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Nervous Systems
Nervous Systems

... 1. A nerve impulse reaches end of presynaptic neuron. 2. Presynaptic membrane depolarizes, opening voltage-gated Ca2+ channels. – Ca2+ ions diffuse into presynaptic neuron ...
Nervous System I - Laurel County Schools
Nervous System I - Laurel County Schools

Nervous System I - Laurel County Schools
Nervous System I - Laurel County Schools

... reaches the end of an axon, this opens two channels Na+ and Ca2+ This surge of Ca2+ acts as a messenger, directing synaptic vesicles to empty contents. Then the neurotransmitter diffuses across the synaptic cleft A neurotransmitter reaching the dendrite or cell body on the distal side of the cleft t ...
The nervous system
The nervous system

... receives sensory stimuli, and transfers the information directly to a motor neuron or to the brain for processing. ...
File
File

Answer on Question#47890 - Biology - Other
Answer on Question#47890 - Biology - Other

... other, changing their relative position as the muscle contracts and relaxes. Contraction is triggered when an action potential (the electric signal from neurons that tells muscles to contract) reaches the junction between neuron and muscle. Depolarization of the axon terminal causes the release of n ...
Major Divisions in the Central Nervous System
Major Divisions in the Central Nervous System

... 1. Influx of Ca2+ on presynaptic neuron 2. Causes synaptic vesicles to fuse with the membrane of the presynaptic neuron. 3. The vesicles release neurotransmitter molecules into the synaptic cleft. These molecules diffuse across the cleft and bind to the receptors of ion channels embedded in the post ...
Name: Block: Date
Name: Block: Date

... A MOTOR neuron has a long axon and short dendrites. In the first part of the nerve impulse, the ion SODIUM moves to the inside of the neuron. The junction between one neuron and another is called a SYNAPSE. Each division of the autonomic nervous system controls the same organs, but they generally ha ...
CHAPTER 12 AND 13 OUTLINE
CHAPTER 12 AND 13 OUTLINE

... • • Correspond to gap junctions found in other cell types • • Contain intercellular protein channels • • Permit ion flow from one neuron to the next • • Are found in the brain and are abundant in embryonic tissue Chemical Synapses • • Specialized for the release and reception of neurotransmitters • ...
Physiology Ch 45 p543-557 [4-25
Physiology Ch 45 p543-557 [4-25

... neuropeptides are most often for prolonged signals Small-Molecule, Rapid Acting Transmitters – most often synthesized in cytosol and absorbed by active transport into vesicles at terminal. After depolarization, few vesicles are released into cleft within 1ms; neurotransmitter acts on postsynaptic ne ...
Cranial Nerves
Cranial Nerves

... The oculomotor nerve (CN III) originates from the ventral midbrain and passes through the superior orbital fissure on its way to the eye. CN III innervates three of the four rectus muscles (superior, inferior, and medial) and the inferior oblique muscle. Other muscles innervated by CN III are the le ...
Histology of Nervous Tissue
Histology of Nervous Tissue

... • Voltage change due to ion flow through chemically (ligand) or mechanically gated channels • Amount of voltage change (graded) dependent on # of gates open at one time and how long – Change is localized (not conducted) – Change may be depolarization or hyperpolarization • Usually limited to dendrit ...
Document
Document

... • One neuron will transmit info to another neuron or to a muscle or gland cell by releasing chemicals called neurotransmitters. • The site of this chemical interplay is known as the synapse. – An axon terminal (synaptic knob) will abut another cell, a neuron, muscle fiber, or gland cell. – This is t ...
Lesson 4 Section 9.2 Electrochemical Impulse
Lesson 4 Section 9.2 Electrochemical Impulse

... This happens from the axon of one neuron to the dendrite of another Neurons have a rich supply of positive (+) and negative (-) ions both inside and outside the cell Negative ions are too large to pass through the cell membrane The positive ions do have the ability to diffuse in and out of the cell ...
How is the Nervous System Organized? Class Objectives:
How is the Nervous System Organized? Class Objectives:

... Before an impulse can go across the synapse, it must be converted into a chemical message (Neurotransmitters). This is an electrochemical process ...
mspn1a
mspn1a

... length. Describe how gamma motor neurons innervate the muscle spindle. Explain why gamma motor neuron enervation is important in maintaining muscle spindle function, especially during contraction. Gamma motor neurons innervate the polar ends of the intrafusal muscle fibers. They do not innervate ext ...
Human Vision: Electrophysiology and Psychophysics
Human Vision: Electrophysiology and Psychophysics

... is released in synapse Threshold: energy expenditure to open Na channels ...
Neurology-Movement Disorders
Neurology-Movement Disorders

Nervous Systems - Groupfusion.net
Nervous Systems - Groupfusion.net

... 1. A nerve impulse reaches end of presynaptic neuron. 2. Presynaptic membrane depolarizes, opening voltage-gated Ca2+ channels. – Ca2+ ions diffuse into presynaptic neuron ...
action potential
action potential

Reflex Arc - Point Loma High School
Reflex Arc - Point Loma High School

... The sensory neurons pass through the spinal cord which allows reflex actions to occur relatively quickly by activating spinal motor neurons without the delay of steering signals through the brain, although the brain will receive sensory input while the reflex action occurs. ...
Cell types: Muscle cell Adipocyte Liver cell Pancreatic cell Example
Cell types: Muscle cell Adipocyte Liver cell Pancreatic cell Example

... contain Nissl substance and is called an axon hillock. The plasma membrane of the axon is called the axolemma, and the cytoplasm contained in it is called axoplasm. The axoplasm does not contain the Nissl substance or Golgi apparatus, but it does contain mitochondria, microtubules, and neurofilament ...
No Pain, No Gain: Understanding Muscle Pain
No Pain, No Gain: Understanding Muscle Pain

Modeling and Imagery
Modeling and Imagery

... • So signal transmission is complex, determined by total strength of arriving signal and subsequent strength of descending signal ...
No Slide Title
No Slide Title

... Copyright 2000, All Rights Reserved. Material is in logical order: see texts, lab. outline for characteristics To advance to next slide: -click mouse or “page down” To return to the previous slide: - press “page up” ...
< 1 ... 166 167 168 169 170 171 172 173 174 ... 209 >

Neuromuscular junction



A neuromuscular junction (sometimes called a myoneural junction) is a junction between nerve and muscle; it is a chemical synapse formed by the contact between the presynaptic terminal of a motor neuron and the postsynaptic membrane of a muscle fiber. It is at the neuromuscular junction that a motor neuron is able to transmit a signal to the muscle fiber, causing muscle contraction.Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy. Synaptic transmission at the neuromuscular junction begins when an action potential reaches the presynaptic terminal of a motor neuron, which activates voltage-dependent calcium channels to allow calcium ions to enter the neuron. Calcium ions bind to sensor proteins (synaptotagmin) on synaptic vesicles, triggering vesicle fusion with the cell membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft. In vertebrates, motor neurons release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors (nAChRs) on the cell membrane of the muscle fiber, also known as the sarcolemma. nAChRs are ionotropic receptors, meaning they serve as ligand-gated ion channels. The binding of ACh to the receptor can depolarize the muscle fiber, causing a cascade that eventually results in muscle contraction.Neuromuscular junction diseases can be of genetic and autoimmune origin. Genetic disorders, such as Duchenne muscular dystrophy, can arise from mutated structural proteins that comprise the neuromuscular junction, whereas autoimmune diseases, such as myasthenia gravis, occur when antibodies are produced against nicotinic acetylcholine receptors on the sarcolemma.
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