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Cholinergic modulation of cognitive processing: insights drawn from computational models Kishan Gupta
Cholinergic modulation of cognitive processing: insights drawn from computational models Kishan Gupta

... be dissociated by their binding affinity for muscarine and nicotine. At present, computational models of cholinergic function do not usually focus on dissociating the contribution of each of these receptor types. However, each has distinct properties that would have differential functional influence ...
Understanding mirror neurons - LIRA-Lab
Understanding mirror neurons - LIRA-Lab

... 3. A model of area F5 and the mirror system The results summarized in the previous sections tell us of the central role of F5 in the control and recognition of manipulative actions: the common interpretation proposed by (Luppino & Rizzolatti, 2000) and (Fagg & Arbib, 1998) considers F5 a part of a l ...
full text pdf
full text pdf

... from the eye into the brain for information processing in the central nervous system (CNS). One of the first relay centers in this pathway is the dorsal Lateral Geniculate Nucleus (dLGN), a thalamic center in the diencephalon. Each dLGN hemisphere receives major input from the optic nerves and from ...
PDF - Oxford Academic - Oxford University Press
PDF - Oxford Academic - Oxford University Press

... pictures after 30 s, while fMRI images were obtained. The results showed an immediate (30 s) and long-lasting (3 day) decrease in neural activity in bilateral occipitotemporal cortex following both nameable and nonsense object repetition. In addition, decreases in left inferior frontal activity were ...
How do dendrites take their shape?
How do dendrites take their shape?

... course of much of the twentieth century, the prevailing belief that axons take the more active role in wiring the brain and in establishing synaptic specificity led researchers to focus on the development of axons more than that of the dendrites. In addition, the complexity and diversity of dendriti ...
~  Pergamon
~ Pergamon

... Abstract--The prefrontal cortex of primates is an integrative centre for sensory, cognitive, mnemonic and emotional processes. The cellular features which contribute to the functional specialization of its subsectors are poorly understood. In this study we determined the distribution of nicotinamide ...
BETA ACTIVITY: A CARRIER FOR VISUAL ATTENTION
BETA ACTIVITY: A CARRIER FOR VISUAL ATTENTION

... bands of the EEG have been long studied in clinical research because of their putative functional importance. Old experimental results indicated that repetitive stimulation of the visual pathway evoked synchronous responses at the cortical level with gain depending on frequency: oscillations within ...
The role of temporal parameters in a thalamocortical model of analogy
The role of temporal parameters in a thalamocortical model of analogy

... A more difficult issue is how filtering can be done, i.e., how can input-driven cortical activity be distinguished from cortex-driven cortical activity? As suggested in [27] and [28], the TRN is a promising location where such a filtering can occur. The basic idea is that the reticular neurons recei ...
Lecture 6 th week
Lecture 6 th week

... • It originates in the cerebral cortex and sends impulses to the nerves of the respiratory muscles via the corticospinal tracts. In addition, ingoing impulses from many parts of the body modify the activity of the respiratory centers and consequently alter the outgoing impulses to the respiratory mu ...
- Stem-cell and Brain Research Institute
- Stem-cell and Brain Research Institute

... Understanding how the cerebral cortex processes information is a major aim of neurobiology today, with important implications for disciplines ranging from psychiatry to the designing of living machines. Numerous investigative techniques at different levels are used to this end, including functional ...
Article - Leslie Vosshall - The Rockefeller University
Article - Leslie Vosshall - The Rockefeller University

... neurons had such dense arborization within the V glomerulus that reconstructing and quantifying the branches proved to be technically impossible (data not shown). To examine whether CO2 exposure induces functional changes in either population of LNs, we used calcium imaging to measure CO2-evoked res ...
synaptic connections made by axons
synaptic connections made by axons

... useful function (Mackel et al. 1983), presumably because many regrowing fibres reach inappropriate targets after extending along Bungner bands previously occupied by other axons (Horch and Burgess, 1980). Thus, while axonal extension is an unavoidable step in the repair process, it does not ensure t ...
Parallel basal ganglia circuits for voluntary and
Parallel basal ganglia circuits for voluntary and

... et al., 2012), and eating/drinking (Nakamura and Katakura, 1995). Triggered by particular sensory inputs or internal states, these mechanisms can work independently to generate adaptive movements (e.g. vestibuloocular reflex). However, the whole behaviour could become uncontrollable if these motor me ...
- Donders Institute for Brain, Cognition and Behaviour
- Donders Institute for Brain, Cognition and Behaviour

... condition differs from the other three conditions in terms of reaction time and errors. Therefore, we also performed a planned contrast, using the following contrast weights: +3 for contralateral-movement-to-dots and –1 for the three other conditions. This allowed us to test our hypothesis that brai ...
The Human Mirror Neuron System and Embodied
The Human Mirror Neuron System and Embodied

... created through visual observation as well as from the proprioceptive information received during action execution. Through association, the motor ‘‘image’’ was then invoked whenever we thought of a movement, or what he called ‘‘ideomotor action’’ (James, 1890). Greenwald (1970) extended these ideas ...
The Teen Brain on Marijuana
The Teen Brain on Marijuana

... Several of these studies followed individuals from childhood (ages 6 or younger), before marijuana use began, all the way into their late 20’s. So, they were able to determine whether symptoms of mental illness were present BEFORE marijuana use initiation, and perhaps contributed to individuals bec ...
View/Open - Minerva Access
View/Open - Minerva Access

... owl. We demonstrate a similar selective potentiation for the recurrent connections in a network with axonal delays corresponding to the period of incoming oscillatory activity with frequencies in the range of 100-300Hz. For lower frequency oscillations, such as gamma (60Hz), we show that multiple, r ...
Neuronal fiber tracts connecting the brain and ventral nerve cord of
Neuronal fiber tracts connecting the brain and ventral nerve cord of

... behaviors involving movement of the wings, legs, and abdomen) and subesophageal ganglion (CPGs controlling behaviors involving the mouth parts; Burrows, 1996; Heinrich, 2002). Given that many behaviors make use of the same muscles/ motor neurons (e.g., wing beating in flies is part of flight and matin ...
What Can an Orbitofrontal Cortex- Endowed Animal
What Can an Orbitofrontal Cortex- Endowed Animal

... [LO] areas).4 This latter group of structures (AIv, AIp, VLO, LO) receives direct projections from rodent piriform cortex and responds with short-latency action potentials to electrical stimulation of the olfactory bulb.5 From electrophysiological recordings in rodents, it is evident that these same ...
The Medial Frontal Cortex and the Rapid Processing of Monetary
The Medial Frontal Cortex and the Rapid Processing of Monetary

... the response- or error-feedback information. ...
Functional Anatomy, Physiology and Clinical Aspects of Basal Ganglia
Functional Anatomy, Physiology and Clinical Aspects of Basal Ganglia

... Neuroimaging for Clinicians – Combining Research and Practice ...
Interactions Between Premotor and Motor Cortices in Non
Interactions Between Premotor and Motor Cortices in Non

... based on the properties of particular cortical areas, but focused on the transmission of information between areas: They suggested that ‘‘the transformation of an object’s intrinsic properties into specific grips takes place in a circuit that is formed by the inferior parietal lobule and the inferio ...
How microglia kill neurons
How microglia kill neurons

... microglia are unable to provide these protective functions. For example, microglia express and release IGF1 that supports neurons, and this expression is greatly reduced by lipopolysaccharide (LPS), resulting in neuronal death if there are no other neurotrophins present (Chhor et al., 2013). This re ...
Energy balance
Energy balance

... • Adenosine builds up in the brain during wakefulness. – We have low levels just after sleeping. – We have high levels after being awake for a long time. ...
Leap 2 - Entire - Teacher Enrichment Initiatives
Leap 2 - Entire - Teacher Enrichment Initiatives

... receptor areas on the dendrite of the next neuron. The receptors are specialized, so they receive only their “own” neurotransmitter. As the neurotransmitter is received by the receptor, it triggers electrical impulses which travel through the neuron to the axon tip at the next synapse and the proces ...
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Activity-dependent plasticity

A defining feature of the brain is its capacity to undergo changes based on activity-dependent functions, also called activity-dependent plasticity. Its ability to remodel itself forms the basis of the brain’s capacity to retain memories, improve motor function, and enhance comprehension and speech amongst other things. It is this trait to retain and form memories that is functionally linked to plasticity and therefore many of the functions individuals perform on a daily basis. This plasticity is the result of changed gene expression that occurs because of organized cellular mechanisms.The brain’s ability to adapt toward active functions has allowed humans to specialize in specific processes based on relative use and activity. For example, a right-handed person may perform any movement poorly with his/her left hand but continuous practice with the less dominant hand can make both hands just as able. Another example is if someone was born with a neurological disorder such as autism or had a stroke that resulted in a disorder, then they are capable of retrieving much of their lost function by practicing and “rewiring” the brain in order to incorporate these lost manners. Thanks to the pioneers within this field, many of these advances have become available to most people and many more will continue to arrive as new features of plasticity are discovered.
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