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101 Drugs - Academy of Wellness
101 Drugs - Academy of Wellness

... Chapter 2: Anti-Depressant Drugs There are a number of drug classes in the antidepressants. The most common are selective serotonin reuptake inhibitors (SSRIs). Serotonin is a chemical in the brain (neurotransmitter) that makes you feel happy. In people with depression, there is not enough of this ...
Understanding psychiatric medications: Benzodiazepines
Understanding psychiatric medications: Benzodiazepines

... benzodiazepines are felt within 30 minutes to four hours, depending on the type taken. With most benzodiazepines, the effects last several hours. When used appropriately, benzodiazepines are safe and effective drugs. They do, however, have potential for abuse and can be addictive. For this reason, t ...
Prozac Paper (Second Draft)
Prozac Paper (Second Draft)

... congener norfluoxetine selectively increase brain neurosteroid content at doses inadequate to inhibit serotonin reuptake. Pinna believes that fluoxetine’s pharmacologic actions would be described more accurately as a “selective brain steroidogenic stimulant.” This pharmacology is consistent with neu ...
Top 300 Drug List
Top 300 Drug List

... Many drug interactions, complicated by extremely long half life of 40-50 days. Hepatic and pulmonary damage possible; notify MD if jaundice, dark urine or trouble breathing occur. May cause thyroid problems, hypotension, bradycardia, ocular disease and exacerbate arrhythmia. Have regular ophthalmic ...
How long does liquid amoxicillin last
How long does liquid amoxicillin last

... have a very low shelf life that is of just 10 days , once the seal is broken. how long are amoxicillin pills good for . Sep 24, 2015. Discussion threads and articles about How Long Is Amoxicillin Good For. he wants to take the amoxicillin that's left, I want to know if it is safe for him to do this. ...
Inhaled phosphodiesterase type 5 inhibitors restore chloride transport in cystic fibrosis mice
Inhaled phosphodiesterase type 5 inhibitors restore chloride transport in cystic fibrosis mice

... delivered orally [2]. Nebulisation of topically active drugs has become increasingly common for treatment in CF [3]. Novel drug formulations acting through distinct mechanisms, including restoration of airway surface liquid or mucus, anti-inflammatory or anti-infective agents, and immunosuppressive ...
PDF - Journal of Applied Pharmaceutical Science
PDF - Journal of Applied Pharmaceutical Science

... Nasal mucosa has been considered as a potential ad-ministration route to achieve faster and higher level of drug absorption because it is permeable to more com-pounds than the gastrointestinal tract due to lack of pancreatic and gastric enzymatic activity, neutral pH of the nasal mucus and less dilu ...
Inhibition of Bladder Activity by 5 - Duke Statistical
Inhibition of Bladder Activity by 5 - Duke Statistical

... 5-HT1A agonist actions were mediated along the nociceptive afferent pathway as opposed to directly on the EUS motor neurons. These effects of 8-OH-DPAT treatment appear to be due to stimulation of 5-HT1A receptors on nociceptive C fibers or associated second-order neurons, since they played a signif ...
heroin - UNM Biology
heroin - UNM Biology

... Heroin is a narcotic analgesic derived from morphine. It is believed to be one of the most addictive drugs in the world today. For our group this topic was selected due to interest sparked by friends and family who have used and died from heroin as well as coming from a city and state that leads the ...
Appendix I  163
Appendix I 163

... about the number of sources involved. The only constraint implemented is that of maximal smoothness of the solution, based on the assumption that neighboring neuronal sources are likely to be similarly active (i.e., have similar orientations and strengths). The distribution obtained is thus the smoo ...
Insomnia Final - The Rx Consultant
Insomnia Final - The Rx Consultant

... asleep, or feel unrefreshed from sleep despite having adequate opportunity to sleep. Up to half of all adults complain of occasional trouble sleeping in any given year. About 10-25% have chronic symptoms with serious daytime consequences, including fatigue, difficulty concentrating, irritability, an ...
Nicotine Decreases Blood Alcohol
Nicotine Decreases Blood Alcohol

... behavior resulting from their co-usage. One interesting and unexpected discovery from our previous findings regarding the coexposure of alcohol and nicotine to neonatal rats is that the blood alcohol concentrations (BACs) were reduced in the presence of nicotine (Chen et al., 1998, 2001). The mechani ...
Effects of IV and ICV Hypocretin-1 (Orexin A)
Effects of IV and ICV Hypocretin-1 (Orexin A)

... emphasizing the need for developing more effective treatments. The major pathophysiology of human narcolepsy is now believed to be hypocretin deficiency.1-3 This discovery originated from observations in a canine model of the disorder and in preprohypocretin (preproorexin) knockout mice. Null mutati ...
LACTUCARIUM. LAPPA (Arctium lappa).
LACTUCARIUM. LAPPA (Arctium lappa).

... dyspepsia, acute hepatitis, acute duodenal catarrh, diarrhea of halfdigested aliment, muco-enteritis, and chronic enteritis. It will be evident from the guides given that leptandra, is a remedy for the complex known as “biliousness”. It aids chionanthus, and sometimes podophyllin to dissipate jaundi ...
Reinforcing behavioral variability: An analysis of dopamine
Reinforcing behavioral variability: An analysis of dopamine

... drug effects on behavior change. Dopamine agonists were examined under conditions that produced low and high levels of variability. In Experiment 1, D-amphetamine and dopamine-receptor-specific agonists (quinpirole and SKF 38393) were examined with rats that lever-pressed under a Multiple VARY 8:4 Fi ...
Delay aversion - Utrecht University Repository
Delay aversion - Utrecht University Repository

... Per experiment, two analyses were made. The first is a repeated measures ANOVA of the preference for the large reward per block, with the delay to the large reward and the dosage as within-subjects variables. Post-hoc tests of the different dosages were corrected for comparisons with vehicle only. Pos ...
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No Slide Title

... Insomnia Asthenia Nausea ...
cocaine-induced behavioral sensitization and
cocaine-induced behavioral sensitization and

... elevate mood, suppress appetite, aid in digestion, and was used to treat a variety of illnesses including fatigue, sinus infections, headaches, and to sustain performance. Today, cocaine is classified as a Schedule II drug which indicates that it has a high potential for abuse, but also maintains li ...
IN VIVO SATIVA Research Article
IN VIVO SATIVA Research Article

... are hormone-like molecules normally found in the body, where they have a wide variety of effects, some of which lead to pain, fever, and inflammation. In the study, injection of commonly used NSAIDs (indomethacin) was observed to significantly reduce inflammatory indices while histamine and 5- hydeo ...
Understanding and Managing Drug Interactions in HIV Disease
Understanding and Managing Drug Interactions in HIV Disease

... benefit. This is especially problematic, given that cross-class resistance among PIs is common. In general, patients failing therapy with one PI often do not experience sustained benefit from switching to another PI; (NB: an exception to this is with nelfinavir, where the presence of an isolated D30 ...
Saffron (Crocus sativus L.) and morphine
Saffron (Crocus sativus L.) and morphine

... (Hosseinzadeh H. 2010). Thus, the interaction of this constituent with the opioid system should be more specific. Administration of safranal potentiated some signs of withdrawal syndrome. Then, it seems that the aqueous and ethanolic extracts and crocin may have interaction with the opioid system to ...
Synephrine, Octopamine and Caffeine Health Risk
Synephrine, Octopamine and Caffeine Health Risk

... At doses up to 50 mg/day in healthy adults, p-synephrine is classified as Type III, except in cases where the necessary cautionary statements (i.e. contraindicated in children, pregnancy, and breast-feeding, do not use if you are taking blood pressure medications (either hypertensives or antihyperte ...
Update on Marijuana and Cannabinoid
Update on Marijuana and Cannabinoid

... -  Involved in regulation of sleep, memory, inflammation, immune functions, insulin sensitivity, fat and energy metabolism, reproduction (ovulation, implantation), expressed in breastmilk -  THC and some other cannabinoids augment the action of endocannbinoids -  Anandamide is degraded by FAAH (fatt ...
Developing an Animal Model of Polysubstance Abuse in Adolescence
Developing an Animal Model of Polysubstance Abuse in Adolescence

... Repeated exposure to drugs of abuse conditions individuals to anticipate the behavioral consequences of drug use specifically in the presence of a drug-associated context. In rodents, preferences and aversions for alcohol and cocaine have been conditioned; however, the mechanisms underlying the expr ...
Chloral hydrate has general CNS depressant effects believed to be
Chloral hydrate has general CNS depressant effects believed to be

... Warnings: Abuse and Dependence: Chloral hydrate should be used as a hypnotic only for short-term use, usually 2 to 7 days. Prolonged use of chloral hydrate may produce tolerance and physical and/or psychological dependence. Sudden withdrawal after prolonged use may result in hallucinations and symp ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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