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Origins and means of the immune response
Origins and means of the immune response

... • LAT - Linker for activation of T cells • Functional defect of Lat gene results in – • Lymphoproliferative syndrome – LSP • It is manifested by polyclonal proliferation of CD4+ T cells, secreting chronically in excess cytokines typical for Th2 response ...
Lecture 15 - Adaptive Immunity Day 1 2 slides per page
Lecture 15 - Adaptive Immunity Day 1 2 slides per page

... What promotes an immune response? • Antigens – Usually proteins or polysaccharides – Foreign substance with MW of greater than 10,000 daltons – Examples of antigens: bacterial capsules, cellll walls, ll fl flagella, ll toxins i off b bacteria i ...
TEST immune 2012 markscheme
TEST immune 2012 markscheme

File - BIOLOGY Mound
File - BIOLOGY Mound

... ROUGH NOTES -- IGNORE • Leukocytes: white blood cells. • Phagocytes (innate immune system) Macrophages (engulf pathogens) • B cells (produce antibodies) • Antibodies: proteins that …. • Lymphocytes (T cells and mature b cells) – Helper T cells mature after macrophage antigen presentation…. Effector ...
ORGANIZATION OF THE IMMUNE SYSTEM
ORGANIZATION OF THE IMMUNE SYSTEM

Key words: 1. Pathogen: A microorganism that can cause disease. 2
Key words: 1. Pathogen: A microorganism that can cause disease. 2

File
File

...  The antibody and antigen fit together like a lock and key. This means that the antibody produced to fight the antigen, will bind to that specific antigen only.  T Cells – do not produce antibodies. They attack cells directly.  This is called a CELL MEDIATED RESPONSE.  When the T cell binds to a ...
Herbal Medicines for Immunosuppression
Herbal Medicines for Immunosuppression

Slide 1 - Cloudfront.net
Slide 1 - Cloudfront.net

... •Mast cells release histamine, which causes the capillaries to dilate and become permeable, which allows proteins to escape into the tissues causing swelling ...
Bartonella henselae
Bartonella henselae

1133693644_460426
1133693644_460426

... • Unclassified microorganisms include – Viruses • Incapable of reproducing on their own ...
PowerPoint Presentation - Atypical Cutaneous Leishmaniasis
PowerPoint Presentation - Atypical Cutaneous Leishmaniasis

... T cell Independent Antigens B-1 cells Activated by repeating CHO epitopes that provide crosslinking to induce antigen uptake and activation. Antigen specific immune response Lower affinity, lower numbers, no memory. Primarily IgM. ...
Introduction to Immunity worksheet (LE)
Introduction to Immunity worksheet (LE)

... Innate Immunity worksheet (1) From the word bank, assign each term to the immunity heading with which it is associated. Some terms may fit more than one category and should be placed in all categories that apply. antibodies in breast milk lymphocytes stomach acid, saliva, tears complement first line ...
Lines of Defense and Immunity
Lines of Defense and Immunity

Immune
Immune

... are the most important type of white blood cell involved in acquired immunity. When foreign substances come into contact with lymphocytes, they will either secrete defensive antibodies that mark microbes for elimination or they will directly destroy the infected body cells. Lymphocytes are activated ...
خود ایمنی
خود ایمنی

... D) infection with a microorganism that carries a cross-reactive antigen E) Any of the above. ...
Chapter 13- The Body`s Defense System
Chapter 13- The Body`s Defense System

Evolutionary Genetics
Evolutionary Genetics

... • A Gene Superfamily is a large set of related genes that is divisible into smaller sets or families • Genes in each family are more closely related to each other than to genes in other families • Multigene families within this Superfamily – Antibody Genes – T cell receptor genes – MHC protein genes ...
presentation
presentation

... they are covered in a thick mucus. The mucus contains Immunoglobulin A, which guards entrances, and usually the first antibody a microbe encounters. When an antigen is found, antibodies are triggered by the B cells. The B cell surrounds the antigen and digests it. ...
Body Defenses Against Pathogens
Body Defenses Against Pathogens

... c. differentiation into plasma and memory cells d. plasma cells secrete antibodies e. antibodies bind to antigens to cause: i. agglutination ii. precipitation iii. neutralization iv. complement fixation -cell lysis -opsonization -inflammatory enhancement 2. active vs passive immunity 3. natural vs a ...
Chapter 13
Chapter 13

... Immunity: Cells That Plan for the ...
Understanding HIV and AIDS
Understanding HIV and AIDS

... •New viruses are released from the T cells and they attach to other cells. The process of replication then starts over. ...
Defense Systems
Defense Systems

...  plasma cells secrete antibodies which attach to foreign particle marking them for destruction  memory cells lie dormant until the next attack 3. Antigens are particles which can stimulate receptors on lymphocytes  only part of the foreign invader is antigenic 4. Antibodies are proteins produced ...
A-1 POTASSIUM CHANNEL ANTIBODY
A-1 POTASSIUM CHANNEL ANTIBODY

... change (usually called Morvans Syndrome). This is a rare condition which can resolve spontaneously or following treatment. About 40% have a thymoma or other tumour; and only about 60% of all patients have VGKC antibodies. An increasing number of patients are being identified with a VGKC-antibody-ass ...
Chapter 17: IR to Infectious Disease
Chapter 17: IR to Infectious Disease

... If Ig can bind to viral surface, prevents binding to target cell Or Ig can trigger Complement cascade Or bound Ig can agglutinate viruses to be phagocytized sIgA blocks binding to mucosal surfaces ...
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Immunosuppressive drug

For a list of immunosuppressive drugs, see the transplant rejection page.Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to: Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver) Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, sarcoidosis, focal segmental glomerulosclerosis, Crohn's disease, Behcet's Disease, pemphigus, and ulcerative colitis). Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control).A common side-effect of many immunosuppressive drugs is immunodeficiency, because the majority of them act non-selectively, resulting in increased susceptibility to infections and decreased cancer immunosurveillance. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, lipodystrophy, moon face, liver and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.Immunosuppressive drugs can be classified into five groups: glucocorticoids cytostatics antibodies drugs acting on immunophilins other drugs.
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