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Ms. S Lymphatic Notes File
Ms. S Lymphatic Notes File

... • -formed when the capillaries merge w/ one another and are located closer to the heart • -thicker walls than the capillaries • -have valves to prevent the backflow of lymph (keep lymph traveling toward the heart) • -as the vessels extend toward the heart, they increase in size and form larger lymph ...
Current Opinion in Immunology
Current Opinion in Immunology

... The use of SIT for AID has lagged behind SIT for allergy. This may be because AIDs are more heterogeneous than allergic diseases; the disease-initiating or target antigen may not be known; and/or the immune pathogenesis of AID is associated with epitope spreading [18] and substantial tissue damage m ...
Living Environment Immune System and Disease Aim What are the
Living Environment Immune System and Disease Aim What are the

... Active Immunity(body can mount an attack) Vaccine: The injection of a weakened form of a pathogen to produce immunity History of vaccines Edward Jenner used cowpox to produce immunity to smallpox in the 1800’s ...
Document
Document

The Immune System Body Defenses Innate Defenses Surface
The Immune System Body Defenses Innate Defenses Surface

Dealing with Garbage is the Immune System`s Main Job
Dealing with Garbage is the Immune System`s Main Job

... promotes antibody production by B cells to facilitate trash clearance. Dendritic cells at the site pick up garbage that contains PAMPS or DAMPS. They respond to the stimulus, spread a local cytokine alarm, mature, and then run to the lymph node to direct T cells to act. During their maturation and t ...
Immunity - Seattle Central College
Immunity - Seattle Central College

... – We each have thousands of different populations of B & Tcells, each with unique antigen receptors ...
IMMUNOLOGY SIMPLIFIED Autoimmune diseases
IMMUNOLOGY SIMPLIFIED Autoimmune diseases

... this enhanced protection against infections is a greater risk for autoimmune disorders. • May have something to do with the GI microbiome and hormonal influences • Animals raised without a gut microbiome show no gender differences in autoimmunity • Eunuchs (castrated males) have the same risk of aut ...
CD8 T cells
CD8 T cells

... The cytotoxic granules are released only in the direction of the target cell, aligned along the immune synapse, to avoid non-specific bystander damage to healthy surrounding tissue (see Figure 1). CD8+ T cells are able to release their granules, kill an infected cell, then move to a new target and k ...
CD8+ T Cells
CD8+ T Cells

... The cytotoxic granules are released only in the direction of the target cell, aligned along the immune synapse, to avoid non-specific bystander damage to healthy surrounding tissue (see Figure 1). CD8+ T cells are able to release their granules, kill an infected cell, then move to a new target and k ...
bahan kuliah eksperimentasi immunofarmakologi
bahan kuliah eksperimentasi immunofarmakologi

... – induction sites for immune responses ...
test question answers
test question answers

... 1. Innate Immunity: defense that is active immediately upon exposure to pathogens and that is the same whether or not the pathogen has been encountered previously. 2. Class I MHCs: found on the surface of nearly all nucleated cells and that functions in identification of infected cells by cytotoxic ...
Congratulations / Félicitations - Canadian Society for Immunology
Congratulations / Félicitations - Canadian Society for Immunology

... tolerance versus activation. She is the Co-Director of the Campbell Family Institute for Breast Cancer Research and the Director of the Cancer Immune Therapy Program at the Ontario Cancer Institute/Princess Margaret Cancer Centre. Dr. Ohashi is also a Senior Scientist at the Ontario Cancer Institute ...
Lecture 4: Host Response to Infection
Lecture 4: Host Response to Infection

Chap 34 - Resistance of the Body to Infection
Chap 34 - Resistance of the Body to Infection

... B. develops in the preprocessing of T lymphocytes in the thymus and B lymphocytes in the bone marrow C. suppressor T cells: 1. function to counteract autoimmune antibodies 2. counter act against sensitized helper cells and sensitized cytotoxic T cells D. autoimmune diseases due to failure of toleran ...
Lymphatic system
Lymphatic system

Vaccines PPT - Alevelsolutions
Vaccines PPT - Alevelsolutions

... 5. Vaccines maybe taken orally or by injection. If taken orally they maybe be broken down by enzymes or not absorbed into the blood as the molecules maybe too large. 6. Booster vaccines maybe given after several years to make sure memory cells are still being produced. ...
immune system - Doral Academy Preparatory
immune system - Doral Academy Preparatory

... • Viral and bacterial infections are by far the most common causes of illness for most people. They cause things like colds, influenza, measles, mumps, malaria, AIDS and so on. The job of your immune system is to protect your body from these infections. The immune system protects you in three diffe ...
IMMUNOLOGY
IMMUNOLOGY

... presenting self-proteins, self-reactive T cells are deleted from the repertoire as a result of tolerance (also known as negative selection which occurs in the thymus). Autoantigens An autoantigen is usually a normal protein or complex of proteins (and sometimes DNA or RNA) that is recognized by the ...
Block B Towaki, Brian, Julio, Jeff Antigens and Antibodies
Block B Towaki, Brian, Julio, Jeff Antigens and Antibodies

... • Explain why antibiotics are effective against bacteria but not against viruses. ...
Acting Out the Immune Response - The American Association of
Acting Out the Immune Response - The American Association of

1. dia
1. dia

... Edema with inflammation is not trivial at all: Marked laryngeal edema such that the airway is narrowed. This is life-threatening. Thus, fluid collections can be serious depending upon their location. ...
1 Immunoglobulins – vitally important constituents of our blood
1 Immunoglobulins – vitally important constituents of our blood

... By binding to cells, immunoglobulins have an effect on the control of inflammatory processes, on the regeneration of destroyed tissue after injuries or surgical operations and also on the maintenance of organ functions. They are important for the communication between our immune system and the nervo ...
Intro to the Lymphatic System
Intro to the Lymphatic System

... Antigen Presentation – present fragments of the antigens they’ve eaten on cell surface, for T cells to recognize Secrete monokines, that further activate T cells ...
The Immune System
The Immune System

... cells in the bone marrow B-cells: • mature in the bone marrow ...
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Molecular mimicry

Molecular mimicry is defined as the theoretical possibility that sequence similarities between foreign and self-peptides are sufficient to result in the cross-activation of autoreactive T or B cells by pathogen-derived peptides. Despite the promiscuity of several peptide sequences which can be both foreign and self in nature, a single antibody or TCR (T cell receptor) can be activated by even a few crucial residues which stresses the importance of structural homology in the theory of molecular mimicry. Upon the activation of B or T cells, it is believed that these ""peptide mimic"" specific T or B cells can cross-react with self-epitopes, thus leading to tissue pathology (autoimmunity). Molecular mimicry is a phenomenon that has been just recently discovered as one of several ways in which autoimmunity can be evoked. A molecular mimicking event is, however, more than an epiphenomenon despite its low statistical probability of occurring and these events have serious implications in the onset of many human autoimmune disorders. In the past decade the study of autoimmunity, the failure to recognize self antigens as ""self,"" has grown immensely. Autoimmunity is a result of a loss of immunological tolerance, the ability for an individual to discriminate between self and non-self. Growth in the field of autoimmunity has resulted in more and more frequent diagnosis of autoimmune diseases. Consequently, recent data show that autoimmune diseases affect approximately 1 in 31 people within the general population. Growth has also led to a greater characterization of what autoimmunity is and how it can be studied and treated. With an increased amount of research, there has been tremendous growth in the study of the several different ways in which autoimmunity can occur, one of which is molecular mimicry. The mechanism by which pathogens have evolved, or obtained by chance, similar amino acid sequences or the homologous three-dimensional crystal structure of immunodominant epitopes remains a mystery.
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