Chapter 14: Resistance and the Immune System: Innate Immunity
... • This can cause convulsions and death Natural Killer Cells Recognize and Kill Abnormal Cells • NK cells are formed in the bone marrow, and migrate to: • tonsils • lymph nodes • spleen ...
... • This can cause convulsions and death Natural Killer Cells Recognize and Kill Abnormal Cells • NK cells are formed in the bone marrow, and migrate to: • tonsils • lymph nodes • spleen ...
chapter16
... inserted into the lumen of the ER MHC I proteins bind to the peptides and then are displayed on the cell’s surface CD8+ Tc cells recognize these microbial peptides and kill the cell Puncturing holes in the membrane with perforin Inducing a death signal that causes DNA fragmentation ...
... inserted into the lumen of the ER MHC I proteins bind to the peptides and then are displayed on the cell’s surface CD8+ Tc cells recognize these microbial peptides and kill the cell Puncturing holes in the membrane with perforin Inducing a death signal that causes DNA fragmentation ...
Immune System Powerpoint
... Function in both humoral & cell-mediated immunity Stimulated by antigen presenting cells (APCs) T cell surface protein CD4 enhances activation Cytokines secreted (stimulate other lymphocytes): a) interleukin-2 (IL-2): activates B cells and cytotoxic T cells b) interleukin-1 (IL-1): activates helper ...
... Function in both humoral & cell-mediated immunity Stimulated by antigen presenting cells (APCs) T cell surface protein CD4 enhances activation Cytokines secreted (stimulate other lymphocytes): a) interleukin-2 (IL-2): activates B cells and cytotoxic T cells b) interleukin-1 (IL-1): activates helper ...
Blood Groups and Immunogenetics
... Antigens are molecules (usually proteins) that differ in some way from our own natural proteins. The proteins on one persons' cell surfaces will usually be recognized as "foreign" to another individual which accounts for rejection in many organ transplant attempts. The system is also involved in rec ...
... Antigens are molecules (usually proteins) that differ in some way from our own natural proteins. The proteins on one persons' cell surfaces will usually be recognized as "foreign" to another individual which accounts for rejection in many organ transplant attempts. The system is also involved in rec ...
m1/98 summative mcq
... A type IV is also known as anaphylactoid reaction A type IV is responsible for contact dermatitis A type II is an immune complex antibody mediated reaction Type III immune complexes cause a vasculitis A type I reaction is associated with food allergies ...
... A type IV is also known as anaphylactoid reaction A type IV is responsible for contact dermatitis A type II is an immune complex antibody mediated reaction Type III immune complexes cause a vasculitis A type I reaction is associated with food allergies ...
Slide - Smith Lab
... Introduction of foreign antigens into the anterior chamber, subretinal space And vitreous cavity induces systemic tolerance to these antigens Mediated by the generation of Tregulatory cells ...
... Introduction of foreign antigens into the anterior chamber, subretinal space And vitreous cavity induces systemic tolerance to these antigens Mediated by the generation of Tregulatory cells ...
Cells of the Immune System
... o Neutralize – block or neutralize bacterial toxins. Prevent some viruses from attaching to body cells. o Immobilize – attack flagella and cilia of bacteria. o Agglutinate – cross-link two pathogens together…phagocytes come in after and ingest agglutinated pathogens. o Activate Complement o E ...
... o Neutralize – block or neutralize bacterial toxins. Prevent some viruses from attaching to body cells. o Immobilize – attack flagella and cilia of bacteria. o Agglutinate – cross-link two pathogens together…phagocytes come in after and ingest agglutinated pathogens. o Activate Complement o E ...
Secondary Lymphoid Organs of the Immune System
... patches of the gut, and appendix. The secondary lymphoid organs are where mature T and B cells have the opportunity to bind antigen and undergo further antigen dependent differentiation. The active immune response both cell mediated and humoral immunity begins. All of the secondary lymphoid organs a ...
... patches of the gut, and appendix. The secondary lymphoid organs are where mature T and B cells have the opportunity to bind antigen and undergo further antigen dependent differentiation. The active immune response both cell mediated and humoral immunity begins. All of the secondary lymphoid organs a ...
PowerPoint
... antigens are soluble molecules and the immune complex settles out of solution • Agglutination reaction occurs when cells or particles are cross-linked – the immune complex formed is more readily phagocytosed in vivo than are free antigens – caused by agglutinin antibodies ...
... antigens are soluble molecules and the immune complex settles out of solution • Agglutination reaction occurs when cells or particles are cross-linked – the immune complex formed is more readily phagocytosed in vivo than are free antigens – caused by agglutinin antibodies ...
Mitosis & Cancer
... Travel to another part of body via bloodstream or lymphatic system (a collection of vessels that carry fluid and immune system cells). ...
... Travel to another part of body via bloodstream or lymphatic system (a collection of vessels that carry fluid and immune system cells). ...
Monoclonal Antibodies as a novel class of cancer therapeutics
... from the first use in humans to regulatory approval: 29% for chimeric Abs, 25% for humanized Abs (only 11% small-molecule drug). Abs are generally well tolerated by humans, although infusion reaction (first dose) are common but manageable (e.g.: rituximab). Their clinical potential can readily be in ...
... from the first use in humans to regulatory approval: 29% for chimeric Abs, 25% for humanized Abs (only 11% small-molecule drug). Abs are generally well tolerated by humans, although infusion reaction (first dose) are common but manageable (e.g.: rituximab). Their clinical potential can readily be in ...
File
... A vaccine is a dose of a pathogen destroyed so it is no longer harmful, but it still has the antigens present. These antigens trigger an immune response. ...
... A vaccine is a dose of a pathogen destroyed so it is no longer harmful, but it still has the antigens present. These antigens trigger an immune response. ...
Chapter 43 The Body`s Defenses
... • Immune cells are monitored to assure that they do not have receptors for proteins already present in the body. If they do, they are destroyed by programmed cell death. The _______ to distinguish self from _______ is critical to survival. The immune system exhibits the critical feature of _____-___ ...
... • Immune cells are monitored to assure that they do not have receptors for proteins already present in the body. If they do, they are destroyed by programmed cell death. The _______ to distinguish self from _______ is critical to survival. The immune system exhibits the critical feature of _____-___ ...
HIV/AIDS - Artec Inc.
... White blood cells circulate in the blood system, immunosurveilling, identifying non-self cells and cellular debris. When devouring takes place, white blood cells churn out a strong chemical signal in the form of Cytokines, such as Interleukin (IL). IL in turn stimulates the immune system to massivel ...
... White blood cells circulate in the blood system, immunosurveilling, identifying non-self cells and cellular debris. When devouring takes place, white blood cells churn out a strong chemical signal in the form of Cytokines, such as Interleukin (IL). IL in turn stimulates the immune system to massivel ...
... An immune response – white blood cells and antibodies attack a virus. Notice that the antibody protein has to have a specific __________________________ to fit with the antigen. This is another example of the _____________________________________ concept. This is also why vaccines are specific for a ...
Document
... the immune system is defective • Inherited immunodeficiences (genetic) are the most common IgA deficiency the most common of these (1 in 800) The rest are rare (1 in 10,000) ...
... the immune system is defective • Inherited immunodeficiences (genetic) are the most common IgA deficiency the most common of these (1 in 800) The rest are rare (1 in 10,000) ...
The Immune system
... is false? • A) The genome of HIV consists of RNA. • B) HIV attacks helper T cells. • C) New HIV are produced inside helper T cells. • D) HIV is transmitted by body fluids transporting infected cells. • E) Some antibiotics have proven effective in combating the spread of AIDS. ...
... is false? • A) The genome of HIV consists of RNA. • B) HIV attacks helper T cells. • C) New HIV are produced inside helper T cells. • D) HIV is transmitted by body fluids transporting infected cells. • E) Some antibiotics have proven effective in combating the spread of AIDS. ...
The Immune System
... Can be foreign to the body, such as bacteria, viruses, and parasites, or can be part of the body's immune mechanism ...
... Can be foreign to the body, such as bacteria, viruses, and parasites, or can be part of the body's immune mechanism ...
the-immune-system-part-4-teacher-notes
... Antihistamines: drugs for allergies that reduce symptoms Severe allergies may trigger anaphylactic shock o Swelling, breathing problems, potential death o Adrenaline injection reduces symptoms (“Epipen”) ...
... Antihistamines: drugs for allergies that reduce symptoms Severe allergies may trigger anaphylactic shock o Swelling, breathing problems, potential death o Adrenaline injection reduces symptoms (“Epipen”) ...
BIOL 495: Introduction to Immunology
... Specific immunities are referred to as our Adaptive immunity for which there are 2 branches: Humoral immunity Cell-mediated immunity ...
... Specific immunities are referred to as our Adaptive immunity for which there are 2 branches: Humoral immunity Cell-mediated immunity ...
Cancer immunotherapy
Cancer immunotherapy (immuno-oncology) is the use of the immune system to treat cancer. Immunotherapies fall into three main groups: cellular, antibody and cytokine. They exploit the fact that cancer cells often have subtly different molecules on their surface that can be detected by the immune system. These molecules, known as cancer antigens, are most commonly proteins, but also include molecules such as carbohydrates. Immunotherapy is used to provoke the immune system into attacking the tumor cells by using these antigens as targets.Antibody therapies are the most successful immunotherapy, treating a wide range of cancers. Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. In normal physiology the immune system uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to cancer antigens are used to treat cancer. Cell surface receptors are common targets for antibody therapies and include the CD20, CD274, and CD279. Once bound to a cancer antigen, antibodies can induce antibody-dependent cell-mediated cytotoxicity, activate the complement system, or prevent a receptor from interacting with its ligand, all of which can lead to cell death. Multiple antibodies are approved to treat cancer, including Alemtuzumab, Ipilimumab, Nivolumab, Ofatumumab, and Rituximab.Cellular therapies, also known as cancer vaccines, usually involve the removal of immune cells from the blood or from a tumor. Immune cells specific for the tumor are activated, cultured and returned to the patient where the immune cells attack the cancer. Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells. The only cell-based therapy approved in the US is Dendreon's Provenge, for the treatment of prostate cancer.Interleukin-2 and interferon-α are examples of cytokines, proteins that regulate and coordinate the behaviour of the immune system. They have the ability to enhance anti-tumor activity and thus can be used as cancer treatments. Interferon-α is used in the treatment of hairy-cell leukaemia, AIDS-related Kaposi's sarcoma, follicular lymphoma, chronic myeloid leukaemia and malignant melanoma. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma.