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Cytokine responses in metal-induced allergic contact in  Jacob Taku Minang
Cytokine responses in metal-induced allergic contact in Jacob Taku Minang

... potentially dangerous substances. These cells are thought to recognise particular highly conserved pathogen-associated molecular patterns or PAMP’s (e.g carbohydrate structures such as lypopolysaccharides; LPS) present on many different microorganisms (reviewed in Franc et al., 1999; Teixeira et al. ...
(pdf version)
(pdf version)

... vertebrate nervous system such as neural induction, morphogenesis of the neural tube, patterning of the brain, differentiation and migration of neurons, axon guidance, synaptogenesis and the regulation of neuronal survival. The course is designed to be interactive and will include lectures, student ...
nuclear hormone receptors enable macrophages and dendritic cells
nuclear hormone receptors enable macrophages and dendritic cells

Induction of inhibitory central nervous system-derived and
Induction of inhibitory central nervous system-derived and

COMPARISON OF CYCLOSPORIN A WITH MITOMYCINC AND GAMMA
COMPARISON OF CYCLOSPORIN A WITH MITOMYCINC AND GAMMA

... these procedures may have a negative affect on the structure/expression of HLADR molecules, as well as cell viability (Kasakura and Lowenstein, 1967; Mettler et al., 1985; Malinowski et al., 1992). Since HLA-DR molecules on the surface of the stimulator cells provide the primary activation signal fo ...
Transferrin and the Transferrin Receptor: Of Magic Bullets
Transferrin and the Transferrin Receptor: Of Magic Bullets

CARBON NANOTUBES AS CARRIERS FOR DELIVERY OF BIOACTIVE AND THERAPEUTIC  AGENTS: AN OVERVIEW  Review Article   
CARBON NANOTUBES AS CARRIERS FOR DELIVERY OF BIOACTIVE AND THERAPEUTIC  AGENTS: AN OVERVIEW  Review Article   

... some  organic  groups  to  the  sidewalls  and/or  tips  of  the  CNTs.  Briefly,  purified  SWNTs  and  aniline  are  mixed  together.  Under  the  pressure  from  the  mixing  force,  the  outermost  nanotubes  from  the  bundle  is  librated  and  is  exposed  to  the  reactive  agent.  Thus,  th ...
Chemical basis of ABO subgroups
Chemical basis of ABO subgroups

... Weak-subgroups/phenotypes are potential windows into the biochemistry of the ABO blood group system, due to the absence of dominating structures, and/or enhancement of trace antigens caused by a loss in normal competition. The aim of this thesis was to gain insights into chemical basis of the ABO sy ...
Full Text - Wyno Academic Journals
Full Text - Wyno Academic Journals

... metabolic processes leading to cellular death. The immune system of an animal is a series of processes to kill pathogens in the body, with naturally occurring AMPs being that first active line of defense. The second line of the active immune system when infections occur is generally focused around t ...
Characterization of thymic hyperplasia associated with autoimmune
Characterization of thymic hyperplasia associated with autoimmune

... Autoimmune myasthenia gravis (MG) is a muscular disease mediated by autoantibodies, mainly directed against the acetylcholine receptor (AChR). The pathogenic antibodies are especially produced in the thymus, which is often characterized by a hyperplasia with germinal centers. Recent studies demonstr ...
ABSTRACT Title of Document:
ABSTRACT Title of Document:

... than those infected with Mtb, or cells derived from NOX2 deficient mice. NuoG also inhibited apoptosis in human alveolar macrophages in a NOX2 dependent manner. These data suggest that reduction of phagosomal ROS is important for inhibition of apoptosis. Consistent with this hypothesis, Mtb deficie ...
iiiiiiiiii - Cancer Research
iiiiiiiiii - Cancer Research

... (1) The question under investigation when the observation (Table IV) which proved to be the source of this paper was made, was whether the sera of rats immunised against normal or malignant homologous cells were isohaemolytic. Table II shows the results in one of many experiments which invariably ag ...
Serpent regulates Drosophila immunity genes in the larval fat body
Serpent regulates Drosophila immunity genes in the larval fat body

Proteomic profiling of an opportunistic human and animal
Proteomic profiling of an opportunistic human and animal

Characterization of CD56 CD16 natural killer (NK) cells: A highly
Characterization of CD56 CD16 natural killer (NK) cells: A highly

... family of the C-type lectin proteins. Diminution or absence of expression of HLA-I molecules on the cell surface because of viral infection or tumor transformation results in reduced engagement of iNKRs; loss of this dominant-negative signal in turn allows a large group of activating NK receptors an ...
Tackling both sides of the host–pathogen
Tackling both sides of the host–pathogen

The Gale Encyclopedia of Biology Vol. 1 A
The Gale Encyclopedia of Biology Vol. 1 A

... How can a single book, or even a four-volume encyclopedia, encompass so vast a subject? It can’t. And in producing Biology, we didn’t try to cover every topic from Aardvark to Zyzzyva. Instead, in our 432 entries we present as broad an introduction as possible to the many facets of biology, while co ...
Toll-like Receptors in the Vascular System
Toll-like Receptors in the Vascular System

Lewis -Containing Oligosaccharide Attenuates Schistosome Egg
Lewis -Containing Oligosaccharide Attenuates Schistosome Egg

... eggs, which is accompanied by induction of a variety of host immune reactions [1]. Importantly, SEA induces a predominant Th-2 type immune responses in murine as well as human schistosomal infection [2–5]. SEA are highly glycosylated [6, 7], and the glycoprotein fractions of SEA appear to be immunog ...
Immune profile from high-risk to onset of Type 1 diabetes No. 1275
Immune profile from high-risk to onset of Type 1 diabetes No. 1275

... Type 1 diabetes (T1D) is most often diagnosed early in life and is usually the result of an autoimmune attack on the insulin producing β-cells of the pancreas, leading to a lack of insulin secretion and life-long insulin treatment. The search for possible targets pin-pointing the β-cell destruction ...
UNIVERSIDAD DE MURCIA FACULTAD DE VETERINARIA  In vivo
UNIVERSIDAD DE MURCIA FACULTAD DE VETERINARIA In vivo

... First. Considering the central importance of MØ for PRRS pathogenesis and the role of IFNs and cytokines in regulating MØ functions, we hypothesized that PRRSV of different virulence should differ in their interaction with cytokine-modulated MØ. To test this, IFN-γ-(M1), IL-4-(M2) and IFN-β-activate ...
the program guide
the program guide

... Pratibha Shah is one of the leading ayurveda experts in the New England area. Her life mission is to propagate healthier ways of living with holistic solutions for illnesses as the primary form of care and to advocate for the integration of holistic care practices into mainstream healthcare. She str ...
Local immune regulation in human pregnancy  Charlotte Gustafsson
Local immune regulation in human pregnancy Charlotte Gustafsson

... During pregnancy, the woman carries a fetus partly foreign to her immune system, because of the expression of paternal antigens. Despite this, the fetus is normally tolerated and not rejected, as is often the case with organs in allogeneic transplantations. Systemic changes in maternal blood occur d ...
fmd with viaa test incl.
fmd with viaa test incl.

... Equine influenza is caused by two subtypes: H7N7 (formerly subtype 1) and H3N8 (formerly subtype 2) of influenza A viruses (genus Influenzavirus A of the family Orthomyxoviridae); however there have been very few reports of H7N7 subtype virus infections in the last 30 years (Webster, 1993). In fully ...
Acute phase response in Chinese soft
Acute phase response in Chinese soft

... protein (APP). In this study, a turtle SAA homologue was identified and described in reptiles. The fulllength cDNA of turtle SAA was 554 bp and contained a 381 bp open reading frame (ORF) coding for a protein of 127 aa. Similar to other known SAA genes, the turtle SAA gene contained three exons and t ...
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Molecular mimicry

Molecular mimicry is defined as the theoretical possibility that sequence similarities between foreign and self-peptides are sufficient to result in the cross-activation of autoreactive T or B cells by pathogen-derived peptides. Despite the promiscuity of several peptide sequences which can be both foreign and self in nature, a single antibody or TCR (T cell receptor) can be activated by even a few crucial residues which stresses the importance of structural homology in the theory of molecular mimicry. Upon the activation of B or T cells, it is believed that these ""peptide mimic"" specific T or B cells can cross-react with self-epitopes, thus leading to tissue pathology (autoimmunity). Molecular mimicry is a phenomenon that has been just recently discovered as one of several ways in which autoimmunity can be evoked. A molecular mimicking event is, however, more than an epiphenomenon despite its low statistical probability of occurring and these events have serious implications in the onset of many human autoimmune disorders. In the past decade the study of autoimmunity, the failure to recognize self antigens as ""self,"" has grown immensely. Autoimmunity is a result of a loss of immunological tolerance, the ability for an individual to discriminate between self and non-self. Growth in the field of autoimmunity has resulted in more and more frequent diagnosis of autoimmune diseases. Consequently, recent data show that autoimmune diseases affect approximately 1 in 31 people within the general population. Growth has also led to a greater characterization of what autoimmunity is and how it can be studied and treated. With an increased amount of research, there has been tremendous growth in the study of the several different ways in which autoimmunity can occur, one of which is molecular mimicry. The mechanism by which pathogens have evolved, or obtained by chance, similar amino acid sequences or the homologous three-dimensional crystal structure of immunodominant epitopes remains a mystery.
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