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McCance: Pathophysiology, 6th Edition
McCance: Pathophysiology, 6th Edition

... thyroid antibodies, and gradual loss of thyroid function. Autoimmune thyroiditis occurs in those individuals with a genetic susceptibility to an autoimmune mechanism that causes thyroid damage and eventual hypothyroidism. 15. Hypothyroidism also can be caused by hypothalamic-pituitary dysfunction in ...
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• Two hormones are produced: (vasopressin) Thyroid Gland The

... It secretes one hormone Adrenal Glands • The adrenal glands are closely associated with the kidneys The gland sits like a cap on each kidney Hormones are secreted from two different areas of the gland, the adrenal cortex and the adrenal medulla ...
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Diagnosis and treatment of Graves` disease with particular emphasis
Diagnosis and treatment of Graves` disease with particular emphasis

... Ultrasound examination on thyroid, belonging to the screening examinations, helps in its diagnosis. It is inexpensive, non-invasive, repeatable, which allows diagnosing breast-feeding mothers, pregnant women giving immediate results and documentation in the form of photos of tested thyroid. The ultr ...
Vertebrate Zoology BIOL 322/Endocrine System Ch 34 final version
Vertebrate Zoology BIOL 322/Endocrine System Ch 34 final version

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thyroid gland - Uplift Education
thyroid gland - Uplift Education

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The Endocrine System - Leaving Cert Biology
The Endocrine System - Leaving Cert Biology

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Hypothyroid Disease Brochure
Hypothyroid Disease Brochure

... If your pet has clinical signs or symptoms that may be consistent with hypothyroid disease, a T4 blood test should be performed in the office. If this test shows normal levels of T4, your pet likely does not have a thyroid problem, and other tests will be suggested to determine the cause of your pet ...
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Thyroid hormones and aging

... to 8 times more common in women than men, varies from 0.1 to 2%, with an increased prevalence of up to 5% in subjects over 60 years of age.1,50 Hypothyroidism in the elderly is often atypical and lacks the classic symptoms seen in younger patients.1 This is due to a more insidious onset, the co-exis ...
thyroid gland - Pharmacy Fun
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Production, Regulation, and Action of Thyroid Hormones

... When not bound to hormone, the thyroid hormone receptor binds to target DNA (TRE on 5’ flanking region). It is associated with corepressor proteins that cause DNA to be tightly wound and inhibit transcription. Binding of hormone causes a conformational change, resulting in loss of corepressor bind ...
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Fig 7-2 Hormones

... Autoantibodies (TSI) bind to TSH receptor and stimulate thyroid hormone production This activation by TSI is not subject to the normal negative feedback loop. Left exophthalmus in Graves disease ...
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Endocrine Physiology

... ◦ More common in women ◦ Symptoms: strained and tense facial expression, nervous, irritability ◦ Goiter -due to iodine deficiency, dry/itchy skin, dry/brittle hair, constipation, muscle cramps ◦ Major cause due to inflammation of the thyroid which destroys the ability of the gland to make thyroxine ...
Endocrine System - Westhampton Beach Elementary School
Endocrine System - Westhampton Beach Elementary School

... • a hormone is a chemical produced by a gland that affects the activities of other organs or tissues ...
A Brief Look at Our Major Hormones
A Brief Look at Our Major Hormones

... women in smaller quantities. It is responsible for firm muscles and a healthy libido in both sexes, and has other important roles to play in the body as well. For women, levels of this hormone usually drop before or during menopause. Men also pass through "andropause" which is caused by a lessening ...
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Hypothalamic-anterior-pituitary System

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Thyroid Testing In Dogs
Thyroid Testing In Dogs

... unknown causes). The disease can occur in either sex and usually becomes apparent in young adults (1-3 years of age) or middle-aged dogs (4-9 years of age). Clinical signs may include hair loss, seborrhea, bacterial skin infections, excessive skin pigmentation, lethargy, obesity, muscle or nerve wea ...
PPT #3 Human Body Endocrine System
PPT #3 Human Body Endocrine System

... What does the Endocrine System Do? • Uses chemical signals for cell to cell communication – this is why it is slower than the nervous system ...
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Hyperthyroidism



Hyperthyroidism, also known as over active thyroid and hyperthyreosis, is the condition that occurs due to excessive production of thyroid hormone by the thyroid gland. Thyrotoxicosis is the condition that occurs due to excessive thyroid hormone of any cause and therefore includes hyperthyroidism. Some, however, use the terms interchangeably. Signs and symptoms vary between people and may include irritability, muscle weakness, sleeping problems, a fast heartbeat, poor tolerance of heat, diarrhea, enlargement of the thyroid, and weight loss. Symptoms are typically less in the old and during pregnancy. An uncommon complication is thyroid storm in which an event such as an infection results in worsening symptoms such as confusion and a high temperature and often results in death. The opposite is hypothyroidism, when the thyroid gland does not make enough thyroid hormone.Graves' disease is the cause of about 50% to 80% of case of hyperthyroidism in the United States. Other causes include multinodular goiter, toxic adenoma, inflammation of the thyroid, eating too much iodine, and too much synthetic thyroid hormone. A less common cause is a pituitary adenoma. The diagnosis may be suspected based on signs and symptoms and then confirmed with blood tests. Typically blood tests show a low thyroid stimulating hormone (TSH) and raised T3 or T4. Radioiodine uptake by the thyroid, thyroid scan, and TSI antibodies may help determine the cause.Treatment depends partly on the cause and severity of disease. There are three main treatment options: radioiodine therapy, medications, and thyroid surgery. Radioiodine therapy involves taking iodine-131 by mouth which is then concentrated in and destroys the thyroid over weeks to months. The resulting hypothyroidism is treated with synthetic thyroid hormone. Medications such as beta blockers may control the symptoms and anti-thyroid medications such as methimazole may temporarily help people while other treatments are having effect. Surgery to remove the thyroid is another option. This may be used in those with very large thyroids or when cancer is a concern. In the United States hyperthyroidism affects about 1.2% of the population. It occurs between two and ten times more often in women. Onset is commonly between 20 and 50 years of age. Overall the disease is more common in those over the age of 60 years.
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