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JS 1
JS 1

... How to manage common-pool resources has been a topic of interest for many scholars. The so-called commons dilemma was made famous by Hardin (1968) as “the tragedy of the commons”. The traditional view is that when there is no regulation, individuals can ignore the costs their decisions impose on oth ...
and D
and D

... disfunction related to liver disease than HCV patients. Co-infections did not worsen patient survival because the two viruses inhibit replication one to an other. HCV inhibits HBV replication. Antiviral treatment with nucleosides has improved the short-term outcome of kidney transplant recipients wi ...
Novocastra™ Liquid Mouse Monoclonal Antibody Thyroid
Novocastra™ Liquid Mouse Monoclonal Antibody Thyroid

... Should be examined after the positive tissue control to verify the specificity of the labeling of the target antigen by the primary antibody. Recommended negative control tissue is skin. Alternatively, the variety of different cell types present in most tissue sections frequently offers negative con ...
Part 1: Mechanisms and Management of Food Allergies
Part 1: Mechanisms and Management of Food Allergies

... T cell lymphocytes detect foreign proteins (antigens) in any form T cells then trigger a series of immunological reactions, mediated by cytokines ...
Spleen
Spleen

... endothelium filled with all types of blood cells, macrophages and plasma cells. See also: Lymphatic system; Lymphoid system In mammals, the spleen has three main functions: first, it represents a large mass of organized lymphatic tissue passed by recirculating lymphocytes, which are able to promptly e ...
Identification of Immunogenic Human Melanoma Antigens in a
Identification of Immunogenic Human Melanoma Antigens in a

... evidence that this concept is correct is that immunization to melanoma vaccines can prevent this cancer in syngeneic mice (2—4).The protection conferred is specific (2), i.e., mice immu nized with control vaccine are not protected against melanoma and melanoma vaccine-immunized mice are not protec ...
Granzyme A activates another way to die
Granzyme A activates another way to die

... cells (approximately 20 lg ⁄ 109 cells) (96), and conservative estimates that approximately one-tenth of CTL granule contents are released into a single synapse with a volume of <5 lm3. Therefore, GzmA synapse concentrations are approximately 2 · 109 lg ⁄ 5 lm3 or approximately 8 lM, a concentration ...
Severe Combined Immunodeficiency
Severe Combined Immunodeficiency

... An excessive number of infections is the most common presenting symptom of infants with SCID. These infections are not usually the same sorts of infections that normal children have, e.g., frequent colds. The infections of the infant with SCID can be much more serious and even life threatening and m ...
The Lymphatic System
The Lymphatic System

... from the body via lymph nodes and develops immune cells (lymphocytes) 2. Fluid Balance: Returns excess fluid to the cardiovascular system ...
没有幻灯片标题
没有幻灯片标题

... maxillary sinus and external ethmoidectomy ...
Sphingolipids and the Balancing of Immune Cell Function: Lessons
Sphingolipids and the Balancing of Immune Cell Function: Lessons

... of these lipid metabolites can directly bind proteins, activate signaling pathways, and affect cellular responses; moreover, in combination, the sphingolipid mediators can finely tune cellular function. Cer binds to a number of signaling proteins such as isozymes of protein kinase C (PKC) (␣, ␦, and ...


... might induce the proliferation of epithelial ovarian cells. IL-6 is produced by epithelial and granular ovarian cells. Physiologically IL-6 regulates the growth of B lymphocytes, in multiple myeloma it is secreted by cancer cells which express the receptor of this cytokine and use IL-6 as a growth f ...
Sarcoidosis
Sarcoidosis

Equine allogeneic bone marrow-derived mesenchymal stromal cells
Equine allogeneic bone marrow-derived mesenchymal stromal cells

Effects of temperature on fish immune defences
Effects of temperature on fish immune defences

... This thermosensitive step can be a very early event, such as Tcell receptor–CD3 transmembrane signalling and/or G-protein activation. Low temperatures would exert their influence at the level of the T helper plasma membrane. Consequently, studies were conducted to identify the event preceding protei ...
Sarcoidosis
Sarcoidosis

... preparation of sarcoid tissue material into the skin. • Unique lump formed at the point of injection is considered positive for sarcoidosis. ...
Gastrointestinal Disease
Gastrointestinal Disease

... The Gut associated lymphoid tissue (GALT) is the largest aggregation of immune competent cells in the body. The loosely aggregated lymphoid tissue in the lamnia propria,and the so called Peyers patches, as well as the tonsillar rings of Waldeyer forms the GALT. All antigens which get into the post m ...
Sarcoidosis
Sarcoidosis

... preparation of sarcoid tissue material into the skin. • Unique lump formed at the point of injection is considered positive for sarcoidosis. ...
Listeria Monocytogenes Protein Fraction Induces Dendritic Cells
Listeria Monocytogenes Protein Fraction Induces Dendritic Cells

Immunology
Immunology

... primary response to an antigen. It is the first immunoglobulin to be synthesized by the neonate, its presence fetal blood indicates intra-uterine infection. Due to its pentameric structure, serum IgM has a higher valency than the other isotypes in binding antigens with many repeating epitopes such a ...
Development of structured treatment interruption strategies for HIV
Development of structured treatment interruption strategies for HIV

... and possible re-initiation, perhaps through several cycles of these steps. However, although STI regimens have been proposed based on experience and expert opinion and have been studied clinically in both humans and animals (Lisziewicz et al., 1999; Lori et al., 2000; Lori and Lisziewicz, 2001; Rose ...
Futility of the autoimmune orthodoxy in multiple sclerosis research
Futility of the autoimmune orthodoxy in multiple sclerosis research

TGFb Treatment Enhances Glioblastoma
TGFb Treatment Enhances Glioblastoma

Inflammatory Micro-Environmental Cues of
Inflammatory Micro-Environmental Cues of

... In all the AAA tissues analyzed, but none of the control aortas, the immunohistochemical analysis revealed a prototypic organization of the immune infiltrates in the media and the adventitia where massive CD20+ B cell follicles were surrounded by T cells (CD3) (Fig. 1A), suggestive of mature aortic ...
Facts and Concepts
Facts and Concepts

... Functions of the major parts of the eye: Sclera or Scleroid Layer – (white of eye) a tough protective layer of connective tissue that helps maintain the shape of the eye and provides an attachment for the muscles that move the eye Cornea - the clear, dome-shaped part of the sclera covering the front ...
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Immunosuppressive drug

For a list of immunosuppressive drugs, see the transplant rejection page.Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to: Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver) Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, sarcoidosis, focal segmental glomerulosclerosis, Crohn's disease, Behcet's Disease, pemphigus, and ulcerative colitis). Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control).A common side-effect of many immunosuppressive drugs is immunodeficiency, because the majority of them act non-selectively, resulting in increased susceptibility to infections and decreased cancer immunosurveillance. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, lipodystrophy, moon face, liver and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.Immunosuppressive drugs can be classified into five groups: glucocorticoids cytostatics antibodies drugs acting on immunophilins other drugs.
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