Bioisosteres
... means less toxicity To decrease side effects and toxicity To increase or decrease metabolism balance (biodegradable + stable) biodegradable so that we get an effect, but stable and resistant to metabolism at the same time so that it reaches the target #BALANCE Ease of administration (oral instea ...
... means less toxicity To decrease side effects and toxicity To increase or decrease metabolism balance (biodegradable + stable) biodegradable so that we get an effect, but stable and resistant to metabolism at the same time so that it reaches the target #BALANCE Ease of administration (oral instea ...
Basic pharmacology
... # Curative, as primary therapy (bacterial / parasitic infections), or auxilary therapy (anaesthetics, ergometrine and oxytocin in obstetrics) # Suppressive of disease/symptoms, used continuely or intermittently to maintain health with out attaining cure as in hypertension, diabetes, epilepsy, astham ...
... # Curative, as primary therapy (bacterial / parasitic infections), or auxilary therapy (anaesthetics, ergometrine and oxytocin in obstetrics) # Suppressive of disease/symptoms, used continuely or intermittently to maintain health with out attaining cure as in hypertension, diabetes, epilepsy, astham ...
Antiemetic drugs
... or prokinetic, is a type of drug which enhances gastrointestinal motility by increasing the frequency of contractions in the small intestine or making them stronger, but without disrupting their rhythm. • They are used to treat irritable bowel syndrome, gastritis, acid reflux disease, gastroparesis, ...
... or prokinetic, is a type of drug which enhances gastrointestinal motility by increasing the frequency of contractions in the small intestine or making them stronger, but without disrupting their rhythm. • They are used to treat irritable bowel syndrome, gastritis, acid reflux disease, gastroparesis, ...
Drug Free Workplace Statement - South Carolina State University
... a variety of aggressive acts. Moderate to high doses of alcohol cause marked impairment in higher mental functions, severely altering a person’s ability to learn and remember information. Heavy use may result in chronic depression and suicide and also may be associated with the abuse of other drugs. ...
... a variety of aggressive acts. Moderate to high doses of alcohol cause marked impairment in higher mental functions, severely altering a person’s ability to learn and remember information. Heavy use may result in chronic depression and suicide and also may be associated with the abuse of other drugs. ...
Parkinson`s disease
... – Best results obtained in first few years of treatment. – 80% of patients show marked initial improvement (primarily in terms of resolution of muscle rigidity and bradykinesia). – 20% show virtually normal motor function. – Over time, levodopa therapy becomes less effective • Progressive loss o ...
... – Best results obtained in first few years of treatment. – 80% of patients show marked initial improvement (primarily in terms of resolution of muscle rigidity and bradykinesia). – 20% show virtually normal motor function. – Over time, levodopa therapy becomes less effective • Progressive loss o ...
Cocaine - Youville
... Is cocaine addictive? It can be. Not everyone who uses cocaine becomes addicted, but if they do, it can be one of the hardest drug habits to break. People who become addicted to cocaine lose control over their use of the drug. They feel a strong need for cocaine, even when they know it causes them m ...
... Is cocaine addictive? It can be. Not everyone who uses cocaine becomes addicted, but if they do, it can be one of the hardest drug habits to break. People who become addicted to cocaine lose control over their use of the drug. They feel a strong need for cocaine, even when they know it causes them m ...
Mood_disorders_III_m..
... • In older adults who can't tolerate drug side effects • In people who prefer ECT treatments over taking medications • When ECT has been successful in the past ...
... • In older adults who can't tolerate drug side effects • In people who prefer ECT treatments over taking medications • When ECT has been successful in the past ...
Monte Casino Shows November
... The gentle art of inhaling burnt tobacco leaf has some unfortunate side effects. The associated risks of lung cancer, heart and vascular disease are well known. There are more subtle effects. A smoker inhales carbon monoxide, which binds to the haemoglobin and reduces the blood's ability to transpor ...
... The gentle art of inhaling burnt tobacco leaf has some unfortunate side effects. The associated risks of lung cancer, heart and vascular disease are well known. There are more subtle effects. A smoker inhales carbon monoxide, which binds to the haemoglobin and reduces the blood's ability to transpor ...
20808 AlleRx PE.indd
... on monoamine oxidase inhibitor (MAOI) therapy or within 14 days of stopping monoamine oxidase inhibitor (MAOI) therapy, and in nursing mothers. AlleRx PE is also contraindicated in patients with narrow-angle glaucoma, urinary retention, peptic ulcer, and during an asthmatic attack. WARNINGS Sympatho ...
... on monoamine oxidase inhibitor (MAOI) therapy or within 14 days of stopping monoamine oxidase inhibitor (MAOI) therapy, and in nursing mothers. AlleRx PE is also contraindicated in patients with narrow-angle glaucoma, urinary retention, peptic ulcer, and during an asthmatic attack. WARNINGS Sympatho ...
Commentary on: Psilocybin can occasion mystical
... virtually impossible for psychoactive agents. Surprisingly, even the sophisticated monitors mistook one of the drugs for the other in about 25% of the sessions. Thus, the study results are not likely to be contaminated by expectant attitudes and biases of experimenters and/or subjects. Psilocybin el ...
... virtually impossible for psychoactive agents. Surprisingly, even the sophisticated monitors mistook one of the drugs for the other in about 25% of the sessions. Thus, the study results are not likely to be contaminated by expectant attitudes and biases of experimenters and/or subjects. Psilocybin el ...
No Slide Title
... Non-adherence due to methamphetamine use • 100% of participants claimed that their substance use had an effect on their HIV medication adherence ...
... Non-adherence due to methamphetamine use • 100% of participants claimed that their substance use had an effect on their HIV medication adherence ...
A summary of the health harms of drugs
... A potentially life threatening drug reaction that causes the body to have too much serotonin ...
... A potentially life threatening drug reaction that causes the body to have too much serotonin ...
Antimicrobial Fundamental Concepts
... one organism, that does not mean that it, or all the other drugs in its class, are concentration dependent and bactericidal against all organisms. However, because of a lack of data characterizing the pharmacodynamic properties of various antimicrobials against several different organisms, we usuall ...
... one organism, that does not mean that it, or all the other drugs in its class, are concentration dependent and bactericidal against all organisms. However, because of a lack of data characterizing the pharmacodynamic properties of various antimicrobials against several different organisms, we usuall ...
L8-drugs affecting breast milk and lactation
... if she is suffered from different diseases as epilepsy, infection, diabetes, heart failure, hypertension. ...
... if she is suffered from different diseases as epilepsy, infection, diabetes, heart failure, hypertension. ...
Study Objectives
... 8. How does nicotine withdrawal differ from withdrawal from other substances? What treatments reduce nicotine withdrawal symptoms? 9. Summarize laboratory research evidence regarding reinforcing properties of nicotine. 10. Identify and discuss the three primary causes of death associated with cigare ...
... 8. How does nicotine withdrawal differ from withdrawal from other substances? What treatments reduce nicotine withdrawal symptoms? 9. Summarize laboratory research evidence regarding reinforcing properties of nicotine. 10. Identify and discuss the three primary causes of death associated with cigare ...
GENERIC NAME: venlafaxine
... Nardil and Parnate. MAO inhibitors and venlafaxine should not be taken together, and a waiting period of 14 days between taking these two classes of medications is strongly advised. Most medications affecting the brain such as venlafaxine have the potential to slow reflexes or impair judgment. There ...
... Nardil and Parnate. MAO inhibitors and venlafaxine should not be taken together, and a waiting period of 14 days between taking these two classes of medications is strongly advised. Most medications affecting the brain such as venlafaxine have the potential to slow reflexes or impair judgment. There ...
Smoking Cessation and Chronic Mental Illness
... Chronic Disease Long-Term Disorder Periods of relapse and remission Requires ongoing rather than acute care Examples: ...
... Chronic Disease Long-Term Disorder Periods of relapse and remission Requires ongoing rather than acute care Examples: ...
Getting High on Prescription and Over-the
... distinguish among the types and effects of drugs some teens use to get high. Some of these drugs are described below. ...
... distinguish among the types and effects of drugs some teens use to get high. Some of these drugs are described below. ...
Phases of Drug Action
... Factors Affecting Distribution Plasma Protein Binding - drugs bind to proteins in the blood (albumin, globulins) in varying degrees, from highly bound to poorly bound Protein binding decreases the concentration of free drug in circulation therefore there is a limited amount of drug available to tra ...
... Factors Affecting Distribution Plasma Protein Binding - drugs bind to proteins in the blood (albumin, globulins) in varying degrees, from highly bound to poorly bound Protein binding decreases the concentration of free drug in circulation therefore there is a limited amount of drug available to tra ...
Dopamine Receptor Antagonists Reverse Amphetamine
... behavior maintained on a schedule of differential reinforcement of low-rate (DRL). As such, behavioral deficiency of DRL responding has been observed by the drug-induced increase of non-reinforced responses and a leftward shift of inter-response time (IRT) curve on DRL responding in the rat. However ...
... behavior maintained on a schedule of differential reinforcement of low-rate (DRL). As such, behavioral deficiency of DRL responding has been observed by the drug-induced increase of non-reinforced responses and a leftward shift of inter-response time (IRT) curve on DRL responding in the rat. However ...
B.Pharm Revised 2003-04 Final Year With Elective Subject
... 2. Regulatory control, regulatory drug analysis and interpretation of analytical data. 3. Validation quality of equipment, validation of equipment and validation of analytical ...
... 2. Regulatory control, regulatory drug analysis and interpretation of analytical data. 3. Validation quality of equipment, validation of equipment and validation of analytical ...
GENERAL PRINCIPLES OF PHARMACOLOGY
... effect, two drugs with the same effect are given together — similar to 1+1=2. Synergism—two drugs with the same effect are given together and produce a response greater than the sum of their individual responses — similar to 1+2=3. ...
... effect, two drugs with the same effect are given together — similar to 1+1=2. Synergism—two drugs with the same effect are given together and produce a response greater than the sum of their individual responses — similar to 1+2=3. ...
DRUG INTERACTIONS AND ANESTHESIA
... ♦ Nitroglycerin (NTG) adsorbs to, absorbs into, and penetrates the wall of plastic container or infusion set. Polyethylene reduces NTG concentration by 15%, PVC up to 70%. It remains possible that changes in hemodynamic status could occur in patients on NTG if a change in container type (i.e., from ...
... ♦ Nitroglycerin (NTG) adsorbs to, absorbs into, and penetrates the wall of plastic container or infusion set. Polyethylene reduces NTG concentration by 15%, PVC up to 70%. It remains possible that changes in hemodynamic status could occur in patients on NTG if a change in container type (i.e., from ...
Determinants of Neonatal Cardiac Output
... – No differences found rate treatment failure – Conclusion: “Low/mod-dose E is as effective as low/mod dose D for treatment hypotension in low birth weight infants, although is associated with more transitory adverse effects” ...
... – No differences found rate treatment failure – Conclusion: “Low/mod-dose E is as effective as low/mod dose D for treatment hypotension in low birth weight infants, although is associated with more transitory adverse effects” ...
ARA Prescriber`s Information on Medications for Rheumatic
... Up to 20% of women with RA have worsening of joint symptoms with pregnancy compared with control populations. RA patients have an increased risk of pre-eclampsia (PET), Caesarean section, and premature or low birth weight (LBW) neonates. In PsA disease activity does not typically change during pregn ...
... Up to 20% of women with RA have worsening of joint symptoms with pregnancy compared with control populations. RA patients have an increased risk of pre-eclampsia (PET), Caesarean section, and premature or low birth weight (LBW) neonates. In PsA disease activity does not typically change during pregn ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.