Drug-Induced Hematologic Disorders
... antineoplastic agents exemplify the dose-dependent mechanism for the development of aplastic anemia. Many of these agents have the ability to suppress one or more cell lines in a reversible manner. The degree of suppression and the cell line involved depend on the nature of the particular drug and i ...
... antineoplastic agents exemplify the dose-dependent mechanism for the development of aplastic anemia. Many of these agents have the ability to suppress one or more cell lines in a reversible manner. The degree of suppression and the cell line involved depend on the nature of the particular drug and i ...
ImmunoJeopardy Introduction
... • Virus found chiefly in Africa which usually results in a swift death ...
... • Virus found chiefly in Africa which usually results in a swift death ...
Elevated Serum Levels of Interleukin-5 in Patients
... several days before maximal eosinophilia and then declined. This patient’s lymphocytes showed an increased percentage, ...
... several days before maximal eosinophilia and then declined. This patient’s lymphocytes showed an increased percentage, ...
Current Perspective on In Vivo Molecular Imaging of Immune Cells
... (NK) cells, and other cells. They represent the first line of defense and are less specific than the cells of the adaptive immune system, predominantly comprising T cells and B cells. Each cell type has a well-defined role in the cascade of events that occurs following encounter with a pathogen or t ...
... (NK) cells, and other cells. They represent the first line of defense and are less specific than the cells of the adaptive immune system, predominantly comprising T cells and B cells. Each cell type has a well-defined role in the cascade of events that occurs following encounter with a pathogen or t ...
Review Article Modulation of Adult Hippocampal Neurogenesis by Early-Life
... the type of response observed in adulthood. Indeed it has been shown that some of the proteins involved in immune response to antigens such as LPS-binding protein (LBP) are not expressed during the first week of life [27]. Interestingly LBP expression peaks at PND 14, which might explain the more ro ...
... the type of response observed in adulthood. Indeed it has been shown that some of the proteins involved in immune response to antigens such as LPS-binding protein (LBP) are not expressed during the first week of life [27]. Interestingly LBP expression peaks at PND 14, which might explain the more ro ...
Protozoan Parasite Glycosylphosphatidylinositol Anchors from a
... by various protozoan parasites (8, 10), which are common etiologic agents of medical and veterinary diseases. Glycosylphosphatidylinositol (GPI) anchors are abundant molecules in the membrane of parasitic protozoa (11). Recent studies have documented the immunostimulatory and regulatory activity of ...
... by various protozoan parasites (8, 10), which are common etiologic agents of medical and veterinary diseases. Glycosylphosphatidylinositol (GPI) anchors are abundant molecules in the membrane of parasitic protozoa (11). Recent studies have documented the immunostimulatory and regulatory activity of ...
Granulomatous Reactivation during the Course of a Leprosy
... In this study the leprosy patients included presented with at least one histopathological examination indicating reactivation, determined either by a tuberculoid granulomatous infiltration with a change of classification or by a granulomatous infiltration that persisted for more than two years eithe ...
... In this study the leprosy patients included presented with at least one histopathological examination indicating reactivation, determined either by a tuberculoid granulomatous infiltration with a change of classification or by a granulomatous infiltration that persisted for more than two years eithe ...
Inhaled therapeutics for prevention and treatment of pneumonia Review
... using cytokines or synthetic pathogen-associated molecular pattern analogues and more opportunities for the use of inhaled antimicrobials. These therapeutics are still in their infancy but show great promise. Keywords: amikacin, antifungal, antiviral, aspergillosis, cancer, colistin, cytokine, inhal ...
... using cytokines or synthetic pathogen-associated molecular pattern analogues and more opportunities for the use of inhaled antimicrobials. These therapeutics are still in their infancy but show great promise. Keywords: amikacin, antifungal, antiviral, aspergillosis, cancer, colistin, cytokine, inhal ...
IACFS/ME Conference 2014 Summary
... normal antigens of the host. Auto immune disease is disease caused or significantly promoted by auto-immunity – with production of self-reactive T and B cells. We are in fact developing lymphocytes and are “auto-immune” all the time, but we have mechanisms which recognize and control. Disease occurs ...
... normal antigens of the host. Auto immune disease is disease caused or significantly promoted by auto-immunity – with production of self-reactive T and B cells. We are in fact developing lymphocytes and are “auto-immune” all the time, but we have mechanisms which recognize and control. Disease occurs ...
The nervous system and innate immunity: The neuropeptide
... the cathelicidin family, present in both leukocytes and infected epithelial tissues, also exhibits chemoattractant activity for a several cell types including T cells, monocytes, and neutrophils; LL-37 acts specifically on the fMLP receptor, a G protein coupled receptor13. Other biological effects o ...
... the cathelicidin family, present in both leukocytes and infected epithelial tissues, also exhibits chemoattractant activity for a several cell types including T cells, monocytes, and neutrophils; LL-37 acts specifically on the fMLP receptor, a G protein coupled receptor13. Other biological effects o ...
Role of Hyperbaric Oxygen Therapy in the Treatment of
... postoperative organ/space sternal SSI. Although surgical site infection (SSI) occurs in only 1% to 4% of patients who undergo cardiac surgery via midline sternotomy, it represents a major problem, leading to increased morbidity, prolonged hospitalization with higher cost, and increased mortality [1] ...
... postoperative organ/space sternal SSI. Although surgical site infection (SSI) occurs in only 1% to 4% of patients who undergo cardiac surgery via midline sternotomy, it represents a major problem, leading to increased morbidity, prolonged hospitalization with higher cost, and increased mortality [1] ...
immune system
... • TH cells control the decision whether or not initiate immune response • This decision is achieved through the deletion of the selfreacting lymphocytes, so that responses will only be initiated against non-self. • however, that TH cells themselves require a co-stimulatory signal from non-antigen sp ...
... • TH cells control the decision whether or not initiate immune response • This decision is achieved through the deletion of the selfreacting lymphocytes, so that responses will only be initiated against non-self. • however, that TH cells themselves require a co-stimulatory signal from non-antigen sp ...
ch22 Lymphatics
... capillaries (lymph) to lymphatic vessels to lymph trunks to the thoracic duct or right lymphatic duct to the subclavian veins (blood) (Figure 22.4). 1) Lymph flows as a result of the milking action of skeletal muscle contractions and respiratory movements. 2) It is also aided by lymphatic vessel val ...
... capillaries (lymph) to lymphatic vessels to lymph trunks to the thoracic duct or right lymphatic duct to the subclavian veins (blood) (Figure 22.4). 1) Lymph flows as a result of the milking action of skeletal muscle contractions and respiratory movements. 2) It is also aided by lymphatic vessel val ...
Tips to Remember: What is an allergic reaction
... Antihistamines Allergies are frequently treated by drugs called antihistamines (because they inhibit the activity of histamine). Some contemporary examples are Claritin and Allegra, but antihistamines have been in use since as early as the 1930s and they continue to be an effective way to deal with ...
... Antihistamines Allergies are frequently treated by drugs called antihistamines (because they inhibit the activity of histamine). Some contemporary examples are Claritin and Allegra, but antihistamines have been in use since as early as the 1930s and they continue to be an effective way to deal with ...
1 Mycology is the study of fungi. Fungi include: yeasts, molds – they
... does not grow in the bird itself. Usually the infection does not proceed beyond this pulmonary stage. In the immunosuppressed host however, it may spread through the blood to the meninges and other body areas, often causing cryptococcal meningoencephalitis. Any disease by this yeast is usually calle ...
... does not grow in the bird itself. Usually the infection does not proceed beyond this pulmonary stage. In the immunosuppressed host however, it may spread through the blood to the meninges and other body areas, often causing cryptococcal meningoencephalitis. Any disease by this yeast is usually calle ...
The Lymph Node B Cell Immune Response
... immunogenic antigen: B cells, T cells and antigenpresenting cells (APC). The interacting B cells and T cells both have to express antigen receptors specific to epitopes of the immunogenic antigen. The APC take up and process the immunogenic molecule and present epitopes to the specific responding T ...
... immunogenic antigen: B cells, T cells and antigenpresenting cells (APC). The interacting B cells and T cells both have to express antigen receptors specific to epitopes of the immunogenic antigen. The APC take up and process the immunogenic molecule and present epitopes to the specific responding T ...
- Zaharoff Laboratory
... but also to render tumors more susceptible to CTL-mediated tumor cell lysis. The type I IFNs (IFN-a and IFN-h) show clinical efficacy and are Food and Drug Administration approved for the treatment of chronic hepatitis B and C, AIDS-related Kaposi’s sarcoma, malignant melanoma, follicular lymphoma, ...
... but also to render tumors more susceptible to CTL-mediated tumor cell lysis. The type I IFNs (IFN-a and IFN-h) show clinical efficacy and are Food and Drug Administration approved for the treatment of chronic hepatitis B and C, AIDS-related Kaposi’s sarcoma, malignant melanoma, follicular lymphoma, ...
Common Concepts of Immune Defense
... increased blood flow into the injury site perceptible as redness and heat (rubor, caIor), in order to bring in soluble and cellular defense tools. Postcapillary vasoconstriction is maintained to keep the pathogen at the site of entry. All this lowers the blood flow rate already in the beginning of t ...
... increased blood flow into the injury site perceptible as redness and heat (rubor, caIor), in order to bring in soluble and cellular defense tools. Postcapillary vasoconstriction is maintained to keep the pathogen at the site of entry. All this lowers the blood flow rate already in the beginning of t ...
REVIEW: THE ROLE OF INFLAMMATION IN DEPRESSION
... chemokines and acute phase proteins and anti-inflammatory mediators, the former being in excess (Irwin & Miller 2007, Blume, et al. 2012, Zorrilla et al. 2001). ...
... chemokines and acute phase proteins and anti-inflammatory mediators, the former being in excess (Irwin & Miller 2007, Blume, et al. 2012, Zorrilla et al. 2001). ...
Innate and adaptive immune responses in the lungs
... stimuli. Several studies have shown that airway epithelial cells express on their surface adhesion molecules and secrete various immune molecules such as cytokines, chemokines and other factors (6-11). Through the expression and production of these inflammatory mediators, not only the vascular but a ...
... stimuli. Several studies have shown that airway epithelial cells express on their surface adhesion molecules and secrete various immune molecules such as cytokines, chemokines and other factors (6-11). Through the expression and production of these inflammatory mediators, not only the vascular but a ...
Relevance of sexual dimorphism to regulatory T cells: estradiol
... major histocompatibility complex (MHC) class I–like molecule CD1d.13-15 Although natural ligand(s) of iNKT cells remain unknown, ␣-galactosylceramide (␣-GalCer), a synthetic glycolipid that binds to CD1d, strongly stimulates iNKT cell functions: namely, cytokine production. The hypothesis that iNKT ...
... major histocompatibility complex (MHC) class I–like molecule CD1d.13-15 Although natural ligand(s) of iNKT cells remain unknown, ␣-galactosylceramide (␣-GalCer), a synthetic glycolipid that binds to CD1d, strongly stimulates iNKT cell functions: namely, cytokine production. The hypothesis that iNKT ...