Natural Supplements Proven To Lower Cholesterol
... humans demonstrate that guggulsterone can produce a cholesterol reduction of 14-27%, in 4-12 weeks, and a 22-30% drop in blood triglyceride levels, in patients with high cholesterol and/or high triglycerides. A striking feature is its lack of toxicity. Unlike other cholesterol-lowering drugs, ...
... humans demonstrate that guggulsterone can produce a cholesterol reduction of 14-27%, in 4-12 weeks, and a 22-30% drop in blood triglyceride levels, in patients with high cholesterol and/or high triglycerides. A striking feature is its lack of toxicity. Unlike other cholesterol-lowering drugs, ...
EFAVIRENZ RAT MODEL Research Article
... Drugs that inhibit CYP450 enzymes, generally lead to decreased metabolism of other drugs metabolized by the same enzyme. The decreased metabolism can result in higher drug levels and increased potential for toxicity. When drugs that induce CYP450 enzymes are administered to a ...
... Drugs that inhibit CYP450 enzymes, generally lead to decreased metabolism of other drugs metabolized by the same enzyme. The decreased metabolism can result in higher drug levels and increased potential for toxicity. When drugs that induce CYP450 enzymes are administered to a ...
PREPARATION, OF TACROLIMUS Research Article
... approved by the Institutional Animal Ethics Committee (IAEC) of Institute of Pharmacy, Nirma University, Ahmadabad as per guidelines of Committee for Purpose of Control and Supervision of Experiments on Animal (CPCSEA), Ministry of Social Justice and Empowerment, Government of India. Protocol number ...
... approved by the Institutional Animal Ethics Committee (IAEC) of Institute of Pharmacy, Nirma University, Ahmadabad as per guidelines of Committee for Purpose of Control and Supervision of Experiments on Animal (CPCSEA), Ministry of Social Justice and Empowerment, Government of India. Protocol number ...
training workshop on pharmaceutical quality, good manufacturing
... Assay not sufficiently sensitive for single-dose study ...
... Assay not sufficiently sensitive for single-dose study ...
Pharmacologically Active Metabolites of Currently - J
... artemether gives pharmacologically active O-desmethylvenlafaxine, O-desmethylivabradine and dihydroartemisinin, respectively.1921) Ivabradine also forms active metabolite by N-demethylation.20) NDemethylation signiˆcantly contributes to produce active metabolites in cases of ‰uoxetine (Fig. 1 (d)), ...
... artemether gives pharmacologically active O-desmethylvenlafaxine, O-desmethylivabradine and dihydroartemisinin, respectively.1921) Ivabradine also forms active metabolite by N-demethylation.20) NDemethylation signiˆcantly contributes to produce active metabolites in cases of ‰uoxetine (Fig. 1 (d)), ...
10.4103-0975-1483.93570
... concentration that lies between the minimum effect concentration (MEC) and minimum toxic concentration (MTC). Cephalexin is a semisynthetic antibiotic derived from cephalosporin C and is almost completely absorbed from the gastrointestinal tract with a bioavailability of 95%. Cephalexin has a half l ...
... concentration that lies between the minimum effect concentration (MEC) and minimum toxic concentration (MTC). Cephalexin is a semisynthetic antibiotic derived from cephalosporin C and is almost completely absorbed from the gastrointestinal tract with a bioavailability of 95%. Cephalexin has a half l ...
Pharmacology of Vasoconstrictors
... surgical area; this amount of epinephrine is not used for block anesthesia ...
... surgical area; this amount of epinephrine is not used for block anesthesia ...
Lufenuron Mode Of Action
... in treated dogs with high microfilaremia counts (see Precautions for reactions observed). Safety studies in pregnant dogs demonstrated that high doses (1.5 mg/kg = 3X) of milbemycin oxime given in an exaggerated dosing regimen (daily from mating through weaning), resulted in measurable concentration ...
... in treated dogs with high microfilaremia counts (see Precautions for reactions observed). Safety studies in pregnant dogs demonstrated that high doses (1.5 mg/kg = 3X) of milbemycin oxime given in an exaggerated dosing regimen (daily from mating through weaning), resulted in measurable concentration ...
Protocol S1.
... Human glucocerebrosidase has been used successfully for the clinical treatment of Gaucher disease for several years from both natural and recombinant sources (CHO production platform). This is the first trial to utilize a recombinant active form of lysosomal enzyme, glucocerebrosidase, (human prGCD) ...
... Human glucocerebrosidase has been used successfully for the clinical treatment of Gaucher disease for several years from both natural and recombinant sources (CHO production platform). This is the first trial to utilize a recombinant active form of lysosomal enzyme, glucocerebrosidase, (human prGCD) ...
Using Opioids for Pain
... Short acting oral opioids can be titrated quickly- dose by dose. Sustained release oral opioids can be dose-escalated every 24-72 hrs. Transdermal fentanyl should not be dose escalated more often than every 72 hrs. Methadone should not be titrated more often than every 5-7 days. ...
... Short acting oral opioids can be titrated quickly- dose by dose. Sustained release oral opioids can be dose-escalated every 24-72 hrs. Transdermal fentanyl should not be dose escalated more often than every 72 hrs. Methadone should not be titrated more often than every 5-7 days. ...
APPLICATION OF UV SPECTROPHOTOMETRIC METHODS FOR ESTIMATION OF
... were 280.0 nm (λmax of CIP) and 310.0 nm (λmax of TIN), and in Q analysis wavelengths selected for analysis were 291.0 nm (isobestic point) and 310.0 nm (λmax of TIN) The method linearity for detector response was observed in the concentration range of 2-16 μg/ml for both CIP and TIN. Absorptive coe ...
... were 280.0 nm (λmax of CIP) and 310.0 nm (λmax of TIN), and in Q analysis wavelengths selected for analysis were 291.0 nm (isobestic point) and 310.0 nm (λmax of TIN) The method linearity for detector response was observed in the concentration range of 2-16 μg/ml for both CIP and TIN. Absorptive coe ...
SPECTROPHOTOMETRIC DETERMINATION OF PENEMS IN BULK AND INJECTION
... Three simple and cost effective spectrophotometric methods were described for the determination of Imipenem, Meropenem and Biapenem in pure form and in pharmaceutical formulations. The method is based on the formation of blue colored chromogen when the drug reacts with Potassium ferri cyanide reagen ...
... Three simple and cost effective spectrophotometric methods were described for the determination of Imipenem, Meropenem and Biapenem in pure form and in pharmaceutical formulations. The method is based on the formation of blue colored chromogen when the drug reacts with Potassium ferri cyanide reagen ...
SIMPLE AND SELECTIVE SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF
... But, incase of method C the highest absorbance and reproducible value were obtained when methanol was used as a diluting solvent. Effects of reaction time and temperature The colored dyes developed rapidly after the addition of reagents and attained maximum intensity after about 5 min at room temper ...
... But, incase of method C the highest absorbance and reproducible value were obtained when methanol was used as a diluting solvent. Effects of reaction time and temperature The colored dyes developed rapidly after the addition of reagents and attained maximum intensity after about 5 min at room temper ...
Development and validation of desvenlafaxine succinate in bulk an
... accurately weighed and transferred into a 100ml volumetric flask. This was dissolved in distilled water and volume was made up to 100ml to give standard stock solution of 1000µg/ml. To 1ml tablet stock solution in 3 different volumetric flask, aliquots of 0.8 ml, 1ml and 1.2ml of standard stock solu ...
... accurately weighed and transferred into a 100ml volumetric flask. This was dissolved in distilled water and volume was made up to 100ml to give standard stock solution of 1000µg/ml. To 1ml tablet stock solution in 3 different volumetric flask, aliquots of 0.8 ml, 1ml and 1.2ml of standard stock solu ...
Interactions with Drugs and Dietary Supplements Used
... in waist circumference, blood pressure, and blood glucose and lipid profiles [71-73]. A large number of preclinical and clinical studies and case reports related to potential drug interactions with orlistat have been published. There have been several cases of orlistat interaction with cyclosporine ...
... in waist circumference, blood pressure, and blood glucose and lipid profiles [71-73]. A large number of preclinical and clinical studies and case reports related to potential drug interactions with orlistat have been published. There have been several cases of orlistat interaction with cyclosporine ...
10. review of literature
... 2.1.1. Garg et al., 2012 have developed asymmetric membrane capsules (AMCs) with two compartments for simultaneous delivery of two poorly water-soluble drugs, Atenolol and Amlodipine Besylate, by using solubility modulation approach. Scanning electron microscopy (SEM) before dissolution showed prese ...
... 2.1.1. Garg et al., 2012 have developed asymmetric membrane capsules (AMCs) with two compartments for simultaneous delivery of two poorly water-soluble drugs, Atenolol and Amlodipine Besylate, by using solubility modulation approach. Scanning electron microscopy (SEM) before dissolution showed prese ...
FORMULATION, EVALUATION AND OPTIMIZATION OF SOLID DISPERSION OF GLIPIZIDE
... of 2-4 hrs. Glipizide is reported to have a short biological half life (3.4 ± 0.7 h) requiring it to be administered in 2 to 3 doses of 2.5 to 10 mg per day 11. High hydrophobicity and hence poor aqueous solubility of Glipizide leads to inadequate dissolution in gastrointestinal (GI) fluids and henc ...
... of 2-4 hrs. Glipizide is reported to have a short biological half life (3.4 ± 0.7 h) requiring it to be administered in 2 to 3 doses of 2.5 to 10 mg per day 11. High hydrophobicity and hence poor aqueous solubility of Glipizide leads to inadequate dissolution in gastrointestinal (GI) fluids and henc ...
DESIGN, DEVELOPMENT AND OPTIMIZATION OF FAST DISSOLVING TABLET OF
... induced emesis. The adult dose is 8 mg and its metabolites are excreted in urine with about 10% of unchanged drug and having 67% of bioavailability through oral route. In the present investigation FDT of Ondansetron HCl was developed by maximizing the porous structure of the tablet matrix, incorpora ...
... induced emesis. The adult dose is 8 mg and its metabolites are excreted in urine with about 10% of unchanged drug and having 67% of bioavailability through oral route. In the present investigation FDT of Ondansetron HCl was developed by maximizing the porous structure of the tablet matrix, incorpora ...
ION ASSOCIATION METHOD FOR THE DETERMINATION OF SUMATRIPTAN SUCCINATE FROM TABLET DOSAGE FORMS USING TROPAEOLIN OOO
... A simple, sensitive, rapid and accurate extractive spectrophotometric method has been developed for the determination of sumatriptan succinate from bulk and tablet dosage forms. The method is based on the formation of orange red colored chloroform extractable ion‐pair complex between the basic ni ...
... A simple, sensitive, rapid and accurate extractive spectrophotometric method has been developed for the determination of sumatriptan succinate from bulk and tablet dosage forms. The method is based on the formation of orange red colored chloroform extractable ion‐pair complex between the basic ni ...
CEIBA PENTANDRA AND THEIR COMBINATION ON DEXAMETHASONE INDUCED DIABETIC SWISS ALBINO RATS VIRIDIS
... not produce hypoglycaemic activity. It means that the ethanolic extract of Amaranthus viridis and Ceiba pentandra and its combination do not influence normal blood glucose levels of individuals. The mechanism of action of these plant extracts may be similar to that metformin. Both the standard and t ...
... not produce hypoglycaemic activity. It means that the ethanolic extract of Amaranthus viridis and Ceiba pentandra and its combination do not influence normal blood glucose levels of individuals. The mechanism of action of these plant extracts may be similar to that metformin. Both the standard and t ...
