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The Antidepressants - Consumer Health Choices
The Antidepressants - Consumer Health Choices

... psychotherapy or other counseling first, especially if your symptoms can be linked to a definable stressor (such as problems with your marriage, an unhappy work situation, or the illness of someone you care about). If that doesn’t help, consider an antidepressant. Some studies have found—and many ex ...
GHB Do You Know... What is it?
GHB Do You Know... What is it?

... other drugs, the effects are more intense, and the risk of toxic effects and overdose increases. GHB-related deaths usually involve other drugs, such as alcohol. GHB is a potent sedative, causing users to lose consciousness and fall into a deep sleep from which they might not wake for several hours. ...
Reconsidering GHB: orphan drug or new model antidepressant?
Reconsidering GHB: orphan drug or new model antidepressant?

... Abstract: For six decades, the principal mode of action of antidepressant drugs is the inhibition of monoamine re-uptake from the synaptic cleft. Tricyclic antidepressants, selective serotonin re-uptake inhibitors (SSRIs) and the new generation of dual antidepressants all exert their antidepressant ...
A study with cumulative doses of formoterol and salbutamol in
A study with cumulative doses of formoterol and salbutamol in

... drug. The difference in effect between the dose levels (0-1, 1- 2, 2-3, 3 to final administration of 1 mg salbutamol) of each drug was tested by Wilcoxon's signed rank test. For comparison between the two treatments at each dose level, absolute values were applied to pulse rate, blood pressure and t ...
OVERVIEW OF CHIRALITY AND CHIRAL DRUGS
OVERVIEW OF CHIRALITY AND CHIRAL DRUGS

... acid and is found in the cell sap of plants in two isomeric forms, levo- and dextro-asparagin. The l -form exists in asparagus, beet-root, wheat, and many seeds and is tasteless, while the d -form is sweet. Thalidomide is another classical example. It was first synthesized as a racemate in 1953 and ...
Vioxx
Vioxx

... Merck’s decision to withdraw Vioxx from the market is based on new data from a trial called the APPROVe [ Adenomatous Polyp Prevention on VIOXX] trial. In the APPROVe trial, Vioxx was compared to placebo (sugar-pill). The purpose of the trial was to see if Vioxx 25 mg was effective in preventing the ...
Fosaprepitant/Hyoscine    1733
Fosaprepitant/Hyoscine 1733

... CNS in a similar manner to atropine. However, hyoscine does not stimulate the medullary centres and therefore does not produce the increases in respiration rate or blood pressure seen with atropine. Hyoscine may produce CNS stimulation rather than depression at therapeutic doses if used in the prese ...
- University of Mississippi
- University of Mississippi

... become limp and unexpectedly drop to the ground. These seizures are also referred to as drop attacks and often result in injury (“Types of Seizures”, 2016). Unlike generalized seizures, in focal/partial seizures consciousness is not lost and the region of the brain affected is limited to a particul ...
Evaluation of Dependence and Withdrawal in Clinical Trials
Evaluation of Dependence and Withdrawal in Clinical Trials

... amount of it to achieve a certain effect (tolerance) and eliciting drugspecific physical or mental symptoms if drug use is abruptly ceased (withdrawal). - It is associated with the repeated use of both known drugs of abuse and drugs with no abuse potential. (For example, the “propranolol withdrawal ...
pharmacology_2
pharmacology_2

... B. Connect with Н2-histamine receptors C. Stimulate secretion of salivary glands D. Does not penetrate through BBB (blood brain barrier) E. Possesses expressed sedative action ANSWER: D 57.Indicate a distinctive property of Dimedrole and Diprasine A. Stimulate histamine Н1-receptors B. Increase secr ...
Hyperforin - International Journal of Pharmacy and Pharmaceutical
Hyperforin - International Journal of Pharmacy and Pharmaceutical

... St. John’s wort (SJW) extracts, prepared from the aerial parts of Hypericum perforatum, contain numerous pharmacologically active ingredients, including aphthodianthrones (e.g., hypericin and its derivatives) and phloroglucinols derivatives (e.g., hyperforin)[5]. Hyperforin is a structurally novel a ...
Herb -Drug Interactions –An Update on Synergistic Interactions
Herb -Drug Interactions –An Update on Synergistic Interactions

... combined with synthetic antifungal agents mancozeb and carboxin against Fusasium verticilloides [61]. The synergistic effect was also observed between scopoletin and other isolated constituents from the same plant viz vanillin, 4-hydroxy-3-methoxycinnamaldehyde and pinoresinol. Recently, synergistic ...
Diuretics for hypertension: Hydrochlorothiazide or chlorthalidone?
Diuretics for hypertension: Hydrochlorothiazide or chlorthalidone?

... action than hydrochlorothiazide. This may be because it has a very high volume of distribution, since it is taken up into red blood cells and is bound to carbonic anhydrase.12 This may result in a “drug reservoir” that keeps drug levels higher for a longer time.13 Its long duration of action makes i ...
Drugs Acting on the Respiratory System
Drugs Acting on the Respiratory System

... epithelial cells. In susceptible individuals, this inflammation causes recurrent episodes of wheezing, breathlessness, chest tightness, and coughing, particularly at night or in the early morning. These episodes are usually associated with widespread but variable airflow obstruction that is often re ...
Fentanyl - CannAmm
Fentanyl - CannAmm

... required by the Food and Drug Administration called a Risk Evaluation and Mitigation Strategy (REMS). As of 2012, fentanyl was the most widely used synthetic opioid in medicine. In 2013, 1700 kilograms were used globally. Fentanyl is broadly applied in medicine; it is a very safe surgical anesthetic ...
Multiple mechanisms involved in the large-spectrum
Multiple mechanisms involved in the large-spectrum

... Cannabidiol (CBD) is a major phytocannabinoid present in the Cannabis sativa plant. It lacks the psychotomimetic and other psychotropic effects that the main plant compound D9-tetrahydrocannabinol (THC) being able, on the contrary, to antagonize these effects. This property, together with its safety ...
Commonly Prescribed Psychiatric Medications
Commonly Prescribed Psychiatric Medications

... Initial dose: 0.5 to 5 mg orally 2 to 3 times a day. A "typical" antipsychotic, one of the oldest, usually given in conjunction with "cogentin", an antiparkinsonic. This is due Dosage may go up to: 1 to 30 mg/day in 2 or 3 to the high occurrence of tardive dyskinesia on patients with prolonged Haldo ...
030106b - Veterinaria.org
030106b - Veterinaria.org

... Hawkey et al. (1998) compared omeprazole with misoprostol for ulcers and erosions associated with nonsteroidal antiinflammatory drugs. They found that the overall rates of successful treatment of ulcers, erosions, and symptoms associated with NSAIDs were similar for the two doses of omeprazole and m ...
4427 Naltrexone/Carers.NSW
4427 Naltrexone/Carers.NSW

... As a carer, let the person know that you will support and care for them and that they will not be undergoing the naltrexone treatment alone. Establish the fact that you may be supervising their dosage. Explain to them that it is not because you don't trust them but because you are their carer and su ...
NIOSH List of Hazardous Drugs - University of Kansas Medical Center
NIOSH List of Hazardous Drugs - University of Kansas Medical Center

... Institutions may want to adopt this list or compare theirs with the list on the NIOSH Web site. Caution: Drugs purchased and used by a facility may have entered the marketplace after the list below was assembled. Therefore, this list may not be all-inclusive. If you use a drug that is not included i ...
0316065.01 - Society of Nuclear Medicine
0316065.01 - Society of Nuclear Medicine

... CMS identifies that Zevalin consists of a radioactive isotope that is delivered to its target tissue by a monoclonal antibody. “Because of the specific requirements associated with delivery of radioactive isotope therapy, any product containing a therapeutic radioisotope will be considered under the ...
DESIGNER & CLUB DRUGS IN OUR COMMUNITY  Patricia Junquera, MD
DESIGNER & CLUB DRUGS IN OUR COMMUNITY Patricia Junquera, MD

... Junquera & Castellanos, 2014 ...
EVALUATION OF ANALGESIC, ANTI-INFLAMMATORY AND ANTIPYRETIC POTENTIAL OF SWERTIA CORYMBOSA Research Article
EVALUATION OF ANALGESIC, ANTI-INFLAMMATORY AND ANTIPYRETIC POTENTIAL OF SWERTIA CORYMBOSA Research Article

... higher over the positive drug pentazocine. At the dose level 200 mg/kg and 240 min reaction time, the analgesic activity(8.90 ± 0.40 s) of the test extract was higher than that of the standard drug pentazocine (8.10 ± 0.90s). Thermic painful stimuli are known to be selective to centrally active drug ...
NSAIDS compared - Consumer Reports Health
NSAIDS compared - Consumer Reports Health

... questions, such as: At what dose and over what period of time do NSAIDs become unsafe and the dangers outweigh the benefits? And given that the various NSAIDs have differing effects on the COX-2 enzyme, what does that mean regarding their relative safety? The available evidence indicates that other ...
Advice to The Expert Advisory Committee on drugs on: LSD
Advice to The Expert Advisory Committee on drugs on: LSD

... 6. LSD is a semi-synthetic hallucinogen and belongs to a class of indolealkylamines which are structurally similar to the neurotransmitter serotonin and act through the serotonin system1. This class of hallucinogens also includes psilocybin, psilocin, bufotenine and dimethyltryptamine (DMT). CURRENT ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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