3D DNA Crystals and Nanotechnology
... crystallography began to reveal the structural and functional details of proteins, but nucleic acid crystal structures were largely limited to relatively simple dinucleoside phosphate structures [3], primarily owing to the expense of longer oligonucleotides of discrete sequences needed for crystalli ...
... crystallography began to reveal the structural and functional details of proteins, but nucleic acid crystal structures were largely limited to relatively simple dinucleoside phosphate structures [3], primarily owing to the expense of longer oligonucleotides of discrete sequences needed for crystalli ...
The Co-Evolution of Genes and Culture Pedigrees and the
... lactose tolerant. They can also be referred to as being lactase persistent, meaning that lactase production persists beyond childhood. (People who no longer produce lactase as adults are called lactase nonpersistent.) Genetic studies suggest that lactose tolerance arose among human populations in th ...
... lactose tolerant. They can also be referred to as being lactase persistent, meaning that lactase production persists beyond childhood. (People who no longer produce lactase as adults are called lactase nonpersistent.) Genetic studies suggest that lactose tolerance arose among human populations in th ...
functional analysis of chromatin assembly genes in tetrahymena
... The basic structural unit of chromatin is the nucleosome composed of ~147 base pairs of DNA wrapped around an octamer of histone proteins. Post-translational modifications such as histone acetylation or the substitution of histone variants in place of core histones have been implicated in various ch ...
... The basic structural unit of chromatin is the nucleosome composed of ~147 base pairs of DNA wrapped around an octamer of histone proteins. Post-translational modifications such as histone acetylation or the substitution of histone variants in place of core histones have been implicated in various ch ...
Indirect Recognition in Sequence
... around the protein, producing a bend of 180°. Bending plays an architectural role in the primary role for IHF in chromosome condensation (3). However, unlike other class members that exhibit no sequence specificity in DNA binding, IHF also binds in a sequence-specific manner to sites at which bendin ...
... around the protein, producing a bend of 180°. Bending plays an architectural role in the primary role for IHF in chromosome condensation (3). However, unlike other class members that exhibit no sequence specificity in DNA binding, IHF also binds in a sequence-specific manner to sites at which bendin ...
Enzyme Mechanisms - Illinois Institute of Technology
... Laser fluorescence detection allows for primer identification in real time An automated sequencing machine can handle 4500 bases/hour That’s one of the technologies that has made large-scale sequencing projects like the human genome project possible ...
... Laser fluorescence detection allows for primer identification in real time An automated sequencing machine can handle 4500 bases/hour That’s one of the technologies that has made large-scale sequencing projects like the human genome project possible ...
Detection and identification of bacteria in clinical samples by 16S
... ethanol precipitation method to remove unincorporated reagents and ensure a neutral charge. Briefly, sequencing products were washed in 80 ml ethanol precipitation mix (3 ml NaAc, 62.5 ml 95 % ethanol and 14.5 ml water) and the DNA was pelleted by centrifugation (13 000 g, 15 min). The pellet was ag ...
... ethanol precipitation method to remove unincorporated reagents and ensure a neutral charge. Briefly, sequencing products were washed in 80 ml ethanol precipitation mix (3 ml NaAc, 62.5 ml 95 % ethanol and 14.5 ml water) and the DNA was pelleted by centrifugation (13 000 g, 15 min). The pellet was ag ...
GENtle, a free multi-purpose molecular biology tool
... application of a patch-work of multiple, only partially compatible tools and web services. Commercial software often covers only parts of the required functions, and tends to lock the user into proprietary formats. In my thesis, I have developed GENtle, a free, multi-purpose bioinformatics software, ...
... application of a patch-work of multiple, only partially compatible tools and web services. Commercial software often covers only parts of the required functions, and tends to lock the user into proprietary formats. In my thesis, I have developed GENtle, a free, multi-purpose bioinformatics software, ...
The Sequence of the Gorilla Fetal Globin Genes
... ago, at least one gene conversion event occurred between these loci. This conversion occurred not long before the ancestral divergence (about 6 Myr ago) of Homo and Gorilla. After this ancestral divergence, a minimum of three more gene conversion events occurred in the human lineage. Each human ?-al ...
... ago, at least one gene conversion event occurred between these loci. This conversion occurred not long before the ancestral divergence (about 6 Myr ago) of Homo and Gorilla. After this ancestral divergence, a minimum of three more gene conversion events occurred in the human lineage. Each human ?-al ...
Final_peer-reviewed_manuscript - Research Explorer
... paper by Piet Borst and Leslie Grivell entitled ‘Small is Beautiful: Portrait of a Mitochondrial Genome’ (Borst and Grivell 1981). Borst and Grivell’s paper celebrates the major achievement of their colleagues and expresses the relevance of the genetic map for the field in more than scientific terms ...
... paper by Piet Borst and Leslie Grivell entitled ‘Small is Beautiful: Portrait of a Mitochondrial Genome’ (Borst and Grivell 1981). Borst and Grivell’s paper celebrates the major achievement of their colleagues and expresses the relevance of the genetic map for the field in more than scientific terms ...
Evaluation of Gene Structure Prediction Programs
... were 1410 sequences in this set. The integrity of the data set was further enforced by discarding the following sequences: the sequences whose protein coding segment did not start with the codon ATG (74 sequences), the sequences whose protein coding segment did not end with a stop codon (100 sequenc ...
... were 1410 sequences in this set. The integrity of the data set was further enforced by discarding the following sequences: the sequences whose protein coding segment did not start with the codon ATG (74 sequences), the sequences whose protein coding segment did not end with a stop codon (100 sequenc ...
The National DNA Database
... Act 1994, it has been overseen by a Management Board operated under a Memorandum of Understanding between the Forensic Science Service (FSS) and the Association of Chief Police Officers (ACPO). Recent developments, including the Home Office DNA Expansion Programme, the Review of the Forensic Science ...
... Act 1994, it has been overseen by a Management Board operated under a Memorandum of Understanding between the Forensic Science Service (FSS) and the Association of Chief Police Officers (ACPO). Recent developments, including the Home Office DNA Expansion Programme, the Review of the Forensic Science ...
Genetics - Michael
... crops and domesticated animals. In many early cultures, including those that were the precursors of some of today’s countries, the priests and royal families kept detailed records of lineages and bloodlines in order to establish a hierarchy of power. In the process, they also discovered that some tr ...
... crops and domesticated animals. In many early cultures, including those that were the precursors of some of today’s countries, the priests and royal families kept detailed records of lineages and bloodlines in order to establish a hierarchy of power. In the process, they also discovered that some tr ...
File S1 - Genetics
... subsequent labs as we try to characterize which genes are mutated in each strain. Background: Uses of mutants in genetic studies A. Forward and reverse genetics Analysis of mutants is the main tool used by a geneticists to understand how the information in DNA is translated into the phenotype. These ...
... subsequent labs as we try to characterize which genes are mutated in each strain. Background: Uses of mutants in genetic studies A. Forward and reverse genetics Analysis of mutants is the main tool used by a geneticists to understand how the information in DNA is translated into the phenotype. These ...
transposon
... types of transposon, with a total of several hundred individual elements. Transposable elements confer neither advantage nor disadvantage on the phenotype, but could constitute “selfish DNA,” concerned only with their own propagation. ...
... types of transposon, with a total of several hundred individual elements. Transposable elements confer neither advantage nor disadvantage on the phenotype, but could constitute “selfish DNA,” concerned only with their own propagation. ...
Identifikasi Molekular Bakteri Pathogen yang Menginfeksi Hama
... also exist within bacterial entomopathogen species and may have different pathogenic or virulence levels to the insect host. Therefore, rapid and accurate detection of bacteria is needed to differentiate them from others according to their role and to potentially use them as biological control. It h ...
... also exist within bacterial entomopathogen species and may have different pathogenic or virulence levels to the insect host. Therefore, rapid and accurate detection of bacteria is needed to differentiate them from others according to their role and to potentially use them as biological control. It h ...
Sleeping Beauty - Weber State University
... molecules bound per IR (Figure 3B, right panel), consistent with either two binding sites for the transposase within the IR or a transposase dimer bound to a single site. Transposase binding sites were further analyzed and mapped in a DNaseI footprinting experiment. Using the same fragment of T as a ...
... molecules bound per IR (Figure 3B, right panel), consistent with either two binding sites for the transposase within the IR or a transposase dimer bound to a single site. Transposase binding sites were further analyzed and mapped in a DNaseI footprinting experiment. Using the same fragment of T as a ...
DNA Identification Science: An Introduction for
... variation is easy to measure on an automated DNA sequencer. A forensic STR allele is a short DNA word (four or five letters long) that tandemly repeats a fixed number (e.g., 10 to 20) of times. More repeat units in an allele give greater DNA sentence length. For example, the D5S818 STR locus has the ...
... variation is easy to measure on an automated DNA sequencer. A forensic STR allele is a short DNA word (four or five letters long) that tandemly repeats a fixed number (e.g., 10 to 20) of times. More repeat units in an allele give greater DNA sentence length. For example, the D5S818 STR locus has the ...
Sequence requirements for function of the
... gene loci (Asano and Wharton, 1999; Calvi et al., 1998; Royzman et al., 1999). The data demonstrate that Drosophila chorion gene amplification uses evolutionarily conserved machinery for initiation; however, some mechanism must exist to uniquely mark the chorion gene loci origins for activation duri ...
... gene loci (Asano and Wharton, 1999; Calvi et al., 1998; Royzman et al., 1999). The data demonstrate that Drosophila chorion gene amplification uses evolutionarily conserved machinery for initiation; however, some mechanism must exist to uniquely mark the chorion gene loci origins for activation duri ...
Illustrating Python via Bioinformatics Examples
... Department of Informatics, University of Oslo ...
... Department of Informatics, University of Oslo ...
Unit 8 - OpenWetWare
... DNA Replication Each strand of the DNA double helix has all the information needed to reconstruct the other half by the mechanism of base pairing. In most prokaryotes, DNA replication begins at a single point and continues in two ...
... DNA Replication Each strand of the DNA double helix has all the information needed to reconstruct the other half by the mechanism of base pairing. In most prokaryotes, DNA replication begins at a single point and continues in two ...
DNA without Warrant - UR Scholarship Repository
... measurements and markings (height, weight, tattoos, palm prints, footprints), exemplars (handwriting, voice), biologics (blood, urine, saliva, and hair) and names (aliases). Around the corner, information gathering at arrest might include the modern digital wallet, compromising everything from passw ...
... measurements and markings (height, weight, tattoos, palm prints, footprints), exemplars (handwriting, voice), biologics (blood, urine, saliva, and hair) and names (aliases). Around the corner, information gathering at arrest might include the modern digital wallet, compromising everything from passw ...
9 Organization of the Human Genome Chapter 9
... the circle (in opposing directions for the two different strands), to generate large multigenic transcripts. The mature RNAs are subsequently generated by cleavage of the multigenic transcripts. Almost two-thirds (24 out of 37) of the mitochondrial genes specify a functional noncoding RNA as their fi ...
... the circle (in opposing directions for the two different strands), to generate large multigenic transcripts. The mature RNAs are subsequently generated by cleavage of the multigenic transcripts. Almost two-thirds (24 out of 37) of the mitochondrial genes specify a functional noncoding RNA as their fi ...
Microsatellite
A microsatellite is a tract of repetitive DNA in which certain DNA motifs (ranging in length from 2–5 base pairs) are repeated, typically 5-50 times. Microsatellites occur at thousands of locations in the human genome and they are notable for their high mutation rate and high diversity in the population. Microsatellites and their longer cousins, the minisatellites, together are classified as VNTR (variable number of tandem repeats) DNA. The name ""satellite"" refers to the early observation that centrifugation of genomic DNA in a test tube separates a prominent layer of bulk DNA from accompanying ""satellite"" layers of repetitive DNA. Microsatellites are often referred to as short tandem repeats (STRs) by forensic geneticists, or as simple sequence repeats (SSRs) by plant geneticists.They are widely used for DNA profiling in kinship analysis and in forensic identification. They are also used in genetic linkage analysis/marker assisted selection to locate a gene or a mutation responsible for a given trait or disease.