Hypersensitivity Reactions to Biological Drugs
... Strictly speaking, biological drugs are defined as drugs obtained using biotechnology that act on the immune system. They encompass monoclonal antibodies, fusion proteins, and cytokines. Although they are restricted to specific diseases, they have been increasingly used in recent years, with the con ...
... Strictly speaking, biological drugs are defined as drugs obtained using biotechnology that act on the immune system. They encompass monoclonal antibodies, fusion proteins, and cytokines. Although they are restricted to specific diseases, they have been increasingly used in recent years, with the con ...
ANTHELMINTIC ACTIVITY OF SYMPLOCOS RACEMOSA
... which uses the herbal constituents in some or the other form, crud drug are not so effective because they have not been tested for efficacy according to rigid pharmacological standards. As the constituents derived from the medicinal plants proved the cure the medicinal plants proved to cure the huma ...
... which uses the herbal constituents in some or the other form, crud drug are not so effective because they have not been tested for efficacy according to rigid pharmacological standards. As the constituents derived from the medicinal plants proved the cure the medicinal plants proved to cure the huma ...
PRODUCT MONOGRAPH DESIPRAMINE
... commonly observed side effects of the drug. Desipramine hydrochloride causes ECG changes such as prolongation of the P-R interval and a decreased magnitude with an increased width of the T wave. These ECG changes are seen most frequently in elderly patients as is postural hypotension. Desipramine hy ...
... commonly observed side effects of the drug. Desipramine hydrochloride causes ECG changes such as prolongation of the P-R interval and a decreased magnitude with an increased width of the T wave. These ECG changes are seen most frequently in elderly patients as is postural hypotension. Desipramine hy ...
Guidance for timing of medication
... Ideally doses should not be omitted as this poses a clinical risk, but if the interval between doses if too close there are also risks of side effects and in some cases increased toxic effects, (e.g. paracetamol, lithium). Clinical judgement and/or advice from a prescriber or the pharmacy team shoul ...
... Ideally doses should not be omitted as this poses a clinical risk, but if the interval between doses if too close there are also risks of side effects and in some cases increased toxic effects, (e.g. paracetamol, lithium). Clinical judgement and/or advice from a prescriber or the pharmacy team shoul ...
et al. Madhu E. Nicholas* , Shanker Panaganti , L. Prabakaran
... Gastrointestinal transit varies from 1 hr to 3 hrs depending upon the condition (fasting or non-fasting). Normally, the small intestinal transit is not influenced by the physical state, size of the dosage form and presence of food in the stomach. The mean transit time of the dosage form is about 3-4 ...
... Gastrointestinal transit varies from 1 hr to 3 hrs depending upon the condition (fasting or non-fasting). Normally, the small intestinal transit is not influenced by the physical state, size of the dosage form and presence of food in the stomach. The mean transit time of the dosage form is about 3-4 ...
spc-doc_PL 20416-0081 - Medicines and Healthcare products
... The antiparkinson effects of levodopa may be impaired by haloperidol. The dosage of anticonvulsants may need to be increased to take account of the lowered seizure threshold. Haloperidol is an inhibitor of CYP 2D6. Haloperidol inhibits the metabolism of tricyclic antidepressants, thereby increasing ...
... The antiparkinson effects of levodopa may be impaired by haloperidol. The dosage of anticonvulsants may need to be increased to take account of the lowered seizure threshold. Haloperidol is an inhibitor of CYP 2D6. Haloperidol inhibits the metabolism of tricyclic antidepressants, thereby increasing ...
hydromorphone
... • You should also not take hydromorphone if you have: · a bowel obstruction called paralytic ileus; or · if you are having an asthma attack. • Do not take hydromorphone if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilec ...
... • You should also not take hydromorphone if you have: · a bowel obstruction called paralytic ileus; or · if you are having an asthma attack. • Do not take hydromorphone if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilec ...
Clinical relevance of the small intestine as an organ of
... ***Note: Figures may be missing from this format of the document Abstract: Most drugs are taken orally. For those intended to act systemically, a significant fraction of the dose can be eliminated during its first passage through a sequence of organs before entry into the general circulation. For so ...
... ***Note: Figures may be missing from this format of the document Abstract: Most drugs are taken orally. For those intended to act systemically, a significant fraction of the dose can be eliminated during its first passage through a sequence of organs before entry into the general circulation. For so ...
Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington
... Drugs that stimulate a specific area of the brain ...
... Drugs that stimulate a specific area of the brain ...
Sonophoresis - International Journal of Pharmacy and Technology
... induce sinusoidal density variation. At frequencies greater than 1 MHz, the density variations occur so rapidly that a small gaseous nucleus cannot grow and cavitational effects cease. But other effects due to density variations, such as generation of cyclic stresses because of density changes that ...
... induce sinusoidal density variation. At frequencies greater than 1 MHz, the density variations occur so rapidly that a small gaseous nucleus cannot grow and cavitational effects cease. But other effects due to density variations, such as generation of cyclic stresses because of density changes that ...
Bulletin #103
... Note: Change re: Submission of Triplicate Information The supplementary information section regarding the Triplicate Prescription Program (starting on page 48 at the back of the Formulary) has been updated, to reflect changes to the process for submission of information. In the fall 2004, the Drug ...
... Note: Change re: Submission of Triplicate Information The supplementary information section regarding the Triplicate Prescription Program (starting on page 48 at the back of the Formulary) has been updated, to reflect changes to the process for submission of information. In the fall 2004, the Drug ...
Prescription Drug Cost Sharing - Associations With Medication and
... example, changing office visit copayments affects how frequently patients see a physician and, hence, the number of prescriptions they receive. Poor features include analyses that do not control for other factors that might be changing, including observations before and after a benefit change with n ...
... example, changing office visit copayments affects how frequently patients see a physician and, hence, the number of prescriptions they receive. Poor features include analyses that do not control for other factors that might be changing, including observations before and after a benefit change with n ...
BASS & ULLMAN, I?G.
... bronchodilators was discussed in a recent article in the FDA’s own consumer publication, the FDA Consumer which was published after the 1995 proposal to reclassify ephedrine as a prescription ...
... bronchodilators was discussed in a recent article in the FDA’s own consumer publication, the FDA Consumer which was published after the 1995 proposal to reclassify ephedrine as a prescription ...
Penicillins
... Similar to vancomycin in mechanism and antimicrobial spectrum Can be given im as well as iv Less adverse reactions ...
... Similar to vancomycin in mechanism and antimicrobial spectrum Can be given im as well as iv Less adverse reactions ...
MDMA (Ecstasy/Molly)
... memory and attention problems decreased appetite decreased interest in and pleasure from sex It's possible that some of these effects may be due to the combined use of MDMA with other drugs, especially marijuana. What are other health effects of MDMA? High doses of MDMA can affect the body’s a ...
... memory and attention problems decreased appetite decreased interest in and pleasure from sex It's possible that some of these effects may be due to the combined use of MDMA with other drugs, especially marijuana. What are other health effects of MDMA? High doses of MDMA can affect the body’s a ...
Chemicals/drugs-hepatotoxicants: An overview
... Rifampicin is a macro cyclic antibiotic. Patients on concurrent Rifampicin therapy have an increased incidence of hepatitis. This has been postulated due to Rifampicin-induced cytochrome P450 enzyme-induction, causing an increased production of the toxic metabolites from acetyl hydrazine (AcHz). The ...
... Rifampicin is a macro cyclic antibiotic. Patients on concurrent Rifampicin therapy have an increased incidence of hepatitis. This has been postulated due to Rifampicin-induced cytochrome P450 enzyme-induction, causing an increased production of the toxic metabolites from acetyl hydrazine (AcHz). The ...
hypertension in diabetes medication algorithm
... Add diuretic (chlorthalidone 12.5 or HCTZ 12.5/daymonitor SE, K, glucose, and adherence ); f/u in 2 weeks yes ...
... Add diuretic (chlorthalidone 12.5 or HCTZ 12.5/daymonitor SE, K, glucose, and adherence ); f/u in 2 weeks yes ...
Naltrexone potentiates anti-HIV-1 activity of antiretroviral drugs in
... presently unknown. A similar bell-shaped concentration-response effect seen with the KOR antagonist, nor-BNI, suggests a possible interaction of naloxone with KOR on CD4+ lymphocytes is involved. The expression of KOR by T lymphocytes has been characterized both in murine (Alicea et al., 1998; Ignat ...
... presently unknown. A similar bell-shaped concentration-response effect seen with the KOR antagonist, nor-BNI, suggests a possible interaction of naloxone with KOR on CD4+ lymphocytes is involved. The expression of KOR by T lymphocytes has been characterized both in murine (Alicea et al., 1998; Ignat ...
Company Description
... completely new ground. They offered a medicinal product that resulted in millions of men – and their partners – regaining the ability to have a functional sex life. Thus, they were responsible for injecting new life, lust and vitality in relationships afflicted by erectile dysfunction. The market fo ...
... completely new ground. They offered a medicinal product that resulted in millions of men – and their partners – regaining the ability to have a functional sex life. Thus, they were responsible for injecting new life, lust and vitality in relationships afflicted by erectile dysfunction. The market fo ...
Carbamazepine (Tegretol)
... Carbamazepine is eliminated almost by the metabolic route,with less than 2% of an oral dose being excreted unchanged in the urine .Clearance values are difficult to estimate because bioavailability is uncertain. Nevertheless ,the average clearance value appears to be approximately 0.064 L/Kg in pati ...
... Carbamazepine is eliminated almost by the metabolic route,with less than 2% of an oral dose being excreted unchanged in the urine .Clearance values are difficult to estimate because bioavailability is uncertain. Nevertheless ,the average clearance value appears to be approximately 0.064 L/Kg in pati ...
DEVELOPMENT AND VALIDATION OF HPTLC METHOD FOR SIMULTANEOUS
... Development and validation of simple, rapid, precise, accurate and sensitive HPTLC method for the simultaneous estimation of Rosuvastatin calcium and Aspirin in bulk and in capsule dosage form. The mobile phase consisting of Ethyl acetate:Toluene:Glacial acetic acid (6:3:1 v/v/v) and wavelength of d ...
... Development and validation of simple, rapid, precise, accurate and sensitive HPTLC method for the simultaneous estimation of Rosuvastatin calcium and Aspirin in bulk and in capsule dosage form. The mobile phase consisting of Ethyl acetate:Toluene:Glacial acetic acid (6:3:1 v/v/v) and wavelength of d ...
CHB_Prescribe_012_ EPR clinical checking and supply requests
... Select ACCEPT to denote this medication is clinically suitable for this patient. ...
... Select ACCEPT to denote this medication is clinically suitable for this patient. ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.