Neurotransmitters - UCSD Cognitive Science
... • IV and smoked lead to fast onset and “rush” • 3 times as potent as morphine • Not directly an efficacious mu agonist, but more lipid soluble than morphine • Enters brain quickly, converted into morphine for action ...
... • IV and smoked lead to fast onset and “rush” • 3 times as potent as morphine • Not directly an efficacious mu agonist, but more lipid soluble than morphine • Enters brain quickly, converted into morphine for action ...
1 DRUGS IN ADVANCED CARDIAC LIFE SUPPORT
... Evidence no longer supports the use of lignocaine as a diagnostic discriminator between perfusing VT and widecomplex tachycardia of uncertain origin Lignocaine is NOT recommended for ventricular escape ...
... Evidence no longer supports the use of lignocaine as a diagnostic discriminator between perfusing VT and widecomplex tachycardia of uncertain origin Lignocaine is NOT recommended for ventricular escape ...
Slide 1 - Gordon State College
... Copyright © 2012 by Pearson Education, Inc. All rights reserved. ...
... Copyright © 2012 by Pearson Education, Inc. All rights reserved. ...
Document
... Inhalation: (MDI, Nebulizer); Is the best. Why? Oral: children < 5 years-prophylaxis Parenteral: rarely used e.g. in SA Compare between oral and inhalation B2 agonists? Dosesystemic effect-distribution in lung-Compliance-ease of ...
... Inhalation: (MDI, Nebulizer); Is the best. Why? Oral: children < 5 years-prophylaxis Parenteral: rarely used e.g. in SA Compare between oral and inhalation B2 agonists? Dosesystemic effect-distribution in lung-Compliance-ease of ...
Glucocorticosteroids
... All regions of the adrenal cortex are destroyed in Addison’s disease. We will give steroids that will mimic the circadian rhythm. We give 2/3 dose in the morning and 1/3 in the evening. Adverse Effects Steroids can have adverse effects on carbohydrates, lipid, and proteins. They are involved with gl ...
... All regions of the adrenal cortex are destroyed in Addison’s disease. We will give steroids that will mimic the circadian rhythm. We give 2/3 dose in the morning and 1/3 in the evening. Adverse Effects Steroids can have adverse effects on carbohydrates, lipid, and proteins. They are involved with gl ...
Caffeine, Acting on Adenosine A1 Receptors, Prevents the
... This paper is available online at http://www.jpet.org ...
... This paper is available online at http://www.jpet.org ...
Chapter_1:introduction to medicinal chemistry
... The activity of a drug is its pharmacological effect on the subject (e.g. analgesic or β-blocker) The potency of a drug is the quantitative measure of the activity. The duration of action of a drug is the period of time during which the activity is exerted at certain potency range. Other terms ...
... The activity of a drug is its pharmacological effect on the subject (e.g. analgesic or β-blocker) The potency of a drug is the quantitative measure of the activity. The duration of action of a drug is the period of time during which the activity is exerted at certain potency range. Other terms ...
1. b-adrenergic Blockers
... 4) Drugs that block production or action of angiotensin I Why it is so fortunate that these drugs have different mechanisms and site of action? ...
... 4) Drugs that block production or action of angiotensin I Why it is so fortunate that these drugs have different mechanisms and site of action? ...
The Complexity of Herb-Drug Interaction Research
... Example 3: Herb-Drug Interaction? – Some but not all Trials controlled for the dosage† Midazolam, alprazolam and nifedipine are metabolised mainly by CYP3A4. Ginkgo decreased drug levels of and exposure to midazolam.7 Ginkgo had no clinically-relevant effect on exposure to alprazolam.8 Ginkgo had no ...
... Example 3: Herb-Drug Interaction? – Some but not all Trials controlled for the dosage† Midazolam, alprazolam and nifedipine are metabolised mainly by CYP3A4. Ginkgo decreased drug levels of and exposure to midazolam.7 Ginkgo had no clinically-relevant effect on exposure to alprazolam.8 Ginkgo had no ...
Complete Drug Facts
... to talk a lot, and pupils may become dilated. Other less popular effects are anxiety, paranoia, irritability. Amphetamines elevate levels of dopamine and adrenalin. This causes intense euphoria and feelings of well being, but also puts significant strain on the cardiovascular system. Methamphetamine ...
... to talk a lot, and pupils may become dilated. Other less popular effects are anxiety, paranoia, irritability. Amphetamines elevate levels of dopamine and adrenalin. This causes intense euphoria and feelings of well being, but also puts significant strain on the cardiovascular system. Methamphetamine ...
Abnormal laboratory results Therapeutic drug monitoring: which
... patients having frequent seizures) – diagnosing undertreatment (particularly important for prophylactic drugs such as anticonvulsants, immunosuppressants) – diagnosing failed therapy (therapeutic drug monitoring can help distinguish between ineffective drug treatment, non-compliance and adverse ef ...
... patients having frequent seizures) – diagnosing undertreatment (particularly important for prophylactic drugs such as anticonvulsants, immunosuppressants) – diagnosing failed therapy (therapeutic drug monitoring can help distinguish between ineffective drug treatment, non-compliance and adverse ef ...
Tobacco Research at NIDA: Basic Science, Prevention
... • National, longitudinal cohort study of ~46,000 users of tobacco products and those at risk for tobacco use ages 12 and older in the U.S. • Funded by the Center for Tobacco Products, FDA. • Results from this study will help inform the impact of FDA regulatory authority over tobacco products, and he ...
... • National, longitudinal cohort study of ~46,000 users of tobacco products and those at risk for tobacco use ages 12 and older in the U.S. • Funded by the Center for Tobacco Products, FDA. • Results from this study will help inform the impact of FDA regulatory authority over tobacco products, and he ...
Gastrointestinal Disorders and Medication Management Drugs for
... o Give before food (preferably breakfast) Cautious use o Hepatic and renal insufficiency ...
... o Give before food (preferably breakfast) Cautious use o Hepatic and renal insufficiency ...
Drugs for Dementia
... more important. Carers' views on the patient's condition at follow-up should be sought When should the drug be stopped? Drugs should be stopped if a patient developed an allergy or contra-indication to the medication. If a patient is not apparently gaining any benefit from the drug that may be an in ...
... more important. Carers' views on the patient's condition at follow-up should be sought When should the drug be stopped? Drugs should be stopped if a patient developed an allergy or contra-indication to the medication. If a patient is not apparently gaining any benefit from the drug that may be an in ...
A new trend in drugs-of-abuse
... 2C-T-2 and 2C-T-7 indicated minimal physical symptoms when administered orally in the range of approximately 10 to 30 mg 7, 12. A review on structure-activity relationships suggested that in this dose range the relative potency of the mentioned drugs was 15–16 times that of mescaline 13. However, th ...
... 2C-T-2 and 2C-T-7 indicated minimal physical symptoms when administered orally in the range of approximately 10 to 30 mg 7, 12. A review on structure-activity relationships suggested that in this dose range the relative potency of the mentioned drugs was 15–16 times that of mescaline 13. However, th ...
The Pharmacological Constituents of Mescaline
... from the LC projects to layer V pyramidal cells in the neocortex (as do 5HT inputs from raphe nuclei) Noradrenaline acting via alpha –1 receptors also induces an increase in glutamate release ...
... from the LC projects to layer V pyramidal cells in the neocortex (as do 5HT inputs from raphe nuclei) Noradrenaline acting via alpha –1 receptors also induces an increase in glutamate release ...
Pharmacokinetics
... of administration of drug to the site of action as well as its elimination. b. (Drawing on board): concentration on y and time on X axis. Lets say you take 2 pills of Motrin and over time you want to see the level of that drug in the blood. So over time it reaches its peak level and slowly its conce ...
... of administration of drug to the site of action as well as its elimination. b. (Drawing on board): concentration on y and time on X axis. Lets say you take 2 pills of Motrin and over time you want to see the level of that drug in the blood. So over time it reaches its peak level and slowly its conce ...
PSY650-Antipsychotics-Sedative-Hypnotics
... – Serotonin-related symptoms (10-40% patients): constipation, drowsiness, headache, hypersaliation, hypotension, tachycardia – Neutropenia (2% patients) decrease in neutrophil count in blood. Increases susceptibility to bacterial and fungal infections • Fatal! ...
... – Serotonin-related symptoms (10-40% patients): constipation, drowsiness, headache, hypersaliation, hypotension, tachycardia – Neutropenia (2% patients) decrease in neutrophil count in blood. Increases susceptibility to bacterial and fungal infections • Fatal! ...
THE EXTENT OF POPULATION EXPOSURE TO ASSESS CLINICAL
... Long-term studies to show efficacy (and which are also needed for assessment of long term safety) would usually use active controls, preferably with a placebo-controlled randomized withdrawal study at the end of treatment to establish assay sensitivity (See ICH E10) and assess possible withdrawal ef ...
... Long-term studies to show efficacy (and which are also needed for assessment of long term safety) would usually use active controls, preferably with a placebo-controlled randomized withdrawal study at the end of treatment to establish assay sensitivity (See ICH E10) and assess possible withdrawal ef ...
The Challenges of Methamphetamine
... – CANNOT be used by physician for maintenance (outside of a licensed program) – May use for MAX of 3 days while patient waits to get into a program – OK to use for pain control – OK to use in acute hospital setting for detoxification for ‘non opioid addiction’ admission (infection, etc) ...
... – CANNOT be used by physician for maintenance (outside of a licensed program) – May use for MAX of 3 days while patient waits to get into a program – OK to use for pain control – OK to use in acute hospital setting for detoxification for ‘non opioid addiction’ admission (infection, etc) ...
Substance Abuse
... – CANNOT be used by physician for maintenance (outside of a licensed program) – May use for MAX of 3 days while patient waits to get into a program – OK to use for pain control – OK to use in acute hospital setting for detoxification for ‘non opioid addiction’ admission (infection, etc) ...
... – CANNOT be used by physician for maintenance (outside of a licensed program) – May use for MAX of 3 days while patient waits to get into a program – OK to use for pain control – OK to use in acute hospital setting for detoxification for ‘non opioid addiction’ admission (infection, etc) ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.