzymes, and one or both cannabinoid receptor types are all colocalized form the endocannabinoid system.The endocannabinoid system has been studied using genetic and pharmacological methods. These studies have revealed that cannabinoids act as neuromodulators for a variety of processes, including motor learning, appetite, and pain sensation, among other cognitive and physical processes. The localization of the CB1 receptor in the endocannabinoid system has a very large degree of overlap with the orexinergic projection system, which mediates many of the same functions, both physical and cognitive. Moreover, CB1 is colocalized on orexin projection neurons in the lateral hypothalamus and many output structures of the orexin system, where the CB1 and orexin receptor 1 (OX1) receptors physically and functionally join together to form the CB1–OX1 receptor heterodimer.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report