ANA – Antinuclear Antibodies
... Interpretation: No clinically significant antinuclear antibody is detected by IFA. A negative result suggests an absence of connective tissue disease. False negatives may occur, especially in scleroderma, polymyositis/dermatomyositis, or inactive systemic lupus erythematosus. False positive ANA EI ...
... Interpretation: No clinically significant antinuclear antibody is detected by IFA. A negative result suggests an absence of connective tissue disease. False negatives may occur, especially in scleroderma, polymyositis/dermatomyositis, or inactive systemic lupus erythematosus. False positive ANA EI ...
the cd40 receptor - Immunotechnology
... (Banchereau et al., 2000). Alongside with the increasing understanding of the immune system there have been ongoing efforts to explore this knowledge to develop novel techniques and more efficient therapies. Köhler and Milstein’s development of the monoclonal antibody technology provided the researc ...
... (Banchereau et al., 2000). Alongside with the increasing understanding of the immune system there have been ongoing efforts to explore this knowledge to develop novel techniques and more efficient therapies. Köhler and Milstein’s development of the monoclonal antibody technology provided the researc ...
Evasion mechanisms of parasites - Biblioteca Virtual de la Real
... safe place for parasite growth, whereas in others they form part of the defence systems against infection. The strategies of parasitary evasion can be directed to inhibit apoptosis, or contrarily, to stimulate biological processes. It has been pro ved that infection ...
... safe place for parasite growth, whereas in others they form part of the defence systems against infection. The strategies of parasitary evasion can be directed to inhibit apoptosis, or contrarily, to stimulate biological processes. It has been pro ved that infection ...
WHITE BLOOD CELLS Formation Function ~ TEST YOURSELF
... either the blue alkaline stain or the red acid stain, so they are said to be neutral. This means they are difficult to see on a stained smear; so identification of neutrophils is commonly based on nuclear morphology, rather than granule staining ...
... either the blue alkaline stain or the red acid stain, so they are said to be neutral. This means they are difficult to see on a stained smear; so identification of neutrophils is commonly based on nuclear morphology, rather than granule staining ...
vaccines
... plasmid-encoded agonist of innate immune receptors to activate a large variety of molecules capable of promoting adaptive immunity, unlike many other approaches which use single cytokines or chemokines [3]. A major benefit of this system is that it works without physically linking the antigen to fla ...
... plasmid-encoded agonist of innate immune receptors to activate a large variety of molecules capable of promoting adaptive immunity, unlike many other approaches which use single cytokines or chemokines [3]. A major benefit of this system is that it works without physically linking the antigen to fla ...
Antigen-non-specific regulation centered on CD25+Foxp3+
... The primary aim of the immune system is to clear invading pathogens; however, excessive responses result in self-damage. Activation-induced cell death might be an intracellular mechanism to control excessive immune responses, but this negative feedback may be unable to detect an excessive response t ...
... The primary aim of the immune system is to clear invading pathogens; however, excessive responses result in self-damage. Activation-induced cell death might be an intracellular mechanism to control excessive immune responses, but this negative feedback may be unable to detect an excessive response t ...
Lecture Title: INTRODUCTION TO MEDICAL MICROBIOLOGY ( 1
... Lymphocyte Circulation Recognition of antigen by lymphocytes subpopulation 2 mechanisms to maximize the efficiency of the specific arm ...
... Lymphocyte Circulation Recognition of antigen by lymphocytes subpopulation 2 mechanisms to maximize the efficiency of the specific arm ...
Platelet-derived CD154 enables T-cell priming and
... infections, and play a role in modulating production of inflammatory cytokines in response to bacterial infections.15-17 Because of their ubiquitous presence in the circulation, platelets are the first cell type to specifically and intentionally accumulate at sites of injury where they are activated ...
... infections, and play a role in modulating production of inflammatory cytokines in response to bacterial infections.15-17 Because of their ubiquitous presence in the circulation, platelets are the first cell type to specifically and intentionally accumulate at sites of injury where they are activated ...
chapter 20-the lymphatic system
... are located in the cortex. The thymus gland does not contain B cells. D. Tonsils-are considered to be the simplest of all the lymphoid organs. 1. These form a ring around the pharynx and they are named according to location. 2. Types of Tonsils: a. Palatine Tonsils-paired, located on either side at ...
... are located in the cortex. The thymus gland does not contain B cells. D. Tonsils-are considered to be the simplest of all the lymphoid organs. 1. These form a ring around the pharynx and they are named according to location. 2. Types of Tonsils: a. Palatine Tonsils-paired, located on either side at ...
Mantovani A et al
... thyroid carcinoma and is a necessary and sufficient event for this cancer to develop. In an appropriate cellular context, which is provided by freshly isolated human thyrocytes, the activation of RET induces a transcriptional program that is similar to that which occurs during inflammation8 (Fig. 2) ...
... thyroid carcinoma and is a necessary and sufficient event for this cancer to develop. In an appropriate cellular context, which is provided by freshly isolated human thyrocytes, the activation of RET induces a transcriptional program that is similar to that which occurs during inflammation8 (Fig. 2) ...
Toll-like receptors in innate immunity
... predicted to recognize a nucleic acid-like structure of the virus. This prediction has recently been shown to be true from the finding that TLR7 and human TLR8 recognize guanosineor uridine-rich single-stranded RNA (ssRNA) from viruses such as human immunodeficiency virus, vesicular stomatitis virus ...
... predicted to recognize a nucleic acid-like structure of the virus. This prediction has recently been shown to be true from the finding that TLR7 and human TLR8 recognize guanosineor uridine-rich single-stranded RNA (ssRNA) from viruses such as human immunodeficiency virus, vesicular stomatitis virus ...
Document
... nanoparticles. Hydrophobic or amphipathic antigens can be incorporated into this complex. They are versatile and flexible delivery systems with increased efficiency of antigen presentation to B cells and uptake by the APC. vaccines are potent inducer of both humoral and cellular (CD4+ and CD8+ T-cel ...
... nanoparticles. Hydrophobic or amphipathic antigens can be incorporated into this complex. They are versatile and flexible delivery systems with increased efficiency of antigen presentation to B cells and uptake by the APC. vaccines are potent inducer of both humoral and cellular (CD4+ and CD8+ T-cel ...
Distribution and expression profiles of dendritic cell subpopulations
... being the predominant form. Dendritic cells (DCs) are a heterogeneous population of antigen-presenting cells that play a crucial role in the regulation of the immune response and immunological tolerance. The aim of this study was to investigate the expression and characteristic of different DC subse ...
... being the predominant form. Dendritic cells (DCs) are a heterogeneous population of antigen-presenting cells that play a crucial role in the regulation of the immune response and immunological tolerance. The aim of this study was to investigate the expression and characteristic of different DC subse ...
Mesenchymal stem cells in immunoregulation
... In humans and primates, CD81 veto cells are termed graftfacilitating cells and trigger the accumulation of TGF-b1 mRNA and protein, causing the deletion of the responding T cells.33,34 Studies suggest that TGF-b1 play a role in the MSC-induced suppression of CD81 T-cell proliferation.28,35 Therefore ...
... In humans and primates, CD81 veto cells are termed graftfacilitating cells and trigger the accumulation of TGF-b1 mRNA and protein, causing the deletion of the responding T cells.33,34 Studies suggest that TGF-b1 play a role in the MSC-induced suppression of CD81 T-cell proliferation.28,35 Therefore ...
The molecular mechanisms of TLR
... TLR7-MyD88 signaling axis mainly activates JunB and CEBPβ, whereas TLR3-TRIF pathway mainly activates IRF1. JunB, CEBPβ and IRF1 are all required for cytokine expression, and simultaneous activation of both TLR7-MyD88 and TLR3-TRIF pathways synchronize and sustain the activation of these three core ...
... TLR7-MyD88 signaling axis mainly activates JunB and CEBPβ, whereas TLR3-TRIF pathway mainly activates IRF1. JunB, CEBPβ and IRF1 are all required for cytokine expression, and simultaneous activation of both TLR7-MyD88 and TLR3-TRIF pathways synchronize and sustain the activation of these three core ...
1 Elevated IL-17 produced byTH17 cells promotes myeloma cell
... Intra-cellular IL-17 producing TH17 cell-analysis by flow cytometry: To evaluate baseline frequency of TH17 cells, PBMC and BMMC Isolated from healthy donors and myeloma patients were stimulated with PMA and ionomycin for six hours in the presence of Golgi stop (eBioscience, San Diego, CA) as descri ...
... Intra-cellular IL-17 producing TH17 cell-analysis by flow cytometry: To evaluate baseline frequency of TH17 cells, PBMC and BMMC Isolated from healthy donors and myeloma patients were stimulated with PMA and ionomycin for six hours in the presence of Golgi stop (eBioscience, San Diego, CA) as descri ...
Immunology for physicists - Laboratoire de Physique Statistique
... Lymphocytes are subdivided into two major classes: B cells and T cells. B lymphocytes secrete antibodies, one of the major protective molecules in our bodies. T cells function mainly by interacting with other cells and have been subdivided into helper T cells and cytotoxic T cells. Helper T cells, w ...
... Lymphocytes are subdivided into two major classes: B cells and T cells. B lymphocytes secrete antibodies, one of the major protective molecules in our bodies. T cells function mainly by interacting with other cells and have been subdivided into helper T cells and cytotoxic T cells. Helper T cells, w ...
CARMA1 Is Critical for the Development of Allergic Airway
... Copyright © 2006 by The American Association of Immunologists, Inc. ...
... Copyright © 2006 by The American Association of Immunologists, Inc. ...
Hypertensive anterior uveitis
... – Quantitative CMV-DNA PCR testing was performed using an AccuPower CMV Quantitative PCR Kit (Bioneer, Daejun, Republic of Korea). – For HSV PCR, the HSV 1/2 PCR Kit (Bio-Core, Seoul, Republic of Korea) was used. ...
... – Quantitative CMV-DNA PCR testing was performed using an AccuPower CMV Quantitative PCR Kit (Bioneer, Daejun, Republic of Korea). – For HSV PCR, the HSV 1/2 PCR Kit (Bio-Core, Seoul, Republic of Korea) was used. ...
Adenosine triphosphate acts as a paracrine signaling molecule to
... as a paracrine messenger involved in intracellular calcium mobilization activated by purinergic receptors (Osipchuk & Cahalan, 1992; Zsembery et al, 2003; Yegutkin, 2008). Thus, ATP-induced intercellular spreading of calcium signals—the so called calcium waves—has been observed in many cell types su ...
... as a paracrine messenger involved in intracellular calcium mobilization activated by purinergic receptors (Osipchuk & Cahalan, 1992; Zsembery et al, 2003; Yegutkin, 2008). Thus, ATP-induced intercellular spreading of calcium signals—the so called calcium waves—has been observed in many cell types su ...
Influence of congenital human cytomegalovirus infection and the
... [8–10]. Though most infected newborns are asymptomatic, ∼10% display a variety of clinical disorders [8, 11] potentially leading to important sequelae such as mental retardation and deafness. The type of maternal infection (i.e., primary versus reactivation/reinfection) conditions the risk of congen ...
... [8–10]. Though most infected newborns are asymptomatic, ∼10% display a variety of clinical disorders [8, 11] potentially leading to important sequelae such as mental retardation and deafness. The type of maternal infection (i.e., primary versus reactivation/reinfection) conditions the risk of congen ...
Challenges and strategies: The immune responses in gene therapy
... derived from viral particles, viral genes, and CpG DNA in plasmid. These potential immunostimulants may play important roles in inducing the host immune responses when foreign genes are transferred into the targeted tissues.1 Generally, viral vectors containing the genes of interest are packaged int ...
... derived from viral particles, viral genes, and CpG DNA in plasmid. These potential immunostimulants may play important roles in inducing the host immune responses when foreign genes are transferred into the targeted tissues.1 Generally, viral vectors containing the genes of interest are packaged int ...