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Medical Biology
Medical Biology

... pathogenic bacteria by secreting toxic substances or by competing with pathogenic bacteria for nutrients or attachment to cell surfaces Some epithelia produce mucus which also acts as a barrier against infections. If ...
Lines of Defense and Immunity
Lines of Defense and Immunity

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Lec

... II- Helper T cells are the T cells that act as the "directors" or "managers" of the immune system. Once activated, they circulate through the body, recruiting other cells to fight the invaders. For example, helper T cells interact directly with B cells (that have already attached to antigens), prod ...
Immunity
Immunity

... any injurious stress is called immune system Te stress may be intrinsic (inside of the body) or extrinsic (out side of the body) Antigen: is any substance that elicits an immune response, from a virus to a sliver. Antibody: Proteins secreted by the Lymphocytes in response to antigen ...
7.5 Immune response – questions and answers Q1. Bk Ch7 S7.6 Q1
7.5 Immune response – questions and answers Q1. Bk Ch7 S7.6 Q1

... into a person rather than the person producing the antibodies. Active immunity is long lasting because the body has produced the antibodies itself and therefore retains a ‘memory’ of the pathogen. However, when a person is immunised against a particular pathogen, for example the measles virus, they ...
11-1notes
11-1notes

...  B-cells fused with cancer cells to produce hybridomas  Hybridomas divide indefinitely and produce antibodies  Hybridomas can be used for diagnosis and treatment ...
chapter16
chapter16

... immediately engage the pathogen and delay its actions long enough for the adaptive response to join the battle ...
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PowerPoint **

... Antigen from the microbe (nonself molecule) ...
microbio 7 [4-20
microbio 7 [4-20

... 15. What are the two methods of dendritic cell sampling?  Dendritic cells sample the environment via phagocytosis with clathrin-coated pits  Or via macropinocytosis and the formation of phagolysozomes 16. What dendritic surveilance system are pathogen-associated molecular patterns (PAMPs) associat ...
Immunology Review
Immunology Review

... • B cells divide into plasma cells or memory cells. – Plasma cells produce and secrete antibody. – The antibody produced is specific for one antigenic determinant! – Memory cells recall previous encounter with foreign antigen. Persist in circulating lymphocyte pool for months up to years. ...
APCh43ImmunityDiagrams_Terms
APCh43ImmunityDiagrams_Terms

... Type of WBC, originates from stem cells in bone marrow, general term Circulate in blood, are attracted by signals, engulf & destroy pathogens Lymphocytes that mature & remain in blood, release chemicals to destroy abnormal cells Found beneath mucousal surfaces, defend against multicellular invaders ...
Disorders of the Immune System and Vaccination
Disorders of the Immune System and Vaccination

... unfamiliar protein group attached to it and the body mounts an immune response to get rid of it. – Complement and other inflammatory cells are activated that cause damage to surrounding tissues as they try to remove the deposited immune complex. ...
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Immune

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Types of immunity :- 1- innate immunity 2

... - early , limited specifity . - the first line of defense . - not have memory . *Cells of innate immunity :1- Neutrophil 2- eosinophil 3- basophil 4- NK cells ( natural killer ) 5- macrophage 6- mast cells . *Adaptive immunity :- antigen dependent ( require antigen ) - variable - later , highly spec ...
43 - GEOCITIES.ws
43 - GEOCITIES.ws

... 4. Rationalize the four cardinal signs of an acute inflammatory response. a. Histamine and kinins released b. Increased blood flow causes redness and heat c. Leaky blood vessels cause swelling and pain 5. Describe the roles of chemotaxis and diapedesis in the inflammatory response. a. Histamines and ...
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File

... After antigen receptors bind to the epitope of an antigen, B-cells divide and also release antibodies ...
The Immune System and Disease Chapter 40 Page 1030
The Immune System and Disease Chapter 40 Page 1030

IMMUNOBIOLOGY (PCB4233 - 3 credits) Instructor Dr. Mauricio
IMMUNOBIOLOGY (PCB4233 - 3 credits) Instructor Dr. Mauricio

... E-mail: [email protected] (Always put PCB4233 on the subject line) Office hours: Tuesday and Thursday from 2:00 – 4:00 pm I do not check email or respond to phone calls after 5:30PM ...
adaptive immune system
adaptive immune system

... Lymphocytes are responsible for the specific immune response ...
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antibodies_lymph

... Antibodies and Antigens • Antigens are foreign substances that are recognized by the immune system • They are usually proteins or polysaccharides (such as those found on cell membranes or the outer coat of a virus) ...
Week 1
Week 1

Major components of blood -made up of the following things
Major components of blood -made up of the following things

... White blood cells - white blood cells defend the body against viruses, bacteria, and other foreign invaders. They do this by engulfing invaders or by producing antibodies. There are 6000 to 9000 white blood cells per cc. of blood. Platelets - look like plates, are colorless, round or biconcave, are ...
Lymphatic Test Review sheet
Lymphatic Test Review sheet

... a. recovering from the chickenpox naturally acquired passive immunity b. receiving the polio vaccine artificially acquired active immunity c. receiving an injection of gamma globulin artificially acquired passive immunity d. receiving antibodies through the placenta artificially acquired active immu ...
Medical Immunology
Medical Immunology

... unique to individual tumors, whereas others are shared among tumors of the same type. ...
Immunity
Immunity

... Phagocytes are large white cells that can engulf and digest foreign invaders. They include monocytes, which circulate in the blood, and macrophages, which are found in tissues throughout the body, as well as neutrophils, cells that circulate in the blood but move into tissues where they are needed. ...
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Polyclonal B cell response



Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.
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