Document
... SAID (Glucocorticoids) • Glucocorticoids influence all types of inflammatory events, no matter their cause. They induce the lipocortin1 (annexin-1) synthesis, which then binds to cell membranes preventing the phospholipase A2 from coming into contact with its substrate arachidonic acid. This leads ...
... SAID (Glucocorticoids) • Glucocorticoids influence all types of inflammatory events, no matter their cause. They induce the lipocortin1 (annexin-1) synthesis, which then binds to cell membranes preventing the phospholipase A2 from coming into contact with its substrate arachidonic acid. This leads ...
accelerated atherosclerosis in apoE2/2 mice
... Aims Atherosclerosis is an inflammatory disease with T cell-driven immunoinflammatory responses contributing to disease initiation and progression. We investigated the potential role of regulatory T cells (Tregs) in hyperhomocysteinaemia (HHcy)-accelerated atherosclerosis in apoE2/2 mice. Methods an ...
... Aims Atherosclerosis is an inflammatory disease with T cell-driven immunoinflammatory responses contributing to disease initiation and progression. We investigated the potential role of regulatory T cells (Tregs) in hyperhomocysteinaemia (HHcy)-accelerated atherosclerosis in apoE2/2 mice. Methods an ...
Steel, O`Donoghue et al accepted - Spiral
... histologically normal tissues collected at term from Caesarean section deliveries. In most preterm deliveries there are bacteria present, whether or not there is any histological chorioamnionitis (5). This suggests that the inflammatory response to infection, rather than the actual presence of bacte ...
... histologically normal tissues collected at term from Caesarean section deliveries. In most preterm deliveries there are bacteria present, whether or not there is any histological chorioamnionitis (5). This suggests that the inflammatory response to infection, rather than the actual presence of bacte ...
Biological Activity of Marine Polysaccharides and Animal Health
... Immunostimulatory effects of marine sulfated polysaccharides on dendritic cells Bone marrow cells, activated with GM-CSF, Fucoidan 50 mg/ml, 1 mg/ml of anti-CD40, ELISA TNFa, NO, IL-12 on supernatant ...
... Immunostimulatory effects of marine sulfated polysaccharides on dendritic cells Bone marrow cells, activated with GM-CSF, Fucoidan 50 mg/ml, 1 mg/ml of anti-CD40, ELISA TNFa, NO, IL-12 on supernatant ...
Nitric Oxide and Sepsis
... decreased the severe hypotension produced by administration of LPS. Other groups simultaneously reported similar results indicating that endotoxin increases NO production and prompted the idea that pharmacological inhibition of NOS may be useful in the treatment of inflammation and septic shock. How ...
... decreased the severe hypotension produced by administration of LPS. Other groups simultaneously reported similar results indicating that endotoxin increases NO production and prompted the idea that pharmacological inhibition of NOS may be useful in the treatment of inflammation and septic shock. How ...
Document
... Outer cortex – aggregates of B cells called lymphatic nodules (follicles) – site of plasma cell and memory B cell formation Inner cortex – mainly T cells and dendritic cells Medulla – B cells, antibody producing plasma cells from cortex, and macrophages Copyright 2009, John Wiley & Sons, Inc. ...
... Outer cortex – aggregates of B cells called lymphatic nodules (follicles) – site of plasma cell and memory B cell formation Inner cortex – mainly T cells and dendritic cells Medulla – B cells, antibody producing plasma cells from cortex, and macrophages Copyright 2009, John Wiley & Sons, Inc. ...
In vitro blood mononuclear cells Jenny Clifford
... classified according to what cytokines they secrete (17). Th1 cells, which are mainly focussed on viral combat and the cellular branch of the adaptive immune system, secrete mainly Interferon (IFN) -γ and IL-2 (14-16, 18). This activates primarily macrophages, which in turn secrete TNF-α, IL-6 and ...
... classified according to what cytokines they secrete (17). Th1 cells, which are mainly focussed on viral combat and the cellular branch of the adaptive immune system, secrete mainly Interferon (IFN) -γ and IL-2 (14-16, 18). This activates primarily macrophages, which in turn secrete TNF-α, IL-6 and ...
Signal minus 1: A key factor in immunological tolerance to
... inducing a destructive immune response. In fact, the regional lymph node is a major route of metastasis for many epithelial-derived tumours.^ Nevertheless, it has been recognized for some time that substantial T cell proliferation can occur when tumour cells enter regional lymph nodes."' Despite thi ...
... inducing a destructive immune response. In fact, the regional lymph node is a major route of metastasis for many epithelial-derived tumours.^ Nevertheless, it has been recognized for some time that substantial T cell proliferation can occur when tumour cells enter regional lymph nodes."' Despite thi ...
Classification and Descriptions of Allergic Reactions to Drugs
... antibody-mediated” in the definition above is more correctly replaced by, simply, “antibodymediated.” The term anaphylactoid is used for reactions that may show clinically similar or even identical signs and symptoms but where no immune-mediated mechanism can be shown, for example, reactions caused ...
... antibody-mediated” in the definition above is more correctly replaced by, simply, “antibodymediated.” The term anaphylactoid is used for reactions that may show clinically similar or even identical signs and symptoms but where no immune-mediated mechanism can be shown, for example, reactions caused ...
Document
... parasuis and designated as virulence-associated trimeric autotransporters (VtaA). In this work, we produced 15 recombinant VtaA passenger domains and looked for the presence of antibodies directed against them in immune sera by immunoblotting. After infection with a subclinical dose of H. parasuis N ...
... parasuis and designated as virulence-associated trimeric autotransporters (VtaA). In this work, we produced 15 recombinant VtaA passenger domains and looked for the presence of antibodies directed against them in immune sera by immunoblotting. After infection with a subclinical dose of H. parasuis N ...
Compartmentalizing intestinal epithelial cell toll
... critically promote the normal development of host immune system and prevent adverse colonization by enteric pathogens, thereby contributing to local immune homeostasis [5–7]. The mutualistic relationship between host and microbes may be disrupted by various factors that trigger microbial recognition ...
... critically promote the normal development of host immune system and prevent adverse colonization by enteric pathogens, thereby contributing to local immune homeostasis [5–7]. The mutualistic relationship between host and microbes may be disrupted by various factors that trigger microbial recognition ...
Poster
... has risen for vit. D’s ability to modulate immune responses by signaling through the vitamin D receptor (VDR). Vit. D is obtained through dietary sources, like seafood, or exposure to sun’s UVB rays. Vit. D in its active form can passively diffuse into multiple cell types, such as lymphocytes, while ...
... has risen for vit. D’s ability to modulate immune responses by signaling through the vitamin D receptor (VDR). Vit. D is obtained through dietary sources, like seafood, or exposure to sun’s UVB rays. Vit. D in its active form can passively diffuse into multiple cell types, such as lymphocytes, while ...
FZ Thesis (Abstract-Supplemental)_Final_one
... occurs when FMDV succeeds in overwhelming innate host responses to establish a local site of infection, and then replicates there to allow its further transmission within the host. Infection of cattle generally occurs via the respiratory route by aerosolized virus but can also occur through abrasion ...
... occurs when FMDV succeeds in overwhelming innate host responses to establish a local site of infection, and then replicates there to allow its further transmission within the host. Infection of cattle generally occurs via the respiratory route by aerosolized virus but can also occur through abrasion ...
Insect immunity and its signalling: an overview
... foreign substances and pathogens. In insects, it relies on both humoral and cellular responses that are mediated via certain recognizing receptors and activation of several signalling pathways. Fat body and hemocytes are the origins for the production and secretion of antimicrobial agents and activa ...
... foreign substances and pathogens. In insects, it relies on both humoral and cellular responses that are mediated via certain recognizing receptors and activation of several signalling pathways. Fat body and hemocytes are the origins for the production and secretion of antimicrobial agents and activa ...
Molecular and cellular analysis of immunity in the phytoplasma
... been suggested that immunocytes could play a role in the vectorial capacity of insects leading to an increased interest towards primary immunocyte cultures. We analysed at molecular and cellular level the immune response of the leafhopper Euscelidius variegatus with the aim to provide an in vitro mo ...
... been suggested that immunocytes could play a role in the vectorial capacity of insects leading to an increased interest towards primary immunocyte cultures. We analysed at molecular and cellular level the immune response of the leafhopper Euscelidius variegatus with the aim to provide an in vitro mo ...
Haptoglobin, inflammation and disease
... and TNF-␣, which send signals to adjacent vascular cells to initiate activation of endothelial cells and recruitment of neutrophils. The activated neutrophils, which are first in the line of defence, then aid in the recruitment of other inflammatory cells following extravasation (Kushner, 1993). Neutr ...
... and TNF-␣, which send signals to adjacent vascular cells to initiate activation of endothelial cells and recruitment of neutrophils. The activated neutrophils, which are first in the line of defence, then aid in the recruitment of other inflammatory cells following extravasation (Kushner, 1993). Neutr ...