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Genome-wide DNA methylation analysis
... of DNA involved in a variety of biological processes, including embryogenesis and development, silencing of transposable elements, regulation of gene transcription and tumorigenesis and progression. The methylation pattern of DNA is highly variable among cells ...
... of DNA involved in a variety of biological processes, including embryogenesis and development, silencing of transposable elements, regulation of gene transcription and tumorigenesis and progression. The methylation pattern of DNA is highly variable among cells ...
Microarray-based DNA methylation profiling: technology and
... various aspects of the technology including its replicability, informativeness, sensitivity and optimal PCR conditions using microarrays containing oligonucleotides representing 100 kb of genomic DNA derived from the chromosome 22 COMT region in addition to 12 192 element CpG island microarrays. Sev ...
... various aspects of the technology including its replicability, informativeness, sensitivity and optimal PCR conditions using microarrays containing oligonucleotides representing 100 kb of genomic DNA derived from the chromosome 22 COMT region in addition to 12 192 element CpG island microarrays. Sev ...
Effects of Salt Concentrations and Bending Energy on the Extent of
... For any lower value of cPEG there is a pressure difference and hence a net force (outward) on the confining walls, because an insufficient amount of water has been drawn out of the DNA solution to lower its hydrostatic pressure to 1 atm. Let cPEG be such an intermediate value: 0,cPEG ,cPEG . Suppos ...
... For any lower value of cPEG there is a pressure difference and hence a net force (outward) on the confining walls, because an insufficient amount of water has been drawn out of the DNA solution to lower its hydrostatic pressure to 1 atm. Let cPEG be such an intermediate value: 0,cPEG ,cPEG . Suppos ...
A Eukaryotic SWI2/SNF2 Domain, an Exquisite Detector of Double
... 6 ⫻ 10⫺27) and 30% identity over 289 amino acids of yeast Mot1 sequence (NCBI accession number P32333; BLASTP value: 2 ⫻ 10⫺17) (13). Although BLASTP demonstrated significant similarity of ATPase A to other Saccharomyces cerevisiae proteins such as the Snf2 and Sth1 proteins (14, 15), no S. cerevisi ...
... 6 ⫻ 10⫺27) and 30% identity over 289 amino acids of yeast Mot1 sequence (NCBI accession number P32333; BLASTP value: 2 ⫻ 10⫺17) (13). Although BLASTP demonstrated significant similarity of ATPase A to other Saccharomyces cerevisiae proteins such as the Snf2 and Sth1 proteins (14, 15), no S. cerevisi ...
Slide 1
... Chapter 13 Genetics and Biotechnology Section 1: Applied Genetics Section 2: DNA Technology Section 3: The Human Genome ...
... Chapter 13 Genetics and Biotechnology Section 1: Applied Genetics Section 2: DNA Technology Section 3: The Human Genome ...
Van, C., Williams, J.S., Kunkel, T.A., and
... independent MMR. The SWR-C-dependent incorporation of H2A.Z into chromatin may facilitate this MMR pathway. Given the need to coordinate nuclear DNA replication with the action of multiple histone chaperones ahead of and behind the replication fork and with multiple ATP-dependent chromatin remodelin ...
... independent MMR. The SWR-C-dependent incorporation of H2A.Z into chromatin may facilitate this MMR pathway. Given the need to coordinate nuclear DNA replication with the action of multiple histone chaperones ahead of and behind the replication fork and with multiple ATP-dependent chromatin remodelin ...
Infectivity analysis of two variable DNA B components of Mungbean
... The KA27 DNA B component of MYMV-Vig was strikingly similar to the DNA B of MYMV (a mungbean isolate from Thailand) (Morinaga et al 1993) on the basis of overall nucleotide sequence identity, CR organization, BV1 and BC1 amino acid sequences and in NLS and NES motifs. ...
... The KA27 DNA B component of MYMV-Vig was strikingly similar to the DNA B of MYMV (a mungbean isolate from Thailand) (Morinaga et al 1993) on the basis of overall nucleotide sequence identity, CR organization, BV1 and BC1 amino acid sequences and in NLS and NES motifs. ...
Molecular Basis of Heredity--ST03 1.2.7
... concern of his parents when Julie was younger, especially before some sort of "treatment" that accelerated her growth had begun. When the teacher assigned oral reports to be given on various human defects, Terry resolved to do one on "whatever Julie has." The teacher accepted this, but cautioned tha ...
... concern of his parents when Julie was younger, especially before some sort of "treatment" that accelerated her growth had begun. When the teacher assigned oral reports to be given on various human defects, Terry resolved to do one on "whatever Julie has." The teacher accepted this, but cautioned tha ...
Chapter 12
... A crime has been committed and you have a suspect as well as a tiny bit of DNA sample from the scene of the crime. What do you do? The first thing you do is PCR the DNA to make more copies of it… ...
... A crime has been committed and you have a suspect as well as a tiny bit of DNA sample from the scene of the crime. What do you do? The first thing you do is PCR the DNA to make more copies of it… ...
Application of a Real Time Polymerase Chain Reaction Method to
... of UV-absorbing contaminants, such as protein. The CTAB extraction method yielded a higher concentration of DNA (22 and 12 ng/µL from milk and egg, respectively), with acceptable DNA purity (A260/A280 was 1.8 for both matrixes) (Table 1). The quantity and quality of DNA was also evaluated via the SY ...
... of UV-absorbing contaminants, such as protein. The CTAB extraction method yielded a higher concentration of DNA (22 and 12 ng/µL from milk and egg, respectively), with acceptable DNA purity (A260/A280 was 1.8 for both matrixes) (Table 1). The quantity and quality of DNA was also evaluated via the SY ...
unit II - SP College
... Satellite DNA adopts higher-order three-dimensional structures in eukaryotic organisms. This was demonstrated in the land crab Gecarcinuslateralis, whose DNA contains 3% of a GC-rich sequence consisting of repeats of a ~2100 base pair (bp) sequence called RU. The RU was arranged in long tandem array ...
... Satellite DNA adopts higher-order three-dimensional structures in eukaryotic organisms. This was demonstrated in the land crab Gecarcinuslateralis, whose DNA contains 3% of a GC-rich sequence consisting of repeats of a ~2100 base pair (bp) sequence called RU. The RU was arranged in long tandem array ...
Extrachromosomal DNA Transformationof Caenorhabditis elegans
... foreign DNA sequences in the transformed worm cells were measured by quantitative hybridization analysis. DNA preparations from transformed populations were spotted onto triplicate nitrocellulose filters. The filters were hybridized with 32P-labeled pBR322 DNA, bacteriophage DNA containing a single- ...
... foreign DNA sequences in the transformed worm cells were measured by quantitative hybridization analysis. DNA preparations from transformed populations were spotted onto triplicate nitrocellulose filters. The filters were hybridized with 32P-labeled pBR322 DNA, bacteriophage DNA containing a single- ...
View/Open
... DNA matching. Studying the structure of genes and DNA, scientists can determine genetic relationships between different species (and hence the course of evolution) or between people. They can also identify the remains of individuals through DNA matching, a valuable tool if there are no other physi ...
... DNA matching. Studying the structure of genes and DNA, scientists can determine genetic relationships between different species (and hence the course of evolution) or between people. They can also identify the remains of individuals through DNA matching, a valuable tool if there are no other physi ...
University of Groningen DNA Block Copolymers Schnitzler
... e live in a world full of synthetic materials, and the development of new technologies builds on the design and synthesis of new chemical structures, such as polymers. Synthetic macromolecules have changed the world and currently play a major role in all aspects of daily life. Due to their tailorabl ...
... e live in a world full of synthetic materials, and the development of new technologies builds on the design and synthesis of new chemical structures, such as polymers. Synthetic macromolecules have changed the world and currently play a major role in all aspects of daily life. Due to their tailorabl ...
Soliton-like base pair opening in a helicoidal DNA: An analogy with
... Similar results have also been observed by Dauxios [10] through a perturbation analysis on his helicoidal model of DNA and obtained soliton with a much broader width. In order to have a more realistic model, dissipative (viscous effect) and noise terms should be added to the equations of motion. Exp ...
... Similar results have also been observed by Dauxios [10] through a perturbation analysis on his helicoidal model of DNA and obtained soliton with a much broader width. In order to have a more realistic model, dissipative (viscous effect) and noise terms should be added to the equations of motion. Exp ...
A systematic search for DNA methyltransferase polymorphisms
... between polymorphisms and DNA methylation values at these loci were observed. This was true for both allele-based and genotype-based association analysis (Supplementary Material, Tables S2 and 3). We then asked whether a given extended haplotype (Supplementary Material, Table S4) over an entire gene ...
... between polymorphisms and DNA methylation values at these loci were observed. This was true for both allele-based and genotype-based association analysis (Supplementary Material, Tables S2 and 3). We then asked whether a given extended haplotype (Supplementary Material, Table S4) over an entire gene ...
Inheritance of Organelle DNA Sequences in a Citrus–Poncirus
... trifoliata mtDNA configurations suggested that these configurations resulted from influence of the nuclear genome. Nuclear alleles might alter mtDNA organization in the progeny, producing P. trifoliata configurations. Alternatively, the P. trifoliata mtDNA configurations observed in the progeny migh ...
... trifoliata mtDNA configurations suggested that these configurations resulted from influence of the nuclear genome. Nuclear alleles might alter mtDNA organization in the progeny, producing P. trifoliata configurations. Alternatively, the P. trifoliata mtDNA configurations observed in the progeny migh ...
Inheritance of Nuclear DNA Markers in Gynogenetic Haploid Pink
... diploid and haploid progeny that provide more powerful methods of genetic analysis ( Thorgaard and Allen 1987). Examination of gynogenetic haploids provides an efficient system to test for Mendelian segregation and linkage without the complications associated with diploidy and heterozygosity. For ex ...
... diploid and haploid progeny that provide more powerful methods of genetic analysis ( Thorgaard and Allen 1987). Examination of gynogenetic haploids provides an efficient system to test for Mendelian segregation and linkage without the complications associated with diploidy and heterozygosity. For ex ...
in Next Generation SNP Analysis: Future of Forensic Phenotyping
... To date, a great deal of study has been done on IISNPs. IISNPs serve the same purpose as the STRs. These SNPs are able to provide genetic information to differentiate between two individuals and exclude those who are not the source of the evidentiary DNA sample at a crime scene. To date, between 21 ...
... To date, a great deal of study has been done on IISNPs. IISNPs serve the same purpose as the STRs. These SNPs are able to provide genetic information to differentiate between two individuals and exclude those who are not the source of the evidentiary DNA sample at a crime scene. To date, between 21 ...
Activity Name - Science4Inquiry.com
... DNA Replication Assessment 1. Which of the following accurately reflects the correct order of DNA replication? a. Primase creates an RNA primer, helicase unzips the DNA, DNA polymerase adds nucleotides and creates new DNA, DNA polymerase fills in the gaps, DNA ligase seals the fragments of DNA, exon ...
... DNA Replication Assessment 1. Which of the following accurately reflects the correct order of DNA replication? a. Primase creates an RNA primer, helicase unzips the DNA, DNA polymerase adds nucleotides and creates new DNA, DNA polymerase fills in the gaps, DNA ligase seals the fragments of DNA, exon ...
Chapter 9 - People Server at UNCW
... • Used E.coli bacteria infected with a virus that consisted of a protein head surrounding DNA • Grew a batch of virus in a medium containing 35S and 32P • Blender experiments showed that the virus transfers DNA, not protein, into a bacterial cell • Thus, DNA is the genetic material ...
... • Used E.coli bacteria infected with a virus that consisted of a protein head surrounding DNA • Grew a batch of virus in a medium containing 35S and 32P • Blender experiments showed that the virus transfers DNA, not protein, into a bacterial cell • Thus, DNA is the genetic material ...
Positional dependence of transcriptional inhibition by DNA torsional
... As a global reduction of RNA synthesis was expected on accumulation of DNA ( þ ) helical stress (Gartenberg and Wang, 1992), we used qRT–PCR to determine the absolute value of transcript levels in our strains, as well as to validate the differential response of the chromosome flanks uncovered by the ...
... As a global reduction of RNA synthesis was expected on accumulation of DNA ( þ ) helical stress (Gartenberg and Wang, 1992), we used qRT–PCR to determine the absolute value of transcript levels in our strains, as well as to validate the differential response of the chromosome flanks uncovered by the ...
Reflection on Lloyd/Rhind Genetics Unit First and Foremost
... you look, what blood type you have, even your tendency to get some diseases. It is found inside the nucleus in just about every single cell of your body. In this activity, you’ll break away the membrane around the cell and its nucleus so that you can see your very own DNA. ...
... you look, what blood type you have, even your tendency to get some diseases. It is found inside the nucleus in just about every single cell of your body. In this activity, you’ll break away the membrane around the cell and its nucleus so that you can see your very own DNA. ...
Distinct mechanisms of DNA repair in mycobacteria - MCBL
... leprosy. It is estimated that about a third of the human population may be latently infected with Mycobacterium tuberculosis resulting in two million deaths annually (Dye et al., 1999). The biological niche of the pathogenic mycobacteria is the host macrophages. Pathogen’s ability to sustain within ...
... leprosy. It is estimated that about a third of the human population may be latently infected with Mycobacterium tuberculosis resulting in two million deaths annually (Dye et al., 1999). The biological niche of the pathogenic mycobacteria is the host macrophages. Pathogen’s ability to sustain within ...
DNA profiling
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DNA profiling (also called DNA fingerprinting, DNA testing, or DNA typing) is a forensic technique used to identify individuals by characteristics of their DNA. A DNA profile is a small set of DNA variations that is very likely to be different in all unrelated individuals, thereby being as unique to individuals as are fingerprints (hence the alternate name for the technique). DNA profiling should not be confused with full genome sequencing. First developed and used in 1985, DNA profiling is used in, for example, parentage testing and criminal investigation, to identify a person or to place a person at a crime scene, techniques which are now employed globally in forensic science to facilitate police detective work and help clarify paternity and immigration disputes.Although 99.9% of human DNA sequences are the same in every person, enough of the DNA is different that it is possible to distinguish one individual from another, unless they are monozygotic (""identical"") twins. DNA profiling uses repetitive (""repeat"") sequences that are highly variable, called variable number tandem repeats (VNTRs), in particular short tandem repeats (STRs). VNTR loci are very similar between closely related humans, but are so variable that unrelated individuals are extremely unlikely to have the same VNTRs.The DNA profiling technique nowadays used is based on technology developed in 1988.