Module 023806: Advanced topics in Immunology
... Insulin-dependent diabetes mellitus Type I diabetes). (an example of cellular damage). A relatively common autoimmune disease leading to the destruction of insulin-producing cells (beta cells) and consequently increased levels of blood sugar. First, cytotoxic T cells attack the beta cells leading to ...
... Insulin-dependent diabetes mellitus Type I diabetes). (an example of cellular damage). A relatively common autoimmune disease leading to the destruction of insulin-producing cells (beta cells) and consequently increased levels of blood sugar. First, cytotoxic T cells attack the beta cells leading to ...
Chapter 13 Hypersensitivity Reactions
... required for isotype switching to IgE Effector phase - when the person is re-exposed to the antigen it binds to the IgE bound to mast cells/basophils - mast cells degranulate releasing histamine, prostaglandins, leukotrienes and platelet activating factors, all of which increase inflammation - these ...
... required for isotype switching to IgE Effector phase - when the person is re-exposed to the antigen it binds to the IgE bound to mast cells/basophils - mast cells degranulate releasing histamine, prostaglandins, leukotrienes and platelet activating factors, all of which increase inflammation - these ...
PowerPoint Presentation - I. Introduction to class
... Myasthenia gravis: Progressive muscle weakness. Antibodies block acetylcholine receptors at neuromuscular synapse. Affects 25,000 Americans (mainly women). Today most patients survive when treated with drugs or immunosuppressants. ...
... Myasthenia gravis: Progressive muscle weakness. Antibodies block acetylcholine receptors at neuromuscular synapse. Affects 25,000 Americans (mainly women). Today most patients survive when treated with drugs or immunosuppressants. ...
lecture08_C
... • How are antibodies made? – B cells • Lymphocytes that make antibodies • Have B cell receptors on surface • 100 million different types of B cells, each with different surface receptors • B cell receptors are so diverse they can recognize every organic molecule ...
... • How are antibodies made? – B cells • Lymphocytes that make antibodies • Have B cell receptors on surface • 100 million different types of B cells, each with different surface receptors • B cell receptors are so diverse they can recognize every organic molecule ...
Pathogens and the immune system
... • Have B cell receptors on surface • 100 million different types of B cells, each with different surface receptors • B cell receptors are so diverse they can recognize every organic molecule ...
... • Have B cell receptors on surface • 100 million different types of B cells, each with different surface receptors • B cell receptors are so diverse they can recognize every organic molecule ...
The contrasting role of B7-H3 Kimberly A. Hofmeyer* , Anjana Ray*
... knockout mice developed EAE earlier as well as more severe airway inflammation under conditions in which T helper cells differentiated toward Th1 rather than Th2 (11). These results are in direct contrast to the previously discussed observations in another B7-H3 knockout ...
... knockout mice developed EAE earlier as well as more severe airway inflammation under conditions in which T helper cells differentiated toward Th1 rather than Th2 (11). These results are in direct contrast to the previously discussed observations in another B7-H3 knockout ...
1. The Cell-Mediated Immune Response
... • activated CTLs express a protein called Fas-ligand when they encounter a cell presenting an MHC class I-peptide complex that binds their T cell receptor • Fas-ligand sets off a series of events that result in the destruction of the infected cell’s DNA and its proteins (i.e., cell death!) ...
... • activated CTLs express a protein called Fas-ligand when they encounter a cell presenting an MHC class I-peptide complex that binds their T cell receptor • Fas-ligand sets off a series of events that result in the destruction of the infected cell’s DNA and its proteins (i.e., cell death!) ...
Elucidation of the pathogenic mechanisms of allergic and
... deficient (Il1rn-/-) mice. In this project, we showed that Dectin-1 and Dectin-2, members of C-type lection family, are important for the induction of Th17 cells and play essential roles in the host defense against fungal infection. Furthermore, we showed that Dcir, another C-type lectin, is importa ...
... deficient (Il1rn-/-) mice. In this project, we showed that Dectin-1 and Dectin-2, members of C-type lection family, are important for the induction of Th17 cells and play essential roles in the host defense against fungal infection. Furthermore, we showed that Dcir, another C-type lectin, is importa ...
31.4 Immunity and Technology KEY CONCEPT help keep a person healthy.
... through conjugation. Resistance is quickly spread through many bacteria. ...
... through conjugation. Resistance is quickly spread through many bacteria. ...
Chapter_02_notes_large - Welcome to people.pharmacy.purdue
... 1. Point mutations introduced to V regions 2. 106 times higher mutation rate 3. Usually targets the CDR ...
... 1. Point mutations introduced to V regions 2. 106 times higher mutation rate 3. Usually targets the CDR ...
Nucleoboost is a Single Cell Protein (SCP)
... economically feasible given the technology required, so the use of waste products from other commercially viable processes has to be considered. This protein source is inexpensive, contains nucleotides that are essential for optimal lymphocyte function and is also immunogenic, resulting in nonspecif ...
... economically feasible given the technology required, so the use of waste products from other commercially viable processes has to be considered. This protein source is inexpensive, contains nucleotides that are essential for optimal lymphocyte function and is also immunogenic, resulting in nonspecif ...
File
... Are more virulent and can cause diseases in a normal person. • Opportunistic pathogens : Are typically members of normal flora and cause diseases when they are introduced into unprotected sites, usually occur in people with underlying conditions. ...
... Are more virulent and can cause diseases in a normal person. • Opportunistic pathogens : Are typically members of normal flora and cause diseases when they are introduced into unprotected sites, usually occur in people with underlying conditions. ...
Monoclonal Antibodies
... inhibiting growth, or interfering with a key function. B. mAbs was modified for delivery of a toxin, radioisotope, cytokine or other active conjugates. C. it is also possible to design bispecific antibodies that can bind with their Fab regions both to target ...
... inhibiting growth, or interfering with a key function. B. mAbs was modified for delivery of a toxin, radioisotope, cytokine or other active conjugates. C. it is also possible to design bispecific antibodies that can bind with their Fab regions both to target ...
Humoral Immunity Antibodies.
... • Antibody dependant cell mediated cytotoxicity: Antibodies attached to target cell cause destruction by non specific immune system cells. ...
... • Antibody dependant cell mediated cytotoxicity: Antibodies attached to target cell cause destruction by non specific immune system cells. ...
Introduction to Immunology and Immunotoxicology
... How do we evaluate for immunosuppression or immunostimulation after chemical exposure? ...
... How do we evaluate for immunosuppression or immunostimulation after chemical exposure? ...
Congenital and Acquired Immunodeficiency Diseases (not HIV)
... Congenital malformation that results in defective development of the thymus and the parathyroid glands. Deficient T cell maturation. Absent parathyroids cause abnormal calcium homeostasis and muscle twitching (tetany). Abnormal development of the heart. Facial deformities. Peripheral T cells are abs ...
... Congenital malformation that results in defective development of the thymus and the parathyroid glands. Deficient T cell maturation. Absent parathyroids cause abnormal calcium homeostasis and muscle twitching (tetany). Abnormal development of the heart. Facial deformities. Peripheral T cells are abs ...
White Blood Cell
... and foreign substances (parts of a germ can trigger the immune system). There are billions of cells in the immune system. Another way to look at the immune system is that it gobbles up germs cells. ...
... and foreign substances (parts of a germ can trigger the immune system). There are billions of cells in the immune system. Another way to look at the immune system is that it gobbles up germs cells. ...
