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Anderson 2014 Cochrane Overview
Anderson 2014 Cochrane Overview

... Many definitions of cardiac rehabilitation (CR) have been proposed. The following definition encompasses the key concepts of CR: “The coordinated sum of activities required to influence favourably the underlying cause of cardiovascular disease, as well as to provide the best possible physical, menta ...
Cardiovascular magnetic resonance: A key to
Cardiovascular magnetic resonance: A key to

... “Sooner or later all interesting cardiac patients will get an MR scan.” This often quoted statement is no longer true because of two reasons. First, all patients are interesting. Even most common diseases are associated with a huge variety of different complaints, signs and symptoms. This is one of ...
General Anesthesia Fatal and non fatal car
General Anesthesia Fatal and non fatal car

... All patients were examined by an anesthesiologist prior to anesthesia. Basic safety monitoring included: continuous electrocardiogram display, automatic non invasive blood pressure, and pulse oximetry. When regional anesthesia was associated with sedation, or general anesthesia was performed, capnog ...
Effect of obesity and regional adiposity on the QTc interval
Effect of obesity and regional adiposity on the QTc interval

... volume, using a 3 liter calibrated syringe, prior to use. Gas analyzers were calibrated using certi®ed calibraÇ O2 max was tion gases prior to exercise testing. V Ç attained when VO2 did not increase (> 150 ml/min) despite increasing exercise work rate or if the respiratory exchange ratio (R) was gr ...
Mutations in the cardiac L-type calcium channel associated with
Mutations in the cardiac L-type calcium channel associated with

... to pathogenesis of these syndromes. We tested the hypothesis that mutations in LTCC genes are relatively common among probands diagnosed with these syndromes. We also examined the hypothesis that LTCC mutation-mediated BrS associated with a normal QTc is attributable to additional genetic variations ...
Biomarkers of Acute Coronary Syndrome and Heart Failure
Biomarkers of Acute Coronary Syndrome and Heart Failure

... close communication with local physician and other caregivers, as well as with the administrators responsible for each area. Collaboration with manufacturers and communication of clinical need as articulated in the guidelines are also critical for proper implementation. Many of these issues are of p ...
Amiodarone monitoring protocol - Derbyshire Medicines Management
Amiodarone monitoring protocol - Derbyshire Medicines Management

... Amiodarone is a class III antiarrhythmic drug (Vaughn-Williams classification) that reduces the incidence of arrhythmias by increasing the duration and refractory period of the cardiac action potential prolonging the QT interval. It also slows heart rate and cardiac action potential conduction throu ...
Fulltext - Jultika
Fulltext - Jultika

... oscillations of the heart rate (HR) calculated from the electrocardiogram (ECG). These oscillations are termed as heart rate variability (HRV). HRV is a physiological phenomenon driven mainly by the balance of the two branches of the autonomic nervous system, sympathetic and parasympathetic. Measure ...
Cardiac Endothelial-Myocardial Signaling
Cardiac Endothelial-Myocardial Signaling

... cardiac function, in particular, at the endocardium and in the myocardial capillaries where endothelial cells directly interact with adjacent cardiomyocytes. The emerging field of targeted gene manipulation has led to the contention that cardiac endothelial-cardiomyocytal interaction is a prerequisi ...
Print - Circulation
Print - Circulation

... mains of cadherin.3 ␣-Catenins are key cytoplasmic molecules that are thought to indispensably link the cytoplasmic domain of cadherin to the actin cytoskeleton.16 ␣-Catenins are thought to provide this link by binding to ␤- or ␥-catenin through their N-terminal domain and to actin directly through ...
2013 ESC Guidelines on cardiac pacing and cardiac
2013 ESC Guidelines on cardiac pacing and cardiac

... The experts of the writing and reviewing panels completed Declaration of Interest forms where real or potential sources of conflicts of interest might be perceived. These forms were compiled into one file and can be found on the ESC website (http://www.escardio.org/ guidelines). Any changes in decla ...
impact of isoprenaline and caffeine on development of left
impact of isoprenaline and caffeine on development of left

... which frequently occurs as a result of an elevated resistance within the circulatory system. This increase in mass of the myocardium results from a chronically raised workload on the heart (1) and is taken as an early sign of cardiomyopathy, which ultimately may lead to symptomatic heart failure. LV ...
2013 ESC Guidelines on cardiac pacing and cardiac
2013 ESC Guidelines on cardiac pacing and cardiac

... The experts of the writing and reviewing panels completed Declaration of Interest forms where real or potential sources of conflicts of interest might be perceived. These forms were compiled into one file and can be found on the ESC website (http://www.escardio.org/ guidelines). Any changes in decla ...
Ventricular septal defect - ePrints
Ventricular septal defect - ePrints

... not all defects are anatomically the same. The phenotypic differences are important, not only when determining the optimal approach to correction, but also for subsequent genetic counseling. This is because the morphogenesis of the various types is fundamentally different [9]. In terms of phenotypic ...
Perioperative Assessment of Diastolic Dysfunction
Perioperative Assessment of Diastolic Dysfunction

... has been used to diagnose perioperative diastolic dysfunction during cardiac surgery.11–15 However, other than being a predictor of difficult weaning from cardiopulmonary bypass,11,12 the impact of perioperative diastolic dysfunction on short- and long-term postoperative morbidity and mortality in c ...
ESC Guidelines on Cardiac Pacing and CRT
ESC Guidelines on Cardiac Pacing and CRT

... The experts of the writing and reviewing panels completed Declaration of Interest forms where real or potential sources of conflicts of interest might be perceived. These forms were compiled into one file and can be found on the ESC website (http://www.escardio.org/ guidelines). Any changes in decla ...
Chapter 4 Atrial Mechanisms
Chapter 4 Atrial Mechanisms

... May be irregular as pacemaker site shifts from SA node to ectopic atrial locations and AV junction ...
Right Ventricular Ejection Fraction Angiography
Right Ventricular Ejection Fraction Angiography

... curve were used. Beats with low activity or contaminated by activity arising from the lung were excluded from analysis. In general, three or four cardiac cycles were used for deriving the ejection fraction. In five patients, ejection fraction was calculated from only two beats. In each patient, the ...
Initiation of cardiac differentiation occurs in the
Initiation of cardiac differentiation occurs in the

... mesoderm from avian embryos have supported an inductive role for endoderm in cardiac differentiation using beating and tissuespecific protein expression as an assay (Sugi and Lough, 1994; Antin et al., 1994). In addition, the recent isolation of novel homeobox genes expressed specifically in early h ...
Targeted Neonatal Echocardiography in the Neonatal Intensive
Targeted Neonatal Echocardiography in the Neonatal Intensive

... TNE can be a useful clinical adjunct to the overall assessment of the cardiovascular status of preterm and term neonates during normal and abnormal transition to extrauterine life. Ventricular systolic function can be noninvasively assessed using qualitative and quantitative methods; the direction a ...
Atrial Septal Defect and Atrial Fibrillation: The Known and Unknown
Atrial Septal Defect and Atrial Fibrillation: The Known and Unknown

... the interatrial defect with significant hypoxia and cyanosis (Eisenmenger syndrome).20 The most common initial presenting symptoms of ASD are exertional dyspnea or fatigue. Patients may then develop AF, decompensated right heart failure, occasionally, paradoxical embolus or transient ischemic attack ...
An Analysis of Pacemaker Activity in the Canine Right Atrium
An Analysis of Pacemaker Activity in the Canine Right Atrium

... the upper part of the node shifted the point of initial negativity to the lower part. The now-classical concept of a single site of origin of pacemaker activity in the sinoatrial node has been accepted for over 50 years. ...
Extraction of Response Waveforms of Heartbeat and Blood Pressure
Extraction of Response Waveforms of Heartbeat and Blood Pressure

... normality test. Therefore, we assumed that the indices were normally distributed and applied the t test as well as the recent studies [35, 36]. Since time variation of CV responses would be expected to clarify with high accuracy by the proposed method, statistical differences between data at the tim ...
Age-related sensitivity to nicotine for inducible atrial tachycardia and
Age-related sensitivity to nicotine for inducible atrial tachycardia and

... We studied male Fischer 344 rats, a strain that has been extensively used as a model of aging without the presence of other confounding factors such as coronary, vascular, or valvular abnormalities that often accompany aging (17, 18). Twelve male rats consisting of six young (2–3 mo old) and six old ...
Heart rate as a marker of incidence and prognosis of cardiovascular
Heart rate as a marker of incidence and prognosis of cardiovascular

... I used CALIBER, a linked electronic health records (EHR) platform that links primary and secondary care data, myocardial infarction disease registry and mortality data. Additionally, to establish a clinical cohort of people with CAD, I consented, recruited and collected anthropometric and biomarker ...
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Electrocardiography



Electrocardiography (ECG or EKG*) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on a patient's body. These electrodes detect the tiny electrical changes on the skin that arise from the heart muscle depolarizing during each heartbeat.In a conventional 12 lead ECG, ten electrodes are placed on the patient's limbs and on the surface of the chest. The overall magnitude of the heart's electrical potential is then measured from twelve different angles (""leads"") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an electrocardiogram (abbreviated ECG or EKG).During each heartbeat, a healthy heart will have an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads out through the atrium, passes through the atrioventricular node down into the bundle of His and into the Purkinje fibers spreading down and to the left throughout the ventricles. This orderly pattern of depolarization gives rise to the characteristic ECG tracing. To the trained clinician, an ECG conveys a large amount of information about the structure of the heart and the function of its electrical conduction system. Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers.
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