Paraneoplastic Cerebellar Degeneration
... breast, 1 unknown primary, probably ovarian) contained an antibody with a similar reaction pattern but six other patients with paraneoplastic cerebellar degeneration (1 breast, 2 small cell lung cancer, 2 Hodgkin's disease and 1 "pre-leukemic") did not contain such antibodies. In 1986, Western blot ...
... breast, 1 unknown primary, probably ovarian) contained an antibody with a similar reaction pattern but six other patients with paraneoplastic cerebellar degeneration (1 breast, 2 small cell lung cancer, 2 Hodgkin's disease and 1 "pre-leukemic") did not contain such antibodies. In 1986, Western blot ...
Unit 4 - eduBuzz.org
... can be either innate or acquired. Innate immunity is inborn, non-specific, and does not change over time. Examples include: ...
... can be either innate or acquired. Innate immunity is inborn, non-specific, and does not change over time. Examples include: ...
Aging, Persistent Viral Infections, and Immunosenescence: Can
... when reactivated in later life. Other reactivating herpesviruses such as HSV-1 and HSV-2 can cause blisters (i.e., cold sores) to appear on mucous membranes of the labialis and genitalia. Ironically, it is persistent infection with the clinically asymptomatic and supposedly ‘‘harmless’’ CMV infectio ...
... when reactivated in later life. Other reactivating herpesviruses such as HSV-1 and HSV-2 can cause blisters (i.e., cold sores) to appear on mucous membranes of the labialis and genitalia. Ironically, it is persistent infection with the clinically asymptomatic and supposedly ‘‘harmless’’ CMV infectio ...
Gastritis
... The immune system makes antibodies and other proteins that fight off infection and keep the body healthy. In some disorders, the body mistakenly targets one of its own organs as a foreign protein or infection. It makes antibodies against it and can severely damage or even destroy the organ. Diseases ...
... The immune system makes antibodies and other proteins that fight off infection and keep the body healthy. In some disorders, the body mistakenly targets one of its own organs as a foreign protein or infection. It makes antibodies against it and can severely damage or even destroy the organ. Diseases ...
Predictive, Preventive and Personalized Medicine
... celiac, multiple sclerosis, and myasthenia gravis, etc. Other genetic risk factors confirmed are polymorphisms in specific genes encoding molecules involved in antigen presentation, such as Tap-1 and proteosomes, as well as many other candidate genes. ...
... celiac, multiple sclerosis, and myasthenia gravis, etc. Other genetic risk factors confirmed are polymorphisms in specific genes encoding molecules involved in antigen presentation, such as Tap-1 and proteosomes, as well as many other candidate genes. ...
Importance of the Candida albicans cell wall during
... collaborate with TLR2, perhaps by forming a co-receptor complex, which together amplify recognition responses triggered by the Syk kinase and TLR/MyD88 dependent pathways [22]. Dectin-1-b-glucan interactions are also critical for the activation of inflammasome complexes [23,24]. Phospholipomannan ...
... collaborate with TLR2, perhaps by forming a co-receptor complex, which together amplify recognition responses triggered by the Syk kinase and TLR/MyD88 dependent pathways [22]. Dectin-1-b-glucan interactions are also critical for the activation of inflammasome complexes [23,24]. Phospholipomannan ...
Immune cellular regulation on autoantibody production in pemphigus
... self-antigens. One of the key transcription factors involved in this process is named autoimmune regulator (AIRE) and has been shown to be essential in controlling expression of nearly all the self-antigens, including Dsg3.24 The expression levels of Dsg3 in the thymus define the fate of T-cell deve ...
... self-antigens. One of the key transcription factors involved in this process is named autoimmune regulator (AIRE) and has been shown to be essential in controlling expression of nearly all the self-antigens, including Dsg3.24 The expression levels of Dsg3 in the thymus define the fate of T-cell deve ...
Respiratory syncytial virus therapy and prophylaxis: EDITORIAL R.G. Hegele
... being that RSV is a major cause of serious respiratory illnesses such as bronchiolitis and pneumonia worldwide, yet no safe, effective vaccine or good antiviral therapy is available. In this issue of the European Respiratory Journal, OLSZEWSKA et al. [1] report an exciting advance that could well be ...
... being that RSV is a major cause of serious respiratory illnesses such as bronchiolitis and pneumonia worldwide, yet no safe, effective vaccine or good antiviral therapy is available. In this issue of the European Respiratory Journal, OLSZEWSKA et al. [1] report an exciting advance that could well be ...
Lecture 15
... small non-antigenic molecules that become antigens when bound to proteins (form an antigenic determinant site) Useful for creating antibodies for research and diagnosis ...
... small non-antigenic molecules that become antigens when bound to proteins (form an antigenic determinant site) Useful for creating antibodies for research and diagnosis ...
Macrophages, pathology and parasite persistence in
... conclusively demonstrate TLR-mediated DC activation in vivo. A recent report indicates that lipophosphoglycan of L. major might however be the first defined TLR ligand in these parasites [29]. T cell–DC interactions and the spleen immune response Although a low dose model of infection has recently b ...
... conclusively demonstrate TLR-mediated DC activation in vivo. A recent report indicates that lipophosphoglycan of L. major might however be the first defined TLR ligand in these parasites [29]. T cell–DC interactions and the spleen immune response Although a low dose model of infection has recently b ...
Aalborg Universitet immune cells
... Polybrominated diphenyl ethers (PBDEs) are used in flame retardant mixtures to reduce flammability in electronic equipment, upholstery, textiles, plastics, and building materials [1]. Commercial production of the lower brominated PentaBDE and OctaBDE mixtures was banned in the European Union (EU) in ...
... Polybrominated diphenyl ethers (PBDEs) are used in flame retardant mixtures to reduce flammability in electronic equipment, upholstery, textiles, plastics, and building materials [1]. Commercial production of the lower brominated PentaBDE and OctaBDE mixtures was banned in the European Union (EU) in ...
Immunological and antimicrobial molecules in human tears: a
... reaction, which is mediated by mast cells, neutrophils, ...
... reaction, which is mediated by mast cells, neutrophils, ...
Artificial Immune Systems
... B-cells, killer T-cells which bind to foreign invaders and inject poisonous chemicals into them causing their destruction, and suppressor T-cells which inhibit the action of other immune cells thus preventing allergic reactions and autoimmune diseases. B-cells are responsible for the production and ...
... B-cells, killer T-cells which bind to foreign invaders and inject poisonous chemicals into them causing their destruction, and suppressor T-cells which inhibit the action of other immune cells thus preventing allergic reactions and autoimmune diseases. B-cells are responsible for the production and ...
Immune Therapy Program - The Campbell Family Cancer Research
... often unable to fight cancer by itself. Many people with healthy immune cells are still diagnosed with cancer. Yet, it has been shown that treatments that manipulate the immune system can assist in controlling cancer. As described in Section I, there are many steps during an immune response and many ...
... often unable to fight cancer by itself. Many people with healthy immune cells are still diagnosed with cancer. Yet, it has been shown that treatments that manipulate the immune system can assist in controlling cancer. As described in Section I, there are many steps during an immune response and many ...
Analyzing the antibody against H-Y antigen in hematopoietic cell
... The second procedure, the allogeneic transplant, engrafts stem cells from a donor who is genetically matched to the patient for genes in the human leukocyte antigen (HLA) super-locus. Matching is necessary because the HLA genes govern the interactions between the immune system and all other cells. ...
... The second procedure, the allogeneic transplant, engrafts stem cells from a donor who is genetically matched to the patient for genes in the human leukocyte antigen (HLA) super-locus. Matching is necessary because the HLA genes govern the interactions between the immune system and all other cells. ...
PD-1/PD-L1 Immune Checkpoint Blockade in Non–Small Cell Lung
... Stephen J. Bagley, MD, Joshua M. Bauml, MD, and Corey J. Langer, MD ...
... Stephen J. Bagley, MD, Joshua M. Bauml, MD, and Corey J. Langer, MD ...
Cord Blood Leucocyte Expression of Functionally Significant
... is a cytokine produced primarily by monocytes and macrophages in response to stimulation by IL-1 [8]. Conflicting data in relation to IL-6 expression by resting and stimulated cord and adult leucocytes have been reported. Schibler et al. [9] reported a lower IL-6 production by neonates when compared ...
... is a cytokine produced primarily by monocytes and macrophages in response to stimulation by IL-1 [8]. Conflicting data in relation to IL-6 expression by resting and stimulated cord and adult leucocytes have been reported. Schibler et al. [9] reported a lower IL-6 production by neonates when compared ...
Synergistic Communication between CD4+ T Cells and Monocytes
... concert. Understanding the contributions of each cell type in the context of cell-cell communication is important for effectively designing disease modifying interventions. Here, we present multi-plexed measurement of 48 cytokines from a coculture system of primary human CD4+ T cells and monocytes a ...
... concert. Understanding the contributions of each cell type in the context of cell-cell communication is important for effectively designing disease modifying interventions. Here, we present multi-plexed measurement of 48 cytokines from a coculture system of primary human CD4+ T cells and monocytes a ...
Time course of cigarette smoke-induced pulmonary inflammation in mice
... Groups of mice were exposed to either cigarette smoke or to control air for up to 24 weeks. In response to cigarette smoke, inflammatory cells (i.e. neutrophils, macrophages and lymphocytes) progressively accumulated both in the airways and lung parenchyma of mice. Furthermore, a clear infiltration ...
... Groups of mice were exposed to either cigarette smoke or to control air for up to 24 weeks. In response to cigarette smoke, inflammatory cells (i.e. neutrophils, macrophages and lymphocytes) progressively accumulated both in the airways and lung parenchyma of mice. Furthermore, a clear infiltration ...
Neisseria gonorrhoeae Variation of Lipooligosaccharide Directs Dendritic Cell–Induced T Helper Responses
... DCs. DCs do express the GalNAc-specific C-type lectin MGL [25]. We hypothesized that this lectin might be the major receptor for GC phenotype C. A fusion protein of the extracellular domains of MGL coupled to the human IgG1 Fc tail strongly recognized GC variant C in a dose-dependent manner in an EL ...
... DCs. DCs do express the GalNAc-specific C-type lectin MGL [25]. We hypothesized that this lectin might be the major receptor for GC phenotype C. A fusion protein of the extracellular domains of MGL coupled to the human IgG1 Fc tail strongly recognized GC variant C in a dose-dependent manner in an EL ...