Modelling of tolerance and rebound in normal and
... potential risks can be minimized. In this thesis nicotinic acid (NiAc)-induced changes in non-esterified fatty acids (NEFA) were used as a tool to investigate key determinants of tolerance and rebound in normal Sprague Dawley and in obese Zucker rats, a disease model of dyslipidaemia. The aim of the ...
... potential risks can be minimized. In this thesis nicotinic acid (NiAc)-induced changes in non-esterified fatty acids (NEFA) were used as a tool to investigate key determinants of tolerance and rebound in normal Sprague Dawley and in obese Zucker rats, a disease model of dyslipidaemia. The aim of the ...
Document
... The ability of a drug's binding to receptor. A drug's affinity for binding its receptor determines the concentration of drug required to occupy 50% its receptor or elicits 50% Emax. The greater concentration required, the weaker affinity of a drug. ...
... The ability of a drug's binding to receptor. A drug's affinity for binding its receptor determines the concentration of drug required to occupy 50% its receptor or elicits 50% Emax. The greater concentration required, the weaker affinity of a drug. ...
SPECTROPHOTOMETRIC DETERMINATION OF AMILORIDE IN BULK AND PHARMACEUTICAL FORMULATIONS Research Article
... the range of 20-100 μg/ml of amiloride for both the methods. The Beer’s law limits, regression equations and correlation coefficient values were evaluated. The linearity of calibration graphs were proved by the high values of the correlation coefficient (R). Accuracy and precession of the two method ...
... the range of 20-100 μg/ml of amiloride for both the methods. The Beer’s law limits, regression equations and correlation coefficient values were evaluated. The linearity of calibration graphs were proved by the high values of the correlation coefficient (R). Accuracy and precession of the two method ...
Class Problems
... A 2-Ib ball is thrown in the direction shown with an initial speed vA = 18 ft/s. Determine the time needed for it to reach its highest point B and the speed at which it is traveling at B. Use the principle of impulse and momentum for the solution. (See diagram in the textbook.) ...
... A 2-Ib ball is thrown in the direction shown with an initial speed vA = 18 ft/s. Determine the time needed for it to reach its highest point B and the speed at which it is traveling at B. Use the principle of impulse and momentum for the solution. (See diagram in the textbook.) ...
Formulation and evaluation of Pseudoephedrine hydrochloride and
... Isopropyl Alcohol Methylene Chloride ...
... Isopropyl Alcohol Methylene Chloride ...
DEVELOPMENT AND CHARACTERIZATION OF LAMOTRIGINE ORODISPERSIBLE TABLETS: INCLUSION COMPLEX WITH HYDROXYPROPYL Β CYCLODEXTRIN
... Bitter taste of drug and solubility becomes hurdles for formulating orodispersible tablets (ODT) hence there is strong clinical need to explore any technique to enhance its solubility and simultaneously by masking of taste. β‐cyclodextrin is known to form inclus ...
... Bitter taste of drug and solubility becomes hurdles for formulating orodispersible tablets (ODT) hence there is strong clinical need to explore any technique to enhance its solubility and simultaneously by masking of taste. β‐cyclodextrin is known to form inclus ...
title of topic
... of bronchoconstriction and airflow limitation that is partly reversible either spontaneously or with treatment [1]. In 2007, it was estimated that 300 million people worldwide suffer from asthma and is expected to increase by more than 100 million by 2025[2]. The drugs currently used in treating ast ...
... of bronchoconstriction and airflow limitation that is partly reversible either spontaneously or with treatment [1]. In 2007, it was estimated that 300 million people worldwide suffer from asthma and is expected to increase by more than 100 million by 2025[2]. The drugs currently used in treating ast ...
In Vitro Study of The Effect of Some Drugs on Leishmania Donavani
... competition for survival. In the present study most types of drugs used have significant difference between the growth rates of parasites and control group in the first day which mean that they have killing effect on promastigotes in away or another according to their mechanisms of action[16]. In th ...
... competition for survival. In the present study most types of drugs used have significant difference between the growth rates of parasites and control group in the first day which mean that they have killing effect on promastigotes in away or another according to their mechanisms of action[16]. In th ...
STABILITY OF CEFPIROME SULFATE IN AQUEOUS SOLUTIONS
... dizziness). All adverse effects are of mild or moderate severity and do not last long. Spontaneous improvement leading to complete recovery can be observed. As most of the side effects of β-lactams are caused by the generation of degradation products, it is important to estimate their stability. Ear ...
... dizziness). All adverse effects are of mild or moderate severity and do not last long. Spontaneous improvement leading to complete recovery can be observed. As most of the side effects of β-lactams are caused by the generation of degradation products, it is important to estimate their stability. Ear ...
Document
... When administered with calcium channel blockers and digoxin, it causes lowering of blood pressure and heart rate to dangerous levels. In patients with coronary artery disease, abruptly stopping metoprolol can suddenly worsen angina, and occasionally precipitate heart attacks. If it is necessary ...
... When administered with calcium channel blockers and digoxin, it causes lowering of blood pressure and heart rate to dangerous levels. In patients with coronary artery disease, abruptly stopping metoprolol can suddenly worsen angina, and occasionally precipitate heart attacks. If it is necessary ...
WITHANIA SOMNIFERA PARACETAMOL-INDUCED LIVER DAMAGE IN RATS
... Objective: The aim of this study was to evaluate the hepatoprotective and antioxidant effects of Withania somnifera against Paracetamol-induced liver injury in rats. Methods: In the present study, the protective effect of Withania somnifera was investigated against Paracetamol-induced hepatotoxicity ...
... Objective: The aim of this study was to evaluate the hepatoprotective and antioxidant effects of Withania somnifera against Paracetamol-induced liver injury in rats. Methods: In the present study, the protective effect of Withania somnifera was investigated against Paracetamol-induced hepatotoxicity ...
In Vitro-In Vivo Correlation (IVIVC) and Determining
... administered in a format (tablet or capsules) which releases the drug into solution over time. Then effectively the tablet or capsules will serve the same process as continuous dosing which may be broken down in different, equal or un-equal, intervals. Therefore, in reality, the drug administered us ...
... administered in a format (tablet or capsules) which releases the drug into solution over time. Then effectively the tablet or capsules will serve the same process as continuous dosing which may be broken down in different, equal or un-equal, intervals. Therefore, in reality, the drug administered us ...
Oral Extended Release Drug Delivery System: A Promising Approach
... Therapeutic range of the drug must be high. A drug for ER drug delivery system because more lipid soluble drug ERDDS should have therapeutic range wide enough such will not partition out of the lipid membrane once it gets in that variations in the release do not result in concentration the membrane. ...
... Therapeutic range of the drug must be high. A drug for ER drug delivery system because more lipid soluble drug ERDDS should have therapeutic range wide enough such will not partition out of the lipid membrane once it gets in that variations in the release do not result in concentration the membrane. ...