thesis - KI Open Archive
... in significantly reduced natural cytotoxicity and antibody-dependent cellular cytotoxicity (ADCC) against autologous carcinoma cells. The DNAM-1 loss was likely caused by chronic ligand exposure, since physical interactions between the receptor and its ligand CD155 induced down-regulation. Suppresse ...
... in significantly reduced natural cytotoxicity and antibody-dependent cellular cytotoxicity (ADCC) against autologous carcinoma cells. The DNAM-1 loss was likely caused by chronic ligand exposure, since physical interactions between the receptor and its ligand CD155 induced down-regulation. Suppresse ...
Psoriasis and Stress–Psoriasis Aspect of Psychoneuroendocrinology
... response to stressors when their action is prolonged (Selye, 1936). Therefore as pointed out for the first time by Hans Selye in Nature in 1936, stress or ‘noxious agents’ initiate a reaction in the body, which he called the ‘general adaptation syndrome’ (GAS). Selye distinguished three stages that ...
... response to stressors when their action is prolonged (Selye, 1936). Therefore as pointed out for the first time by Hans Selye in Nature in 1936, stress or ‘noxious agents’ initiate a reaction in the body, which he called the ‘general adaptation syndrome’ (GAS). Selye distinguished three stages that ...
The Pathogenesis of Rheumatoid Arthritis
... Many other identified risk alleles in ACPApositive rheumatoid arthritis consistently aggregate functionally with immune regulation (Table 1), implicating nuclear factor κB (NF-κB)–dependent signaling (e.g., TRAF1–C5 and c-REL) and T-cell stimulation, activation, and functional differentiation (e.g. ...
... Many other identified risk alleles in ACPApositive rheumatoid arthritis consistently aggregate functionally with immune regulation (Table 1), implicating nuclear factor κB (NF-κB)–dependent signaling (e.g., TRAF1–C5 and c-REL) and T-cell stimulation, activation, and functional differentiation (e.g. ...
Doctoral thesis from the Department of Immunology, the Wenner-Gren Institute,
... life and start to resemble the phenotype of adults after five years of age. Early alterations in the NKcell populations could lead to insufficient Th1 priming, with an increased risk to develop allergic disease. Early infection by common herpes viruses can influence NK-cell function and might be one ...
... life and start to resemble the phenotype of adults after five years of age. Early alterations in the NKcell populations could lead to insufficient Th1 priming, with an increased risk to develop allergic disease. Early infection by common herpes viruses can influence NK-cell function and might be one ...
requirements for memory b cell and long lived plasma cell
... CHAPTER 4: CONCLUSION ..................................................................................................... 87 Long-term humoral immunity in protection against disease .................................................... 87 The Role of DCs and ICs in B cell responses ................ ...
... CHAPTER 4: CONCLUSION ..................................................................................................... 87 Long-term humoral immunity in protection against disease .................................................... 87 The Role of DCs and ICs in B cell responses ................ ...
Viruses and Bacteria
... Figure 2, have a membrane, or envelope, surrounding the capsid. The envelope helps the virus enter cells. It consists of proteins, lipids, and glycoproteins (glie koh PROH teenz), which are proteins with attached carbohydrate molecules that are derived from the host cell. Some viruses also contain s ...
... Figure 2, have a membrane, or envelope, surrounding the capsid. The envelope helps the virus enter cells. It consists of proteins, lipids, and glycoproteins (glie koh PROH teenz), which are proteins with attached carbohydrate molecules that are derived from the host cell. Some viruses also contain s ...
Teil 1: „Studies on the extracellular matrix enzyme
... The discovery of the matrix enzyme lysyl oxidase (LOX) emerged from the convergence of mainly two research areas. Already the greek philosopher Hippocrates reported that chronic ingestion of the sweet pea Lathyrus odoratus can result in a disease today referred to as lathyrism. Studies with experime ...
... The discovery of the matrix enzyme lysyl oxidase (LOX) emerged from the convergence of mainly two research areas. Already the greek philosopher Hippocrates reported that chronic ingestion of the sweet pea Lathyrus odoratus can result in a disease today referred to as lathyrism. Studies with experime ...
Immune tolerance by interferon-alpha in experimental arthritis Jaya Prakash Chalise Linköping University
... Effect of IFN-α on the humoral response during AIA: IFN-α has limited effect on humoral response (Paper I and II)................................................................................................................... 36 Effect of IFN-α on T cells during AIA: IFN-α inhibits antigen-specif ...
... Effect of IFN-α on the humoral response during AIA: IFN-α has limited effect on humoral response (Paper I and II)................................................................................................................... 36 Effect of IFN-α on T cells during AIA: IFN-α inhibits antigen-specif ...
universidad de córdoba facultad de veterinaria
... clinical signs will depend on the nature of secondary infection, so that almost never are recognized as processes induced by BVDV (Brownlie, 1990; Rickey, 1996; Bolin and Grooms, 2004). Acute infection with characteristic clinical symptoms is described as ...
... clinical signs will depend on the nature of secondary infection, so that almost never are recognized as processes induced by BVDV (Brownlie, 1990; Rickey, 1996; Bolin and Grooms, 2004). Acute infection with characteristic clinical symptoms is described as ...
Function of the Drosophila TGF-a homolog Spitz is controlled by Star
... sandwich assay has been shown to require both Star and Rhomboid (Bang and Kintner, 2000). The very fact that Star nulls are haploinsuf®cient dominant mutations with a rough eye phenotype indicates that Star is genetically dose sensitive and suggests that Star function may be quantitatively limiting ...
... sandwich assay has been shown to require both Star and Rhomboid (Bang and Kintner, 2000). The very fact that Star nulls are haploinsuf®cient dominant mutations with a rough eye phenotype indicates that Star is genetically dose sensitive and suggests that Star function may be quantitatively limiting ...
EFFECTS OF INCREASED INFLAMMATION ON ANTIVIRAL CD8 T CELL
... Figure 1. Kinetics for CD8+ T cells going through expansion, contraction and memory T cell formation phase following a viral infection................................................................................................................... 4 Figure 2. Processing of endogenous protein to pe ...
... Figure 1. Kinetics for CD8+ T cells going through expansion, contraction and memory T cell formation phase following a viral infection................................................................................................................... 4 Figure 2. Processing of endogenous protein to pe ...
Stable individual differences in physiological response
... thought to be associated with greater stressor-induced alterations (mostly suppression) of immunity. In turn, the tendency to show more extreme immune reactions to stressors is thought to characterize vulnerability to stress-induced changes in host resistance to infectious agents. Those typically re ...
... thought to be associated with greater stressor-induced alterations (mostly suppression) of immunity. In turn, the tendency to show more extreme immune reactions to stressors is thought to characterize vulnerability to stress-induced changes in host resistance to infectious agents. Those typically re ...
Nonspecific Defenses
... The body produces many types of lymphocytes: – each fights a different type of antigen – active lymphocyte clones itself to fight specific antigen ...
... The body produces many types of lymphocytes: – each fights a different type of antigen – active lymphocyte clones itself to fight specific antigen ...
Clinical pathogenesis of typhoid fever
... The second clinical observation is the following: patients with chronic granulomatous disease (CGD), a primary immunodeficiency preventing the generation of phagocyte oxidative burst, are more susceptible to infection with NTS and frequently develop bacteraemia [48]. However, there is no positive co ...
... The second clinical observation is the following: patients with chronic granulomatous disease (CGD), a primary immunodeficiency preventing the generation of phagocyte oxidative burst, are more susceptible to infection with NTS and frequently develop bacteraemia [48]. However, there is no positive co ...
BioE HIV AIDS
... kill because of their ability to infect and kill other types of cells, while other strains replicate at faster rates. The more virulent and infectious strains of HIV are typically found in people who are in the late stages of infection. Different strains of HIV can also recombine to produce an even ...
... kill because of their ability to infect and kill other types of cells, while other strains replicate at faster rates. The more virulent and infectious strains of HIV are typically found in people who are in the late stages of infection. Different strains of HIV can also recombine to produce an even ...
Stress and immunity in wild vertebrates: Timing is everything
... stress hormones indirectly leads to the appearance of novel selfantigens due to degradation of tissues; immune activity must be depressed to decrease collateral damage to self (Råberg et al., 1998). Immune responses to antigens upon first encounter are typically polyclonal (Sapolsky et al., 2000), me ...
... stress hormones indirectly leads to the appearance of novel selfantigens due to degradation of tissues; immune activity must be depressed to decrease collateral damage to self (Råberg et al., 1998). Immune responses to antigens upon first encounter are typically polyclonal (Sapolsky et al., 2000), me ...