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Current Concepts on Drug Abuse and Dependence
Current Concepts on Drug Abuse and Dependence

... consistently abstain, impairment in behavioural control, craving, diminished recognition of the significant behavioural problems and in interpersonal relationships and also dysfunctions of the emotional response (3). Like other chronic diseases, addiction often involves cycles of relapse and remissi ...
Neyroleptiklər
Neyroleptiklər

... Is a rare but serious side effect of neuroleptic (antipsychotic) therapy that can be lethal. It can arise at any time in the course of treatment and shows no predilection for age, duration of treatment, antipsychotic medication, or dose. ...
Zzzzzzz…. - The Cambridge MRCPsych Course
Zzzzzzz…. - The Cambridge MRCPsych Course

... the presence of GABA (c.f. barbiturates) • Bind specifically to regulatory site of the receptor not at the GABA-binding site • Allosteric action i.e. increase affinity of GABA for the receptor • Do not affect glycine or glutamate receptors ...
Drugs for Bronchial Asthma, Antitussives, Expectorants
Drugs for Bronchial Asthma, Antitussives, Expectorants

... bronchodilation by acting through β2 adrenergic receptors.  Useful in acute attack of asthma (0.2-0.5 ml of 1:1000 solution given s.c.  Its use decline due to serious cardiac side effects. ...
Limitations of Antiretroviral Therapy
Limitations of Antiretroviral Therapy

... • Perform test that gives mutations in viral genes  Phenotypic resistance test • Perform test that describes growth of virus in the presence of anti-HIV drugs ...
Types of Drugs
Types of Drugs

... Common components of preanesthetic protocols, mixed with a tranqulizer or an anticholingeric Used to treat and prevent post-op pain Neuroleptanalgesa is profound sedation and analgesis which can allow one to perform minor surgery (usually does not work on healthy animals) can be produced by doeses o ...
Drug Diversion Chaitali Chheda, PharmD candidate 2008 January 10, 2008
Drug Diversion Chaitali Chheda, PharmD candidate 2008 January 10, 2008

... • Ronald McIver, 63 years old, and a doctor. He is now in jail following a conviction for drug trafficking. • One patient with a severe pain condition was given high doses of OxyContin 40 mg from the start of therapy and was allowed to control her own dosing. • She didn’t bring any medical records e ...
Neurological Agents Chart
Neurological Agents Chart

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Drug Design, Testing, Manufacturing, and Marketing
Drug Design, Testing, Manufacturing, and Marketing

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SUBSTANCE ABUSE AND THE ELDERLY
SUBSTANCE ABUSE AND THE ELDERLY

... • Chronic ETOH abuse may actually increase liver enzyme induction and increase metabolism of some drugs (until the liver becomes really damaged) • Drug clearance may fluctuate because of this – especially in binge drinking. • With drugs like warfarin or anticonvulsants, this can have catastrophic co ...
Investigational New Drug (IND)
Investigational New Drug (IND)

... satisfied that the drug was safe – NOT just the manufacturer – prior to distribution ...
Section 17.1
Section 17.1

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TOPIC OUTLINE

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... • consists of 2 Ach molecules end-to-end • produces a depolarizing block – phase I - depolarizes the end-plate & adjacent muscle – phase II - with continued presence, it desensitizes the end-plate to Ach ...
Evolution of toxic properties of Anti Alzheimer`s Drugs
Evolution of toxic properties of Anti Alzheimer`s Drugs

... Optimizing the chemical structure of lead candidates with respect to the ADME processes has become an integral part of the drug discovery paradigm 3. An important ADME characteristic is simply the solubility of the drug, as only the amount of drug in solution is available for intestinal absorption a ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... Some sedative including Talen (bromazepam) can cause physiological and psychological dependence when taken regularly over a period of time, even at therapeutic doses (Ebert et al., 2006). Dependent users may get withdrawal symptoms ranging from restlessness and insomnia to convulsion and death. When ...
Blaylock Wellness Report
Blaylock Wellness Report

... problems and delayed reflexes, something you would not want to have driving or operating dangerous machinery. Researchers found that the lower the cholesterol, the worse the effects. Other studies on people taking these drugs also have reported difficulty thinking and remembering. In fact, memory lo ...
Topic D HL past paper questions 2011 (M10 – TZ2) Drugs can be
Topic D HL past paper questions 2011 (M10 – TZ2) Drugs can be

... (i) One method of injecting drugs into the body results in the drug having a very rapid effect. State the method and explain its rapid action. [2] (ii) List the two other methods which can be used to inject drugs into the body. [1] (iii) Identify the method of administration used to treat respirator ...
Aging - Pharmacology of. Geriatric Therapy
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iCup 10 Panel Drug Screening Kit Insert
iCup 10 Panel Drug Screening Kit Insert

... Amphetamine is a Schedule II controlled substance available by prescription (Dexedrine®) and is also available on the illicit market. Amphetamines are a class of potent sympathomimetic agents with therapeutic applications. They are chemically related to the human body’s natural catecholamines: epine ...
Synthetic cannabinoid case study – various brands | Male
Synthetic cannabinoid case study – various brands | Male

... collectors’ items and research chemicals. In the recent past, NPS were often sold under even more deceptive names, such as ‘plant food’ or ‘bathsalts’ but this is less common now and these products are not dual purpose. The term legal high might imply that these substances are safe but this is an in ...
Withdrawal
Withdrawal

... 1. Receptor Downregulation- Opioid receptors in the body are actively reduced due to overexposure to opioids. This can also have an effect on endogenous opioid peptide function (i.e. regular functioning of endorphins) 2. Antiopiates- Chemicals like neuropeptide FF, orphanin FQ/nociceptin, and Tyr-W- ...
INTRODUCTION TO SCIENTIFIC RESEARCH
INTRODUCTION TO SCIENTIFIC RESEARCH

... certain class of drug * There rae no drugs completely specific in action * Increase the dose will affect other targets in cell ...
Barbiturate
Barbiturate

... rhythm underlying the normal sleep–wake cycle. Ramelteon is indicated for the treatment of insomnia in which falling asleep (increased sleep latency) is the primary complaint. The potential for abuse of ramelteon is believed to be minimal, and no evidence of dependence or withdrawal effects has been ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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