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Substance Abuse
Substance Abuse

... – CANNOT be used by physician for maintenance (outside of a licensed program) – May use for MAX of 3 days while patient waits to get into a program – OK to use for pain control – OK to use in acute hospital setting for detoxification for ‘non opioid addiction’ admission (infection, etc) ...
click here
click here

... • Methodological difficulties  between studies make comparison  complicated • The era in which the drug was approved  • Phenobarbital vs carbamazepine vs vigabatrin ...
Antifungal Agents
Antifungal Agents

... Azole group of antifungal agents Broad spectrum of fungal pathogens Uses ...
2011 GEM Drugs Elderly
2011 GEM Drugs Elderly

... What are the Drug Therapy Problems (DTP) What do we hope to achieve What is the best therapeutic plan What is the monitoring plan ...
Cannabis—A Valuable Drug That Deserves Better Treatment
Cannabis—A Valuable Drug That Deserves Better Treatment

... critically and very well presented both aspects. In most countries, including the United States, marijuana is a Schedule I controlled substance (high potential for abuse; no currently accepted medical use). Like individuals, countries can also be hypocritical. In contrast to marijuana, THC, also cal ...
Profile: Oxycodone - CESAR
Profile: Oxycodone - CESAR

... pharmacists have also prescribed and sold controlled substances for illicit use. ...
Department of Pharmacology
Department of Pharmacology

... general mechanisms of drug of drug metabolism. General mechanisms of drug interaction interactions (classification of drug interactions, mechanisms of drug interactions, factors influencing drug interactions, drug interaction used in pharmacotherapeutics) Autonomic adrenergic For repetition: functio ...
1 Peyote Cactus San Pedro Cactus San Pedro Varieties
1 Peyote Cactus San Pedro Cactus San Pedro Varieties

... Noradrenaline acting via alpha –1 receptors also induces an increase in glutamate release ...
Cholinergics and Anticholinergics
Cholinergics and Anticholinergics

... • Poorly absorbed orally so requires larger doses  than when given parenterally. • Can develop resistance to its action over time ...
Assessment of the Influence of Histaminergic Actions on Cocaine
Assessment of the Influence of Histaminergic Actions on Cocaine

... Downloaded from jpet.aspetjournals.org at ASPET Journals on August 12, 2017 ...
1 spasmolytics
1 spasmolytics

... • Baclofen (p-chlorophenyl-GABA) was designed to be an orally active GABA-mimetic agent, its spasmolytic activity at GABAB receptors, this result in: – hyperpolarization, probably by increased K+ conductance. – inhibition of reducing calcium influx – This will reduce excitation of spinal cords and r ...
Lecture 8
Lecture 8

... more people compared to phase II; generates more info on dosing and safety ...
Bodybuilding Supplement Update
Bodybuilding Supplement Update

... there’s a recent study showing that a single dose of ephedra-guarana supplement can produce significant increases in blood pressure and resting heart rate in healthy young adults. However, I believe this is a fake report. You see, the first and third authors of this paper have served as “expert witn ...
Basic concepts in clinical pharmacology
Basic concepts in clinical pharmacology

... (oral sumatriptan; normal volunteer) Cmax (= 50 ng/mL) ...
docx - Health Vista
docx - Health Vista

... o Chlorzoxazone (Paraflex, Parafon Forte, Remular-S) o Cyclobenzaprine (Flexeril) o Medaxalone (Skelaxin) o Methocarbamol (Robaxin) o Orphenadrine (Norflex) o Tizanidine (Zanaflex) 2. Mechanism of Action for Centrally Acting Muscle Relaxants o Mechanism uncertain, but probably from sedative properti ...
A Matching Law Analysis of the Effect of Amphetamine
A Matching Law Analysis of the Effect of Amphetamine

... Tsuda, 1981; Jakubczak & Gomer, 1973; Tainter, 1943) whereas dopamine antagonists such as pimozide and chlorpromazine decrease running (Beninger & Freedman, 1982; Routtenberg, 1968; Routtenberg & Kuznesof, 1967). However, this evidence must be viewed with a degree of skepticism because it fails to d ...
Mood disorders III Case Management Discussion including ECT
Mood disorders III Case Management Discussion including ECT

... • In older adults who can't tolerate drug side effects • In people who prefer ECT treatments over taking medications • When ECT has been successful in the past ...
2nd T. 5th L. Updated
2nd T. 5th L. Updated

... Acetic Acid Derivatives, Sulindac  Sulindac is a prodrug whose anti-inflammatory activity resides in its sulfide metabolite. About 90% of it is absorbed after oral administration. Peak plasma concentrations of sulindac are attained within 1 to 2 hrs, while those of the sulfide metabolite occur abo ...
OPIOID ANALGESICS
OPIOID ANALGESICS

... MOA OF MORPHINE  Certain opioid receptors are located on primary afferent and spinal cord pain transmission neurons(ascending pathways) and on neurons in the midbrain and medulla(descending pathways) that ...
TO STUDY THE PRESCRIBING PATTERN OF ANTIPSYCHOTIC DRUGS IN A... HOSPITAL OF ASSAM.  Original Article
TO STUDY THE PRESCRIBING PATTERN OF ANTIPSYCHOTIC DRUGS IN A... HOSPITAL OF ASSAM. Original Article

... consequences. Drug utilization research affords a baseline reference points about the effect of diverse interventions in prescribing the concerned drugs. [1]. Antipsychotics are a class of agents which are able to reduce psychotic symptoms in a wide range of conditions like schizophrenia, bipolar di ...
moravek-arma1
moravek-arma1

... intoxication, nevertheless, addicts could accept it better for long-term therapy. • Olanzepine is found out to be very acceptable as drug for lower abstinence symptoms, depressive symptoms in dually diagnosed patients. • Carbamazepine could be helpful in bensodiasepine abstinence syndrome, and lower ...
Chapter 11 Objectives
Chapter 11 Objectives

... produce mild CNS depression known as sedation( reduction of activity and simple anxiety) and larger doses produce greater CNS depression like inducing sleep. This is referred to as the hypnotic dose. Even larger doses produce anesthesia and finally death. 2. Describe the impact that dental treatment ...
Common Drugs of Abuse
Common Drugs of Abuse

... which a baby can suffer from dependence and withdrawal symptoms after birth. Pregnancy-related issues are listed in the chart below for drugs where there is enough scientific evidence to connect the drug use to negative effects. However, most drugs could potentially harm an unborn baby. In the chart ...
Powerpoint
Powerpoint

... Summary of the TB Story • Entacapone and tolcapone shown to have potential for repositioning • Direct mechanism of action avoids M. tuberculosis resistance mechanisms • Possess excellent safety profiles with few side effects – already on the market • In vivo support • Assay of direct binding of ent ...
A4 Stable Angina
A4 Stable Angina

... - cardioprotective, antiHTN effects - ideal for pts with concomitant HTN,  resting HR, supraventricular tachycardia, atrial fibrillation, post-MI angina, stable CHF MOA -  HR, BP, contractility   O2 requirements and less work for the heart. - They mostly affect demand (not much of an effect on s ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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