• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Chapter 21 PowerPoint - Hillsborough Community College
Chapter 21 PowerPoint - Hillsborough Community College

... • Substances that can mobilize the adaptive defenses and provoke an immune response ...
Document
Document

... As a biochemist and molecular biologist by training, Dr. Verma obtained a Ph.D in Life Sciences from India (University of Indore). During her post doctoral training as a Project Scientist at the National Institute of Immunology, New Delhi, India worldwide known for applied and translational immunolo ...
S. aureus infection
S. aureus infection

... anatomic structure and function ...
Objectives/Competencies - Springfield Technical Community College
Objectives/Competencies - Springfield Technical Community College

... 9. Students will identify the types of cells involved in the Processes of Adaptive Immunity. 10. Students will describe the MHC – Major Histocompatibility Complex and its function. ...
1. dia
1. dia

... • Upstream of C regions are repetitive regions of DNA called switch regions. (The exception is the Cd region that has no switch region). • The Sm consists of 150 repeats of [(GAGCT)n(GGGGGT)] where n is between 3 and 7. • Switching is mechanistically similar in many ways to V(D)J recombination, but ...
A Possible Link Between Autoimmunity and Cancer
A Possible Link Between Autoimmunity and Cancer

... immune response in cancer, immature pDCs are activated by Toll-like receptors, which lead to B- and T-cell immune responses in autoimmune disease (Lang et al., 2005). The immunological tolerance is produced by tumour-derived soluble factors (TDSFs) and immature dendritic cells (iDCs), which inhibit ...
Lymphatic System
Lymphatic System

... Immunity that develops after a person has had a disease ...
Innate Immunity Underlies Symbiotic Relationships
Innate Immunity Underlies Symbiotic Relationships

... restricting penetration of bacteria into internal environment of the body; surveillance and control for inhabitant microbes; creation and continuous maintenance of conditions hampering development of inflammation; preservation and transfer of beneficial microbes to progeny. The abovementioned tasks ...
Document
Document

... Dendritic cells (DCs) (see footnote) can be found in three types of location within the body. They are present as ‘immature’ cells in peripheral tissues, especially tissues that are exposed to the external environment, including the skin, lungs and intestine. They are also present in lymphoid tissue ...
Aviremia 10 Years Postdiscontinuation of Antiretroviral Therapy
Aviremia 10 Years Postdiscontinuation of Antiretroviral Therapy

Part 1 MRCSI (Ophth) - Royal College of Surgeons in Ireland
Part 1 MRCSI (Ophth) - Royal College of Surgeons in Ireland

... The pass mark is determined in advance of each examination by the Examinations Committee using the Angoff method of standard setting. ...
Merck KGaA, Darmstadt, Germany, and Pfizer
Merck KGaA, Darmstadt, Germany, and Pfizer

... 'platinum-resistant' disease if the disease worsens within 6 months of completing platinum-based Page 2 of 4 ...
Blood
Blood

... and lymphoid stem cells. Myeloid stem cells turn into red blood cells, platelets, monocytes, neutrophils, eosinophils, and basophils after developing in the red bone marrow. Lymphoid stem cells start developing in the red bone marrow but finish developing in lymphatic tissues, and give rise to lymph ...
Part 1 MRCSI (Ophth) regulations and guidance notes
Part 1 MRCSI (Ophth) regulations and guidance notes

... The pass mark is determined in advance of each examination by the Examinations Committee using the Angoff method of standard setting. ...
Mature Dendritic Cells Derived from Human Monocytes
Mature Dendritic Cells Derived from Human Monocytes

... the yield of isolated cells (13), most experimental and clinical studies currently rely on the in vitro development of DC-like cells from CD34⫹ progenitor cells or blood monocytes (14 –16). Commonly, monocytes are cultured for 5–7 days with GM-CSF and IL-4 to generate immature DCs that have to be ac ...
Profiling B and T cell immune responses to Mycobacterium tuberculosis co-infection of
Profiling B and T cell immune responses to Mycobacterium tuberculosis co-infection of

... countries [4-6]. Therefore, it is essential to profile the human co-infection of Mycobacterium tuberculosis (MTB) and hookworm. MTB is a facultative intracellular pathogen. The effective cell-mediated immune response to MTB infection, involving mainly the CD4+ and CD8+ T cell subsets, plays an essen ...
Granuloma cells in chronic inflammation express CD205 (DEC205
Granuloma cells in chronic inflammation express CD205 (DEC205

... granulomatous pleuritis (cause unidentified) and granulomatous inflammation of the lung associated with lung cancer (cause unidentified). In patients with non-malignant diseases, the sampling was performed to confirm the diagnosis, and no treatments had been performed on the patients. In patients wi ...
Immune responses to human papilloma viruses
Immune responses to human papilloma viruses

... T cell responses to E2 and, probably E6 are important at least in hrHPV infections. A non intervention follow up study of women with cytological evidence of low grade CIN, showed that HPV16 E2-specific T cell responses, as measured by specific IL-2 release in vitro, occurred frequently at the time o ...
Integrating Metabolism and Immunity
Integrating Metabolism and Immunity

HIV Pathogenesis 2000: Clinical implications
HIV Pathogenesis 2000: Clinical implications

... Host immune responses ...
B antigen
B antigen

... in their serum • However, the anti-A can be separated into different components: anti-A and anti-A1 • Anti-A1 only agglutinates the A1 antigen, not the A2 antigen • There is no anti-A2. ...
Responding to STD/HIV Increases and Viagra Use
Responding to STD/HIV Increases and Viagra Use

... Since antibodies are proteins too, they themselves are also antigens. Scientist developed an anti-HIV antibody antibody. So this new antibody sticks to the back of the first antibody. This second antibody has an enzyme is attached to it. When a reactive substrate is added to the mix, the enzyme will ...
Immune cellular regulation on autoantibody production in pemphigus
Immune cellular regulation on autoantibody production in pemphigus

... AND LOSS OF SELF-TOLERANCE IN B CELLS B cells serve as one of the major autoantibody-secreting cells in autoimmune diseases. Additionally, they may function as selfantigen-presenting cells. Furthermore, B cells may regulate the T-cell development and function in vivo through multiple mechanisms. In ...
fascia sop - entire-net
fascia sop - entire-net

... Small deviations from the reference values should be interpreted with caution. The variation between individuals is large. ...
Plasmodium
Plasmodium

... People with ovalocytosis have blood cell walls that are so rigid they can’t slip through capillaries. The rigid cell walls make it hard for the parasite to enter the cell and the cell’s rigidity appears to prevent the parasite pumping in phosphates and sulphates it n ...
< 1 ... 165 166 167 168 169 170 171 172 173 ... 523 >

Cancer immunotherapy



Cancer immunotherapy (immuno-oncology) is the use of the immune system to treat cancer. Immunotherapies fall into three main groups: cellular, antibody and cytokine. They exploit the fact that cancer cells often have subtly different molecules on their surface that can be detected by the immune system. These molecules, known as cancer antigens, are most commonly proteins, but also include molecules such as carbohydrates. Immunotherapy is used to provoke the immune system into attacking the tumor cells by using these antigens as targets.Antibody therapies are the most successful immunotherapy, treating a wide range of cancers. Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. In normal physiology the immune system uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to cancer antigens are used to treat cancer. Cell surface receptors are common targets for antibody therapies and include the CD20, CD274, and CD279. Once bound to a cancer antigen, antibodies can induce antibody-dependent cell-mediated cytotoxicity, activate the complement system, or prevent a receptor from interacting with its ligand, all of which can lead to cell death. Multiple antibodies are approved to treat cancer, including Alemtuzumab, Ipilimumab, Nivolumab, Ofatumumab, and Rituximab.Cellular therapies, also known as cancer vaccines, usually involve the removal of immune cells from the blood or from a tumor. Immune cells specific for the tumor are activated, cultured and returned to the patient where the immune cells attack the cancer. Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells. The only cell-based therapy approved in the US is Dendreon's Provenge, for the treatment of prostate cancer.Interleukin-2 and interferon-α are examples of cytokines, proteins that regulate and coordinate the behaviour of the immune system. They have the ability to enhance anti-tumor activity and thus can be used as cancer treatments. Interferon-α is used in the treatment of hairy-cell leukaemia, AIDS-related Kaposi's sarcoma, follicular lymphoma, chronic myeloid leukaemia and malignant melanoma. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report