• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
cells of the immune system
cells of the immune system

... The WBC of the immune system work together through a variety of complex interactions to defend the host. These interactions are essential and have evolved to rid the body of pathogens and other foreign substances. There are two sites at which pathogens may be located: 1. Extracellular sites 2. Intra ...
Immunology: Basic Principles of Adaptive Immunity and Immunizations
Immunology: Basic Principles of Adaptive Immunity and Immunizations

... status - a parent's recollection of the disease is considered a reliable measure of previous infection and therefore immunity.・ Children between 19 months and their 13th birthday who have not had chickenpox should be vaccinated with a single dose.・People 13 and older who have not had chickenpox shou ...
What is the role of class II MHC proteins on donor cells in graft
What is the role of class II MHC proteins on donor cells in graft

... A.they are proteins with variable and constant regions B.they contain carbohydrates C.they are only secreted by T-cells D.they can combine very specifically with antigen E.they are structurally organized in globular domains 37. Natural killer cells A.are B cells that can kill without complement. B.a ...
HIV and immunity
HIV and immunity

... A substance produced by a pathogen (e.g., protein, complex sugar) capable of producing an immune response ...
Mammalian Differentiated Cell Types, Part 2
Mammalian Differentiated Cell Types, Part 2

... Leucocytes (white blood cells) protect against infections. Blood contains about one leucocyte for every 100 red blood cells. Although leucocytes travel in the circulation, they can pass through the walls of blood vessels to do their work in the surrounding tissues. There are several different kinds, ...
File
File

... antibody molecule that will recognise a specific antigen surface molecule on a pathogen or a toxin. Antigen-antibody complexes may inactivate a pathogen or toxin or render it more susceptible to phagocytosis. In other cases the antigen-antibody complex stimulates a response which results in cell lys ...
Quiz 06-07_key
Quiz 06-07_key

... B. FALSE 6. The granulocytes important in the innate immune response are the neutrophils. (1 pt) A. TRUE B. FALSE 7. Macrophages are (2 pts) A. the professional phagocyte, first to arrive at the scene of an infection B. important in the process of inflammation C. may be activated by T cells to form ...
Cell cooperation in immune response
Cell cooperation in immune response

... APCs display peptide fragments of protein antigen on their surface MHC class II molecules to facilitate antigen recognition by T helper cells via the T cell surface receptors. This interaction initiate T cell activation, which is amplified by further interaction between other molecules known as cost ...
Tumor immunity
Tumor immunity

Immunosenescence and Its Aplications to Artificial Immune
Immunosenescence and Its Aplications to Artificial Immune

... activation of immune responses in aged animals. The Journal of Immunology 177 (2006) 8348-8355 13. Colonna-Romano, G., Bulati, M., Aquino, A., Vitello, S., Lio, D., Candore, G., Caruso, C.: B cell immunosenescence in the elderly and in centenarians. Rejuvenation Research 11 (2008) 433-439 Parnas, D. ...
Unraveling the Tissue Specific Antigen Presentation That Results in
Unraveling the Tissue Specific Antigen Presentation That Results in

... significant potential of adeno-associated virus (AAV) vectors as a therapeutic tool for in vivo gene transfer. Unfortunately, there has been only minimal success in translation of these results into clinical studies. Data obtained from the animal studies and recent human clinical trials suggests tha ...
cmFPA008, an Anti-Mouse CSF-1R Antibody, Combines with
cmFPA008, an Anti-Mouse CSF-1R Antibody, Combines with

Understanding the Immune System
Understanding the Immune System

... – T-Cells (Thymus derived) Natural Killer Cells (Innate Immunity)  CD4+ T-Cells (helper cells)  CD8+ T-Cells (cytotoxic cells) ...
Antibody Production and Use in Immunodetection
Antibody Production and Use in Immunodetection

... antibody molecules with slightly different amino acid sequences that can further tested to find the one with the most affinity for an antigen  The recombinant DNA can be engineered to encode a human antibody molecule with the binding portion of a mouse. This type of antibody is called “humanized” o ...
Unit 4 Seminar Cellular immunity Immunology Dr. Furr A quick
Unit 4 Seminar Cellular immunity Immunology Dr. Furr A quick

... How do the innate immune system and the acquired immune system work together to fight infectious agents? ...
Cells of the Immune System
Cells of the Immune System

mental stress workshop
mental stress workshop

... engulf and initiate inflammatory response by releasing cytokines and chemokines to bring PMN’s to the site. Also initiate adaptive immune response a) Super-killer macrophages ...
Chapter 40-2
Chapter 40-2

... that breaks down the cell walls of bacteria  Oil & sweat glands produce an acidic environment on the skin that kills many bacteria  Mucus in mouth & nose help trap pathogens  Stomach acids & digestive enzymes destroy many pathogens that get in your stomach ...
Document
Document

... • Are caused by IgG and IgM antibodies directed against cell surface, extracellular matrix and intracellular antigens. The latter are usually non-pathogenic but diagnostically useful • Transfusion reactions to erythrocytes are due to antibodies to blood group antigens • The antibodies damage cells a ...
PowerPoint Presentation - I. Introduction to class
PowerPoint Presentation - I. Introduction to class

... plasma, lymph, mucus, etc.) and the surface of B cells.  Defense against bacteria, bacterial toxins, and viruses that circulate freely in body fluids, before they enter ...
antigen
antigen

... • They recognize a portion of the donor cell’s MHC complex as self, view a portion as foreign • Treat the combination as an antigenMHC complex and attack donor cells ...
Document
Document

... - An allergy is an unusually high sensitivity to some substance. If this substance causes an allergic reaction, it is known as an ...
The Immune System - SD43 Teacher Sites
The Immune System - SD43 Teacher Sites

... - An allergy is an unusually high sensitivity to some substance. If this substance causes an allergic reaction, it is known as an ...
Serology Notes Blood Volume and Composition Hemocytoblasts
Serology Notes Blood Volume and Composition Hemocytoblasts

... Serology – the study of bodily fluids, may include antibody-antigen reactions A. Presumptive detection of drugs using antibodies 1. inject animal with a specific drug-protein (antigen) complex of interest 2. animal creates antibodies which are removed from the serum ...
An Alternative Diagnostic Method Using Microneedles For Sampling
An Alternative Diagnostic Method Using Microneedles For Sampling

... Current protocols for immune system monitoring involve the collection of cells from blood or cerebrospinal fluid. However, since major populations of immune cells reside within tissues, these invasively-obtained body fluid samples are, at best, indirect indicators of the status of the immune system. ...
< 1 ... 455 456 457 458 459 460 461 462 463 ... 523 >

Cancer immunotherapy



Cancer immunotherapy (immuno-oncology) is the use of the immune system to treat cancer. Immunotherapies fall into three main groups: cellular, antibody and cytokine. They exploit the fact that cancer cells often have subtly different molecules on their surface that can be detected by the immune system. These molecules, known as cancer antigens, are most commonly proteins, but also include molecules such as carbohydrates. Immunotherapy is used to provoke the immune system into attacking the tumor cells by using these antigens as targets.Antibody therapies are the most successful immunotherapy, treating a wide range of cancers. Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. In normal physiology the immune system uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to cancer antigens are used to treat cancer. Cell surface receptors are common targets for antibody therapies and include the CD20, CD274, and CD279. Once bound to a cancer antigen, antibodies can induce antibody-dependent cell-mediated cytotoxicity, activate the complement system, or prevent a receptor from interacting with its ligand, all of which can lead to cell death. Multiple antibodies are approved to treat cancer, including Alemtuzumab, Ipilimumab, Nivolumab, Ofatumumab, and Rituximab.Cellular therapies, also known as cancer vaccines, usually involve the removal of immune cells from the blood or from a tumor. Immune cells specific for the tumor are activated, cultured and returned to the patient where the immune cells attack the cancer. Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells. The only cell-based therapy approved in the US is Dendreon's Provenge, for the treatment of prostate cancer.Interleukin-2 and interferon-α are examples of cytokines, proteins that regulate and coordinate the behaviour of the immune system. They have the ability to enhance anti-tumor activity and thus can be used as cancer treatments. Interferon-α is used in the treatment of hairy-cell leukaemia, AIDS-related Kaposi's sarcoma, follicular lymphoma, chronic myeloid leukaemia and malignant melanoma. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report