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Logarithms and Savings Accounts
Logarithms and Savings Accounts

... We had previously asked the question, “How long will it take for the number of cells in the dish to reach 3000?” Originally solved by setting up a table in Excel and found that after 69 minutes, there were 2898 cells and at 70 minutes, there were 3043 cells. Obviously somewhere between minute 69 and ...
Cl = Vd x 0T693
Cl = Vd x 0T693

NEW VALIDATED RP–HPLC METHOD FOR THE ESTIMATION OF CARVEDILOL IN
NEW VALIDATED RP–HPLC METHOD FOR THE ESTIMATION OF CARVEDILOL IN

... pre-analyzed tablet solution. Percent recovery was calculated by comparing the area before and after the addition of the standard drug. The standard addition method was performed at 50%, 100% and 150% level of40ppm. The solutions were analyzed in triplicate at each level as per the proposed method. ...
Running head: PERSONAL DRUGS PERSONAL DRUGS Personal
Running head: PERSONAL DRUGS PERSONAL DRUGS Personal

... leukopenia, neutropenia, seizure, thrombocytopenia Monitor: Renal, hepatic, and hematologic function with long term use ...
The PENTRA®Body Company
The PENTRA®Body Company

... • Chronic inflammatory disease that affects apocrine-glandbearing body areas such as the axilla or the ano-genital region • No effective treatment is available, medical need is high • Hurley Stages I and II most often require oral antibiotic therapy for up to 12 weeks, stage III requires surgery • A ...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF DONEPEZIL HYDROCHLORIDE  TABLETS BY RP­HPLC  Research Article  T. SENTHIL KUMAR
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF DONEPEZIL HYDROCHLORIDE  TABLETS BY RP­HPLC  Research Article  T. SENTHIL KUMAR

... of  the  peak  area  and  determination  of  the  RSD  (%)  of  all  injections.  The  RSD  (%)  value  obtained  was  below  1,  which  indicated the precision of the method. The Intra assay precision,  mean  %  recovery  and  %  RSD  are  0.2034,  100.37  ±  0.147  and  0.146 respectively.   There ...
Interactions between Grapefruit Juice and Calcium Channel
Interactions between Grapefruit Juice and Calcium Channel

DESIGNING AND COMPUTATIONAL STUDY OF SOME NOVEL LAMIVUDINE ANALOGUES AS
DESIGNING AND COMPUTATIONAL STUDY OF SOME NOVEL LAMIVUDINE ANALOGUES AS

... we modeled three new analogs of lamivudine. The drug likeness and molecular properties of the analogs are analyzed and further used in docking studies. The structure of a catalytic complex of HIV-1 reverse transcriptase is selected for performing the docking studies with the new analogs. Prior to do ...
sesame seeds - ENCOGNITIVE.COM
sesame seeds - ENCOGNITIVE.COM

Articaine: Efficacy and Paresthesia in Dental Local Anesthesia
Articaine: Efficacy and Paresthesia in Dental Local Anesthesia

... respectively.13 Articaine is excreted primarily through urine, with 53-57% of the administered dose eliminated in 24 hours.13 Reports of systemic toxic effects following the use of articaine for dental anesthesia are extremely difficult to find. Although marketed as a 4% solution, the rapid inactiva ...
PHYSICOCHEMICAL CHARACTERIZATION AND IN-VITRO DISSOLUTION BEHAVIOR OF GLICLAZIDE –SOLUPLUS SOLID DISPERSIONS
PHYSICOCHEMICAL CHARACTERIZATION AND IN-VITRO DISSOLUTION BEHAVIOR OF GLICLAZIDE –SOLUPLUS SOLID DISPERSIONS

... polymers that possess high melting points or Tg values [14], soluplus is a polyvinyl caprolactum (57%)-polyvinyl acetate (30%)poly ethylene glycol (PEG 6000-13%) graft co-polymer. It is a polymeric solubilizer with an amphiphilic chemical structure and due to its bi functional characters it is able ...
Vitamin D dosing for vitamin D deficiency?
Vitamin D dosing for vitamin D deficiency?

... maintenance therapy. Where correction of vitamin D deficiency is less urgent and when coprescribing vitamin D supplements with an oral antiresorptive agent, maintenance therapy may be started without the use of loading doses (4). Annual depot vitamin D therapy either by IM injection or orally and us ...
- Wiley Online Library
- Wiley Online Library

... effects of NSAIDs are limited because most inflammation models do not permit pharmacokinetic/ pharmacodynamic (PK/PD) modelling to be readily performed. 2 In this study, a kaolin-induced inflammation model in the cat was evaluated for pre-clinical characterization of the pharmacodynamic profiles of ...
Effects of High and Low Molecular Weight Chitosan on Plasma
Effects of High and Low Molecular Weight Chitosan on Plasma

... and develop hypoinsulinemia and high blood glucose similar to type 1 DM animals(17). Pretreatment of nicotinamide can scavenge free radicals and recruit the consumption of nicotinamide adenine dinucleotide (NAD+) in pancreatic β-cell after STZ injection. Hence the injection of nicotinamide can parti ...
Title of the Topic
Title of the Topic

... The carrot (Daucus carota) belongs to the family Apiaceae. The edible part of a carrot is a taproot. The carrot gets its characteristic and bright orange colour from β-carotene, which is metabolised into vitamin A in humans when bile salts are present in the intestines. Carrots are credited with ma ...
prediction of “first dose in human”
prediction of “first dose in human”

... Weight based allometric scaling was further examined for an atherosclerotic plaque targeted radiopharmaceutical imaging agent, RP845-Tc-99m, currently in development. Pharmacokinetic parameters were determined in mouse, rat and rabbit followed by allometric scaling to predict the non-human primate v ...
International Journal of Innovative Pharmaceutical Sciences and
International Journal of Innovative Pharmaceutical Sciences and

Testosterone and anabolic steroids
Testosterone and anabolic steroids

... The Canadian AIDS Treatment Information Exchange (CATIE) in good faith provides information resources to help people living with HIV/AIDS who wish to manage their own health care in partnership with their care providers. Information accessed through or published or provided by CATIE, however, is not ...
Vancomycin Dosing - CHW - The Children`s Hospital at Westmead
Vancomycin Dosing - CHW - The Children`s Hospital at Westmead

... Gonzalez C, Rubio M, Romero-Vivas J, Gonzalez M, Picazo JJ. Bacteremic pneumonia due to Staphylococcus aureus: A comparison of disease caused by methicillin-resistant and methicillinsusceptible organisms. Clin Infect Dis. 1999;29(5):1171-7. Rybak M, Lomaestro B, Rotschafer JC, Moellering R, Jr., Cra ...
Systemic effects of salbutamol and salmeterol in patients
Systemic effects of salbutamol and salmeterol in patients

Determination of levetiracetam in human plasma with minimal sample pretreatment Jens Martens-Lobenhoffer
Determination of levetiracetam in human plasma with minimal sample pretreatment Jens Martens-Lobenhoffer

... is very easy, quick and cheap compared with an extraction procedure. The protein precipitation with organic solvents like methanol or acetonitrile [7] has also a drawback, because a mixture rich in organic solvent is produced, which in the case of levetiracetam has a higher solvent strength than the ...
The Effects of Ibuprofen on the Embryological Development of
The Effects of Ibuprofen on the Embryological Development of

A VALIDATED ULTRA FAST LIQUID CHROMATOGRAPHY METHOD FOR ASSAY Research Article
A VALIDATED ULTRA FAST LIQUID CHROMATOGRAPHY METHOD FOR ASSAY Research Article

... short run time which supports to the process, cost reduction by reduced solvent consumption and less analysis time. The method is more precise and accurate through out its range with good separation between degradation products and omeprazole. RESULT AND DISCUSSION A reversed-phase chromatographic t ...
The pharmacokinetic profile of fesoterodine
The pharmacokinetic profile of fesoterodine

... 5-HMT and involvement of multiple metabolic and renal excretion pathways in the elimination of 5-HMT, the effects of patient-intrinsic and -extrinsic factors on the pharmacokinetics of fesoterodine are only modest, with some 2-fold higher 5-HMT exposure. Therefore, in contrast to tolterodine, no red ...
COMPARATIVE EVALUATION OF POTATO STARCH AND BANANA POWDER AS
COMPARATIVE EVALUATION OF POTATO STARCH AND BANANA POWDER AS

... The hardness values ranged from 5.6 to 6.1 kg/cm 2 for all formulations (Table 3). The entire tablets passes weight variation test as the average % weight variation was the pharmacopoeial limit of 5% (Table 3). The friability values were found to be within the limit (Table 3). The drug content of ac ...
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Plateau principle

The plateau principle is a mathematical model or scientific law originally developed to explain the time course of drug action The principle has wide applicability in pharmacology, physiology, nutrition, biochemistry and system dynamics. It applies whenever a drug or nutrient is infused or ingested at a relatively constant rate and when a constant fraction is eliminated during each time interval. Under these conditions, any change in the rate of infusion leads to an exponential increase or decrease until a new level is achieved. This behavior is also called an approach to steady state because rather than causing an indefinite increase or decrease, a natural balance is achieved when the rate of infusion or production is balanced by the rate of loss.An especially important use of the plateau principle is to study the renewal of tissue constituents in the human and animal body. In adults, daily synthesis of tissue constituents is nearly constant, and most constituents are removed with a first order reaction rate. Applicability of the plateau principle was recognized during radiotracer studies of protein turnover in the 1940s by Rudolph Schoenheimer and David Rittenberg. Unlike the case with drugs, the initial amount of tissue or tissue protein is not zero because daily synthesis offsets daily elimination. In this case, the model is also said to approach a steady state with exponential or logarithmic kinetics. Constituents that change in this manner are said to have a biological half-life.A practical application of the plateau principle is that most people have experienced ""plateauing"" during regimens for weight management or training for sports. After a few weeks of progress, one seems unable to continue gaining in ability or losing weight. This outcome results from the same underlying quantitative model. This entry will describe the popular concepts as well as development of the plateau principle as a scientific, mathematical model.In the sciences, the broadest application of the plateau principle is creating realistic time signatures for change in kinetic models (see Mathematical model). One example of this principle is the long time required to effectively change human body composition. Theoretical studies have shown that many months of consistent physical training and food restriction are needed to bring about permanent weight stability in people who were previously overweight.
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