PowerPoint
... – bind to antibodies which coat infected or malignant cells (antibodydependent cell-mediated cytotoxicity (ADCC) – recognizes cells that have lost their class I major histocompatibility antigen due to presence of virus or cancer ...
... – bind to antibodies which coat infected or malignant cells (antibodydependent cell-mediated cytotoxicity (ADCC) – recognizes cells that have lost their class I major histocompatibility antigen due to presence of virus or cancer ...
Slide 1
... include: • stem cell transplantation • Stem cell strategies for the repair of damaged organ and gene therapy • MSCs due to their immunomodulatory potential theoretically, they can be used allogenically ...
... include: • stem cell transplantation • Stem cell strategies for the repair of damaged organ and gene therapy • MSCs due to their immunomodulatory potential theoretically, they can be used allogenically ...
Document
... O Lamprey and Hagfish have a distinct lymphocyte derived molecule. O These molecules are believed to bind pathogenic antigens in a similar way to antibodies. ...
... O Lamprey and Hagfish have a distinct lymphocyte derived molecule. O These molecules are believed to bind pathogenic antigens in a similar way to antibodies. ...
Airgas template
... lymphocytes) are formed in the bone marrow. The life span of white blood cells is relatively long, so constant renewal is not necessary to maintain normal blood levels. In neutropenia, all of the cell lines are affected, resulting in anemia, thrombocytopenia, and agranulocytosis. Infectious mononucl ...
... lymphocytes) are formed in the bone marrow. The life span of white blood cells is relatively long, so constant renewal is not necessary to maintain normal blood levels. In neutropenia, all of the cell lines are affected, resulting in anemia, thrombocytopenia, and agranulocytosis. Infectious mononucl ...
File
... Toxins produced by pathogens Dead pathogens These all act as antigens – when injected into the body, they stimulate white blood cells to produce antibodies against the pathogen ...
... Toxins produced by pathogens Dead pathogens These all act as antigens – when injected into the body, they stimulate white blood cells to produce antibodies against the pathogen ...
Dr. Charles Egwuagu - Society for Leukocyte Biology
... (NIH) in Bethesda, MD. He received his PhD from Yale University and MPH from Yale’s School of Medicine. After completing his graduate studies, he did a research fellowship at NIH and served as a Commissioned Officer of the US Public Health Service, working his way up to the rank of Captain (06). He ...
... (NIH) in Bethesda, MD. He received his PhD from Yale University and MPH from Yale’s School of Medicine. After completing his graduate studies, he did a research fellowship at NIH and served as a Commissioned Officer of the US Public Health Service, working his way up to the rank of Captain (06). He ...
Immune system and Cancer
... Innate (nonspecific) defense Internal defenses - fever - systemic response - Hypothalamus in the brain regulates body temperature - Pyrogens resets the temperature higher - secreted by macrophages and leukocytes exposed to foreign matter ...
... Innate (nonspecific) defense Internal defenses - fever - systemic response - Hypothalamus in the brain regulates body temperature - Pyrogens resets the temperature higher - secreted by macrophages and leukocytes exposed to foreign matter ...
Reprint - Immune Tolerance Network
... Autoimmunity occurs when T cells, B cells or both are inappropriately activated, resulting in damage to one or more organ systems. Normally, high-affinity self-reactive T and B cells are eliminated in the thymus and bone marrow through a process known as central immune tolerance. However, low-affini ...
... Autoimmunity occurs when T cells, B cells or both are inappropriately activated, resulting in damage to one or more organ systems. Normally, high-affinity self-reactive T and B cells are eliminated in the thymus and bone marrow through a process known as central immune tolerance. However, low-affini ...
notes
... Somatic mutation multiple mutation of the solution Affinity maturation Mutation and selection of best solution Receptor editing Diversification ...
... Somatic mutation multiple mutation of the solution Affinity maturation Mutation and selection of best solution Receptor editing Diversification ...
Chapter 4 Histology
... • Patch between cells holding them together – cells spanned by filaments terminating on protein plaque • cytoplasmic intermediate filaments also attach to plaque • Uterus, heart and epidermis ...
... • Patch between cells holding them together – cells spanned by filaments terminating on protein plaque • cytoplasmic intermediate filaments also attach to plaque • Uterus, heart and epidermis ...
See presentation #4
... • Grown from BM mononuclear cells by their adherence to plastic in tissue culture flasks ...
... • Grown from BM mononuclear cells by their adherence to plastic in tissue culture flasks ...
Chapter 8: The Immune Response
... 3. When this patient is given tetanus toxoid, the immunization utilized for protection against tetanus, he is given a substance that will cause an active immune response. Which two types of lymphocytes will be involved in this immune response and how does each stimulate the immune response? Remember ...
... 3. When this patient is given tetanus toxoid, the immunization utilized for protection against tetanus, he is given a substance that will cause an active immune response. Which two types of lymphocytes will be involved in this immune response and how does each stimulate the immune response? Remember ...
Chapter 21
... TH cells bind to antigen linked to class II MHC proteins Mobile APCs (Langerhans’ cells) quickly alert the body to the presence of antigen by migrating to the lymph nodes and presenting antigen TC cells are activated by antigen fragments complexed with class I MHC proteins APCs produce co-stimulator ...
... TH cells bind to antigen linked to class II MHC proteins Mobile APCs (Langerhans’ cells) quickly alert the body to the presence of antigen by migrating to the lymph nodes and presenting antigen TC cells are activated by antigen fragments complexed with class I MHC proteins APCs produce co-stimulator ...
Review Set Unit 2, Lesson 1 *The Immune System*
... have in common? • defends the body against pathogens • description of immune response, including entry of pathogen or foreign particle and roles of three specified cells (e.g., If pathogens enter the body, macrophages engulf and digest them; T cells coordinate the response and attack infected cells; ...
... have in common? • defends the body against pathogens • description of immune response, including entry of pathogen or foreign particle and roles of three specified cells (e.g., If pathogens enter the body, macrophages engulf and digest them; T cells coordinate the response and attack infected cells; ...
Physiology of Human Development (MCB 135K)
... A. The Ig A class of immunoglobulin is found in breast milk. B. The bone marrow produces stem cells from which ALL lymphocytes are derived. C. The response to viral infections often involves T killer cells. D. Macrophages and neutrophils have phagocytic and antigen processing and presentation activi ...
... A. The Ig A class of immunoglobulin is found in breast milk. B. The bone marrow produces stem cells from which ALL lymphocytes are derived. C. The response to viral infections often involves T killer cells. D. Macrophages and neutrophils have phagocytic and antigen processing and presentation activi ...
The Atlantic salmon immune response to viruses, bacteria and
... and used to detect potential viral suppression. Transcription factors such as GATA3 were discovered and can be used as a marker of the Th2 adaptive response. Finally, the precise analysis of genes induced by IPNV in vaccinated fish shed some light on some aspect of viral infection and the importance ...
... and used to detect potential viral suppression. Transcription factors such as GATA3 were discovered and can be used as a marker of the Th2 adaptive response. Finally, the precise analysis of genes induced by IPNV in vaccinated fish shed some light on some aspect of viral infection and the importance ...
Ralph Steinman and the Discovery of Dendritic Cells Dec. 7 , 2011
... During the Steady State, Dendritic Cells Induce Tolerance, So That During Infection, Dendritic Cell Maturation Does Not Lead to Autoimmunity and Chronic Inflammation Self and harmless environmental antigens ...
... During the Steady State, Dendritic Cells Induce Tolerance, So That During Infection, Dendritic Cell Maturation Does Not Lead to Autoimmunity and Chronic Inflammation Self and harmless environmental antigens ...
Folie 1
... • used splenectomized lymphotoxin-alpha (LTa)-deficient mice (Lta-/-), which as a result of their deficiency already lacked lymph nodes and Peyer’s patches • animals, devoid of secondary lymphoid organs, were reconstituted with wild-type bone marrow (SLP mice) • compared to irradiated C57BL/6 mice t ...
... • used splenectomized lymphotoxin-alpha (LTa)-deficient mice (Lta-/-), which as a result of their deficiency already lacked lymph nodes and Peyer’s patches • animals, devoid of secondary lymphoid organs, were reconstituted with wild-type bone marrow (SLP mice) • compared to irradiated C57BL/6 mice t ...
1 Defenders of the Body 2 Nonspecific Defenses 3 Specific
... – Self is inaccurately regarded as non-self – The immune system attacks the body’s own tissues – “Autoimmune disorder” ...
... – Self is inaccurately regarded as non-self – The immune system attacks the body’s own tissues – “Autoimmune disorder” ...
B cells
... Antibodies as Tools • Antibody specificity and antigen-antibody binding have been harnessed in research, diagnosis, and therapy • Polyclonal antibodies, produced following exposure to a microbial antigen, are products of many different clones of plasma cells, each specific for a different epitope • ...
... Antibodies as Tools • Antibody specificity and antigen-antibody binding have been harnessed in research, diagnosis, and therapy • Polyclonal antibodies, produced following exposure to a microbial antigen, are products of many different clones of plasma cells, each specific for a different epitope • ...
Chapter 22
... variable and constant regions. (Fig. 22.13). The variable region, which is outside the membrane, will have a specific antigen binding site. Thus a clone of Tcells, having the same receptor, will bind only a specific antigenic determinant of an antigen. The other T-cells may have different antigen bi ...
... variable and constant regions. (Fig. 22.13). The variable region, which is outside the membrane, will have a specific antigen binding site. Thus a clone of Tcells, having the same receptor, will bind only a specific antigenic determinant of an antigen. The other T-cells may have different antigen bi ...