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Evolutionary Genetics: Part 8 Natural Selection
Evolutionary Genetics: Part 8 Natural Selection

... Natural selection  Fitness is a trait of a phenotype  high fitness = individual produce much viable offsprings that contribute to future generations  A phenotype has a genotypic basis, so we can attribute fitness to genotypes  HOWEVER, The relationship between genotype and phenotype is complex ...
Natural Selection jeopardy edit
Natural Selection jeopardy edit

... The graph show the positive relationship between the average beak size of the finches and the average size of seeds available. Since there is a variation in finches, with different beak sizes, during the drought that caused the seeds to become bigger and harder, the natural selection occurred causin ...
Polling in Cattle - South Devon Herd Book Society
Polling in Cattle - South Devon Herd Book Society

... Similarly to polling there are two forms of the gene that control whether an animal has scurs. Again these are inherited from the parents with the offspring receiving one copy from the Sire and one from the Dam. The two forms are: SC – This form causes scurring and the capitalisation indicates that ...
here - FasterDB
here - FasterDB

... Figure 12. Comparison of PTB Binding Sites between Human exon 13 and its orthologous exon in the mouse genome (exon 15) among the WNK gene (A). CLIP-seq data for PTB at the exon level (B). Exon Arrays visualization when PTB is depleted in the Human (C) and Mouse (D). A. For each exon and 200 nucleot ...
Physical Adaptation
Physical Adaptation

... ulcer, diverticulitis and gall bladder disease. He studied marine life and flora and fauna of South America for the five year trip. ...
Lab #2
Lab #2

... complement is queried (or available for annotation), only use that population as background. • To test for enrichment of more than one independent types of annotation (red vs black and circle vs square), apply Fisher’s exact test separately for each type. ***More on this later*** Module 2: Analyzing ...
Non-random Allelic Variation
Non-random Allelic Variation

... trials the winning boat will have all the same oarsmen. A crew member finally chosen will have been grouped with both good and inferior ones at different times, but on average his performance has contributed more to the trials than one who was not chosen. Natural selection within populations can be ...
The Spandrels of San Marco and the Panglossian Paradigm: A
The Spandrels of San Marco and the Panglossian Paradigm: A

... being such an undogmatic and ecumenical chap. We maintain that alternatives to selection for best overall design have generally been relegated to unimportance by this mode of argument. Have we not all heard the catechism about genetic drift: it can only be important in populations so small that they ...
Lecture 21: Gene Set Enrichment Analysis
Lecture 21: Gene Set Enrichment Analysis

... Calculate an Enrichment Score: • Rank genes by their expression difference • Compute cumulative sum over ranked genes: • Increase sum when gene in set, decrease it otherwise. • Magnitude of increment depends on correlation of gene ...
Kin selection is the key to altruism Kevin R. Foster
Kin selection is the key to altruism Kevin R. Foster

... structure of any one species had been formed for the exclusive good of another species, it would annihilate my theory.’ [16]. We know of no such examples for either kin selection or natural selection. It is perhaps surprising, therefore, that both of Wilson’s papers claim that altruism can evolve wi ...
Module 1: Introduction
Module 1: Introduction

... • Set of biological phrases (terms) which are applied to genes: – protein kinase – apoptosis – Membrane ...
Slide 1
Slide 1

... Interpreting Gene Lists • My cool new screen worked and produced 1000 hits! …Now what? ...
Extensions to Mendel`s Law
Extensions to Mendel`s Law

... • Dominance relations affect phenotype y and have no bearing on the segregation of alleles. • Alleles still segregate randomly. • Gene products control expression of phenotypes differently. • Mendel’s M d l’ law l off segregation ti still till applies. li • Interpretation p of p phenotype/genotype y ...
Altruism, spite and greenbeards - Department of Zoology, University
Altruism, spite and greenbeards - Department of Zoology, University

... contentious. Here, we show how recent work has resolved three key debates, helping clarify how Hamilton’s theoretical overview links to real-world examples, in organisms ranging from bacteria to humans: Is the evolution of extreme altruism, represented by the sterile workers of social insects, drive ...
this PDF file - Undergraduate Science Journals
this PDF file - Undergraduate Science Journals

... Authors: Kassidy Ford, Dr. Gilbert John* Department of Microbiology and Molecular Genetics, Oklahoma State University ...
Tutorial - Ensembl
Tutorial - Ensembl

... assembly (NCBI 36 is the most recent human genome sequence from the Human Genome Project.) The chromosome number is then indicated (7) and the base pairs (100155759100159857). The final 1 shows the sequence is the forward strand of the chromosome. A -1 would indicate the reverse strand. Most pages i ...
A Predictive Based Regression Algorithm for Gene Network
A Predictive Based Regression Algorithm for Gene Network

... Stéphane Guerrier1 , Nabil Mili2 & Samuel Orso2 ...
Comparative Evolution of Duplicated Ddx3 Genes in Teleosts
Comparative Evolution of Duplicated Ddx3 Genes in Teleosts

... Brunet et al. 2006; Amores et al. 2011). Teleost-specific genome duplication (TGD) likely provided gene copies that contributed to evolutionary radiation and phenotypic diversification of teleost fishes. Studies on TGD-derived gene duplicates that evolved distinct physiological or developmental functio ...
Targeted gene repair – in the arena
Targeted gene repair – in the arena

... in yeast (13, 14) (see “Clinical use of gene repair: are we there yet?”). We now believe that the chimera directs nucleotide exchange in two distinct phases: DNA pairing and DNA repairing. The first phase consists of protein-promoted DNA hybridization between the vector (chimera) and its complementa ...
wp8 lengger
wp8 lengger

... What is the best search term to look for in a database that describes the phenotype (e.g. obesity / obeseness / adiposity / adiposeness / overweight); do different search terms always have different meanings? Are there any synonyms or antonyms? Are there any mutants available (EMMA, cryo banks) or d ...
Models of Selection, Isolation, and Gene Flow in Speciation
Models of Selection, Isolation, and Gene Flow in Speciation

... of both functional and genetic analyses because they represent a relatively simple basis for the evolution of reproductive isolation and speciation in marine organisms that lack complex behavioral interactions between male and female individuals (compared to organisms like terrestrial vertebrates an ...
Börjeson–Forssman–Lehmann syndrome: defining
Börjeson–Forssman–Lehmann syndrome: defining

... outside of this interval, but its putative interaction with the product of Ihtw1 (interspecific hybrid testis weight 1) from this interval was discussed [7]. Another candidate gene from the BFLS interval in Xq26 is the guanine nucleotide exchange factor ARHGEF6. A sequence analysis of this gene in i ...
Documentation for Candidate Gene Prioritization
Documentation for Candidate Gene Prioritization

... This script performs all of the counting, testing, and scoring steps. It uses R (it was written under R version 2.3.1 and is fully compatible with R version 2.4.0). It requires the files ‘GOannotation.txt’, ‘expcounts.txt’, and ‘correl.txt’. The script reads in the file ‘correl.txt’, which contains ...
Yang (2002) - molecularevolution.org
Yang (2002) - molecularevolution.org

... on a single branch, the approach avoids averaging over long time periods, and it identified two lineages under positive selection. Zhang et al. [17,18] were concerned about the reliability of the normal approximation and suggested the use of Fisher’s exact test applied to counts of differences. (An ...
Module 1: Introduction
Module 1: Introduction

... • Set of biological phrases (terms) which are applied to genes: – protein kinase – apoptosis – Membrane ...
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The Selfish Gene

The Selfish Gene is a book on evolution by Richard Dawkins, published in 1976. It builds upon the principal theory of George C. Williams's first book Adaptation and Natural Selection. Dawkins used the term ""selfish gene"" as a way of expressing the gene-centred view of evolution as opposed to the views focused on the organism and the group, popularising ideas developed during the 1960s by W. D. Hamilton and others. From the gene-centred view follows that the more two individuals are genetically related, the more sense (at the level of the genes) it makes for them to behave selflessly with each other. This should not be confused with misuse of the term along the lines of a selfishness gene.An organism is expected to evolve to maximise its inclusive fitness—the number of copies of its genes passed on globally (rather than by a particular individual). As a result, populations will tend towards an evolutionarily stable strategy. The book also coins the term meme for a unit of human cultural evolution analogous to the gene, suggesting that such ""selfish"" replication may also model human culture, in a different sense. Memetics has become the subject of many studies since the publication of the book.In the foreword to the book's 30th-anniversary edition, Dawkins said he ""can readily see that [the book's title] might give an inadequate impression of its contents"" and in retrospect thinks he should have taken Tom Maschler's advice and called the book The Immortal Gene.
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