Vaginal microbiota and its role in HIV transmission and infection
... exhibits relatively high levels prior to menstruation (Giª 2013 Federation of European Microbiological Societies Published by John Wiley & Sons Ltd. All rights reserved ...
... exhibits relatively high levels prior to menstruation (Giª 2013 Federation of European Microbiological Societies Published by John Wiley & Sons Ltd. All rights reserved ...
8th Seeon Conference and Science Camp
... To investigate, if the altered microbial composition of Casp8∆IEC mice drives intestinal inflammation, we performed faecal microbiota transplantation (FMT) experiments in which we reconstituted germ free wild type mice, with Casp8∆IEC and control microflora. Mice treated with Casp8∆IEC microflora sh ...
... To investigate, if the altered microbial composition of Casp8∆IEC mice drives intestinal inflammation, we performed faecal microbiota transplantation (FMT) experiments in which we reconstituted germ free wild type mice, with Casp8∆IEC and control microflora. Mice treated with Casp8∆IEC microflora sh ...
Recognition of bacteria by inflammasomes.
... Generic model of inflammasome activation. Cytosolic nucleotide-binding domain, leucine-rich repeat (NBD-LRR) proteins are maintained in an autoinhibited state until ligand recognition and ATP binding drive oligomerization via the NBD domain. Recruitment of CASP1 to form the inflammasome complex occu ...
... Generic model of inflammasome activation. Cytosolic nucleotide-binding domain, leucine-rich repeat (NBD-LRR) proteins are maintained in an autoinhibited state until ligand recognition and ATP binding drive oligomerization via the NBD domain. Recruitment of CASP1 to form the inflammasome complex occu ...
and Adaptive Immune Responses an Endogenous
... cans are proposed to bridge innate and adaptive immune recognition and response (3). This realization led to a growing interest in Abs to carbohydrate (glycan)-based Ags, as cellular and humoral immune responses rely heavily on interactions between glycans and specific glycan-binding proteins (4). O ...
... cans are proposed to bridge innate and adaptive immune recognition and response (3). This realization led to a growing interest in Abs to carbohydrate (glycan)-based Ags, as cellular and humoral immune responses rely heavily on interactions between glycans and specific glycan-binding proteins (4). O ...
Combinations of type 1 diabetes, celiac disease and allergy
... To me, myself, and I. With love. ...
... To me, myself, and I. With love. ...
Vaccination - The Open University
... Since the smallpox virus was declared eradicated ‘in the wild’ in 1980, stocks of virus have been held in secure laboratories in various parts of the world, with the expectation that they would eventually be destroyed. However, since 2001, the perceived threat of bioterrorism has led to debates abou ...
... Since the smallpox virus was declared eradicated ‘in the wild’ in 1980, stocks of virus have been held in secure laboratories in various parts of the world, with the expectation that they would eventually be destroyed. However, since 2001, the perceived threat of bioterrorism has led to debates abou ...
Vaccinia virus protein A46R targets multiple Toll-like
... Cell surface TLR2 and TLR4 may recognize viral glycoproteins on virions (8, 9). For example, measles virus hemagglutinin activates murine and human cells via TLR2, leading to induction of proinflammatory cytokines and up-regulation of surface expression of CD150, a receptor for measles virus (10). I ...
... Cell surface TLR2 and TLR4 may recognize viral glycoproteins on virions (8, 9). For example, measles virus hemagglutinin activates murine and human cells via TLR2, leading to induction of proinflammatory cytokines and up-regulation of surface expression of CD150, a receptor for measles virus (10). I ...
The parasitic wasp Cotesia congregata uses multiple mechanisms
... 1 h, followed by alkylation in 200 µl of 25 mM NH4HCO3 containing 55 mM iodoacetamide in the dark at room temperature for 45 min. The reduced and alkylated gel pieces were then washed 2 times with 100 µl of 25 mM NH4HCO3 and 50% ACN with 25 mM NH4HCO3 for 10 min. Gel pieces were dehydrated with 200 ...
... 1 h, followed by alkylation in 200 µl of 25 mM NH4HCO3 containing 55 mM iodoacetamide in the dark at room temperature for 45 min. The reduced and alkylated gel pieces were then washed 2 times with 100 µl of 25 mM NH4HCO3 and 50% ACN with 25 mM NH4HCO3 for 10 min. Gel pieces were dehydrated with 200 ...
Small intestinal eosinophils regulate Th17 cells by producing IL
... E osinophils play proinflammatory roles in helminth infections and allergic diseases. Under steady-state conditions, eosinophils are abundantly found in the small intestinal lamina propria, but their physiological function is largely unexplored. In this study, we found that small intestinal eosinoph ...
... E osinophils play proinflammatory roles in helminth infections and allergic diseases. Under steady-state conditions, eosinophils are abundantly found in the small intestinal lamina propria, but their physiological function is largely unexplored. In this study, we found that small intestinal eosinoph ...
Small intestinal eosinophils regulate Th17 cells by producing IL
... E osinophils play proinflammatory roles in helminth infections and allergic diseases. Under steady-state conditions, eosinophils are abundantly found in the small intestinal lamina propria, but their physiological function is largely unexplored. In this study, we found that small intestinal eosinoph ...
... E osinophils play proinflammatory roles in helminth infections and allergic diseases. Under steady-state conditions, eosinophils are abundantly found in the small intestinal lamina propria, but their physiological function is largely unexplored. In this study, we found that small intestinal eosinoph ...
Alopecia areata update
... pathogenesis of the disease remains to be clarified. Disease prevalence rates from 0.1% to 0.2% have been estimated for the United States. AA can affect any hair-bearing area. It often presents as well demarcated patches of nonscarring alopecia on skin of overtly normal appearance. Recently, newer c ...
... pathogenesis of the disease remains to be clarified. Disease prevalence rates from 0.1% to 0.2% have been estimated for the United States. AA can affect any hair-bearing area. It often presents as well demarcated patches of nonscarring alopecia on skin of overtly normal appearance. Recently, newer c ...
Hemophagocytosis in adults (Hemophagocytic Syndrome) Brady Miller Hematology Oncology Fellow
... – Underlying conditions include infections, autoimmune diseases, malignancies, and immune suppression/organ transplantation. – As in primary HLH, the cytoxic activity of the NK and CTLs are blocked. The mechanisms that lead to this in acquired HLH are not clear. Some hypotheses include: • Viruses ma ...
... – Underlying conditions include infections, autoimmune diseases, malignancies, and immune suppression/organ transplantation. – As in primary HLH, the cytoxic activity of the NK and CTLs are blocked. The mechanisms that lead to this in acquired HLH are not clear. Some hypotheses include: • Viruses ma ...
Beyond Hemostasis: The Role of Platelets in Inflammation and Infection Archibald McNicol
... E-mail: [email protected] 1871-529X/08 $55.00+.00 ...
... E-mail: [email protected] 1871-529X/08 $55.00+.00 ...
Metchnikoff and the phagocytosis theory - BU Blogs
... century. Indeed, the clonal selection theory and the elucidation of the molecular biology of the immune response count among the great advances in biology during our own era5. Metchnikoff has been assigned to the wine cellar of history, to be pulled out on occasion and celebrated as an old hero. How ...
... century. Indeed, the clonal selection theory and the elucidation of the molecular biology of the immune response count among the great advances in biology during our own era5. Metchnikoff has been assigned to the wine cellar of history, to be pulled out on occasion and celebrated as an old hero. How ...
Purification, Characterization and Antibacterial Mechanism of
... lactate dehydrogenase macromolecules led to disruption of cellular matter and energy metabolism. The concentration of intracellular K+ of E. coli decreased rapidly, which resulted in the imbalance of membrane potential. To maintain the membrane potential, the intracellular ATP was consumed. This cou ...
... lactate dehydrogenase macromolecules led to disruption of cellular matter and energy metabolism. The concentration of intracellular K+ of E. coli decreased rapidly, which resulted in the imbalance of membrane potential. To maintain the membrane potential, the intracellular ATP was consumed. This cou ...
In July 2004, The Training Program Director`s Core Curriculum and
... 7. B cell mediated immunity.................................................................................................... 45 a. B cell activation – cytokines and signal transduction ...................................................... 46 b. Epitope recognition and immunoglobulin production ...
... 7. B cell mediated immunity.................................................................................................... 45 a. B cell activation – cytokines and signal transduction ...................................................... 46 b. Epitope recognition and immunoglobulin production ...
Caco-2, HT-29, HT29 MTX
... term probiotic was defined more than 20 years ago and is usually defined as live microorganisms or microbial food supplements that confer health benefits for the host, when administered in adequate amounts (Reid et al., 2003). Most probiotics fall into the group of organisms known as lactic acid pro ...
... term probiotic was defined more than 20 years ago and is usually defined as live microorganisms or microbial food supplements that confer health benefits for the host, when administered in adequate amounts (Reid et al., 2003). Most probiotics fall into the group of organisms known as lactic acid pro ...
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... capability to actually produce POMC as well as CRH peptides and to also express the corresponding receptors. Cutaneous modulation of CRH and POMC production could be mediated by proinflammatory cytokines, as is the case at the systemic level. Thus the skin expresses an equivalent of the HPA axis tha ...
... capability to actually produce POMC as well as CRH peptides and to also express the corresponding receptors. Cutaneous modulation of CRH and POMC production could be mediated by proinflammatory cytokines, as is the case at the systemic level. Thus the skin expresses an equivalent of the HPA axis tha ...
Neutrophil function in the healing wound: adding insult to injury?
... pulmonary diseases (37-39), as well as autoimmune diseases, such as Wegener’s granulomatosis (40, 41). The molecular mechanism of endothelial damage in patients suffering from Wegener’s granulomatosis, characterized by systemic vasculitis, is particularly interesting. The binding of anti-neutrophil ...
... pulmonary diseases (37-39), as well as autoimmune diseases, such as Wegener’s granulomatosis (40, 41). The molecular mechanism of endothelial damage in patients suffering from Wegener’s granulomatosis, characterized by systemic vasculitis, is particularly interesting. The binding of anti-neutrophil ...
The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases
... expressed on murine Th2 cells (Figure 3; Table 1) expressing predominantly IL-4, IL-5, or IL-10, but not IFN-γ or IL-2 (40, 85). Its expression is independent of IL-4, IL-5, and IL-10, as loss of any of these cytokines does not affect ST2 expression on Th2 cells (40). ST2 expression on Th2 cells i ...
... expressed on murine Th2 cells (Figure 3; Table 1) expressing predominantly IL-4, IL-5, or IL-10, but not IFN-γ or IL-2 (40, 85). Its expression is independent of IL-4, IL-5, and IL-10, as loss of any of these cytokines does not affect ST2 expression on Th2 cells (40). ST2 expression on Th2 cells i ...
epstein-barr virus
... the viral envelope glycoprotein gp350/220 with the cellular receptor for the C3d complement component CR2 (CD21) (Fingeroth et al., 1984, 1988; Tanner et al., 1987). After binding of the viral particle to the surface of the host cell and endocytosis, the viral envelope fuses with the host-cell membr ...
... the viral envelope glycoprotein gp350/220 with the cellular receptor for the C3d complement component CR2 (CD21) (Fingeroth et al., 1984, 1988; Tanner et al., 1987). After binding of the viral particle to the surface of the host cell and endocytosis, the viral envelope fuses with the host-cell membr ...