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Biol 155 Human Physiology
Biol 155 Human Physiology

... The half-life is the time required for the hormone to loose half of its original effectiveness (or drop to half of its original concentration. ...
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139 Endocrine System

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... Chromophobe cells do not demonstrate cytoplasmic staining, and appear as nuclei surrounded by a relatively clear area. Notice that the cells are often arranged in islands or cluster and that various combinations of the three cell types may be seen adjacent to each other. They are separated by interv ...
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... 2. Describe the endocrine glands and the hormones each secretes. 3. Compare endocrine and exocrine glands. 4. Explain the difference between steroid hormones and nonsteroid hormones. 5. Explain how the endocrine system maintains homeostasis. 6. Identify the functions of the major endocrine glands: p ...
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Adrenal gland



The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys and consist of a series of layers with different structure and functions. Each gland has an outer cortex which produces steroid hormones and an inner medulla. The adrenal cortex itself is divided into three zones: zona glomerulosa, the zona fasciculata and the zona reticularis.The adrenal cortex produces a class of steroid hormones called corticosteroids, named according to their effects. Mineralocorticoids, produced in the zona glomerulosa, help in the regulation of blood pressure and electrolyte balance. Glucocorticoids such as cortisol are synthesized in the zona fasciculata; their functions include the regulation of metabolism and immune system suppression. The innermost layer of the cortex, the zona reticularis, produces androgens that are converted to fully functional sex hormones in the gonads and other target organs. The production of steroid hormones is called steroidogenesis, and involves a number of reactions and processes that take place in cortical cells. The medulla produces the catecholamines adrenaline and noradrenaline, which function to produce a rapid response throughout the body in stress situations.A number of endocrine diseases involve dysfunctions of the adrenal gland. Overproduction of corticosteroid hormones leads to Cushing's syndrome, whereas insufficient production is associated with Addison's disease. Congenital adrenal hyperplasia is a genetic disease produced by dysregulation of endocrine control mechanisms. A variety of tumors can arise from adrenal tissue and are commonly found in medical imaging when searching for other diseases.
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