9280 poster.indd
... What happens when a cell comes into contact with a surface? Cells that come into contact with a surface do so through an adsorbed layer of proteins. These proteins are present in the blood and adsorb on the surface within a matter of a few seconds. Biocompatibility is, at least in part, directed by ...
... What happens when a cell comes into contact with a surface? Cells that come into contact with a surface do so through an adsorbed layer of proteins. These proteins are present in the blood and adsorb on the surface within a matter of a few seconds. Biocompatibility is, at least in part, directed by ...
T-cell development in thymus
... positive selection, in the cortex. DP cells interact with self-antigens in the context of major histocompatabilty complex (MHC) class I or class II molecules. Those cells that engage antigen/MHC with an appropriate affinity survive, whereas those cells that interact with a weaker affinity die by apo ...
... positive selection, in the cortex. DP cells interact with self-antigens in the context of major histocompatabilty complex (MHC) class I or class II molecules. Those cells that engage antigen/MHC with an appropriate affinity survive, whereas those cells that interact with a weaker affinity die by apo ...
Immunty to inf 2 MT
... 1- Response to viral infection may cause tissue damage Ag-Ab complex deposition in kidney and blood >>> inflammatory response >>> T cell mediated damage >> killing of host cells 2- Virus may infect immune cells 3- Viral infection may induce autoimmunity due to antigenic mimicry ...
... 1- Response to viral infection may cause tissue damage Ag-Ab complex deposition in kidney and blood >>> inflammatory response >>> T cell mediated damage >> killing of host cells 2- Virus may infect immune cells 3- Viral infection may induce autoimmunity due to antigenic mimicry ...
innate immunity
... The specific immune response increases the protective mechanism of innate immunity by attacking only specific antigen that are compatible with itself. Memory: When B cells and T cells are activated some will become memory cells. Upon interaction with a previously encountered antigen, the appropria ...
... The specific immune response increases the protective mechanism of innate immunity by attacking only specific antigen that are compatible with itself. Memory: When B cells and T cells are activated some will become memory cells. Upon interaction with a previously encountered antigen, the appropria ...
Non Specific Immune Responses (Chapter 16) First Line of Defense:
... B. Alternative Activation: (does not involve antigen) Proteins B, D, F factors in blood bind to pathogen and activate C3 C. Lectin pathway: Macrophage that ingestions pathogens release chemical to stimulate liver to produce lectin (proteins that bind to carbohydrates). One type of lectin binds to ma ...
... B. Alternative Activation: (does not involve antigen) Proteins B, D, F factors in blood bind to pathogen and activate C3 C. Lectin pathway: Macrophage that ingestions pathogens release chemical to stimulate liver to produce lectin (proteins that bind to carbohydrates). One type of lectin binds to ma ...
cell - immunology.unideb.hu
... Antibodies are natural products that appear on the cell surface as receptors and selectively react with the antigen Lymphocyte receptors are variable and carry various antigen-recognizing receptors ‘Non-self’ antigens/pathogens encounter the existing lymphocyte pool (repertoire) Antigens select thei ...
... Antibodies are natural products that appear on the cell surface as receptors and selectively react with the antigen Lymphocyte receptors are variable and carry various antigen-recognizing receptors ‘Non-self’ antigens/pathogens encounter the existing lymphocyte pool (repertoire) Antigens select thei ...
NK receptors
... rearrangements to generate receptor diversity (unlike NK cells) - These subsets express limited receptor diversity, utilizing only a small number of receptor gene segments - Tend to found in specific locations in the body, usually sites that encounter exogenous antigens or pathogens ...
... rearrangements to generate receptor diversity (unlike NK cells) - These subsets express limited receptor diversity, utilizing only a small number of receptor gene segments - Tend to found in specific locations in the body, usually sites that encounter exogenous antigens or pathogens ...
Chapter 12
... they secrete molecules, known as cytokines, that activate B and T cells. Antibody-Mediated (Humoral) Immunity Humoral immunity is mediated by antibodies, products of B cells (with the aid of TH cells) in response to antigens. Each antibody is constructed from two heavy (H) and two light (L) protein ...
... they secrete molecules, known as cytokines, that activate B and T cells. Antibody-Mediated (Humoral) Immunity Humoral immunity is mediated by antibodies, products of B cells (with the aid of TH cells) in response to antigens. Each antibody is constructed from two heavy (H) and two light (L) protein ...
Review for Human Body Test #3 Endocrine, Excretory, Immune
... 3. ____________________ Calcium (this gland controls calcium absorption in your body) 4. ____________________ Day and Night (this gland helps to set your circadian, or day and night rhythm) 5. ____________________ Female hormones (these glands make estrogen and progesterone in females) 6. __________ ...
... 3. ____________________ Calcium (this gland controls calcium absorption in your body) 4. ____________________ Day and Night (this gland helps to set your circadian, or day and night rhythm) 5. ____________________ Female hormones (these glands make estrogen and progesterone in females) 6. __________ ...
4 4 2nd line of defense and specific defenses
... - white blood 1. B cells recognize antigens (small part of a pathogen with cells shape that fits an antibody) Antigen-antibody must fit like a lock and key ...
... - white blood 1. B cells recognize antigens (small part of a pathogen with cells shape that fits an antibody) Antigen-antibody must fit like a lock and key ...
Lac 2
... ANTIGEN-PRESENTING CELLS Activation of both the humoral and cell-mediated branches of the immune system requires cytokines produced by TH cells. It is essential that activation of TH cells themselves be carefully regulated, because an inappropriate T-cell response to self-components can have fatal a ...
... ANTIGEN-PRESENTING CELLS Activation of both the humoral and cell-mediated branches of the immune system requires cytokines produced by TH cells. It is essential that activation of TH cells themselves be carefully regulated, because an inappropriate T-cell response to self-components can have fatal a ...
Name - Medical Mastermind Community
... 13. Which statement BEST describes T helper 3 type (Th3) lymphocytes: A. They primarily secrete IL-2 and Interferon-gamma upon activation B. They give help to B cells to produce IgG2a C, They primarily secrete TGF-beta upon activation D. They suppress T helper I cells, but not T helper 2 cells E. Th ...
... 13. Which statement BEST describes T helper 3 type (Th3) lymphocytes: A. They primarily secrete IL-2 and Interferon-gamma upon activation B. They give help to B cells to produce IgG2a C, They primarily secrete TGF-beta upon activation D. They suppress T helper I cells, but not T helper 2 cells E. Th ...
Lymphatic System Part 2
... Antibodies of each class have slightly different roles Five major immunoglobulin classes (MADGE) IgM—can fix complement IgA—found mainly in mucus IgD—important in activation of B cell IgG—can cross the placental barrier and fix complement IgE—involved in allergies ...
... Antibodies of each class have slightly different roles Five major immunoglobulin classes (MADGE) IgM—can fix complement IgA—found mainly in mucus IgD—important in activation of B cell IgG—can cross the placental barrier and fix complement IgE—involved in allergies ...
341-541 - McDermott.doc
... Students needing extra time to complete in class exams must make arrangements with instructor prior to examination period. Students unable to attend in class examinations due to illness or emergency must notify instructor or departmental office (424-1102) prior to the exam. Exams 1 and 2 will be giv ...
... Students needing extra time to complete in class exams must make arrangements with instructor prior to examination period. Students unable to attend in class examinations due to illness or emergency must notify instructor or departmental office (424-1102) prior to the exam. Exams 1 and 2 will be giv ...
Lymphatic System
... activates complement system IgA- in exocrine gland secretions IgM- in plasma; activates complement system IgD- found on surfaces of B cells; activates B cells IgE- in exocrine gland secretions; associated with allergic reaction ...
... activates complement system IgA- in exocrine gland secretions IgM- in plasma; activates complement system IgD- found on surfaces of B cells; activates B cells IgE- in exocrine gland secretions; associated with allergic reaction ...
10 PhD positions in the EN‐ACTI2NG H2020‐MSCA‐ITN
... are most interested in, listing the project numbers and titles in order of preference. These documents should be sent in a single pdf file to the consortium’s email address ([email protected]) mentioning in the subject line: EN‐ACTI2NG application and the numbers of the 3 projects in preferred o ...
... are most interested in, listing the project numbers and titles in order of preference. These documents should be sent in a single pdf file to the consortium’s email address ([email protected]) mentioning in the subject line: EN‐ACTI2NG application and the numbers of the 3 projects in preferred o ...
Innate vs Adaptive Immunity
... PASSIVE Antibodies are Antibodies or lymphocytes are passed to foetus ...
... PASSIVE Antibodies are Antibodies or lymphocytes are passed to foetus ...
Gene Therapy Gene Therapy
... to foreign agents Inhibit viral replication within cells Activate natural killer T cells and macrophages Increase antigen presentation and resistance of host cell to viral infection Used to treat cancer because cells do not proliferate as easily Has unfortunate short serum half-life Use gene therapy ...
... to foreign agents Inhibit viral replication within cells Activate natural killer T cells and macrophages Increase antigen presentation and resistance of host cell to viral infection Used to treat cancer because cells do not proliferate as easily Has unfortunate short serum half-life Use gene therapy ...
Immunology Exam
... result in the production of memory cells that recognize the pathogenic antigen take about two weeks after treatment to become effective involve recognition of a pathogenic antigen by antibodies can result in a patient getting serum sickness are principally innate responses ...
... result in the production of memory cells that recognize the pathogenic antigen take about two weeks after treatment to become effective involve recognition of a pathogenic antigen by antibodies can result in a patient getting serum sickness are principally innate responses ...
Adaptive immune system
The adaptive immune system, also known as the acquired immune or, more rarely, as the specific immune system, is a subsystem of the overall immune system that is composed of highly specialized, systemic cells and processes that eliminate or prevent pathogen growth. The adaptive immune system is one of the two main immunity strategies found in vertebrates (the other being the innate immune system). Adaptive immunity creates immunological memory after an initial response to a specific pathogen, leads to an enhanced response to subsequent encounters with that pathogen. This process of acquired immunity is the basis of vaccination. Like the innate system, the adaptive system includes both humoral immunity components and cell-mediated immunity components.Unlike the innate immune system, the adaptive immune system is highly specific to a specific pathogen. Adaptive immunity can also provide long-lasting protection: for example; someone who recovers from measles is now protected against measles for their lifetime but in other cases it does not provide lifetime protection: for example; chickenpox. The adaptive system response destroys invading pathogens and any toxic molecules they produce. Sometimes the adaptive system is unable to distinguish foreign molecules, the effects of this may be hayfever, asthma or any other allergies. Antigens are any substances that elicit the adaptive immune response. The cells that carry out the adaptive immune response are white blood cells known as lymphocytes. Two main broad classes—antibody responses and cell mediated immune response—are also carried by two different lymphocytes (B cells and T cells). In antibody responses, B cells are activated to secrete antibodies, which are proteins also known as immunoglobulins. Antibodies travel through the bloodstream and bind to the foreign antigen causing it to inactivate, which does not allow the antigen to bind to the host.In acquired immunity, pathogen-specific receptors are ""acquired"" during the lifetime of the organism (whereas in innate immunity pathogen-specific receptors are already encoded in the germline). The acquired response is called ""adaptive"" because it prepares the body's immune system for future challenges (though it can actually also be maladaptive when it results in autoimmunity).The system is highly adaptable because of somatic hypermutation (a process of accelerated somatic mutations), and V(D)J recombination (an irreversible genetic recombination of antigen receptor gene segments). This mechanism allows a small number of genes to generate a vast number of different antigen receptors, which are then uniquely expressed on each individual lymphocyte. Because the gene rearrangement leads to an irreversible change in the DNA of each cell, all progeny (offspring) of that cell inherit genes that encode the same receptor specificity, including the memory B cells and memory T cells that are the keys to long-lived specific immunity.A theoretical framework explaining the workings of the acquired immune system is provided by immune network theory. This theory, which builds on established concepts of clonal selection, is being applied in the search for an HIV vaccine.