Chitosan, but not bacterial siderophores, induces a partial
... Activated dendritic cells are known to synthetize many different proteins. In addition to the well known cytokine expression, which is even a test to check for dendritic cell activation with various stimuli [14], [6] [7], recent work has also shown that activated dendritic cells secrete many other p ...
... Activated dendritic cells are known to synthetize many different proteins. In addition to the well known cytokine expression, which is even a test to check for dendritic cell activation with various stimuli [14], [6] [7], recent work has also shown that activated dendritic cells secrete many other p ...
anterior_uveitis_in_cats
... dexamethasone 0.1%; other topical steroids (such as betamethasone, hydrocortisone) are less effective in the treatment of inflammation within the eye—stopping topical steroids abruptly may result in rebound of inflammation of the eye • Subconjunctival steroids are medications that are administered b ...
... dexamethasone 0.1%; other topical steroids (such as betamethasone, hydrocortisone) are less effective in the treatment of inflammation within the eye—stopping topical steroids abruptly may result in rebound of inflammation of the eye • Subconjunctival steroids are medications that are administered b ...
Anterior Uveitis in Cats
... dexamethasone 0.1%; other topical steroids (such as betamethasone, hydrocortisone) are less effective in the treatment of inflammation within the eye—stopping topical steroids abruptly may result in rebound of inflammation of the eye • Subconjunctival steroids are medications that are administered b ...
... dexamethasone 0.1%; other topical steroids (such as betamethasone, hydrocortisone) are less effective in the treatment of inflammation within the eye—stopping topical steroids abruptly may result in rebound of inflammation of the eye • Subconjunctival steroids are medications that are administered b ...
2016 BIOTECH PRIMER WEEKLY
... Another longevity company backed by legendary players is California Life Sciences (Calico; South San Francisco, CA), founded in 2013 with financial backing from big data giant Google. Arthur Levinson, who made his name first as head of R&D and subsequently CEO and chairman of Genentech (South San Fr ...
... Another longevity company backed by legendary players is California Life Sciences (Calico; South San Francisco, CA), founded in 2013 with financial backing from big data giant Google. Arthur Levinson, who made his name first as head of R&D and subsequently CEO and chairman of Genentech (South San Fr ...
Gene expression profile predicting the response to anti
... Abstract: Anti-tumor necrosis factor (anti-TNF) antibodies therapy is a new choice for patients with inflammatory bowel disease (IBD). However, not all patients show favorable response to anti-TNF therapy. Our aim of this study is to identify differentially expressed genes (DEGs) that could predict ...
... Abstract: Anti-tumor necrosis factor (anti-TNF) antibodies therapy is a new choice for patients with inflammatory bowel disease (IBD). However, not all patients show favorable response to anti-TNF therapy. Our aim of this study is to identify differentially expressed genes (DEGs) that could predict ...
The polygenic nature of inhibitors in hemophilia A: results from the
... infused factor remains a serious obstacle for patients and care givers. The reasons that only a fraction of patients, 10%-15% overall and typically 20%-30%1 among those with severe disease, develop Abs remain obscure, but there are several observations indicating that genetic factors are of major im ...
... infused factor remains a serious obstacle for patients and care givers. The reasons that only a fraction of patients, 10%-15% overall and typically 20%-30%1 among those with severe disease, develop Abs remain obscure, but there are several observations indicating that genetic factors are of major im ...
Are Obesity-Related Insulin Resistance and Type 2 Diabetes
... IgGs are also seen during obesity-related insulin resistance (11). Furthermore, transfer of CD8+ T cells (12,13) or high-fat diet (HFD)-induced IgG antibodies (11) can aggravate insulin resistance without affecting obesity, while T- or B-cell depletion or genetic deficiency improves insulin resistanc ...
... IgGs are also seen during obesity-related insulin resistance (11). Furthermore, transfer of CD8+ T cells (12,13) or high-fat diet (HFD)-induced IgG antibodies (11) can aggravate insulin resistance without affecting obesity, while T- or B-cell depletion or genetic deficiency improves insulin resistanc ...
HIPV3/EboGP aerosol HIPV3/EboGP IN/IT HPIV3 VRP
... Aerosolized vaccine induces strong systemic (high antibody and T cell responses) and mucosal responses that can be accelerated with a second dose. Aerosolized vaccine confered cross-protection and can protect against viral hemorrhagic fever. Aerosolized vaccine can be easly implemented in case of an ...
... Aerosolized vaccine induces strong systemic (high antibody and T cell responses) and mucosal responses that can be accelerated with a second dose. Aerosolized vaccine confered cross-protection and can protect against viral hemorrhagic fever. Aerosolized vaccine can be easly implemented in case of an ...
Recent progress in vaccines
... vaccine formulation and for establishing correlates/surrogates of protection in clinical trials. In particular, the T cell-based mechanisms mediate protection indirectly, that is, promoting an inflammatory response with recruitment of soluble (antimicrobial peptides, cytokines, chemokines) and cellu ...
... vaccine formulation and for establishing correlates/surrogates of protection in clinical trials. In particular, the T cell-based mechanisms mediate protection indirectly, that is, promoting an inflammatory response with recruitment of soluble (antimicrobial peptides, cytokines, chemokines) and cellu ...
Systemic features of immune recognition in the gut
... signals recognized by PRRs seem to indicate infection events and thus also, indirectly, the presence of a pathogen. However, recent studies show that PRRs can promote down-regulatory type responses as well as proinflammatory responses. For example, it has been shown that TLR2 is required for the ind ...
... signals recognized by PRRs seem to indicate infection events and thus also, indirectly, the presence of a pathogen. However, recent studies show that PRRs can promote down-regulatory type responses as well as proinflammatory responses. For example, it has been shown that TLR2 is required for the ind ...
T cell receptor-transgenic mouse models for studying cellular
... responses to ovalbumin were analyzed in subcutaneously infected BALB/c mice that had previously received 2.5U 106 TCR-transgenic T cells from Do11.10 mice. Transgenic T cells accumulated in the draining lymph nodes and spleens of mice infected with ovalbumin-expressing Salmonella but not in mice inf ...
... responses to ovalbumin were analyzed in subcutaneously infected BALB/c mice that had previously received 2.5U 106 TCR-transgenic T cells from Do11.10 mice. Transgenic T cells accumulated in the draining lymph nodes and spleens of mice infected with ovalbumin-expressing Salmonella but not in mice inf ...
Locally delivered polyclonal antibodies potentiate the efficacy
... renewed attention directed both to understanding mechanisms of antibiotic resistance, as well as to developing alternative antimicrobial methods.7,12-14 Although new de novo ...
... renewed attention directed both to understanding mechanisms of antibiotic resistance, as well as to developing alternative antimicrobial methods.7,12-14 Although new de novo ...
Immune Health - Naturally - Professional Complementary Health
... The immune system is an amazing and complex work of nature; it does an incredible job defending the body against any number of illnesses and infections, at least when it is functioning properly. Unfortunately, patients sometimes relate a lack of symptoms to being well and/or having/possessing a stro ...
... The immune system is an amazing and complex work of nature; it does an incredible job defending the body against any number of illnesses and infections, at least when it is functioning properly. Unfortunately, patients sometimes relate a lack of symptoms to being well and/or having/possessing a stro ...
Cancer Immunotherapy: Whence and Whither
... on cancer cells. There is anecdotal evidence that diabetic patients with cancer who are treated with metformin for their diabetic condition respond better to cancer therapy than patients not treated with metformin. This relationship has recently received support from a large electronic records data ...
... on cancer cells. There is anecdotal evidence that diabetic patients with cancer who are treated with metformin for their diabetic condition respond better to cancer therapy than patients not treated with metformin. This relationship has recently received support from a large electronic records data ...
Thai Journal of Veterinary Medicine
... TLRs are activated by bacterial and virus infection and have been reported in Fenneropenaeus chinensis and ...
... TLRs are activated by bacterial and virus infection and have been reported in Fenneropenaeus chinensis and ...
Consulta: subjectFacets:"Clinical aspects" Registros recuperados: 5
... Autores: Nogueira,R. M. B.; Sakate,M.; Sangiorgio,F.; Laposy,C. B.; Melero,M. The present study aimed at evaluating clinical and laboratory aspects during experimental envenomation by Crotalus durissus terrificus in dogs treated with antiophidic serum. Twenty-one dogs were divided into three groups ...
... Autores: Nogueira,R. M. B.; Sakate,M.; Sangiorgio,F.; Laposy,C. B.; Melero,M. The present study aimed at evaluating clinical and laboratory aspects during experimental envenomation by Crotalus durissus terrificus in dogs treated with antiophidic serum. Twenty-one dogs were divided into three groups ...
... powerful systemic activation of Vγ9Vδ2-T cells in vivo and that these effects are strongly associated with the occurrence of an acute phase response (APR), the effect of NBP on the induction of APC markers on circulating Vγ9Vδ2-T cells and the potential of statin pretreatment of patients to inhibit ...
Streptococcus pneumoniae Responses Without Altered
... cell numbers in the spleen and thymus with a more modest reduction in the bone marrow (28, 29). Compared with other cell types, B lymphocytes were found to be preferentially depleted in the spleen and bone marrow, and CD4/CD8 double-positive (DP) T cell precursors were preferentially diminished in t ...
... cell numbers in the spleen and thymus with a more modest reduction in the bone marrow (28, 29). Compared with other cell types, B lymphocytes were found to be preferentially depleted in the spleen and bone marrow, and CD4/CD8 double-positive (DP) T cell precursors were preferentially diminished in t ...
A daunting task: manipulating leukocyte function with RNAi
... specific RNAi molecules such as miRNA mimics and siRNAs. RNAi-induced gene silencing mirrors the inhibitory effects of conventional pharmaceuticals, primarily protein-based drugs such as antibodies and vaccines and small molecules, which mainly block their targets’ function. However, some disease-re ...
... specific RNAi molecules such as miRNA mimics and siRNAs. RNAi-induced gene silencing mirrors the inhibitory effects of conventional pharmaceuticals, primarily protein-based drugs such as antibodies and vaccines and small molecules, which mainly block their targets’ function. However, some disease-re ...
Peer-reviewed Article PDF
... for each patient due to the differences in MHCs, and is thus expensive. As one countermeasure, a peptide panel of major T-cell epitopes for each MHC has been reported [14]. On the other hand, longer peptides are able to reduce the number of total peptides and facilitate screening, although the synth ...
... for each patient due to the differences in MHCs, and is thus expensive. As one countermeasure, a peptide panel of major T-cell epitopes for each MHC has been reported [14]. On the other hand, longer peptides are able to reduce the number of total peptides and facilitate screening, although the synth ...
Dissecting the human immunologic memory for pathogens
... exposed over the last several years (25). This finding, which is now corroborated by high throughput repertoire analyses (Dora Pinto, unpublished data), would be consistent with a role for polyclonal activation of memory B cells in replacing old plasma cells, which are displaced from the bone marrow ...
... exposed over the last several years (25). This finding, which is now corroborated by high throughput repertoire analyses (Dora Pinto, unpublished data), would be consistent with a role for polyclonal activation of memory B cells in replacing old plasma cells, which are displaced from the bone marrow ...
Role of Toll-like receptors in airway inflammation
... allergic rhinitis. We also sought to map cellular and molecular changes occurring as a result of allergen-specific immunotherapy. In the first two studies, a distinct expression of TLRs was demonstrated in subsets of B and T lymphocytes isolated from human tonsils. The expression levels seemed to be ...
... allergic rhinitis. We also sought to map cellular and molecular changes occurring as a result of allergen-specific immunotherapy. In the first two studies, a distinct expression of TLRs was demonstrated in subsets of B and T lymphocytes isolated from human tonsils. The expression levels seemed to be ...