Presentation
... memory. It also can cause anxiety and altered perceptions (similar to but not quite the same as hallucinations). The most desirable effect of Ecstasy is its ability to provide feelings of warmth and empathy. Tell students that you will talk about the effects of Ecstasy in more detail in a few minute ...
... memory. It also can cause anxiety and altered perceptions (similar to but not quite the same as hallucinations). The most desirable effect of Ecstasy is its ability to provide feelings of warmth and empathy. Tell students that you will talk about the effects of Ecstasy in more detail in a few minute ...
LSD Fact Sheet - Drug Policy Alliance
... The risks associated with psychedelic drugs are mostly psychological, not physical. Physically, LSD is considered to be one of the least toxic drugs.xlii Although lethal doses have been determined from experiments in several animal models,xliii there has never been a recorded case of death exclusive ...
... The risks associated with psychedelic drugs are mostly psychological, not physical. Physically, LSD is considered to be one of the least toxic drugs.xlii Although lethal doses have been determined from experiments in several animal models,xliii there has never been a recorded case of death exclusive ...
PDF, 288KB - Queensland Courts
... told Will he might need these at night. 40. The next morning on Saturday the 18 June, Margaret rang Jeannette and asked her whether she had given Will narcotics? Dr Tait told her that yes, she had and that she had explained this the previous night. 41. Dr Tait said to Margaret she had given Will sev ...
... told Will he might need these at night. 40. The next morning on Saturday the 18 June, Margaret rang Jeannette and asked her whether she had given Will narcotics? Dr Tait told her that yes, she had and that she had explained this the previous night. 41. Dr Tait said to Margaret she had given Will sev ...
RIVM rapport 370030002 Trends in drug substances detected in
... dietary supplements secretly containing sibutramine or designer analogues. Such adulterated dietary supplements are deliberately mislabelled products that claim to be ‘all natural’ yet contain pharmaceutical drug substances. Another trend observed is the increase in counterfeit weight-loss medicines ...
... dietary supplements secretly containing sibutramine or designer analogues. Such adulterated dietary supplements are deliberately mislabelled products that claim to be ‘all natural’ yet contain pharmaceutical drug substances. Another trend observed is the increase in counterfeit weight-loss medicines ...
PIRACETAM ñ AN OLD DRUG WITH NOVEL PROPERTIES?
... plasma membrane. It would seem that they act as potentiators of an already present activity, rather than possessing any neurotransmitter-like activity of their own (12). Thus, piracetam is not prone to the often serious side effects of drugs which directly amplify or inhibit neurotransmitter action, ...
... plasma membrane. It would seem that they act as potentiators of an already present activity, rather than possessing any neurotransmitter-like activity of their own (12). Thus, piracetam is not prone to the often serious side effects of drugs which directly amplify or inhibit neurotransmitter action, ...
Homebrew equipoise 200mg/ml for Muscle Builing Boldenone
... In the veterinary feild Equipoise is most commonly used on horses, exhibiting a pronounced effect on lean bodyweight, appetite and general disposition of the animal. As with all steroids, this compound shows a marked ability for increasing red blood cell production. In recent years this compound has ...
... In the veterinary feild Equipoise is most commonly used on horses, exhibiting a pronounced effect on lean bodyweight, appetite and general disposition of the animal. As with all steroids, this compound shows a marked ability for increasing red blood cell production. In recent years this compound has ...
Biochemical Toxicity Induced By Tramadol
... and renal damage and sexual dysfunction. Tramadol toxic effects should be kept in mind during long term therapy specially in large doses. ...
... and renal damage and sexual dysfunction. Tramadol toxic effects should be kept in mind during long term therapy specially in large doses. ...
Neurochemical Enhancement of Conscious Error Awareness
... response inhibition paradigm, was administered to assess the influence of monoaminergic agents on performance errors during fMRI data acquisition. A single dose of methylphenidate, but not atomoxetine or citalopram, significantly improved the ability of healthy volunteers to consciously detect perfo ...
... response inhibition paradigm, was administered to assess the influence of monoaminergic agents on performance errors during fMRI data acquisition. A single dose of methylphenidate, but not atomoxetine or citalopram, significantly improved the ability of healthy volunteers to consciously detect perfo ...
Protective Effects of Beeswax Alcohols (D
... Gastric ulcers may arise frequently due to the chronic use of external aggressive factors, such as NSAIDs, stress, smoking, and alcohol consumption20. Nowadays, drug-induced damage to the gastrointestinal tract has become a health problem, in great part due to the extensive use of NSAIDs 2, whic ...
... Gastric ulcers may arise frequently due to the chronic use of external aggressive factors, such as NSAIDs, stress, smoking, and alcohol consumption20. Nowadays, drug-induced damage to the gastrointestinal tract has become a health problem, in great part due to the extensive use of NSAIDs 2, whic ...
HYPOTHESES 59
... sites, similarly to LSD (Pierce and Peroutka 1989; Deliganis et al. 1991), and is structurally similar to serotonin. Interestingly, DMT is known for its lack of psychoactivity when orally ingested, even in quantities in the order of grams (Ott 1999), due to metabolism by monoamine oxidase (MAO; Suzu ...
... sites, similarly to LSD (Pierce and Peroutka 1989; Deliganis et al. 1991), and is structurally similar to serotonin. Interestingly, DMT is known for its lack of psychoactivity when orally ingested, even in quantities in the order of grams (Ott 1999), due to metabolism by monoamine oxidase (MAO; Suzu ...
presentation source
... Is this a wonder drug, or are there side effects? • One side effect of Viagra comes from the relatively high selectivity for PDE 6. At peak plasma levels of Viagra, some subjects cannot distinguish between green and blue. • In placebo controlled studies, only 2.5% of users discontinued the use of V ...
... Is this a wonder drug, or are there side effects? • One side effect of Viagra comes from the relatively high selectivity for PDE 6. At peak plasma levels of Viagra, some subjects cannot distinguish between green and blue. • In placebo controlled studies, only 2.5% of users discontinued the use of V ...
NIH Public Access
... responding for nicotine (0.03 mg kg−1 per infusion) (Fig. 5a; Supplementary Fig. 14), further supporting a role for nicotine-induced activation of the IPN in restricting nicotine intake. Conversely, inactivation of the VTA profoundly decreased nicotine intake (0.03 mg kg−1 per infusion) (Supplementa ...
... responding for nicotine (0.03 mg kg−1 per infusion) (Fig. 5a; Supplementary Fig. 14), further supporting a role for nicotine-induced activation of the IPN in restricting nicotine intake. Conversely, inactivation of the VTA profoundly decreased nicotine intake (0.03 mg kg−1 per infusion) (Supplementa ...
Shilajit a materia medica monograph.
... human body with a significant number of additions in the reproductive and nervous system. The Ayurvedic energenics vary depending on the base rock that the shilajit comes from but it is generally thought to be tridoshic and only aggravating to Pitta (Fire) when used in excess. Clinical research conf ...
... human body with a significant number of additions in the reproductive and nervous system. The Ayurvedic energenics vary depending on the base rock that the shilajit comes from but it is generally thought to be tridoshic and only aggravating to Pitta (Fire) when used in excess. Clinical research conf ...
CURRICULUM VITAE Stacey C. Sigmon, Ph.D. February 2014
... substance use disorders: Trends in the literature. In P. Ruiz & E. Strain (Eds.), Lowinson & Ruiz’s Substance Abuse: A Comprehensive Textbook, Fifth Edition. Maryland: Lippincott Williams & Wilkins, pp. 603-621. (R) Sigmon, S.C. & Griffiths, R.R. (2011). Caffeine choice prospectively predicts positi ...
... substance use disorders: Trends in the literature. In P. Ruiz & E. Strain (Eds.), Lowinson & Ruiz’s Substance Abuse: A Comprehensive Textbook, Fifth Edition. Maryland: Lippincott Williams & Wilkins, pp. 603-621. (R) Sigmon, S.C. & Griffiths, R.R. (2011). Caffeine choice prospectively predicts positi ...
2. The contemporary drug problem: characteristics, patterns and
... (ATS), with some 33 million adults who used amphetamines, including methamphetamine, amphetamine and methcathinone, and about 20 million who used substances sold as “ecstasy” (MDMA). Cocaine and opiates were used by some 16 million and 17 million people respectively. Most of the opiate users, about ...
... (ATS), with some 33 million adults who used amphetamines, including methamphetamine, amphetamine and methcathinone, and about 20 million who used substances sold as “ecstasy” (MDMA). Cocaine and opiates were used by some 16 million and 17 million people respectively. Most of the opiate users, about ...
1 Name: Thyroglobulin (Proloid) Class: Thyroid Hormone Mech.: T3
... Class: Antithyroid Drug (Thioamide) Mech.: Blocks thyroid synthesis. Absorption: Oral → 80-95% bioavailability. Dist.: 80% protein binding. Poor placental transfer. 10% transfer into milk. Metab.: Conjugated to gluconamide. Excretion, t½: 35% excreted in urine, mostly as gluconamide. 1-2 hr. Toxicit ...
... Class: Antithyroid Drug (Thioamide) Mech.: Blocks thyroid synthesis. Absorption: Oral → 80-95% bioavailability. Dist.: 80% protein binding. Poor placental transfer. 10% transfer into milk. Metab.: Conjugated to gluconamide. Excretion, t½: 35% excreted in urine, mostly as gluconamide. 1-2 hr. Toxicit ...
Discriminative Stimulus Properties of MDMA
... unique and complex subjective effects which distinguish it from other recreationally used drugs. An understanding of the neurochemical mechanisms that underlie these effects is important in order to assess the potential for MDMA abuse and to inform researchers exploring of the drug’s therapeutic pot ...
... unique and complex subjective effects which distinguish it from other recreationally used drugs. An understanding of the neurochemical mechanisms that underlie these effects is important in order to assess the potential for MDMA abuse and to inform researchers exploring of the drug’s therapeutic pot ...
Subjects
... 13% of the total P450 content of the human liver (1,2). More than 20 clinically important drugs are partly or predominantly metabolized by this enzyme, including caffeine (2,3). CYP1A2 is also well known for its role in the metabolic activation of some environmental and food-borne carcinogens, inclu ...
... 13% of the total P450 content of the human liver (1,2). More than 20 clinically important drugs are partly or predominantly metabolized by this enzyme, including caffeine (2,3). CYP1A2 is also well known for its role in the metabolic activation of some environmental and food-borne carcinogens, inclu ...
Mephedrone
... nerve endings to an extent that was different from either drug alone. Mephedrone does not cause toxicity to 5HT nerve endings of the hippocampus. When co-administered with methamphetamine or MDMA toxicity is not increased as is the case for dopamine nerve endings when these drugs are taken together. ...
... nerve endings to an extent that was different from either drug alone. Mephedrone does not cause toxicity to 5HT nerve endings of the hippocampus. When co-administered with methamphetamine or MDMA toxicity is not increased as is the case for dopamine nerve endings when these drugs are taken together. ...
Drug-induced psychomimetic effects as a model for psychosis
... Europe -Figure 1- and as Thorazine in the United States), was synthesised in 1950 as an anaesthetic drug (Bennet, 1998). Its benefit in the treatment of psychosis was discovered in 1952, in the Parisian mental hospital Saint Anne (Delay et al., 1952a,b; Bennet, 1998; Kapur and Mamo, 2003). At the ti ...
... Europe -Figure 1- and as Thorazine in the United States), was synthesised in 1950 as an anaesthetic drug (Bennet, 1998). Its benefit in the treatment of psychosis was discovered in 1952, in the Parisian mental hospital Saint Anne (Delay et al., 1952a,b; Bennet, 1998; Kapur and Mamo, 2003). At the ti ...
Spice/K2 drugs – more than innocent substitutes for marijuana
... Synthetic agonists of cannabinoid receptors (hereafter ‘synthetic cannabimimetics’) represent a relatively new type of designer psychoactive drugs that has recently emerged on the recreational drug market (Fattore and Fratta, 2011; Zawilska, 2011; Winstock and Barratt, 2013). Smokeable herbal mixtur ...
... Synthetic agonists of cannabinoid receptors (hereafter ‘synthetic cannabimimetics’) represent a relatively new type of designer psychoactive drugs that has recently emerged on the recreational drug market (Fattore and Fratta, 2011; Zawilska, 2011; Winstock and Barratt, 2013). Smokeable herbal mixtur ...
Preparation and Characterisation of Mucoadhesive Nasal Gel of
... in terms of viscosity, texture profile analysis, ex vivo drug permeation profiles and histopathological studies. The results show that values of viscosity, hardness and adhesiveness increase while those of cohesiveness decrease with corresponding increase in concentration of the polymers. Ex vivo dr ...
... in terms of viscosity, texture profile analysis, ex vivo drug permeation profiles and histopathological studies. The results show that values of viscosity, hardness and adhesiveness increase while those of cohesiveness decrease with corresponding increase in concentration of the polymers. Ex vivo dr ...
Campus Location: Wilmington Effective Date: 2018
... List five routes of drug administration. List five rights of drug administration. List five factors that contribute to individual response to medication. Explain the concept of polypharmacy. ...
... List five routes of drug administration. List five rights of drug administration. List five factors that contribute to individual response to medication. Explain the concept of polypharmacy. ...
Antihistamines in pediatric allergy
... with placebo at therapeutic doses, but caused sedation when used off label at higher than recommended doses. In contrast, fexofenadine has been found to be free of sedative effects even at higher than therapeutic doses. Memory, attention and tracking performance were unaffected after administration ...
... with placebo at therapeutic doses, but caused sedation when used off label at higher than recommended doses. In contrast, fexofenadine has been found to be free of sedative effects even at higher than therapeutic doses. Memory, attention and tracking performance were unaffected after administration ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.