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Neuroscience of psychoactive substance use and dependence Neur
Neuroscience of psychoactive substance use and dependence Neur

... The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitat ...
Adolescence as a Unique Period of Vulnerability to Environmental
Adolescence as a Unique Period of Vulnerability to Environmental

... adolescents and adults in an animal model of anxiety known as Light-Enhanced Startle (LES). A brief overview and critique of current models of anxiety is presented below and is followed by discussion and predictions for the present experiment. Overview of Anxiety Paradigms Common methods for measuri ...
L-Tryptophan - Alternative Medicine Review
L-Tryptophan - Alternative Medicine Review

... Tryptophan’s primary mechanism of action is its role as the metabolic precursor of the neurotransmitter serotonin. Other neurotransmitters and central nervous system (CNS) chemicals, such as melatonin, dopamine, norepinephrine, and beta-endorphin, have also been shown to increase following oral admi ...
O A
O A

... cardiovascular system hyper activity such as increase of hart rate and hypertension. Benzodiazepines are one group of sedative-hypnotic drugs that used to reduce hallucination induced by KT. Midazolam is one of ultra short action benzodiazepines that be given intravenously in anesthesia. Midazolam, ...
Journal of Science  Chemistry IMPACT OF GIVING SILDENAFIL
Journal of Science Chemistry IMPACT OF GIVING SILDENAFIL

... disaggregatory actions of SNP both in vitro and ex vivo. The consequences of this antiplatelet action have been investigated. There was a trend to increased bleeding time in rat (60% increase not statistically significant, after 0.3 mg/kg i.v.) and bleeding time prolongation was seen in rabbits (129 ...
UTEROTONIC PROPERTIES OF NYMPHAEA ALBA ON ISOLATED MYOMETRIUM MODEL Original Article
UTEROTONIC PROPERTIES OF NYMPHAEA ALBA ON ISOLATED MYOMETRIUM MODEL Original Article

... (Nymphaeaceae) occurs in temperate and tropical regions. There are approximately 50species in this genus. Most are aquatic herbs, which are widely distributed in India, from Bengal, Orissa to Kashmir in lakes and ponds. The roots have also been used extensively in a variety of folk medicine. The dri ...
Epinephrine increases facility of outflow and cyclic AMP
Epinephrine increases facility of outflow and cyclic AMP

... cyclic AMP by a factor of 2.7 over control levels. After 90 min, cyclic AMP levels were increased 4.2 fold over control levels. Collectively, these results show that the intraocular pressure lowering effect of EPI in the human eye is mediated, at least in part, by an increase in facility of outflow. ...
The Effects of the Preferential 5
The Effects of the Preferential 5

... *Correspondence: Dr FX Vollenweider, University Hospital of ...
Traditional Indian spices and their health significance
Traditional Indian spices and their health significance

... effects on various chronic diseases. More rigorous clinical trials are needed to determine long-term benefits. The integration of knowledge is required to determine their effect in natural human settings. Turmeric, through its kaleidoscopic effects, appears to be truly a spice of life. Food based ap ...
Antidepressants for insomnia
Antidepressants for insomnia

... occurring in association with another disorder. However, most recent classification systems have moved away from this division as the distinction is now seen as unhelpful (Perlis 2010). The Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-V) recommends the use of the term ’i ...
Hepatotoxicity associated with illicit use of anabolic androgenic
Hepatotoxicity associated with illicit use of anabolic androgenic

... results in the production of RNA, DNA and the subsequent enhancement of protein synthesis (including increased amounts of actin and myosin in skeletal muscles) 2,9. The main chemical substitutions occurring to testosterone are the 17-beta-esterification and the 17alpha- alkylation. Whereas testoster ...
Antipsychotic Medication
Antipsychotic Medication

... vary considerably, must be adjusted as target symptoms change and side effects monitored Some patients begin to respond to sedating effects of typical drugs in 2-3 days, some take as long as 2 weeks Full benefits may take 4 or more weeks ...
Depressants Sedative Hypnotics
Depressants Sedative Hypnotics

... • Can significantly impair cognitive performance (especially memory) • Decreases academic performance • Reduces psychomotor functioning • Effects can occur for long periods after the drugs are discontinued • Impairments decrease over time (usually) ...
ADHD Doctor Discussion Guide
ADHD Doctor Discussion Guide

... • taking or has taken an anti-depression medicine called a monoamine oxidase inhibitor (MAOI) within the past 14 days. • sensitive or allergic to, or had a reaction to other stimulant medicines. Problems that can occur while taking Vyvanse. Tell the doctor: • if you or your child have heart problems ...
Hyperforin as a natural antidepressant: an overview
Hyperforin as a natural antidepressant: an overview

... research demonstrates that hyperforin - like many prescription antidepressants - inhibits the reuptake of the neurotransmitters norepinephrine, serotonin, and dopamine.2 All three of these compounds are naturally found in the brain and regulate mood and emotion. They are called “neurotransmitters” b ...
Benzodiazepine usage in the North Eastern Health Board
Benzodiazepine usage in the North Eastern Health Board

... characterised by anxiety, dysphoria, perceptual changes, headaches, muscle spasms and sleep disturbance. Other less common symptoms include seizures and episodes of confusion [3,4,5,16]. Abrupt withdrawal after long-term use can induce acute anxiety, psychosis and convulsions. Short-acting benzodiaz ...
"Marijuana - Not Just Blowing Smoke"
"Marijuana - Not Just Blowing Smoke"

... Portugal’s laws demonstrate another means of decriminalizing cannabis. Since 2001, it has been permitted for individuals to have up to an “average of a 10 day supply” of marijuana (or any other illicit drug, for that matter) in their possession for personal use only. [18] Possession of between a thr ...
Map and Application of States That Require a Prescription for
Map and Application of States That Require a Prescription for

... A material, compound, mixture, or preparation that contains any quantity of ephedrine, a salt of ephedrine, an optical isomer of ephedrine, or a salt of an optical isomer of ephedrine. Exempts products in solid oral dosage forms, including soft gelatin caplets, that combine 400 milligrams of guaifen ...
Map and Application of States That Require a Prescription for
Map and Application of States That Require a Prescription for

... A material, compound, mixture, or preparation that contains any quantity of ephedrine, a salt of ephedrine, an optical isomer of ephedrine, or a salt of an optical isomer of ephedrine. Exempts products in solid oral dosage forms, including soft gelatin caplets, that combine 400 milligrams of guaifen ...
SLEEP DISORDERS
SLEEP DISORDERS

... • Patient notices waking up unable to breathe or gasping for air ...
Adenosine
Adenosine

... Adenosine injection exerts its effect by decreasing conduction through the A-V node and may produce a short lasting first-, second- or third-degree heart block. Appropriate therapy should be instituted as needed. Patients who develop high-level block on one dose of adenosine should not be given addi ...
Cannabidiol: Pharmacology and potential therapeutic role
Cannabidiol: Pharmacology and potential therapeutic role

... The Cannabis genus of flowering plants mainly comprises the sativa and indica species. Indigenous to Central and South Asia, cannabis was used for millennia to produce hemp fiber for rope, clothing, bowstrings, and paper; for its seeds and seed oils; as livestock feed; and for medicine, religious ce ...
The Serotonin Syndrome - University of Colorado Denver
The Serotonin Syndrome - University of Colorado Denver

... 7349 persons and resulted in 93 deaths.8,9 The assessment of the serotonin syndrome in therapeutic drug dosing has relied on post-marketing surveillance studies, one of which identified an incidence of 0.4 case per 1000 patient-months for patients who were taking nefazodone.10 Performing a rigorous ...
JAP Mar. 86/3 - Journal of Applied Physiology
JAP Mar. 86/3 - Journal of Applied Physiology

... ANTITUSSIVE DRUGS, such as codeine and dextromethorphan, are among the most commonly used prescription and over-the-counter drugs in the world (12). These drugs are broadly classified into two groups based on their site of action: peripheral or central. Peripheral antitussive drugs act outside the c ...
PhD thesis
PhD thesis

... being exposed to relatively high levels of chemicals, but also the effects observed in the  normal population.  ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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