• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
File
File

IgM Humoral immune response to thymus
IgM Humoral immune response to thymus

... neutralize and eliminate extracellular pathogens and their toxins Cell mediators of humoral immunity are B lymphocites ...
Immunology – Immune System Overview
Immunology – Immune System Overview

... body’s normal metabolism. There are a number of different pathogenic organisms which cause disease and thus disturb the body’s normal function. These are as follows:  Fungi  Bacteria  Parasites  Protozoa  Helminths  Cancer: body cells become cancerous and uncontrolled cell growth and cell divi ...
Innate immune responses to cationic antimicrobial peptides in the lung
Innate immune responses to cationic antimicrobial peptides in the lung

... least partially due to pre-existing inflammation. In addition there is no question that inflammatory response plays an important role in late stage CF lung disease. Cationic antimicrobial peptides have been proposed as a therapeutic option for the treatment of CF. The ability of peptides to kill P. ...
1. dia - immunology.unideb.hu
1. dia - immunology.unideb.hu

... • Antigen (Ag) - any substance, which is recognized by the mature immune system of a given organism – antigenicity - specific reactivity with cells or molecules of the immune system – immunogenicity - capability to elicit an immune response ...
The Selective p110 Inhibitor IPI-3063 Potently Suppresses B Cell
The Selective p110 Inhibitor IPI-3063 Potently Suppresses B Cell

... The phosphoinositide-3-kinase (PI3K) signaling pathway is a crucial pathway that is involved in many cellular processes such as differentiation, proliferation and cell survival. The p110δ catalytic isoform of PI3K is critical for these cellular processes in B lymphocytes. Elevated PI3K signaling, ho ...
File - PBL Group 14
File - PBL Group 14

... in aqueous environments yet also enter lipid-rich membranes. Once in a target microbial membrane, the peptide kills target cells through diverse mechanisms. Cathelicidins (found in lysosomes) and defensins are major groups of epidermal AMPs. In addition to important antimicrobial properties, growing ...
Phenotypic Characterization of Human cd T
Phenotypic Characterization of Human cd T

... human cd T-cells in cryopreserved peripheral blood mononuclear cells (PBMC) from healthy individuals (Tables 1 and 2). As the majority of pan-cd T-cell antibodies available commercially proved to be inappropriate for detecting all cd T-cell populations in combination with other markers, this panel p ...
Immunology (B)
Immunology (B)

... +T cells develop. Interaction between matrix and thymus cells plays an important role in T cell development and maturation. 2.Epitope: Antigen molecules each have a set of antigenic determinants, also called epitopes. Epitopes are molecular shapes recognized by antibodies of the adaptive immune syst ...
Sistem Keta - IGP355 – PATOFISIOLOGI PENYAKIT II
Sistem Keta - IGP355 – PATOFISIOLOGI PENYAKIT II

... Auotimmune diseases can result if lymphocytes are not properly "educated," those lymphocytes that can attack self-antigens are not removed in the thymus or bone marrow during development. They can also occur if new self-antigens appear later in the life. The immune system can unfortunately see these ...
cytotoxic T cell
cytotoxic T cell

Možnosti imunomodulační léčby
Možnosti imunomodulační léčby

... Clinical use of IVIg effect proven by RCT immune trombocytopenia Guillain-Barré syndrome chronic demyelinizating neuropathy Kawasaki disease Dermatomyositis Lambert-Eaton myastenic syndrome Multifocal neuropathy effect not proven by RCT viral induced malaise rheumatoid arthritis juvenile rheumatoid ...
Plants and Pollinators
Plants and Pollinators

... • Virgin B cell becomes antigen-presenting B cell • Helper T cell binds to antigen-MHC complex on the B cell • Interleukins stimulate B cell division and differentiation • Effector cells secrete antibodies ...
immune responses
immune responses

...  Plasma: cell-free liquid with clotting factors in solution (must use an anticoagulant) ...
List of accepted posters - Be There Or Die? The Role Of The
List of accepted posters - Be There Or Die? The Role Of The

... Vertically acquired HIV infection causes signifcant changes to the B cell compartment and the quality of immunity to natural and vaccine antigens. It may be protected with early viral control. ...
How our body fights to keep us healthy
How our body fights to keep us healthy

... • The virus is too weak to make us ill but now we have antibodies ready so if the original measles virus gets into our body we already have the weapon to attack it straight away and so we do not get ill or only feel mildly ...
Chapter 43 - The Immune System
Chapter 43 - The Immune System

... nonheritable defense mechanisms against pathogens  The mammalian immune system includes two types of specific responses: cell mediated and humoral  In the cell-mediated response, cytotoxic T cells, a type of lymphocytic white blood cell, “target” intracellular pathogens when antigens are displayed ...
Lymphatic System Guided Notes
Lymphatic System Guided Notes

... Occurs when white blood cells release chemicals that reset the body’s thermostat How does it protect the body?  ______________________________________________ by causing the liver & spleen to take up nutrients  _______________________________________________ to speed the healing process ...
Protective Immune Responses during Epstein Barr Virus (EBV
Protective Immune Responses during Epstein Barr Virus (EBV

4 4 2nd line of defense and specific defenses
4 4 2nd line of defense and specific defenses

... (small part of a pathogen with cells shape that fits an antibody) Antigen-antibody must fit like a lock and key ...
LU Jinhua
LU Jinhua

... Zhang H, Tay PN, Cao W, Li W and Lu J. (2002) Integrin-nucleated toll-like receptor (TLR) dimerization reveals subcellular targeting of TLRs and distinct mechanisms of TLR4 activation and signaling. FEBS Lett. 532, 171-176 Cao W, Bobryshev YV, Lord RSA, Oakley REI, Lee SH and Lu J. (2003) Dendritic ...
Chapter 43:The Body`s Defenses - Volunteer State Community
Chapter 43:The Body`s Defenses - Volunteer State Community

... • These are nonspecific because they do not distinguish among specific pathogens. ...
the scientific sessions
the scientific sessions

... ...
Immunology Terms Phagocytosis- method of engulfing and
Immunology Terms Phagocytosis- method of engulfing and

... MHC class I- cell marker that presents viral infections to immune system MHC class II- cell marker that presents bacterial infections to immune system Anigen Presenting cell- any cell capable of connecting with a T cell that can lead to activation of the adaptive immune response Epitope- the specifi ...
The Blister Battle - MSOE Center for BioMolecular Modeling
The Blister Battle - MSOE Center for BioMolecular Modeling

... Along with angiogenin’s promising involvement in treating  Bullous Pemphigoid, the protein might also prove useful in  treating a variety of human cancers and angiogenesis‐ dependent diseases, such as endometriosis and diabetes.  Angiogenin, primarily circulating in the body’s  bloodstream, is vital ...
< 1 ... 454 455 456 457 458 459 460 461 462 ... 523 >

Cancer immunotherapy



Cancer immunotherapy (immuno-oncology) is the use of the immune system to treat cancer. Immunotherapies fall into three main groups: cellular, antibody and cytokine. They exploit the fact that cancer cells often have subtly different molecules on their surface that can be detected by the immune system. These molecules, known as cancer antigens, are most commonly proteins, but also include molecules such as carbohydrates. Immunotherapy is used to provoke the immune system into attacking the tumor cells by using these antigens as targets.Antibody therapies are the most successful immunotherapy, treating a wide range of cancers. Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. In normal physiology the immune system uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to cancer antigens are used to treat cancer. Cell surface receptors are common targets for antibody therapies and include the CD20, CD274, and CD279. Once bound to a cancer antigen, antibodies can induce antibody-dependent cell-mediated cytotoxicity, activate the complement system, or prevent a receptor from interacting with its ligand, all of which can lead to cell death. Multiple antibodies are approved to treat cancer, including Alemtuzumab, Ipilimumab, Nivolumab, Ofatumumab, and Rituximab.Cellular therapies, also known as cancer vaccines, usually involve the removal of immune cells from the blood or from a tumor. Immune cells specific for the tumor are activated, cultured and returned to the patient where the immune cells attack the cancer. Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells. The only cell-based therapy approved in the US is Dendreon's Provenge, for the treatment of prostate cancer.Interleukin-2 and interferon-α are examples of cytokines, proteins that regulate and coordinate the behaviour of the immune system. They have the ability to enhance anti-tumor activity and thus can be used as cancer treatments. Interferon-α is used in the treatment of hairy-cell leukaemia, AIDS-related Kaposi's sarcoma, follicular lymphoma, chronic myeloid leukaemia and malignant melanoma. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report